Functionalized MoS2-nanosheets with NIR-Triggered nitric oxide delivery and photothermal activities for synergistic antibacterial and regeneration-promoting therapy
Bacterial infection in skin and soft tissue has emerged as a critical concern. Overreliance on antibiotic therapy has led to numerous challenges, including the emergence of multidrug-resistant bacteria and adv... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 4, 2023 Category: Nanotechnology Authors: Zhixiang Mu, Ting Jin, Tengda Chu, Hongyang Lu, Yuanqi Chen, Sisi Li, BaiRui Zeng, Chen Huang, Kezheng Lei, Xiaojun Cai, Hui Deng and Rongdang Hu Tags: Research Source Type: research
Correction: Injectable hydrogel loaded with lysed OK-432 and doxorubicin for residual liver cancer after incomplete radiofrequency ablation
(Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 4, 2023 Category: Nanotechnology Authors: Yanyan Cao, Tao Sun, Bo Sun, Guilin Zhang, Jiayun Liu, Bin Liang, Chuansheng Zheng and Xuefeng Kan Tags: Correction Source Type: research
Nano-modulators with the function of disrupting mitochondrial Ca2+ homeostasis and photothermal conversion for synergistic breast cancer therapy
Breast cancer treatment has been a global puzzle, and apoptosis strategies based on mitochondrial Ca2+ overload have attracted extensive attention. However, various limitations of current Ca2+ nanogenerators make... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 4, 2023 Category: Nanotechnology Authors: Chenglong Wang, Tao Li, Zhen Wang, Yao Li, Yan Liu, Maochang Xu, Zongquan Zhang, Yiping Deng, Liang Cai, Chunxiang Zhang and Chunhong Li Tags: Research Source Type: research
Mesenchymal stem cells-derived extracellular vesicles protect against oxidative stress-induced xenogeneic biological root injury via adaptive regulation of the PI3K/Akt/NRF2 pathway
Xenogeneic extracellular matrices (xECM) for cell support have emerged as a potential strategy for addressing the scarcity of donor matrices for allotransplantation. However, the poor survival rate or failure ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 4, 2023 Category: Nanotechnology Authors: Haojie Fu, Lin Sen, Fangqi Zhang, Sirui Liu, Meiyue Wang, Hongyan Mi, Mengzhe Liu, Bingyan Li, Shumin Peng, Zelong Hu, Jingjing Sun and Rui Li Tags: Research Source Type: research
Ropivacaine-loaded hydrogels for prolonged relief of chemotherapy-induced peripheral neuropathic pain and potentiated chemotherapy
Chemotherapy can cause severe pain for patients, but there are currently no satisfactory methods of pain relief. Enhancing the efficacy of chemotherapy to reduce the side effects of high-dose chemotherapeutic ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 2, 2023 Category: Nanotechnology Authors: Xin Qing, Renbin Dou, Peng Wang, Mengni Zhou, Chenchen Cao, Huiwen Zhang, Gaolin Qiu, Zhilai Yang, Jiqian Zhang, Hu Liu, Shasha Zhu and Xuesheng Liu Tags: Research Source Type: research
Biomimetic composite hydrogel promotes new bone formation in rat bone defects through regulation of miR-19b-3p/WWP1 axis by loaded extracellular vesicles
This study aims to investigate the mechanism by which biomimetic composite hydrogels loaded with bone marrow mesenchymal stem cells (BMSCs) derived microRNA-19b-3p/WWP1 axis through extracellular vesicles (EVs... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 30, 2023 Category: Nanotechnology Authors: Rongkang Guo, Chaohan Wu, Fan Liu, Tianhua Dong and Tao Zhang Tags: Research Source Type: research
Colchicine delivered by a novel nanoparticle platform alleviates atherosclerosis by targeted inhibition of NF- κB/NLRP3 pathways in inflammatory endothelial cells
Atherosclerosis, a chronic inflammatory disease characterized by arterial plaque formation, is one of the most prominent causes of cardiovascular diseases. However, the current treatments often do not adequate... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 30, 2023 Category: Nanotechnology Authors: Juan Tang, Tao Li, Xiaojing Xiong, Qiaoyun Yang, Zedazhong Su, Minming Zheng and Qingwei Chen Tags: Research Source Type: research
Extracellular vesicles in venous thromboembolism and pulmonary hypertension
Venous thromboembolism (VTE) is a multifactorial disease, and pulmonary hypertension (PH) is a serious condition characterized by pulmonary vascular remodeling leading with increased pulmonary vascular resista... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 30, 2023 Category: Nanotechnology Authors: Jiwei Zhang, Xiaoyi Hu, Tao Wang, Rui Xiao, Liping Zhu, Matthieu Ruiz, Jocelyn Dupuis and Qinghua Hu Tags: Review Source Type: research
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells
Reduced supplies of oxygen and nutrients caused by vascular injury lead to difficult-to-heal pressure ulcers (PU) in clinical practice. Rapid vascular repair in the skin wound is the key to the resolution of t... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 29, 2023 Category: Nanotechnology Authors: Liwen Luo, Hongyu Zhang, Shiyu Zhang, Chengqin Luo, Xuewei Kan, Jun Lv, Ping Zhao, Zhiqiang Tian and Changqing Li Tags: Research Source Type: research
Advanced application of nanotechnology in active constituents of Traditional Chinese Medicines
Traditional Chinese Medicines (TCMs) have been used for centuries for the treatment and management of various diseases. However, their effective delivery to targeted sites may be a major challenge due to their... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 29, 2023 Category: Nanotechnology Authors: Chong Qiu, Jun Zhe Zhang, Bo Wu, Cheng Chao Xu, Huan Huan Pang, Qing Chao Tu, Yu Qian Lu, Qiu Yan Guo, Fei Xia and Ji Gang Wang Tags: Review Source Type: research
Visualization of microRNA therapy in cancers delivered by small extracellular vesicles
MicroRNA (miRNA) delivery by extracellular vesicles (EVs) has recently inspired tremendous developments in cancer treatments. However, hybridization between miRNA and its target mRNA is still difficult to be i... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 29, 2023 Category: Nanotechnology Authors: Peiwen Fu, Yumeng Guo, Yanan Luo, Michael Mak, Jianguo Zhang, Wenrong Xu, Hui Qian and Zhimin Tao Tags: Research Source Type: research
SHED-derived exosomes attenuate trigeminal neuralgia after CCI of the infraorbital nerve in mice via the miR-24-3p/IL-1R1/p-p38 MAPK pathway
Microglial activation in the spinal trigeminal nucleus (STN) plays a crucial role in the development of trigeminal neuralgia (TN). The involvement of adenosine monophosphate-activated protein kinase (AMPK) and... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 29, 2023 Category: Nanotechnology Authors: Rong Guo, Yuxin Fang, Yuyao Zhang, Liu Liu, Na Li, Jintao Wu, Ming Yan, Zehan Li and Jinhua Yu Tags: Research Source Type: research
Transplantation of active nucleus pulposus cells with a keep-charging hydrogel microsphere system to rescue intervertebral disc degeneration
Cell transplantation has been demonstrated as a promising approach in tissue regeneration. However, the reactive oxygen species (ROS) accumulation and inflammation condition establish a harsh microenvironment ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 28, 2023 Category: Nanotechnology Authors: Yingchuang Tang, Kai Zhang, Hongyou Zhou, Chenchen Zhang, Zixiang Liu, Hao Chen, Hanwen Li and Kangwu Chen Tags: Research Source Type: research
Recent advances in melittin-based nanoparticles for antitumor treatment: from mechanisms to targeted delivery strategies
As a naturally occurring cytolytic peptide, melittin (MLT) not only exhibits a potent direct tumor cell-killing effect but also possesses various immunomodulatory functions. MLT shows minimal chances for devel... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 28, 2023 Category: Nanotechnology Authors: Xiang Yu, Siyu Jia, Shi Yu, Yaohui Chen, Chengwei Zhang, Haidan Chen and Yanfeng Dai Tags: Review Source Type: research
Micro electrical fields induced MSC-sEVs attenuate neuronal cell apoptosis by activating autophagy via lncRNA MALAT1/miR-22-3p/SIRT1/AMPK axis in spinal cord injury
Spinal cord injury (SCI) is a traumatic condition of the central nervous system that causes paralysis of the limbs. Micro electric fields (EF) have been implicated in a novel therapeutic approach for nerve inj... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 27, 2023 Category: Nanotechnology Authors: Kewei Li, Zhong Liu, Peipei Wu, Shenyuan Chen, Min Wang, Wenhui Liu, Leilei Zhang, Song Guo, Yanbin Liu, Pengcheng Liu, Beiting Zhang, Lin Tao, Hua Ding, Hui Qian and Qiang Fu Tags: Research Source Type: research
