Facile adipocyte uptake and liver/adipose tissue delivery of conjugated linoleic acid-loaded tocol nanocarriers for a synergistic anti-adipogenesis effect
Obesity is a major risk to human health. Adipogenesis is blocked by α-tocopherol and conjugated linoleic acid (CLA). However, their effect at preventing obesity is uncertain. The effectiveness of the bioactive... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 6, 2024 Category: Nanotechnology Authors: Ching-Yun Hsu, Chia-Chih Liao, Zih-Chan Lin, Ahmed Alalaiwe, Erica Hwang, Tzu-Wei Lin and Jia-You Fang Tags: Research Source Type: research

Long-acting anti-inflammatory injectable DEX-Gel with sustained release and self-healing properties regulates TH1/TH2 immune balance for minimally invasive treatment of allergic rhinitis
Allergic rhinitis (AR) is a prevalent immune-related allergic disease, and corticosteroid nasal sprays serve as the primary treatment for this patient population. However, their short duration of efficacy and ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 6, 2024 Category: Nanotechnology Authors: Li Dai, Bin Liu, Jiangtao Lin, Yongquan Jiang, Yuanyuan Li, Zhuowei Yao, Silin Shen, Yiming Jiang, Yourong Duan and Jiping Li Tags: Research Source Type: research

Ginseng-derived nanoparticles alleviate inflammatory bowel disease via the TLR4/MAPK and p62/Nrf2/Keap1 pathways
Inflammatory bowel disease (IBD) is closely linked to the homeostasis of the intestinal environment, and exosomes can be used to treat IBD due to their high biocompatibility and ability to be effectively absor... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - February 1, 2024 Category: Nanotechnology Authors: Song Yang, Wenjing Li, Xueyuan Bai, Giada Di Nunzio, Liangliang Fan, Yueming Zhao, Limei Ren, Ronghua Zhao, Shuai Bian, Meichen Liu, Yuchi Wei, Daqing Zhao and Jiawen Wang Tags: Research Source Type: research

Correction: Bioactive VS4-based sonosensitizer for robust chemodynamic, sonodynamic and osteogenic therapy of infected bone defects
(Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 31, 2024 Category: Nanotechnology Authors: Yaqi He, Xin Liu, Jie Lei, Liang Ma, Xiaoguang Zhang, Hongchuan Wang, Chunchi Lei, Xiaobo Feng, Cao Yang and Yong Gao Tags: Correction Source Type: research

Calcium phosphate coating enhances osteointegration of melt electrowritten scaffold by regulating macrophage polarization
The osteoimmune microenvironment induced by implants plays a significant role in bone regeneration. It is essential to efficiently and timely switch the macrophage phenotype from M1 to M2 for optimal bone heal... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 31, 2024 Category: Nanotechnology Authors: Yubo Shi, Weidong Tao, Wenjing Yang, Lei Wang, Zhennan Qiu, Xiaoli Qu, Jingyi Dang, Jiankang He and Hongbin Fan Tags: Research Source Type: research

Correction: Temporally and spatially resolved molecular profiling in fingerprint analysis using indium vanadate nanosheets-assisted laser desorption ionization mass spectrometry
(Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 30, 2024 Category: Nanotechnology Authors: Yanli Zhu, Jikai Wang, Chengxiao Fu, Shuangquan Liu, Pragati Awasthi, Pengfei Zeng, Danjun Chen, Yiyang Sun, Ziyi Mo and Hailing Liu Tags: Correction Source Type: research

Magnetic resonance imaging with upconversion nanoprobes capable of crossing the blood-cerebrospinal fluid barrier
The central nervous system (CNS) maintains homeostasis with its surrounding environment by restricting the ingress of large hydrophilic molecules, immune cells, pathogens, and other external harmful substances... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 30, 2024 Category: Nanotechnology Authors: Fang Han, Jiahao Gao, Guanglei Lv, Tao Liu, Qingfeng Hu, Meilin Zhu, Zunguo Du, Jing Yang, Zhenwei Yao, Xiangming Fang, Dalong Ni and Jiawen Zhang Tags: Research Source Type: research

Double-layered N-S1 protein nanoparticle immunization elicits robust cellular immune and broad antibody responses against SARS-CoV-2
The COVID-19 pandemic is a persistent global threat to public health. As for the emerging variants of SARS-CoV-2, it is necessary to develop vaccines that can induce broader immune responses, particularly vacc... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 30, 2024 Category: Nanotechnology Authors: Ruiqi Li, Zejie Chang, Hongliang Liu, Yanan Wang, Minghui Li, Yilan Chen, Lu Fan, Siqiao Wang, Xueke Sun, Siyuan Liu, Anchun Cheng, Peiyang Ding and Gaiping Zhang Tags: Research Source Type: research

Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application
Malignancy is a major public health problem and among the leading lethal diseases worldwide. Although the current tumor treatment methods have therapeutic effect to a certain extent, they still have some short... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 28, 2024 Category: Nanotechnology Authors: Qian Yang, Shisheng Li, Haibo Ou, Yuming Zhang, Gangcai Zhu, Shaohong Li and Lanjie Lei Tags: Review Source Type: research

Recent progress of non-linear topological structure polymers: synthesis, and gene delivery
Currently, many types of non-linear topological structure polymers, such as brush-shaped, star, branched and dendritic structures, have captured much attention in the field of gene delivery and nanomedicine. C... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 27, 2024 Category: Nanotechnology Authors: Chenfei Wang, Wei He, Feifei Wang, Haiyang Yong, Tao Bo, Dingjin Yao, Yitong Zhao, Chaolan Pan, Qiaoyu Cao, Si Zhang and Ming Li Tags: Review Source Type: research

Bimodal DNA self-origami material with nucleic acid function enhancement
The design of DNA materials with specific nanostructures for biomedical tissue engineering applications remains a challenge. High-dimensional DNA nanomaterials are difficult to prepare and are unstable; moreov... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 26, 2024 Category: Nanotechnology Authors: Songlin He, Haotian Deng, Peiqi Li, Qinyu Tian, Yongkang Yang, Jingjing Hu, Hao Li, Tianyuan Zhao, Hongkun Ling, Yin Liu, Shuyun Liu and Quanyi Guo Tags: Research Source Type: research

CD44-targeting hyaluronic acid-selenium nanoparticles boost functional recovery following spinal cord injury
Therapeutic strategies based on scavenging reactive oxygen species (ROS) and suppressing inflammatory cascades are effective in improving functional recovery after spinal cord injury (SCI). However, the lack o... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 23, 2024 Category: Nanotechnology Authors: Wenqi Luo, Yueying Li, Jianhui Zhao, Renrui Niu, Chunyu Xiang, Mingyu Zhang, Chunsheng Xiao, Wanguo Liu and Rui Gu Tags: Research Source Type: research

Correction: Microenvironment of pancreatic inflammation: calling for nanotechnology for diagnosis and treatment
(Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 23, 2024 Category: Nanotechnology Authors: Lu Liu, Yiqing Zhang, Xinghui Li and Jun Deng Tags: Correction Source Type: research

Correction: Mesenchymal stem cells ‑derived extracellular vesicles protect against oxidative stress‑induced xenogeneic biological root injury via adaptive regulation of the PI3K/Akt/NRF2 pathway
(Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 22, 2024 Category: Nanotechnology Authors: Haojie Fu, Lin Sen, Fangqi Zhang, Sirui Liu, Meiyue Wang, Hongyan Mi, Mengzhe Liu, Bingyan Li, Shumin Peng, Zelong Hu, Jingjing Sun and Rui Li Tags: Correction Source Type: research

Asymmetric adhesive SIS-based wound dressings for therapeutically targeting wound repair
Severe tissue injuries pose a significant risk to human health. Conventional wound dressings fall short in achieving effective tissue regeneration, resulting in suboptimal postoperative healing outcomes. In th... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - January 19, 2024 Category: Nanotechnology Authors: Wende Yao, Zelong Song, Xiaodong Ma, Yiqian Huang, Xueying Zhang, Yunhuan Li, Pengfei Wei, Julei Zhang, Chenlu Xiong, Sihan Yang, Yujian Xu, Wei Jing, Bo Zhao, Xuesong Zhang and Yan Han Tags: Research Source Type: research