Pericyte-derived exosomal miR-210 improves mitochondrial function and inhibits lipid peroxidation in vascular endothelial cells after traumatic spinal cord injury by activating JAK1/STAT3 signaling pathway
Spinal cord injury (SCI) remains a significant health concern, with limited available treatment options. This condition poses significant medical, economic, and social challenges. SCI is typically categorized ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 27, 2023 Category: Nanotechnology Authors: Peng Gao, Jiang Yi, Wenjun Chen, Jun Gu, Sheng Miao, Xiaowei Wang, Yifan Huang, Tao Jiang, Qingqing Li, Wei Zhou, Shujie Zhao, Mengyuan Wu, Guoyong Yin and Jian Chen Tags: Research Source Type: research
Zn-Shik-PEG nanoparticles alleviate inflammation and multi-organ damage in sepsis
Sepsis is defined as a life-threatening organ dysfunction caused by excessive formation of reactive oxygen species (ROS) and dysregulated inflammatory response. Previous studies have reported that shikonin (Sh... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 25, 2023 Category: Nanotechnology Authors: Jie Guo, Yuqing Miao, Fayi Nie, Fei Gao, Hua Li, Yuan Wang, Qi Liu, Tingbin Zhang, Xiaohang Yang, Li Liu, Haiming Fan, Qiang Wang and Haifa Qiao Tags: Research Source Type: research
Hypoxic preconditioned MSCs-derived small extracellular vesicles for photoreceptor protection in retinal degeneration
Photoreceptor apoptosis is an important pathogenesis of retinal degeneration and a primary cause of vision loss with limited treatment methods. Mesenchymal stem/stromal cells-derived small extracellular vesicl... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 25, 2023 Category: Nanotechnology Authors: Yuntong Sun, Yuntao Sun, Shenyuan Chen, Yifan Yu, Yongjun Ma and Fengtian Sun Tags: Research Source Type: research
Fluorescence-enhanced dual signal lateral flow immunoassay for flexible and ultrasensitive detection of monkeypox virus
In this study, we dev... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 25, 2023 Category: Nanotechnology Authors: Xingsheng Yang, Xiaodan Cheng, Hongjuan Wei, Zhijie Tu, Zhen Rong, Chongwen Wang and Shengqi Wang Tags: Research Source Type: research
Pathologically catalyzed physical coating restores the intestinal barrier for inflammatory bowel disease therapy
Intestinal epithelia impairment of inflammatory bowel disease (IBD) leads to the leakage of bacteria and antigens and the consequent persistent immune imbalance. Restoring the epithelial barrier is a promising... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 24, 2023 Category: Nanotechnology Authors: Yuge Zhao, Ruiqing He, Jie Zang, Weimin Yin, Runping Su, Wei Xiong, Weihua Xu, Jiaxin Zhang, Yiqiong Liu, Tianbin Ren, Yongzhuo Huang and Yongyong Li Tags: Research Source Type: research
Plant-derived nanovesicles: harnessing nature's power for tissue protection and repair
Tissue damage and aging lead to dysfunction, disfigurement, and trauma, posing significant global challenges. Creating a regenerative microenvironment to resist external stimuli and induce stem cell differenti... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 24, 2023 Category: Nanotechnology Authors: Xiaohang Chen, Xiaojie Xing, Shuoqi Lin, Liyu Huang, Lianghang He, Yuchun Zou, Xuyang Zhang, Bohua Su, Youguang Lu and Dali Zheng Tags: Review Source Type: research
Near infrared II excitation nanoplatform for photothermal/chemodynamic/antibiotic synergistic therapy combating bacterial biofilm infections
Drug-resistant bacterial biofilm infections (BBIs) are refractory to elimination. Near-infrared-II photothermal therapy (NIR-II PTT) and chemodynamic therapy (CDT) are emerging antibiofilm approaches because o... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 24, 2023 Category: Nanotechnology Authors: Xuanzong Wang, Chi Zhang, Liuliang He, Mingfei Li, Pengfei Chen, Wan Yang, Pengfei Sun, Daifeng Li and Yi Zhang Tags: Research article Source Type: research
Plasma exosomes improve peripheral neuropathy via miR-20b-3p/Stat3 in type I diabetic rats
Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and the main cause of non-traumatic amputation, with no ideal treatment. Multiple cell-derived exosomes have been report... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 24, 2023 Category: Nanotechnology Authors: Jiayang Li, Guangzhi Wu, Weiye Li, Xiongyao Zhou, Weizhen Li, Xiong Xu, Ke Xu, Rangjuan Cao and Shusen Cui Tags: Research Source Type: research
Targeted delivery of organic small-molecule photothermal materials with engineered extracellular vesicles for imaging-guided tumor photothermal therapy
Imaging-guided photothermal therapy (PTT) for cancers recently gathered increasing focus thanks to its precise diagnosis and potent therapeutic effectiveness. Croconaine (CR) dyes demonstrate potential in expa... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 23, 2023 Category: Nanotechnology Authors: Yafang Dong, Peng Xia, Xiaolong Xu, Jing Shen, Youbin Ding, Yuke Jiang, Huifang Wang, Xin Xie, Xiaodong Zhang, Weihua Li, Zhijie Li, Jigang Wang and Shan-Chao Zhao Tags: Research Source Type: research
Microenvironment of pancreatic inflammation: calling for nanotechnology for diagnosis and treatment
Acute pancreatitis (AP) is a common and life-threatening digestive disorder. However, its diagnosis and treatment are still impeded by our limited understanding of its etiology, pathogenesis, and clinical mani... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 23, 2023 Category: Nanotechnology Authors: Lu Liu, Yiqing Zhang, Xinghui Li and Jun Deng Tags: Review Source Type: research
Biomimetic platelet-camouflaged drug-loaded polypyrrole for the precise targeted antithrombotic therapy
Lower extremity deep venous thrombosis (LEDVT) affects patient ’s quality of life for a long time, and even causes pulmonary embolism, which threatens human health. Current anticoagulant drugs in clinical treat... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 22, 2023 Category: Nanotechnology Authors: Zhining Zhao, Xiaodan Li, Yan Wang, Cheng Liu, Guixia Ling and Peng Zhang Tags: Research Source Type: research
TH-302-loaded nanodrug reshapes the hypoxic tumour microenvironment and enhances PD-1 blockade efficacy in gastric cancer
Hypoxia, a common characteristic of the tumour microenvironment, is involved in tumour progression and immune evasion. Targeting the hypoxic microenvironment has been implicated as a promising antitumour thera... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 22, 2023 Category: Nanotechnology Authors: Zhixiong Wang, Menglin Zhu, Runyu Dong, Danping Cao, Yanna Li, Zhiqiang Chen, Juan Cai and Xueliang Zuo Tags: Research Source Type: research
Potentiating humoral and cellular immunity using a novel hybrid polymer-lipid nanoparticle adjuvant for HBsAg-VLP vaccine
Aluminium adjuvants are commonly used in vaccines to stimulate the immune system, but they have limited ability to promote cellular immunity which is necessary for clearing viral infections like hepatitis B. C... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 22, 2023 Category: Nanotechnology Authors: Xuhan Liu, Qiuxia Min, Huiping Song, Aochun Yue, Qin Li, Qing Zhou and Wei Han Tags: Research Source Type: research
Correction: Dendritic cell hybrid nanovaccine for mild heat inspired cancer immunotherapy
(Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 21, 2023 Category: Nanotechnology Authors: Chen Shi, Chen Jian, Lulu Wang, Chen Gao, Ting Yang, Zhiwen Fu and Tingting Wu Tags: Correction Source Type: research
Carbon nanosol-induced assemblage of a plant-beneficial microbiome consortium
Carbon nanosol (CNS) is a carbon-based nanomaterial that promotes plant growth; however, its functional mechanisms and effects on the microbiome are not fully understood. Here, we explored the effects of CNS o... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 20, 2023 Category: Nanotechnology Authors: Lingtong Cheng, Jiemeng Tao, Zechao Qu, Peng Lu, Taibo Liang, Lijun Meng, Wei Zhang, Nan Liu, Jianfeng Zhang, Peijian Cao and Jingjing Jin Tags: Research Source Type: research
