Ultrasound-targeted microbubble destruction promotes PDGF-primed bone mesenchymal stem cell transplantation for myocardial protection in acute Myocardial Infarction in rats
Ultrasound-targeted microbubble destruction (UTMD) has emerged as a promising strategy for the targeted delivery of bone marrow mesenchymal stem cells (MSCs) to the ischemic myocardium. However, the limited mi... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 15, 2023 Category: Nanotechnology Authors: Zhenxing Sun, Yu Cai, Yihan Chen, Qiaofeng Jin, Ziming Zhang, Li Zhang, Yuman Li, Lei Huang, Jing Wang, Yali Yang, Qing Lv, Zhengyang Han, Mingxing Xie and Xiangming Zhu Tags: Research Source Type: research
Lonidamine liposomes to enhance photodynamic and photothermal therapy of hepatocellular carcinoma by inhibiting glycolysis
Phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has great promise in the treatment of cancer. However, there are many obstacles that can restrict the therapeutic efficacy of ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 15, 2023 Category: Nanotechnology Authors: Lei Lei, Wenbin Dai, Jiaping Man, Haitao Hu, Qiao Jin, Bo Zhang and Zhe Tang Tags: Research Source Type: research
Prostate cancer-derived small extracellular vesicle proteins: the hope in diagnosis, prognosis, and therapeutics
Current diagnostic tools for prostate cancer (PCa) diagnosis and risk stratification are insufficient. The hidden onset and poor efficacy of traditional therapies against metastatic PCa make this disease a hea... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 14, 2023 Category: Nanotechnology Authors: Haotian Chen, Bairen Pang, Cheng Zhou, Meng Han, Jie Gong, Yong Li and Junhui Jiang Tags: Review Source Type: research
Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: an up-to-date perspective
Neurons and their connecting axons gradually degenerate in neurodegenerative diseases (NDs), leading to dysfunctionality of the neuronal cells and eventually their death. Drug delivery for the treatment of eff... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 13, 2023 Category: Nanotechnology Authors: Dur E Nayab, Fakhar ud Din, Hussain Ali, Warda Arooj Kausar, Shaiza Urooj, Maryam Zafar, Ibrahim Khan, Kanwal Shabbir and Gul Majid Khan Tags: Review Source Type: research
Evidence of brain target engagement in Parkinson ’s disease and multiple sclerosis by the investigational nanomedicine, CNM-Au8, in the REPAIR phase 2 clinical trials
Impaired brain energy metabolism has been observed in many neurodegenerative diseases, including Parkinson ’s disease (PD) and multiple sclerosis (MS). In both diseases, mitochondrial dysfunction and energetic ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 13, 2023 Category: Nanotechnology Authors: Jimin Ren, Austin Rynders, Jacob Evan, Jeremy Evan, Shelia Ligozio, Karen S. Ho, Peter V. Sguigna, Robert Glanzman, Michael T. Hotchkin, Richard B. Dewey Jr. and Benjamin M. Greenberg Tags: Research Source Type: research
A novel “prime and pull” strategy mediated by the combination of two dendritic cell-targeting designs induced protective lung tissue-resident memory T cells against H1N1 influenza virus challenge
Vaccination is still the most promising strategy for combating influenza virus pandemics. However, the highly variable characteristics of influenza virus make it difficult to develop antibody-based universal v... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 13, 2023 Category: Nanotechnology Authors: Zhannan Wang, Yingkai He, Wenfeng Wang, Yawen Tian, Chongbo Ge, Futing Jia, Tongyu Zhang, Gerui Zhang, Mingyue Wang, Jinshuo Gong, Haibin Huang, Jianzhong Wang, Chunwei Shi, Wentao Yang, Xin Cao, Yan Zeng & hellip; Tags: Research Source Type: research
PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer
The present work was an endeavor to shed light on how mild photothermia possibly synergizes with immune checkpoint inhibition for tumor therapy. We established mild photothermal heating protocols to generate t... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 11, 2023 Category: Nanotechnology Authors: Chao Wang, Yong-Hong Xu, Hua-Zhen Xu, Ke Li, Quan Zhang, Lin Shi, Li Zhao and Xiao Chen Tags: Research Source Type: research
Biocompatible copper formate-based nanoparticles with strong antibacterial properties for wound healing
Copper-based antibacterial materials have emerged as a potential alternative for combating bacterial infections, which continue to pose significant health risks. Nevertheless, the use of copper-based nanoparti... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 10, 2023 Category: Nanotechnology Authors: Yue Zhou, Ping Sun, Yongbin Cao, Jiahao Yang, Qingzhi Wu and Jian Peng Tags: Research Source Type: research
Temporally and spatially resolved molecular profiling in fingerprint analysis using indium vanadate nanosheets-assisted laser desorption ionization mass spectrometry
This study presents the first-ever synthesis of samarium-doped indium vanadate nanosheets (IVONSs:Sm) via microemulsion-mediated solvothermal method. The nanosheets were subsequently utilized as a nano-matrix ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 10, 2023 Category: Nanotechnology Authors: Yanli Zhu, Jikai Wang, Chengxiao Fu, Shuangquan Liu, Pragati Awasthi, Pengfei Zeng, Danjun Chen, Yiyang Sun, Ziyi Mo and Hailing Liu Tags: Research Source Type: research
Dual peptides-modified cationic liposomes for enhanced Lung cancer gene therapy by a gap junction regulating strategy
Gene therapy for lung cancer has emerged as a novel tumor-combating strategy for its superior tumor specificity, low systematical toxicity and huge clinical translation potential. Especially, the applications ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 9, 2023 Category: Nanotechnology Authors: Ziyu Zhao, Wenhao Wang, Guanlin Wang, Zhengwei Huang, Liping Zhou, Li Lin, Yueling Ou, Wanzhen Huang, Xuejuan Zhang, Chuanbin Wu, Liang Tao and Qin Wang Tags: Research Source Type: research
Investigation of nanotopography on SOCE mediated cell migration via live-cell
This article focuses on the influence of nanotopography on the intracellular Ca2+ dynamics, the most ubiquitous ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 8, 2023 Category: Nanotechnology Authors: Yan Zhang, Kai Li, Guangwen Li, Yazheng Wang, Yide He, Wen Song and Yumei Zhang Tags: Research Source Type: research
Nanogels with covalently bound and releasable trehalose for autophagy stimulation in atherosclerosis
Atherosclerosis, cholesterol-driven plaque formation in arteries, is a complex multicellular disease which is a leading cause of vascular diseases. During the progression of atherosclerosis, the autophagic fun... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 8, 2023 Category: Nanotechnology Authors: Yuan Zhong, Ali Maruf, Kai Qu, Ma łgorzata Milewska, Ilona Wandzik, Nianlian Mou, Yu Cao and Wei Wu Tags: Research Source Type: research
Identifying tumor cell-released extracellular vesicles as biomarkers for breast cancer diagnosis by a three-dimensional hydrogel-based electrochemical immunosensor
Tumor cell-released LC3+ extracellular vesicles (LC3+ EVs) participate in immunosuppression during autophagy and contribute to the occurrence and development of breast cancer. In view of the strong association be... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 7, 2023 Category: Nanotechnology Authors: Yue Zhang, Deng Pan, Zhenqiang Ning, Fang Huang, Yiting Wei, Mingming Zhang, Yuanjian Zhang, Li-xin Wang and Yanfei Shen Tags: Research Source Type: research
Visualization of photothermal therapy by semiconducting polymer dots mediated photoacoustic detection in NIR II
Visualization of photothermal therapy mediated by photothermal transduction agents (PTAs) is important to promote individual treatment of patients with low side effects. Photoacoustic detection has emerged as ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 7, 2023 Category: Nanotechnology Authors: Xiangwei Lin, Zhourui Xu, Jiangao Li, Hongji Shi, Zhenyu Fu, Yuqing Chen, Wenguang Zhang, Yibin Zhang, Haoming Lin, Gaixia Xu, Xin Chen, Siping Chen and Mian Chen Tags: Research Source Type: research
Stem cell-derived small extracellular vesicles embedded into methacrylated hyaluronic acid wound dressings accelerate wound repair in a pressure model of diabetic ulcer
Over the past years, the development of innovative smart wound dressings is revolutionizing wound care management and research. Specifically, in the treatment of diabetic foot wounds, three-dimensional (3D) bi... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 7, 2023 Category: Nanotechnology Authors: Letizia Ferroni, Ugo D ’Amora, Chiara Gardin, Sara Leo, Luca Dalla Paola, Elena Tremoli, Alessandro Giuliani, Laura Calzà, Alfredo Ronca, Luigi Ambrosio and Barbara Zavan Tags: Research Source Type: research
