Construction of programmed time-released multifunctional hydrogel with antibacterial and anti-inflammatory properties for impaired wound healing
The successful reprogramming of impaired wound healing presents ongoing challenges due to the impaired tissue microenvironment caused by severe bacterial infection, excessive oxidative stress, as well as the i... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 23, 2024 Category: Nanotechnology Authors: Yuan Peng, Yicheng Guo, Xin Ge, Yali Gong, Yuhan Wang, Zelin Ou, Gaoxing Luo, Rixing Zhan and Yixin Zhang Tags: Research Source Type: research
A MgAl-LDH-CuS nanosheet-based thermo-responsive composite hydrogel with nir-responsive angiogenesis inhibitor releasing capability for multimode starvation therapy
The rapid proliferation of tumors is highly dependent on the nutrition supply of blood vessels. Cutting off the nutrient supply to tumors is an effective strategy for cancer treatment, known as starvation ther... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 23, 2024 Category: Nanotechnology Authors: Xueyan Liu, Tingting Hu, Yijiang Jia, Shuqing Yang, Yu Yang, Zhuolin Cui, Tao Wang, Ruizheng Liang, Chaoliang Tan and Yuji Wang Tags: Research Source Type: research
A novel microglia-targeting strategy based on nanoparticle-mediated delivery of miR-26a-5p for long-lasting analgesia in chronic pain
Accumulating evidence supports the notion that microglia play versatile roles in different chronic pain conditions. However, therapeutic strategies of chronic pain by targeting microglia remain largely overloo... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 23, 2024 Category: Nanotechnology Authors: Yitian Lu, Shuai Liu, Peng Wang, Xiangna Guo, Zaisheng Qin, Honghao Hou and Tao Tao Tags: Research Source Type: research
Carbon quantum dots of ginsenoside Rb1 for application in a mouse model of intracerebral Hemorrhage
After intracerebral hemorrhage (ICH) occurs, the overproduction of reactive oxygen species (ROS) and iron ion overload are the leading causes of secondary damage. Removing excess iron ions and ROS in the menin... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 22, 2024 Category: Nanotechnology Authors: Xiaolong Tang, Xinyu Yang, Yamei Yu, Miaojing Wu, Yuanyuan Li, Zhe Zhang, Guangyu Jia, Qi Wang, Wei Tu, Ye Wang, Xingen Zhu and Shiyong Li Tags: Research Source Type: research
ECM stiffness affects cargo sorting into MSC-EVs to regulate their secretion and uptake behaviors
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have garnered extensive attention as natural product-based nanomedicines and potential drug delivery vehicles. However, the specific mechanism for... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 21, 2024 Category: Nanotechnology Authors: Zhixiao Liu, Yingying Liu, Yu Li, Sha Xu, Yang Wang, Yuruchen Zhu, Chu Jiang, Kaizhe Wang, Yinan Zhang and Yue Wang Tags: Research Source Type: research
Bi2S3/Ti3C2-TPP nano-heterostructures induced by near-infrared for photodynamic therapy combined with photothermal therapy on hypoxic tumors
Photodynamic therapy (PDT) efficacy of bismuth sulfide (Bi2S3) semiconductor has been severely restricted by its electron –hole pairs (e−−h+) separation inefficiency and oxygen (O2) deficiency in tumors, which gre... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 20, 2024 Category: Nanotechnology Authors: Hanwen Jiang, Jingxian Sun, Fucong Liu, Yuanjiao Zhao, Xin Chen, Changsong Dai and Zhaohui Wen Tags: Research Source Type: research
Developing liver-targeted naringenin nanoparticles for breast cancer endocrine therapy by promoting estrogen metabolism
Endocrine therapy is standard for hormone receptor –positive (HR+) breast cancer treatment. However, current strategies targeting estrogen signaling pay little attention to estradiol metabolism in the liver and is... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 19, 2024 Category: Nanotechnology Authors: Yuying Zhao, Hanxu Tan, Juping Zhang, Dandan Zhan, Bowen Yang, Shicui Hong, Bo Pan, Neng Wang, Tongkai Chen, Yafei Shi and Zhiyu Wang Tags: Research Source Type: research
Design of a delivery vehicle chitosan-based self-assembling: controlled release, high hydrophobicity, and safe treatment of plant fungal diseases
Traditional pesticides are poorly water-soluble and suffer from low bioavailability. N-succinyl chitosan (NSCS) is a water-soluble chitosan derivative, has been recently used to encapsulate hydrophobic drugs to i... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 19, 2024 Category: Nanotechnology Authors: Qing Zhou, Zhi Xia, Yu Zhang, Zhiling Sun, Wei Zeng, Nian Zhang, Chunmei Yuan, Chenyu Gong, Yuanxiang Zhou and Wei Xue Tags: Research Source Type: research
Recent advances in nanomaterial-driven strategies for diagnosis and therapy of vascular anomalies
Nanotechnology has demonstrated immense potential in various fields, especially in biomedical field. Among these domains, the development of nanotechnology for diagnosing and treating vascular anomalies has ga... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 18, 2024 Category: Nanotechnology Authors: Yiming Geng, Huwei Zou, Zhaowei Li and Haiwei Wu Tags: Review Source Type: research
Asiatic acid cyclodextrin inclusion micro-cocrystal for insoluble drug delivery and acute lung injury therapy enhancement
Acute lung injury (ALI) is a fatal respiratory disease caused by overreactive immune reactions (e.g., SARS-CoV-2 infection), with a high mortality rate. Its treatment is often compromised by inefficient drug d... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 17, 2024 Category: Nanotechnology Authors: Huan Shen, Li Pan, Keke Ning, Yuefei Fang, Bahtiyor Muhitdinov, Ergang Liu and Yongzhuo Huang Tags: Research Source Type: research
scRNA-seq analysis discovered suppression of immunomodulatory dependent inflammatory response in PMBCs exposed to silver nanoparticles
The assessment of AgNPs toxicity in vitro and in vivo models are frequently conflicting and inaccurate. Nevertheless, single cell immunological responses in a heterogenous environment have received little atte... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 17, 2024 Category: Nanotechnology Authors: Haribalan Perumalsamy, Xiao Xiao, Hyun-Yi Kim and Tae-Hyun Yoon Tags: Research Source Type: research
Tetrahedral framework nucleic acids for improving wound healing
Wounds are one of the most common health issues, and the cost of wound care and healing has continued to increase over the past decade. In recent years, there has been growing interest in developing innovative... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 16, 2024 Category: Nanotechnology Authors: Wanqing Zou, Jing Lu, Luyong Zhang and Duanping Sun Tags: Review Source Type: research
Development of rice bran-derived nanoparticles with excellent anti-cancer activity and their application for peritoneal dissemination
Rice bran a by-product of the rice milling process is currently underutilized. Recent studies have shown that plant-derived nanoparticles (pdNPs) can be mass-produced at a low cost and exhibit biological and t... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 16, 2024 Category: Nanotechnology Authors: Daisuke Sasaki, Hinako Suzuki, Kosuke Kusamori, Shoko Itakura, Hiroaki Todo and Makiya Nishikawa Tags: Research Source Type: research
Nanoscale engineering of gold nanostars for enhanced photoacoustic imaging
Photoacoustic (PA) imaging is a diagnostic modality that combines the high contrast resolution of optical imaging with the high tissue penetration of ultrasound. While certain endogenous chromophores can be vi... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 16, 2024 Category: Nanotechnology Authors: Rui Zhang, Sven Thor öe-Boveleth, Dmitry N. Chigrin, Fabian Kiessling, Twan Lammers and Roger M. Pallares Tags: Research Source Type: research
Anti-inflammatory and anti-oxidative electrospun nanofiber membrane promotes diabetic wound healing via macrophage modulation
In the inflammatory milieu of diabetic chronic wounds, macrophages undergo substantial metabolic reprogramming and play a pivotal role in orchestrating immune responses. Itaconic acid, primarily synthesized by... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - March 16, 2024 Category: Nanotechnology Authors: Jibing He, Shasha Zhou, Jiaxing Wang, Binbin Sun, Dalong Ni, Jinglei Wu and Xiaochun Peng Tags: Research Source Type: research
