Biomineralized tetramethylpyrazine-loaded PCL/gelatin nanofibrous membrane promotes vascularization and bone regeneration of rat cranium defects
Conventional electrospinning produces nanofibers with smooth surfaces that limit biomineralization ability. To overcome this disadvantage, we fabricated a tetramethylpyrazine (TMP)-loaded matrix-mimicking biom... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 14, 2023 Category: Nanotechnology Authors: Xiaoyu Wu, Su Ni, Ting Dai, Jingyan Li, Fang Shao, Chun Liu, Jiafeng Wang, Shijie Fan, Yadong Tan, Linxiang Zhang, Qiting Jiang and Hongbin Zhao Tags: Research Source Type: research
A candidate nanoparticle vaccine comprised of multiple epitopes of the African swine fever virus elicits a robust immune response
The African swine fever (ASF) pandemics pose a significant threat to the global swine industry, and the development of safe and effective vaccines is a daunting but necessary challenge. The level and persisten... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 14, 2023 Category: Nanotechnology Authors: Jinxing Song, Mengxiang Wang, Lei Zhou, Panpan Tian, ZhuoYa Sun, Junru Sun, Xuannian Wang, Guoqing Zhuang, Dawei Jiang, Yanan Wu and Gaiping Zhang Tags: Research Source Type: research
Exosomal miR-146a-5p derived from human umbilical cord mesenchymal stem cells can alleviate antiphospholipid antibody-induced trophoblast injury and placental dysfunction by regulating the TRAF6/NF- κB axis
Exosomes originating from human umbilical cord mesenchymal stem cells (hucMSC-exos) have become a novel strategy for treating various diseases owing to their ability to regulate intercellular signal communicat... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 13, 2023 Category: Nanotechnology Authors: Qingfeng Lv, Yuan Wang, Wei Tian, Yuqiu Liu, Mengqi Gu, Xiaotong Jiang, Yanjun Cai, Ruiheng Huo, Yuchen Li, Lei Li and Xietong Wang Tags: Research Source Type: research
Enhancing lettuce yield via Cu/Fe-layered double hydroxide nanoparticles spraying
Layered double hydroxides (LDHs) have been widely used in the field of plant engineering, such as DNA/RNA transformation and enhancing plant disease resistance. However, few studies have examined the direct ef... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 11, 2023 Category: Nanotechnology Authors: Hongyang Wu, Xiaoyang Wan, Jiefei Niu, Huimin Xu, Yu Zhang, Xian Xue, Yang Li, Qiang Li, Tao Lu, Hongjun Yu and Weijie Jiang Tags: Research Source Type: research
The construction of elastin-like polypeptides and their applications in drug delivery system and tissue repair
Elastin-like polypeptides (ELPs) are thermally responsive biopolymers derived from natural elastin. These peptides have a low critical solution temperature phase behavior and can be used to prepare stimuli-res... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 11, 2023 Category: Nanotechnology Authors: Yingshu Guo, Shiwei Liu, Dan Jing, Nianzu Liu and Xiliang Luo Tags: Review Source Type: research
Panax notoginseng: derived exosome-like nanoparticles attenuate ischemia reperfusion injury via altering microglia polarization
Cerebral ischemia/reperfusion (CI/R) injury is a clinical conundrum during the treatment of ischemic stroke. Cell-derived exosomes (CDE) were proved to be therapeutically effective for CI/R injury. However, pr... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 10, 2023 Category: Nanotechnology Authors: Shiyi Li, Ru Zhang, Anni Wang, Yang Li, Miaomiao Zhang, Jisu Kim, Ying Zhu, Qizheng Wang, Yue Zhang, Ying Wei and Jianxin Wang Tags: Research Source Type: research
Temperature sensitive nanogel-stabilized pickering emulsion of fluoroalkane for ultrasound guiding vascular embolization therapy
Various X-ray imaging technologies like computed tomography (CT) and digital subtraction angiography (DSA) are widely used in transcatheter arterial embolization (TAE) therapy for treating hepatocellular cance... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 9, 2023 Category: Nanotechnology Authors: Ling Li, Yanyan Cao, Haining Zhang, Min Zheng, Jun Xing, Chuansheng Zheng, Yanbing Zhao and Xiangliang Yang Tags: Research Source Type: research
Advanced drug delivery and therapeutic strategies for tuberculosis treatment
Tuberculosis (TB) remains a significant global health challenge, necessitating innovative approaches for effective treatment. Conventional TB therapy encounters several limitations, including extended treatmen... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 9, 2023 Category: Nanotechnology Authors: Ayushi Nair, Alosh Greeny, Amritasree Nandan, Ranjay Kumar Sah, Anju Jose, Sathish Dyawanapelly, Vijayabhaskarreddy Junnuthula, Athira K. V. and Prashant Sadanandan Tags: Review Source Type: research
Aptamer-based self-assembled nanomicelle enables efficient and targeted drug delivery
Nucleic acid aptamer-based nanomicelles have great potential for nanomedicine and nanotechnology applications. However, amphiphilic aptamer micelles are known to be inherently unstable upon interaction with ce... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 9, 2023 Category: Nanotechnology Authors: Ganghui Chen, Dongsheng Mao, Xuan Wang, Jingqi Chen, Chao Gu, Shuqin Huang, Yu Yang, Fang Zhang and Weihong Tan Tags: Research Source Type: research
Field effect transistor based wearable biosensors for healthcare monitoring
The rapid advancement of wearable biosensors has revolutionized healthcare monitoring by screening in a non-invasive and continuous manner. Among various sensing techniques, field-effect transistor (FET)-based... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 7, 2023 Category: Nanotechnology Authors: Thi Thanh-Ha Nguyen, Cong Minh Nguyen, Minh Anh Huynh, Hoang Huy Vu, Tuan-Khoa Nguyen and Nam-Trung Nguyen Tags: Review Source Type: research
Nanocomposites based on nanoceria regulate the immune microenvironment for the treatment of polycystic ovary syndrome
The immune system is closely associated with the pathogenesis of polycystic ovary syndrome (PCOS). Macrophages are one of the important immune cell types in the ovarian proinflammatory microenvironment, and am... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 7, 2023 Category: Nanotechnology Authors: Sisi Yan, Zhipeng Gao, Jinli Ding, Suming Chen, Zehao Wang, Wenyi Jin, Bing Qu, Yi Zhang, Lian Yang, Duanying Guo, Tailang Yin, Yanbing Yang, Yan Zhang and Jing Yang Tags: Methodology Source Type: research
A potential strategy against clinical carbapenem-resistant Enterobacteriaceae: antimicrobial activity study of sweetener-decorated gold nanoparticles in vitro and in vivo
Carbapenem-resistant Enterobacteriaceae (CRE) present substantial challenges to clinical intervention, necessitating the formulation of novel antimicrobial strategies to counteract them. Nanomaterials offer a dis... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 6, 2023 Category: Nanotechnology Authors: Haifeng Liu, Zeyu Huang, Huanchang Chen, Ying Zhang, Pingting Yu, Panjie Hu, Xiaotuan Zhang, Jianming Cao and Tieli Zhou Tags: Research Source Type: research
TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer
Pancreatic cancer is a highly aggressive malignancy with limited treatment options and a poor prognosis. Trophoblast cell surface antigen 2 (TROP2), a cell surface antigen overexpressed in the tumors of more t... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 6, 2023 Category: Nanotechnology Authors: Caili Xu, Min Zhu, Qian Wang, Jiajun Cui, Yuping Huang, Xiting Huang, Jing Huang, Junwei Gai, Guanghui Li, Peng Qiao, Xian Zeng, Dianwen Ju, Yakun Wan and Xuyao Zhang Tags: Research Source Type: research
Marine biomaterials in biomedical nano/micro-systems
Marine resources in unique marine environments provide abundant, cost-effective natural biomaterials with distinct structures, compositions, and biological activities compared to terrestrial species. These mar... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 5, 2023 Category: Nanotechnology Authors: Yanan Wang, Long Chen, Yuanzheng Wang, Xinyuan Wang, Deyao Qian, Jiahui Yan, Zeyu Sun, Pengfei Cui, Liangmin Yu, Jun Wu and Zhiyu He Tags: Review Source Type: research
Probing milk extracellular vesicles for intestinal delivery of RNA therapies
Oral delivery remains unattainable for nucleic acid therapies. Many nanoparticle-based drug delivery systems have been investigated for this, but most suffer from poor gut stability, poor mucus diffusion and/o... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - November 3, 2023 Category: Nanotechnology Authors: Yunyue Zhang, Mona Belaid, Xiang Luo, Armond Daci, Rin ë Limani, Julia Mantaj, Matthias Zilbauer, Komal Nayak and Driton Vllasaliu Tags: Research Source Type: research
