Gold nanoparticles exhibit anti-osteoarthritic effects via modulating interaction of the “microbiota-gut-joint” axis
Osteoarthritis (OA) is a common degenerative joint disease that can cause severe pain, motor dysfunction, and even disability. A growing body of research indicates that gut microbiota and their associated meta... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 8, 2024 Category: Nanotechnology Authors: Zihan Deng, Chuan Yang, Tingwen Xiang, Ce Dou, Dong Sun, Qijie Dai, Zhiguo Ling, Jianzhong Xu, Fei Luo and Yueqi Chen Tags: Research Source Type: research

Anti-EGFR ScFv functionalized exosomes delivering LPCAT1 specific siRNAs for inhibition of lung cancer brain metastases
Brain metastasis (BM) is one of the leading causes of cancer-related deaths in patients with advanced non-small cell lung cancer (NSCLC). However, limited treatments are available due to the presence of the bl... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 8, 2024 Category: Nanotechnology Authors: Jun Jiang, Yuan Lu, Jie Chu, Xiao Zhang, Chao Xu, Shaojie Liu, Zhuo Wan, Jiawei Wang, Lu Zhang, Kui Liu, Zhenhua Liu, Angang Yang, Xinling Ren and Rui Zhang Tags: Research Source Type: research

Mucoadhesive, antioxidant, and lubricant catechol-functionalized poly(phosphobetaine) as biomaterial nanotherapeutics for treating ocular dryness
In this study, we in... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 8, 2024 Category: Nanotechnology Authors: Hoang Linh Bui, Yun-Han Su, Chia-Jung Yang, Chun-Jen Huang and Jui-Yang Lai Tags: Research Source Type: research

Alkylated EDTA potentiates antibacterial photodynamic activity of protoporphyrin
Antibiotic resistance has garnered significant attention due to the scarcity of new antibiotics in development. Protoporphyrin IX (PpIX)-mediated photodynamic therapy shows promise as a novel antibacterial str... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 8, 2024 Category: Nanotechnology Authors: Ying Piao, Sebastian Himbert, Zifan Li, Jun Liu, Zhihao Zhao, Huahai Yu, Shuangshuang Liu, Shiqun Shao, Michael Fefer, Maikel C. Rheinst ädter and Youqing Shen Tags: Research Source Type: research

Correction: Mesoporous silica nanoparticle-encapsulated Bifidobacterium attenuates brain A β burden and improves olfactory dysfunction of APP/PS1 mice by nasal delivery
(Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 6, 2024 Category: Nanotechnology Authors: Ni Liu, Changwen Yang, Xiaohan Liang, Kai Cao, Jun Xie, Qingming Luo and Haiming Luo Tags: Correction Source Type: research

Smart osteoclasts targeted nanomedicine based on amorphous CaCO3 for effective osteoporosis reversal
Osteoporosis is characterized by an imbalance in bone homeostasis, resulting in the excessive dissolution of bone minerals due to the acidified microenvironment mediated by overactive osteoclasts. Oroxylin A (... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 5, 2024 Category: Nanotechnology Authors: Biao Yu, Qianmin Gao, Shihao Sheng, Fengjin Zhou, Zhen Geng, Yan Wei, Hao Zhang, Yan Hu, Sicheng Wang, Jianping Huang, Mengmeng Li and Jiacan Su Tags: Research Source Type: research

Tumor microenvironment reprogramming combined with immunogenic enhancement by nanoemulsions potentiates immunotherapy
The combination of immune checkpoint inhibitors and immunogenic cell death (ICD) inducers has become a promising strategy for the treatment of various cancers. However, its efficacy remains unmet because of th... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 5, 2024 Category: Nanotechnology Authors: Wenqi Shen, Yecheng Li, Ziyi Yang, Wenjing Li, Yi Cao, Yilin Liu, Zheng Wang, Renjun Pei and Chungen Xing Tags: Research Source Type: research

Hyaluronic acid stimulation of stem cells for cardiac repair: a cell-free strategy for myocardial infarct
This study aimed to explore whether extracellular vesicles (EVs) secreted from hyaluronic acid (HA)... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 4, 2024 Category: Nanotechnology Authors: Seon-Yeong Jeong, Bong-Woo Park, Jimin Kim, Seulki Lee, Haedeun You, Joohyun Lee, Susie Lee, Jae-Hyun Park, Jinju Kim, Woosup Sim, Kiwon Ban, Joonghoon Park, Hun-Jun Park and Soo Kim Tags: Research Source Type: research

Chemically modified microRNA delivery via DNA tetrahedral frameworks for dental pulp regeneration
Dental pulp regeneration is a promising strategy for addressing tooth disorders. Incorporating this strategy involves the fundamental challenge of establishing functional vascular networks using dental pulp st... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 4, 2024 Category: Nanotechnology Authors: Xiaoling Wei, Huaxing Xu, Mengqi Zhou, Qiangqiang Zhou, Mingqiang Li and Yuehua Liu Tags: Research Source Type: research

Osteosarcoma-targeted Cu and Ce based oxide nanoplatform for NIR II fluorescence/magnetic resonance dual-mode imaging and ros cascade amplification along with immunotherapy
As the lethal bone tumor, osteosarcoma often frequently occurs in children and adolescents with locally destructive and high metastasis. Distinctive kinds of nanoplatform with high therapeutical effect and pre... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 4, 2024 Category: Nanotechnology Authors: Mo Cheng, Qingjie Kong, Qing Tian, Weiluo Cai, Chunmeng Wang, Minjia Yuan, Wenxing Wang, Peiyuan Wang and Wangjun Yan Tags: Research Source Type: research

Multifunctional fucoidan-loaded Zn-MOF-encapsulated microneedles for MRSA-infected wound healing
Infected wound healing remains a challenging task in clinical practice due to several factors: (I) drug-resistant infections caused by various pathogens, (II) persistent inflammation that hinders tissue regene... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 4, 2024 Category: Nanotechnology Authors: Zichao Jiang, Jingyi Li, Jiahao Wang, Yixiao Pan, Shuailong Liang, Yihe Hu and Long Wang Tags: Research Source Type: research

The mitochondria-targeted Kaempferol nanoparticle ameliorates severe acute pancreatitis
Kaempferol (KA), an natural antioxidant of traditional Chinese medicine (TCM), is extensively used as the primary treatment for inflammatory digestive diseases with impaired redox homeostasis. Severe acute pan... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 3, 2024 Category: Nanotechnology Authors: E Wen, Yi Cao, Shiwen He, Yuezhou Zhang, Lanlan You, Tingqiu Wang, Zhigang Wang, Jun He and Yi Feng Tags: Research Source Type: research

Intranasal delivery of phenytoin loaded layered double hydroxide nanoparticles improves therapeutic effect on epileptic seizures
Improving the efficiency of antiseizure medication entering the brain is the key to reducing its peripheral toxicity. A combination of intranasal administration and nanomedicine presents a practical approach f... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 2, 2024 Category: Nanotechnology Authors: Jingxin Zhang, Huali Zuo, Yanlu Fu, Yina Cao, Qiwei Li, Qi Zhang, Yuyi Zheng, Yi Wang, Di Wu, Weiyu Chen and Jiajia Fang Tags: Research Source Type: research

MiR26a reverses enzalutamide resistance in a bone-tumor targeted system with an enhanced effect on bone metastatic CRPC
In this study, we iden... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 2, 2024 Category: Nanotechnology Authors: Yuanyuan Wang, Jiyuan Chen, Luyao Gong, Yunxia Wang, Aino Siltari, Yan-Ru Lou, Teemu J. Murtola, Shen Gao and Yuan Gao Tags: Research Source Type: research

Collision of herbal medicine and nanotechnology: a bibliometric analysis of herbal nanoparticles from 2004 to 2023
Herbal nanoparticles are made from natural herbs/medicinal plants, their extracts, or a combination with other nanoparticle carriers. Compared to traditional herbs, herbal nanoparticles lead to improved bioava... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 1, 2024 Category: Nanotechnology Authors: Sinan Ai, Yake Li, Huijuan Zheng, Meiling Zhang, Jiayin Tao, Weijing Liu, Liang Peng, Zhen Wang and Yaoxian Wang Tags: Review Source Type: research