Inhibitory effects of the nanoscale lysate derived from xenogenic dental pulp stem cells in lung cancer models
Lung cancer is a highly prevalent malignancy and has the highest mortality rate among all tumors due to lymph node metastasis. Bone marrow and umbilical cord-derived mesenchymal stem cells (MSCs) have demonstr... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 18, 2023 Category: Nanotechnology Authors: Yan He, Ruohan Li, Wenting She, Yilong Ai, Kesheng Li, Tushar Kumeria, Ziran Jiang, Qing Shao, Chen Zou, Abdullkhaleg Ali Albashari, Xingxiang Duan and Qingsong Ye Tags: Research Source Type: research

Rational design of NIR-II molecule-engineered nanoplatform for preoperative downstaging and imaging-guided surgery of orthotopic hepatic tumor
Orthotopic advanced hepatic tumor resection without precise location and preoperative downstaging may cause clinical postoperative recurrence and metastasis. Early accurate monitoring and tumor size reduction ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 18, 2023 Category: Nanotechnology Authors: Qi Pan, Ke Li, Xueqin Kang, Kaixuan Li, Zihe Cheng, Yafei Wang, Yuye Xu, Lei Li, Na Li, Guilong Wu, Sha Yang, Shuo Qi, Guodong Chen, Xiaofeng Tan, Yonghua Zhan, Li Tang & hellip; Tags: Research Source Type: research

Reprogramming mitochondrial metabolism of macrophages by miRNA-released microporous coatings to prevent peri-implantitis
Although various new biomaterials have enriched the methods for peri-implant inflammation treatment, their efficacy is still debated, and secondary operations on the implant area have also caused pain for pati... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 17, 2023 Category: Nanotechnology Authors: Hongming Zhang, Yun Yuan, Hanxiao Xue, Runping Yu, Xiayue Jin, Xiaolin Wu and Hui Huang Tags: Research Source Type: research

Self-assembly of H2S-responsive nanoprodrugs based on natural rhein and geraniol for targeted therapy against Salmonella Typhimurium
Salmonellosis is a globally extensive food-borne disease, which threatens public health and results in huge economic losses in the world annually. The rising prevalence of antibiotic resistance in Salmonella pose... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 16, 2023 Category: Nanotechnology Authors: Lu Han, Tao Zang, Lulu Tan, Dunsheng Liang, Tengfei Long, Xuwei Liu, Xiaofan Shen, Hao Ren, ZhiPeng Li, Zhaoxiang Lu, Shengqiu Tang, Xiaoping Liao, Yahong Liu, Chaoqun Zhang and Jian Sun Tags: Research Source Type: research

Ultrasound-targeted microbubble destruction promotes PDGF-primed bone mesenchymal stem cell transplantation for myocardial protection in acute Myocardial Infarction in rats
Ultrasound-targeted microbubble destruction (UTMD) has emerged as a promising strategy for the targeted delivery of bone marrow mesenchymal stem cells (MSCs) to the ischemic myocardium. However, the limited mi... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 15, 2023 Category: Nanotechnology Authors: Zhenxing Sun, Yu Cai, Yihan Chen, Qiaofeng Jin, Ziming Zhang, Li Zhang, Yuman Li, Lei Huang, Jing Wang, Yali Yang, Qing Lv, Zhengyang Han, Mingxing Xie and Xiangming Zhu Tags: Research Source Type: research

Lonidamine liposomes to enhance photodynamic and photothermal therapy of hepatocellular carcinoma by inhibiting glycolysis
Phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has great promise in the treatment of cancer. However, there are many obstacles that can restrict the therapeutic efficacy of ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 15, 2023 Category: Nanotechnology Authors: Lei Lei, Wenbin Dai, Jiaping Man, Haitao Hu, Qiao Jin, Bo Zhang and Zhe Tang Tags: Research Source Type: research

Prostate cancer-derived small extracellular vesicle proteins: the hope in diagnosis, prognosis, and therapeutics
Current diagnostic tools for prostate cancer (PCa) diagnosis and risk stratification are insufficient. The hidden onset and poor efficacy of traditional therapies against metastatic PCa make this disease a hea... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 14, 2023 Category: Nanotechnology Authors: Haotian Chen, Bairen Pang, Cheng Zhou, Meng Han, Jie Gong, Yong Li and Junhui Jiang Tags: Review Source Type: research

Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: an up-to-date perspective
Neurons and their connecting axons gradually degenerate in neurodegenerative diseases (NDs), leading to dysfunctionality of the neuronal cells and eventually their death. Drug delivery for the treatment of eff... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 13, 2023 Category: Nanotechnology Authors: Dur E Nayab, Fakhar ud Din, Hussain Ali, Warda Arooj Kausar, Shaiza Urooj, Maryam Zafar, Ibrahim Khan, Kanwal Shabbir and Gul Majid Khan Tags: Review Source Type: research

Evidence of brain target engagement in Parkinson ’s disease and multiple sclerosis by the investigational nanomedicine, CNM-Au8, in the REPAIR phase 2 clinical trials
Impaired brain energy metabolism has been observed in many neurodegenerative diseases, including Parkinson ’s disease (PD) and multiple sclerosis (MS). In both diseases, mitochondrial dysfunction and energetic ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 13, 2023 Category: Nanotechnology Authors: Jimin Ren, Austin Rynders, Jacob Evan, Jeremy Evan, Shelia Ligozio, Karen S. Ho, Peter V. Sguigna, Robert Glanzman, Michael T. Hotchkin, Richard B. Dewey Jr. and Benjamin M. Greenberg Tags: Research Source Type: research

A novel “prime and pull” strategy mediated by the combination of two dendritic cell-targeting designs induced protective lung tissue-resident memory T cells against H1N1 influenza virus challenge
Vaccination is still the most promising strategy for combating influenza virus pandemics. However, the highly variable characteristics of influenza virus make it difficult to develop antibody-based universal v... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 13, 2023 Category: Nanotechnology Authors: Zhannan Wang, Yingkai He, Wenfeng Wang, Yawen Tian, Chongbo Ge, Futing Jia, Tongyu Zhang, Gerui Zhang, Mingyue Wang, Jinshuo Gong, Haibin Huang, Jianzhong Wang, Chunwei Shi, Wentao Yang, Xin Cao, Yan Zeng & hellip; Tags: Research Source Type: research

PD-L1 blockade TAM-dependently potentiates mild photothermal therapy against triple-negative breast cancer
The present work was an endeavor to shed light on how mild photothermia possibly synergizes with immune checkpoint inhibition for tumor therapy. We established mild photothermal heating protocols to generate t... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 11, 2023 Category: Nanotechnology Authors: Chao Wang, Yong-Hong Xu, Hua-Zhen Xu, Ke Li, Quan Zhang, Lin Shi, Li Zhao and Xiao Chen Tags: Research Source Type: research

Biocompatible copper formate-based nanoparticles with strong antibacterial properties for wound healing
Copper-based antibacterial materials have emerged as a potential alternative for combating bacterial infections, which continue to pose significant health risks. Nevertheless, the use of copper-based nanoparti... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 10, 2023 Category: Nanotechnology Authors: Yue Zhou, Ping Sun, Yongbin Cao, Jiahao Yang, Qingzhi Wu and Jian Peng Tags: Research Source Type: research

Temporally and spatially resolved molecular profiling in fingerprint analysis using indium vanadate nanosheets-assisted laser desorption ionization mass spectrometry
This study presents the first-ever synthesis of samarium-doped indium vanadate nanosheets (IVONSs:Sm) via microemulsion-mediated solvothermal method. The nanosheets were subsequently utilized as a nano-matrix ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 10, 2023 Category: Nanotechnology Authors: Yanli Zhu, Jikai Wang, Chengxiao Fu, Shuangquan Liu, Pragati Awasthi, Pengfei Zeng, Danjun Chen, Yiyang Sun, Ziyi Mo and Hailing Liu Tags: Research Source Type: research

Dual peptides-modified cationic liposomes for enhanced Lung cancer gene therapy by a gap junction regulating strategy
Gene therapy for lung cancer has emerged as a novel tumor-combating strategy for its superior tumor specificity, low systematical toxicity and huge clinical translation potential. Especially, the applications ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 9, 2023 Category: Nanotechnology Authors: Ziyu Zhao, Wenhao Wang, Guanlin Wang, Zhengwei Huang, Liping Zhou, Li Lin, Yueling Ou, Wanzhen Huang, Xuejuan Zhang, Chuanbin Wu, Liang Tao and Qin Wang Tags: Research Source Type: research

Investigation of nanotopography on SOCE mediated cell migration via live-cell
This article focuses on the influence of nanotopography on the intracellular Ca2+ dynamics, the most ubiquitous ... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - December 8, 2023 Category: Nanotechnology Authors: Yan Zhang, Kai Li, Guangwen Li, Yazheng Wang, Yide He, Wen Song and Yumei Zhang Tags: Research Source Type: research