Monocyte-to-lymphocyte ratio is associated with 28-day mortality in patients with acute respiratory distress syndrome: a retrospective study
ConclusionsHigher MLR values were associated with 28-day mortality in patients with ARDS. Further investigation is required to verify this relationship with prospectively collected data. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - August 6, 2021 Category: Intensive Care Source Type: research
A scoping review of registry captured indicators for evaluating quality of critical care in ICU
ConclusionsDespite the complexity and risk associated with ICU care, there are only a small number of operational indicators used. Future selection of QIs would benefit from a stakeholder-driven approach, whereby the values of patients and communities and the priorities for actionable improvement as perceived by healthcare providers are prioritized and include greater focus on measuring discriminable processes of care. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - August 5, 2021 Category: Intensive Care Source Type: research
Conservative oxygen therapy for critically ill patients: a meta-analysis of randomized controlled trials
ConclusionsOur findings indicate that conservative oxygen therapy strategy did not improve the prognosis of the overall ICU patients. The subgroup of ICU patients with mild to moderate hypoxemia might obtain prognosis benefit from such a strategy without affecting other critical clinical results. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - July 22, 2021 Category: Intensive Care Source Type: research
Primary success of electrical cardioversion for new-onset atrial fibrillation and its association with clinical course in non-cardiac critically ill patients: sub-analysis of a multicenter observational study
ConclusionsThe primary success rate of ECV for new-onset AF in adult non-cardiac ICU population was low, and even if it succeeded, the subsequent recurrence rate was high. Primary success of ECV did not affect the rate of mortality. Pretreatment and delivered energy were not associated with the primary success of ECV.Trial registrationUMIN clinical trial registry, the Japanese clinical trial registry (registration number:UMIN000026401, March 31, 2017). (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - July 8, 2021 Category: Intensive Care Source Type: research
Autotaxin levels in serum and bronchoalveolar lavage fluid are associated with inflammatory and fibrotic biomarkers and the clinical outcome in patients with acute respiratory distress syndrome
ConclusionThe serum ATX level is a potential prognostic biomarker in patients with ARDS. BALF ATX is associated with pulmonary biomarkers of inflammation and fibrosis, suggesting a role of ATX in the pathogenesis of ARDS. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - June 15, 2021 Category: Intensive Care Source Type: research
Association between increased mortality and bronchial fibroscopy in intensive care units and intermediate care units during COPD exacerbations: an analysis of the 2014 and 2015 National French Medical-based Information System Databases (PMSI)
ConclusionsPerforming bronchoscopy during ICU hospitalisations for severe COPD exacerbations was associated with increased mortality. This increased mortality appears to be related to a bias in patient selection with a procedure reserved for patients with the adverse course. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - June 15, 2021 Category: Intensive Care Source Type: research
Insight into the use of tympanic temperature during target temperature management in emergency and critical care: a scoping review
ConclusionsTTy was capable to track temperature changes under a variety of TTM protocols and clinical conditions in both pre-hospital and in-hospital settings. Due to the heterogeneity and paucity of comparative temperature data, future studies are needed to fully elucidate the advantages of TTy in emergency settings and its capability to track brain temperature. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - June 12, 2021 Category: Intensive Care Source Type: research
Conventional risk prediction models fail to accurately predict mortality risk among patients with coronavirus disease 2019 in intensive care units: a difficult time to assess clinical severity and quality of care
AbstractSince the start of the coronavirus disease 2019 (COVID-19) pandemic, it has remained unknown whether conventional risk prediction tools used in intensive care units are applicable to patients with COVID-19. Therefore, we assessed the performance of established risk prediction models using the Japanese Intensive Care database. Discrimination and calibration of the models were poor. Revised risk prediction models are needed to assess the clinical severity of COVID-19 patients and monitor healthcare quality in ICUs overwhelmed by patients with COVID-19. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - June 1, 2021 Category: Intensive Care Source Type: research
A novel risk score for the prediction of airway management in patients with deep neck space abscess: a multicenter retrospective cohort study
ConclusionsThe risk score may help predict a patient ’s risk of requiring airway management, thus advancing patient safety and supporting appropriate treatment. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - May 20, 2021 Category: Intensive Care Source Type: research
Premorbid β1-selective (but not non-selective) β-blocker exposure reduces intensive care unit mortality among septic patients
ConclusionPremorbid β1-selective, but not non-selective,β-blocker use was associated with improved mortality in septic patients. This finding supports the protective effect of β1-selectiveβ-blockers in septic patients. Prospective studies are needed to confirm it. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - May 13, 2021 Category: Intensive Care Source Type: research
β1-blocker in sepsis
ConclusionAccumulating evidence is supporting the use of ultrashort-acting β1-blockers while larger randomized controlled trials to clarify the effect of ultrashort-acting β1-blockers are still warranted. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - May 8, 2021 Category: Intensive Care Source Type: research
Creation of an artificial intelligence model for intubation difficulty classification by deep learning (convolutional neural network) using face images: an observational study
ConclusionThis is the first study to apply deep learning (CNN) to classify intubation difficulties using an AI model. We could create an AI model with an AUC of 0.864. Our AI model may be useful for tracheal intubation performed by inexperienced medical staff in emergency situations or under general anesthesia. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - May 6, 2021 Category: Intensive Care Source Type: research
Interleukin-9 promotes intestinal barrier injury of sepsis: a translational research
ConclusionIL-9 is closely related to intestinal mucosal barrier injury and mortality in sepsis. IL-9 blockade has the potential to improve the barrier injury in sepsis.Trial registrationThe study was registered atClinicalTrials.gov (ID: NCT03791866, Date: December 2018). (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - May 3, 2021 Category: Intensive Care Source Type: research
Cardiac biomarkers in acute respiratory distress syndrome: a systematic review and meta-analysis
ConclusionBiomarkers of cardiac stretch are associated with increased mortality in ARDS. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - April 26, 2021 Category: Intensive Care Source Type: research
A novel mouse model of heatstroke accounting for ambient temperature and relative humidity
ConclusionsWe developed a novel mouse heatstroke model that considered AT and RH. We found that ORS administration improved inadequate circulation and reduced tissue injury by increasing cotransporter gene expression in the intestines. (Source: Journal of Intensive Care)
Source: Journal of Intensive Care - April 16, 2021 Category: Intensive Care Source Type: research
