Is preoperative pancreatic juice cytology useful for determining therapeutic strategies for patients with intraductal papillary mucinous neoplasm of the pancreas?
ConclusionsPJC in IPMN is not a recommended examination because of its low overall sensitivity and no significant difference in diagnostic performance by type, location, or subclassification. Although the sensitivity is low, the positive predictive value is high, so we suggest that pancreatic juice cytology be performed only in cases where the patient is not sure about surgery. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 13, 2023 Category: Gastroenterology Authors: Rintaro Nagayama, Toshiharu Ueki, Yasuhiro Shimizu, Susumu Hijioka, Masafumi Nakamura, Masayuki Kitano, Kazuo Hara, Atsushi Masamune, Toshifumi Kin, Keiji Hanada, Shinsuke Koshita, Reiko Yamada, Mamoru Takenaka, Takao Itoi, Akio Yanagisawa, Tags: ORIGINAL ARTICLE Source Type: research

Calcium administration appears not to benefit acute pancreatitis patients with hypocalcemia
ConclusionAP patients with hypocalcemia could not benefit from calcium administration, which has no association with multiple mortality and is significantly associated with prolonged LOS in the hospital and ICU. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 7, 2023 Category: Gastroenterology Authors: Tianao Yan, Yifei Ma, Zheng Wang, Jun Lyu, Shuai Wu, Chun Zhang, Wanzhen Wei, Jiahui Zeng, Zhenhua Ma, Kedong Xu Tags: ORIGINAL ARTICLE Source Type: research

Short ‐term outcomes of pancreatoduodenectomy in older individuals over a 9‐year period using real‐world data: A multilevel analysis based on a nationwide administrative database in Japan
ConclusionsThese real-world data emphasize the higher levels of morbidity, mortality, and cost in older patients. Careful attention should be paid when considering the indication for PD in older individuals. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 1, 2023 Category: Gastroenterology Authors: Yasuhisa Mori, Makoto Okawara, Kazunori Shibao, Shiro Kohi, Toshihisa Tamura, Norihiro Sato, Yoshihisa Fujino, Kiyohide Fushimi, Shinya Matsuda, Keiji Hirata Tags: ORIGINAL ARTICLE Source Type: research

The efficacy and safety of pure laparoscopic liver resection for hepatocellular carcinoma in super ‐elderly patients over 80 years: A multicenter propensity analysis
ConclusionsLaparoscopic liver resection can be safely performed in elderly patients aged ≥80 years. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 28, 2023 Category: Gastroenterology Authors: Yosuke Namba, Tsuyoshi Kobayashi, Masakazu Hashimoto, Takashi Onoe, Hiroaki Mashima, Koichi Oishi, Naruhiko Honmyo, Tomoyuki Abe, Shintaro Kuroda, Hideki Ohdan Tags: ORIGINAL ARTICLE Source Type: research

Is the anterior approach recommended for liver resection of hepatocellular carcinoma? A systematic review and meta ‐analysis
ConclusionsThe AA for HCC liver resection helped reduce blood loss and need for transfusion, improving the DFS and OS. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 21, 2023 Category: Gastroenterology Authors: Takamichi Ishii, Kentaro Iwaki, Akiyoshi Nakakura, Yoichiro Uchida, Takashi Ito, Etsuro Hatano Tags: SYSTEMATIC REVIEW Source Type: research

SGLT2 is upregulated to acquire cisplatin resistance and SGLT2 inhibition reduces cisplatin resistance in hepatoblastoma
ConclusionsCisplatin-resistant hepatoblastoma cells exhibited upregulated SGLT2 expression and activated glucose uptake to survive under cisplatin stress. SGLT2 inhibition decreased cellular resistance to cisplatin. SGLT2 inhibition with cisplatin therapy could be a novel therapeutic strategy for cisplatin-resistant hepatoblastoma patients. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 6, 2023 Category: Gastroenterology Authors: Sunao Fujiyoshi, Shohei Honda, Momoko Ara, Takafumi Kondo, Nozomi Kobayashi, Akinobu Taketomi Tags: ORIGINAL ARTICLE Source Type: research

Potential versatile uses of a novel ultra ‐thin peroral cholangioscope
(Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 2, 2023 Category: Gastroenterology Authors: Ryosuke Tonozuka, Kazumasa Nagai, Takayoshi Tsuchiya, Reina Tanaka, Shuntaro Mukai, Kenjiro Yamamoto, Hirohito Minami, Yukitoshi Matsunami, Hiroyuki Kojima, Takao Itoi Tags: HOW I DO IT Source Type: research

Liver regeneration after hepatectomy is significantly suppressed in a muscular atrophy mouse model
ConclusionsBCAA administration may improve the suppression of liver regeneration in patients with sarcopenia. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 1, 2023 Category: Gastroenterology Authors: Kei Hagiwara, Akira Watanabe, Norifumi Harimoto, Kenichiro Araki, Takehiko Yokobori, Ryo Muranushi, Kouki Hoshino, Norihiro Ishii, Mariko Tsukagoshi, Ken Shirabe Tags: ORIGINAL ARTICLE Source Type: research

Endoscopic retrieval of a proximally migrated fully covered self ‐expandable metal stent using biopsy forceps with a guiding sheath cannula
(Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 1, 2023 Category: Gastroenterology Authors: Kenjiro Yamamoto, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Shuntaro Mukai, Kazumasa Nagai, Yukitoshi Matsunami, Hiroyuki Kojima, Hirohito Minami, Takao Itoi Tags: HOW I DO IT Source Type: research

Early and late effects of endoscopic interventions in patients with malignant afferent loop syndrome: A single ‐center experience and literature review
ConclusionsEach of the available endoscopic interventions for malignant ALS can be expected to produce similar outcomes, including duration of stent patency. The choice of endoscopic intervention should be made based on the characteristics of each treatment. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 1, 2023 Category: Gastroenterology Authors: Kenjiro Yamamoto, Takao Itoi, Yukitoshi Matsunami, Atsushi Sofuni, Takayoshi Tsuchiya, Shuntaro Mukai, Hiroyuki Kojima, Hirohito Minami, Ryosuke Nakatsubo, Ryosuke Tonozuka Tags: ORIGINAL ARTICLE Source Type: research

Novel peroral cholangioscopy ‐guided electrohydraulic lithotripsy for difficult stones
(Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - October 28, 2023 Category: Gastroenterology Authors: Haruo Miwa, Kazuya Sugimori, Hayato Yoshimura, Kazuki Endo, Ritsuko Oishi, Akihiro Funaoka, Hiromi Tsuchiya, Takashi Kaneko, Kazushi Numata, Shin Maeda Tags: HOW I DO IT Source Type: research

RAS mutation status in combination with the JSHBPS nomogram may be useful for preoperative identification of colorectal liver metastases with high risk of recurrence and mortality after hepatectomy
ConclusionRAS mutation status in combination with the JSHBPS nomogram may be useful for preoperatively identifying CRLM with high risk of recurrence and mortality after hepatectomy. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - October 28, 2023 Category: Gastroenterology Authors: Toru Takematsu, Kosuke Mima, Hiromitsu Hayashi, Yuki Kitano, Shigeki Nakagawa, Yukiharu Hiyoshi, Hirohisa Okabe, Katsunori Imai, Yuji Miyamoto, Hideo Baba Tags: ORIGINAL ARTICLE Source Type: research

A multi ‐institutional study designed by members of Tokyo Guidelines (TG) Core Meeting to elucidate the clinical characteristics and pathogenesis of acute cholangitis after bilioenteric anastomosis and biliary stent insertion with a focus on biliary obstruction: Role of transient hepatic attenuation diffe rence (THAD) and pneumobilia in improving TG diagnostic performance
ConclusionsThe diagnostic rate of PBR-AC using TG18 is low, but adding THAD and pneumobilia to TG imaging criteria may improve TG diagnostic performance. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - October 27, 2023 Category: Gastroenterology Authors: Hiroyuki Kato, Tadahiro Takada, Steven Strasberg, Shuji Isaji, Keiji Sano, Masahiro Yoshida, Takao Itoi, Kohji Okamoto, Seiki Kiriyama, Shintaro Yagi, Takashi Matsubara, Ryota Higuchi, Tetsuji Ohyama, Takeyuki Misawa, Shuntaro Mukai, Yasuhi Tags: ORIGINAL ARTICLE Source Type: research

LncRNA –mRNA coexpression analysis reveals distinct pathogenic mechanisms for subtypes of congenital biliary dilatation
ConclusionOur study suggests that lncRNAs may modulate pancreaticobiliary duct development differently in cystic and fusiform CBD, providing new insights for etiology studies and clinical treatment. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - October 26, 2023 Category: Gastroenterology Authors: Chengbo Ai, Xiaolong Xie, Yong Lv, Qianwen Zheng, Jiayin Yang, Bo Xiang, Jing Chen Tags: ORIGINAL ARTICLE Source Type: research

Reappraisal of surgical and survival outcomes of 500 consecutive cases of robotic pancreaticoduodenectomy
ConclusionsReappraisal of this study has confirmed that RPD is not only technically feasible without increasing surgical risks but also oncologically justified without compromising survival outcomes for both pancreatic head and other periampullary cancers over time. Moreover, RPD is associated with the benefits of low surgical mortality, blood loss, and delayed gastric emptying. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - October 26, 2023 Category: Gastroenterology Authors: Bor ‐Shiuan Shyr, Yi‐Ming Shyr, Shih‐Chin Chen, Shin‐E Wang, Bor‐Uei Shyr Tags: ORIGINAL ARTICLE Source Type: research