Long ‐term outcomes of neoadjuvant gemcitabine, nab‐paclitaxel, and S1 (GAS) in borderline resectable pancreatic cancer with arterial contact: Results from a phase II trial
ConclusionsThis long-term evaluation of the neoadjuvant GAS trial demonstrated the high efficacy of the regimen, suggesting that it is a promising treatment option for patients with BRPC-A. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 30, 2023 Category: Gastroenterology Authors: Kenichiro Uemura, Naru Kondo, Takeshi Sudo, Tatsuaki Sumiyoshi, Ryuta Shintakuya, Kenjiro Okada, Kenta Baba, Takumi Harada, Yoshiaki Murakami, Shinya Takahashi Tags: ORIGINAL ARTICLE Source Type: research

Current status and therapeutic strategy of acute acalculous cholecystitis: Japanese nationwide survey in the era of the Tokyo guidelines
ConclusionsThe proportions of severity grade and mortality of acute acalculous cholecystitis were found to be similar to those of acute cholecystitis, and laparoscopic cholecystectomy is recommended as an effective treatment option. (UMIN000047631). (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 28, 2023 Category: Gastroenterology Authors: Takanori Morikawa, Masanori Akada, Kenji Shimizu, Yasunori Nishida, Junko Izai, Hiroki Kajioka, Takayuki Miura, Masaharu Ishida, Michiaki Unno Tags: ORIGINAL ARTICLE Source Type: research

Questionnaire survey of Japanese board ‐certified expert hepatobiliary and pancreatic surgeons and instructors on the surgical indications for hepatocellular carcinoma
ConclusionsThe current views of Japanese expert surgeons on the resectability criteria for HCC were clarified for the first time. The findings could serve as a basis for preparing expert consensus statements on the resectability criteria for HCC. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 27, 2023 Category: Gastroenterology Authors: Keiichi Akahoshi, Junichi Shindoh, Minoru Tanabe, Shuichi Watanabe, Hayato Takamizawa, Susumu Eguchi, Iraru Endo, Shoji Kubo, Akinobu Taketomi, Hiroaki Nagano, Masafumi Nakamura, Kiyoshi Hasegawa, Etsuro Hatano, Tomoharu Yoshizumi, Norihiro Tags: ORIGINAL ARTICLE Source Type: research

Comparison of postoperative outcomes in cases achieving sustained virological response with direct ‐acting antiviral and interferon therapy
ConclusionsThere was no significant difference in OS and recurrence-free survival (RFS) between the preoperative SVR achieved with DAA and IFN groups in this study, although liver function was significantly worse at the time of surgery in the DAA group compared to the IFN group. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 23, 2023 Category: Gastroenterology Authors: Masakazu Hashimoto, Tsuyoshi Kobayashi, Masahiro Ohira, Sho Okimoto, Tomoyuki Abe, Masashi Inoue, Takashi Onoe, Naruhiko Honmyo, Shintaro Kuroda, Hideki Ohdan Tags: ORIGINAL ARTICLE Source Type: research

The role of adjuvant chemotherapy in management of stage I pancreatic ductal adenocarcinoma deserves independent high quality research
(Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 22, 2023 Category: Gastroenterology Authors: Shahin Hajibandeh, Shahab Hajibandeh, Tejinderjit S. Athwal Tags: LETTER TO THE EDITOR Source Type: research

Proper access route selection using the low echo reduction function during endoscopic ultrasound ‐guided biliary drainage (with video)
(Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 21, 2023 Category: Gastroenterology Authors: Takeshi Ogura, Taro Iwatsubo, Kimi Bessho, Nobuhiro Hattori, Hiroki Nishikawa Tags: HOW I DO IT Source Type: research

IgG4 ‐related pancreatobiliary diseases could be associated with onset of pancreatobiliary cancer: A multicenter cohort study
ConclusionsPatients with autoimmune pancreatitis and IgG4-SC were associated with a high risk of pancreatic and bile duct cancer. Patients with AIP and IgG4-SC have a worse prognosis when they develop pancreatobiliary cancer. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 21, 2023 Category: Gastroenterology Authors: Yusuke Kurita, Kensuke Kubota, Yuji Fujita, Seitaro Tsujino, Yusuke Sekino, Noriki Kasuga, Akito Iwasaki, Mai Iwase, Takeshi Izuka, Koichi Kagawa, Emiko Tanida, Shin Yagi, Sho Hasegawa, Takamitsu Sato, Kunihiro Hosono, Noritoshi Kobayashi, Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
(Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 14, 2023 Category: Gastroenterology Tags: ISSUE INFORMATION Source Type: research

Is preoperative pancreatic juice cytology useful for determining therapeutic strategies for patients with intraductal papillary mucinous neoplasm of the pancreas?
ConclusionsPJC in IPMN is not a recommended examination because of its low overall sensitivity and no significant difference in diagnostic performance by type, location, or subclassification. Although the sensitivity is low, the positive predictive value is high, so we suggest that pancreatic juice cytology be performed only in cases where the patient is not sure about surgery. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 13, 2023 Category: Gastroenterology Authors: Rintaro Nagayama, Toshiharu Ueki, Yasuhiro Shimizu, Susumu Hijioka, Masafumi Nakamura, Masayuki Kitano, Kazuo Hara, Atsushi Masamune, Toshifumi Kin, Keiji Hanada, Shinsuke Koshita, Reiko Yamada, Mamoru Takenaka, Takao Itoi, Akio Yanagisawa, Tags: ORIGINAL ARTICLE Source Type: research

Calcium administration appears not to benefit acute pancreatitis patients with hypocalcemia
ConclusionAP patients with hypocalcemia could not benefit from calcium administration, which has no association with multiple mortality and is significantly associated with prolonged LOS in the hospital and ICU. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 7, 2023 Category: Gastroenterology Authors: Tianao Yan, Yifei Ma, Zheng Wang, Jun Lyu, Shuai Wu, Chun Zhang, Wanzhen Wei, Jiahui Zeng, Zhenhua Ma, Kedong Xu Tags: ORIGINAL ARTICLE Source Type: research

Short ‐term outcomes of pancreatoduodenectomy in older individuals over a 9‐year period using real‐world data: A multilevel analysis based on a nationwide administrative database in Japan
ConclusionsThese real-world data emphasize the higher levels of morbidity, mortality, and cost in older patients. Careful attention should be paid when considering the indication for PD in older individuals. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - December 1, 2023 Category: Gastroenterology Authors: Yasuhisa Mori, Makoto Okawara, Kazunori Shibao, Shiro Kohi, Toshihisa Tamura, Norihiro Sato, Yoshihisa Fujino, Kiyohide Fushimi, Shinya Matsuda, Keiji Hirata Tags: ORIGINAL ARTICLE Source Type: research

The efficacy and safety of pure laparoscopic liver resection for hepatocellular carcinoma in super ‐elderly patients over 80 years: A multicenter propensity analysis
ConclusionsLaparoscopic liver resection can be safely performed in elderly patients aged ≥80 years. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 28, 2023 Category: Gastroenterology Authors: Yosuke Namba, Tsuyoshi Kobayashi, Masakazu Hashimoto, Takashi Onoe, Hiroaki Mashima, Koichi Oishi, Naruhiko Honmyo, Tomoyuki Abe, Shintaro Kuroda, Hideki Ohdan Tags: ORIGINAL ARTICLE Source Type: research

Is the anterior approach recommended for liver resection of hepatocellular carcinoma? A systematic review and meta ‐analysis
ConclusionsThe AA for HCC liver resection helped reduce blood loss and need for transfusion, improving the DFS and OS. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 21, 2023 Category: Gastroenterology Authors: Takamichi Ishii, Kentaro Iwaki, Akiyoshi Nakakura, Yoichiro Uchida, Takashi Ito, Etsuro Hatano Tags: SYSTEMATIC REVIEW Source Type: research

SGLT2 is upregulated to acquire cisplatin resistance and SGLT2 inhibition reduces cisplatin resistance in hepatoblastoma
ConclusionsCisplatin-resistant hepatoblastoma cells exhibited upregulated SGLT2 expression and activated glucose uptake to survive under cisplatin stress. SGLT2 inhibition decreased cellular resistance to cisplatin. SGLT2 inhibition with cisplatin therapy could be a novel therapeutic strategy for cisplatin-resistant hepatoblastoma patients. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 6, 2023 Category: Gastroenterology Authors: Sunao Fujiyoshi, Shohei Honda, Momoko Ara, Takafumi Kondo, Nozomi Kobayashi, Akinobu Taketomi Tags: ORIGINAL ARTICLE Source Type: research

Potential versatile uses of a novel ultra ‐thin peroral cholangioscope
(Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - November 2, 2023 Category: Gastroenterology Authors: Ryosuke Tonozuka, Kazumasa Nagai, Takayoshi Tsuchiya, Reina Tanaka, Shuntaro Mukai, Kenjiro Yamamoto, Hirohito Minami, Yukitoshi Matsunami, Hiroyuki Kojima, Takao Itoi Tags: HOW I DO IT Source Type: research