Efficacy and Safety of Ixekizumab in Patients with Active Psoriatic Arthritis: 52-week Results from a Phase III Study (SPIRIT-P1).
CONCLUSION: During the extension period, IXEQ4W or IXEQ2W treatment demonstrated sustained efficacy in key PsA domains with a safety profile consistent with other studies investigating IXE. Clinical trial number: NCT01695239; EudraCT 2011-002326-49. PMID: 29247148 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2017 Category: Rheumatology Authors: van der Heijde D, Gladman DD, Kishimoto M, Okada M, Rathmann SS, Moriarty SR, Shuler CL, Carlier H, Benichou O, Mease PJ Tags: J Rheumatol Source Type: research

Two-year Efficacy and Safety of Subcutaneous Tocilizumab in Combination with Disease-modifying Antirheumatic Drugs Including Escalation to Weekly Dosing in Rheumatoid Arthritis.
CONCLUSION: Efficacy and safety of TCZ-SC q2w was maintained up to 2 years and remained comparable with previously published data for intravenous TCZ. Dose escalation to weekly TCZ-SC was associated with ACR responses in prior nonresponders and was well tolerated. PMID: 29247149 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2017 Category: Rheumatology Authors: Kivitz A, Olech E, Borofsky MA, Zazueta B, Navarro-Sarabia F, Radominski SC, Merrill JT, Pacheco-Tena C, Pei J, Nasmyth-Miller C, Pope JE Tags: J Rheumatol Source Type: research

Adiposity in Juvenile Psoriatic Arthritis.
CONCLUSION: In this registry, almost 1 in 5 patients with JPsA were obese and more than one-third were overweight. This is significantly more than expected compared to the US pediatric population, and appropriate longterm followup of this JPsA subgroup is warranted. PMID: 29247150 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2017 Category: Rheumatology Authors: Samad A, Stoll ML, Lavi I, Hsu JJ, Strand V, Robinson TN, Mellins ED, Zisman D, for the CARRA Legacy Registry Investigators Tags: J Rheumatol Source Type: research

The Rising Incidence of Gout and the Increasing Burden of Comorbidities: A Population-based Study over 20 Years.
CONCLUSION: The incidence of gout has more than doubled over the recent 20 years. This increase together with the more frequent occurrence of comorbid conditions and cardiovascular risk factors represents a significant public health challenge. PMID: 29247151 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2017 Category: Rheumatology Authors: Elfishawi MM, Zleik N, Kvrgic Z, Michet CJ, Crowson CS, Matteson EL, Bongartz T Tags: J Rheumatol Source Type: research

Prevalence of Comorbidities and Risk Factors for Comorbidities in Patients with Spondyloarthritis in Latin America: A Comparative Study with the General Population and Data from the ASAS-COMOSPA Study.
CONCLUSION: Patients with SpA in LA are at increased risk of AHT and TB in comparison to the general population. While this sample of patients may not be entirely representative of the patient population in each country, a systematic evaluation of these comorbidities in all patients with SpA still may help to monitor these conditions better. PMID: 29247152 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2017 Category: Rheumatology Authors: Bautista-Molano W, Landewé R, Burgos-Vargas R, Maldonado-Cocco J, Moltó A, van den Bosch F, Valle-Oñate R, Dougados M, van der Heijde D Tags: J Rheumatol Source Type: research

The Use of the OMERACT Ultrasound Tenosynovitis Scoring System in Multicenter Clinical Trials.
ch F, Terslev L Abstract OBJECTIVE: To test the sensitivity to change of the Outcome Measures in Rheumatology Clinical Trials (OMERACT) ultrasound (US) scoring system for tenosynovitis when applied in a multicenter design. METHODS: RA patients with US-verified tenosynovitis were recruited when scheduled for treatment intensification. Tenosynovitis was assessed at baseline, and 3 and 6 months followup, using the semiquantitative OMERACT scoring system. RESULTS: Expressed in median (25th; 75th percentiles), the overall greyscale and Doppler score decreased significantly from baseline at 4 (2; 7) and 3 (2; ...
Source: J Rheumatol - December 15, 2017 Category: Rheumatology Authors: Ammitzbøll-Danielsen M, Østergaard M, Naredo E, Iagnocco A, Möller I, D'Agostino MA, Gandjbakhch F, Terslev L Tags: J Rheumatol Source Type: research

Safety and Efficacy of Golimumab Administered Intravenously in Adults with Ankylosing Spondylitis: Results through Week 28 of the GO-ALIVE Study.
Abstract OBJECTIVE: To evaluate the safety and efficacy of intravenous golimumab (GOL) in patients with active ankylosing spondylitis (AS). METHODS: In a phase III, randomized, double-blind, placebo (PBO)-controlled trial, 208 patients were randomized (1:1) to intravenous (IV) infusions of GOL 2 mg/kg (n = 105) at weeks 0, 4, 12, and every 8 weeks, or PBO (n = 103) at weeks 0, 4, and 12, with crossover to GOL at Week 16. The primary endpoint was ≥ 20% improvement from baseline in the Assessment of Spondyloarthritis International Society Criteria (ASAS20) at Week 16. Secondary endpoints included ASAS40, &ge...
Source: J Rheumatol - December 15, 2017 Category: Rheumatology Authors: Deodhar A, Reveille JD, Harrison DD, Kim L, Lo KH, Leu JH, Hsia EC Tags: J Rheumatol Source Type: research

CXCL10 and TRAIL Are Upregulated by TXNDC5 in Rheumatoid Arthritis Fibroblast-like Synoviocytes.
CONCLUSION: Downregulation of TXNDC5 could contribute to RASF antiangiogenic and proapoptotic features through the suppression of CXCL10 and TRAIL (tumor necrosis factor-related apoptosis-inducing ligand). PMID: 29247155 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2017 Category: Rheumatology Authors: Xu B, Li J, Wu C, Liu C, Yan X, Chang X Tags: J Rheumatol Source Type: research

The Challenges of Measuring Adherence to Clinical Treatment Recommendations in Spondyloarthritis.
PMID: 28966168 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Rohekar S Tags: J Rheumatol Source Type: research

Burned to the Bone.
PMID: 28966169 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Bohm-Sigrand A, Pottecher P, Ornetti P Tags: J Rheumatol Source Type: research

IgG4-related Pericoronary Arteritis.
PMID: 28966170 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Rokutanda R, Nishihata Y, Okada M Tags: J Rheumatol Source Type: research

Introduction.
PMID: 28966171 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Tugwell P, Grosskleg S, Shea B, Beaton D, Wells GA Tags: J Rheumatol Source Type: research

What is the Definition of the Anticytoplasmic Autoantibody?
PMID: 28966172 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Chen Y, Liu J Tags: J Rheumatol Source Type: research

Anti-tRNA Synthetase-specific Immunofluorescence Patterns are Easily Detected in the Suitable Substrate.
PMID: 28966173 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Jearn LH, Kim TY Tags: J Rheumatol Source Type: research

Drs. Aggarwal and Oddis reply.
PMID: 28966174 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Aggarwal R, Oddis CV Tags: J Rheumatol Source Type: research

Large-vessel Involvement and Varicella Zoster Virus Vasculopathy in Giant Cell Arteritis-related Stroke: Something to Keep an Eye On.
PMID: 28966175 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Vitiello G, Cammelli D Tags: J Rheumatol Source Type: research

Drs. de Boysson and Aouba reply.
PMID: 28966176 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: DE Boysson H, Aouba A Tags: J Rheumatol Source Type: research

Novel Composite Radiographic Score for Longitudinal Observational Studies of Psoriatic Arthritis: A Proof-of-concept Study.
Authors: PMID: 28966177 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Tags: J Rheumatol Source Type: research

Development of a Canadian Core Clinical Dataset to Support High-quality Care for Canadian Patients with Rheumatoid Arthritis.
CONCLUSION: The CAN-RACCD stands as a national recommendation on which data elements should be routinely collected in clinical practice to monitor and support high-quality RA care. PMID: 28966205 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Barber CEH, Mosher DP, Ahluwalia V, Zummer M, Marshall DA, Choquette D, Lacaille D, Bombardier C, Lyddiatt A, Chandran V, Khodyakov D, Dao E, Barnabe C, for the RACCD Working Group Tags: J Rheumatol Source Type: research

Thoracic Syndesmophytes Commonly Occur in the Absence of Lumbar Syndesmophytes in Ankylosing Spondylitis: A Computed Tomography Study.
CONCLUSION: Syndesmophytes predominate in the thoracic spine. Lumbar radiographs underestimate the degree of thoracic involvement. PMID: 28966206 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Tan S, Yao L, Ward MM Tags: J Rheumatol Source Type: research

The Fascinating Paradox of Osteoporosis in Axial Spondyloarthropathy.
This article provides a comprehensive review of the current knowledge regarding low BMD in axSpA. It highlights our current BMD measurement techniques along with their potential pitfalls, and discusses the significance of BMD in vertebral fractures. It also identifies gaps in our knowledge and makes recommendations for future research. PMID: 28966207 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Fitzgerald GE, O'Shea FD Tags: J Rheumatol Source Type: research

Development and Validation of MRI Sacroiliac Joint Scoring Methods for the Semiaxial Scan Plane Corresponding to the Berlin and SPARCC MRI Scoring Methods, and of a New Global MRI Sacroiliac Joint Method.
CONCLUSION: Detection of SIJ BME in the semiaxial scan plane is feasible and reproducible. However, a slightly lower reliability of all 3 semiaxial methods supports the general practice of using the coronal scan-plane in therapeutic studies. PMID: 28966208 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Hededal P, Østergaard M, Sørensen IJ, Loft AG, Hindrup JS, Thamsborg G, Asmussen K, Hendricks O, Nørregaard J, Møller JM, Jurik AG, Morsel L, Balding L, Pedersen SJ Tags: J Rheumatol Source Type: research

Rebound in Measures of Disease Activity and Symptoms in Corrona Registry Patients with Psoriatic Arthritis Who Discontinue Tumor Necrosis Factor Inhibitor Therapy after Achieving Low Disease Activity.
CONCLUSION: Rebound occurred frequently in patients with PsA after TNFi discontinuation. TNFi discontinuation after achieving LDA should be carefully considered. PMID: 28966209 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Harrold LR, Stolshek BS, Rebello S, Collier DH, Mutebi A, Wade SW, Malley W, Greenberg JD, Etzel CJ Tags: J Rheumatol Source Type: research

Polypharmacy and Unplanned Hospitalizations in Patients with Rheumatoid Arthritis.
CONCLUSION: PP is common in RA and is a prognostic marker associated with increased risk of acute hospitalizations. Our data suggest that PP may be an indicator of comorbidity burden rather than a contributing cause of a drug-related toxicity. PP should be monitored to minimize inappropriate combination of prescribed medications. PP may be a useful predictor of clinical outcomes in epidemiologic studies. PMID: 28966210 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Filkova M, Carvalho J, Norton S, Scott D, Mant T, Molokhia M, Cope A, Galloway J Tags: J Rheumatol Source Type: research

Initial Serological Response after Prime-boost Pneumococcal Vaccination in Rheumatoid Arthritis Patients: Results of a Randomized Controlled Trial.
CONCLUSION: The early serological response to prime-boost vaccination with PCV13 followed by PPV23 was very similar among participants receiving bDMARD and csDMARD. However, notable differences in response were observed according to individual bDMARD. It is important to consider the RA treatment when planning pneumococcal vaccination in patients with RA. PMID: 28966211 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - October 1, 2017 Category: Rheumatology Authors: Nguyen MTT, Lindegaard H, Hendricks O, Jørgensen CS, Kantsø B, Friis-Møller N Tags: J Rheumatol Source Type: research

Trends in Treatment, Outcomes, and Incidence of Orthopedic Surgery in Patients with Rheumatoid Arthritis: An Observational Cohort Study Using the Japanese National Database of Rheumatic Diseases.
In this study, we investigated the changes in clinical outcome, treatment, and incidence of orthopedic surgery in patients with rheumatoid arthritis (RA) from 2004 to 2014. METHODS: Data were studied from the Japanese nationwide cohort database, NinJa (National Database of Rheumatic Diseases by iR-net in Japan), from 2004 to 2014. The time trends in the incidence of orthopedic procedures were analyzed using linear regression analysis. The cross-sectional annual data were compared between 2004 and 2014 to analyze the changes in clinical outcome and treatment. RESULTS: The incidence of orthopedic surgeries in patie...
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Matsumoto T, Nishino J, Izawa N, Naito M, Hirose J, Tanaka S, Yasui T, Saisho K, Tohma S Tags: J Rheumatol Source Type: research

Closing the Serological Gap in the Antiphospholipid Syndrome: The Value of "Non-criteria" Antiphospholipid Antibodies.
CONCLUSION: Failure to diagnose APS can result in severe clinical consequences. Patients displaying clinical features of APS, but negative for conventional criteria markers, should undergo additional testing for non-criteria biomarkers. In our cohort, around one-third of SN-APS patients showed reactivity to 1 or more non-criteria markers. An update to the current classification criteria incorporating new serological markers should be considered to identify and stratify patients with APS for more effective treatment and management. PMID: 28864642 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Zohoury N, Bertolaccini ML, Rodriguez-Garcia JL, Shums Z, Ateka-Barrutia O, Sorice M, Norman GL, Khamashta M Tags: J Rheumatol Source Type: research

Performance of Screening Tests for Cognitive Impairment in Systemic Lupus Erythematosus.
CONCLUSION: CI is highly prevalent and MoCA may be a useful tool to screen for CI in SLE. Patients with more years of education were less likely to have CI. PMID: 28864643 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Nantes SG, Su J, Dhaliwal A, Colosimo K, Touma Z Tags: J Rheumatol Source Type: research

Myositis-associated Interstitial Lung Disease: Predictors of Failure of Conventional Treatment and Response to Tacrolimus in a US Cohort.
Abstract OBJECTIVE: Patients with myositis-associated interstitial lung disease (MA-ILD) are often refractory to conventional treatment, and predicting their response to therapy is challenging. Recent case reports and small series suggest that tacrolimus may be useful in refractory cases. METHODS: A retrospective cohort study of patients with MA-ILD comparing clinical characteristics between those who responded to or failed conventional treatment. In those who failed conventional treatment and received adjunctive tacrolimus, response to tacrolimus was measured by the improvement in myositis, ILD, and change i...
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Sharma N, Putman MS, Vij R, Strek ME, Dua A Tags: J Rheumatol Source Type: research

Risk of Retinal Toxicity in Longterm Users of Hydroxychloroquine.
Abstract OBJECTIVE: Several studies have reported risk factors for hydroxychloroquine (HCQ) retinal toxicity, but data are limited for patients of Asian ancestry. The aim of this study was to investigate the rate of and factors for HCQ retinal toxicity in the Korean population. METHODS: There were 123 patients enrolled in this study who were using or had used HCQ. Retinal toxicity was detected using spectral domain optical coherence tomography, fundus autofluorescence, multifocal electroretinography, and automated visual field testing. Binary logistic regression analysis was performed to identify factors asso...
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Kim JW, Kim YY, Lee H, Park SH, Kim SK, Choe JY Tags: J Rheumatol Source Type: research

Development of a Core Set of Outcome Measures for Large-vessel Vasculitis: Report from OMERACT 2016.
CONCLUSION: Initial data from a clinician Delphi exercise and structured patient interviews have provided themes toward an OMERACT-endorsed core set of domains and outcome measures. PMID: 28864646 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Sreih AG, Alibaz-Oner F, Kermani TA, Aydin SZ, Cronholm PF, Davis T, Easley E, Gul A, Mahr A, McAlear CA, Milman N, Robson JC, Tomasson G, Direskeneli H, Merkel PA Tags: J Rheumatol Source Type: research

Isolated Arthritis of the Temporomandibular Joint as the Initial Manifestation of Juvenile Idiopathic Arthritis.
CONCLUSION: JIA TMJ arthritis can occur in isolation, and is probably underdiagnosed. Care providers including dentists and orthodontists should be aware of this presentation. PMID: 28864647 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Hügle B, Spiegel L, Hotte J, Wiens S, Herlin T, Cron RQ, Stoll ML, Vinod S, Stoustrup P, Pedersen TK, Twilt M Tags: J Rheumatol Source Type: research

Assessment of Disease Activity in Large-vessel Vasculitis: Results of an International Delphi Exercise.
CONCLUSION: This study highlights similarities and differences in experts' perspectives for assessing clinical activity in LVV and may guide a consensus-driven core set of validated outcomes. PMID: 28864648 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Aydin SZ, Direskeneli H, Merkel PA, International Delphi on Disease Activity Assessment in Large-vessel Vasculitis Tags: J Rheumatol Source Type: research

Phenotypic Features and Longterm Outcomes of Pediatric Inflammatory Bowel Disease Patients with Arthritis and Arthralgia.
Abstract OBJECTIVE: The natural history of pediatric inflammatory bowel disease (IBD) patients with joint involvement has not been clearly described. Thus, we aimed to investigate phenotypic features and clinical outcomes of this distinct association. METHODS: The medical records of patients with pediatric IBD diagnosed from 2000 to 2016 were reviewed retrospectively. Main outcome measures included time to first flare, hospitalization, surgery, and biologic therapy. RESULTS: Of 301 patients with Crohn disease (median age 14.2 yrs), 37 (12.3%) had arthritis while 44 (14.6%) had arthralgia at diagnosis. Ar...
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Nir O, Rinawi F, Amarilyo G, Harel L, Shamir R, Assa A Tags: J Rheumatol Source Type: research

OMERACT Endorsement of Patient-reported Outcome Instruments in Antineutrophil Cytoplasmic Antibody-associated Vasculitis.
CONCLUSION: The OMERACT Vasculitis Working Group gained endorsement by OMERACT for use of the PROMIS and the AAV-PRO in clinical trials of vasculitis. These instruments are complementary to each other. The PROMIS and the AAV-PRO need further work to assess their utility in longitudinal settings, including their ability to discriminate between treatments of varying efficacy in the setting of a randomized controlled trial. PMID: 28864650 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Robson JC, Tomasson G, Milman N, Ashdown S, Boonen A, Casey GC, Cronholm PF, Cuthbertson D, Dawson J, Direskeneli H, Easley E, Kermani TA, Farrar JT, Gebhart D, Lanier G, Luqmani RA, Mahr A, McAlear CA, Peck J, Shea B, Shea JA, Sreih AG, Tugwell PS, Merke Tags: J Rheumatol Source Type: research

Associations Between Knee Effusion-synovitis and Joint Structural Changes in Patients with Knee Osteoarthritis.
Abstract OBJECTIVE: To describe the associations between effusion-synovitis and joint structural abnormalities in patients with knee osteoarthritis (OA) over 24 months. METHODS: A posthoc analysis using data from a randomized controlled trial in 413 patients with symptomatic OA (aged 63 ± 7 yrs, 208 women). Knee effusion-synovitis volume and score, cartilage defects, cartilage volume, and bone marrow lesions (BML) were assessed using magnetic resonance imaging. Joint space narrowing (JSN) and osteophytes were assessed using radiograph. Least significant change criterion was used to define change in eff...
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Wang X, Jin X, Blizzard L, Antony B, Han W, Zhu Z, Cicuttini F, Wluka AE, Winzenberg T, Jones G, Ding C Tags: J Rheumatol Source Type: research

Spondyloarthritis: Harlequin or Chameleon?
PMID: 28864662 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Wendling D, Prati C Tags: J Rheumatol Source Type: research

Cardiovascular Morbidity in Psoriatic Arthritis: What Is the Effect of Inflammation?
PMID: 28864663 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Eder L, Harvey P Tags: J Rheumatol Source Type: research

Psoriatic Disease 10 Years Later.
PMID: 28864664 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Scarpa R, Caso F, Costa L, Peluso R, Del Puente A, Olivieri I Tags: J Rheumatol Source Type: research

The Clinical and Research Implications of Anti-carbamylated Protein Antibodies.
PMID: 28864665 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Demoruelle MK Tags: J Rheumatol Source Type: research

Lytic Bone Lesions: Osteomyelitis or Intraosseous Gout?
PMID: 28864666 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: An JW, Troster SM Tags: J Rheumatol Source Type: research

Tongue Involvement in Parry-Romberg Syndrome.
PMID: 28864667 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Chhabra A, Lam JM, Rhemus W Tags: J Rheumatol Source Type: research

Demographic and Clinical Characteristics Associated with Central Nervous System Hemorrhage in Patients with Eosinophilic Granulomatosis with Polyangiitis: A Case Report and Review of the Literature.
PMID: 28864668 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Sabio JM, Rivero-Rodriguez M, Vargas-Hitos JA Tags: J Rheumatol Source Type: research

Use of Belimumab throughout 2 Consecutive Pregnancies in a Patient with Systemic Lupus Erythematosus.
PMID: 28864669 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Authors: Kumthekar A, Danve A, Deodhar A Tags: J Rheumatol Source Type: research

Anti-HMGCR Autoantibodies in Juvenile Idiopathic Inflammatory Myopathies Identify a Rare but Clinically Important Subset of Patients.
Authors: PMID: 28864670 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - September 1, 2017 Category: Rheumatology Tags: J Rheumatol Source Type: research

Content and Construct Validity, Reliability, and Responsiveness of the Rheumatoid Arthritis Flare Questionnaire: OMERACT 2016 Workshop Report.
CONCLUSION: The RA-FQ has been developed to identify and measure RA flares. Its review through OMERACT Filter 2.0 shows evidence of reliability, content and construct validity, and responsiveness. These properties merit its further validation as an outcome for clinical trials. PMID: 28811351 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 15, 2017 Category: Rheumatology Authors: Bartlett SJ, Barbic SP, Bykerk VP, Choy EH, Alten R, Christensen R, den Broeder A, Fautrel B, Furst DE, Guillemin F, Hewlett S, Leong AL, Lyddiatt A, March L, Montie P, Pohl C, Scholte Voshaar M, Woodworth TG, Bingham CO Tags: J Rheumatol Source Type: research

Patient Acceptable Symptom State in Knee Osteoarthritis Patients Succeeds Across Different Patient-reported Outcome Measures Assessing Physical Function, But Fails Across Other Dimensions and Rheumatic Diseases.
CONCLUSION: PASS cutoff values for physical function are robust across different PROM in patients with knee OA. Our results indicate that PASS values are not consistent across dimensions and rheumatic diseases, and that the use of a generic PASS value for patients with OA or even patients with other rheumatic diseases might not be justifiable. PMID: 28811352 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 15, 2017 Category: Rheumatology Authors: Mahler EAM, Boers N, Bijlsma JWJ, van den Hoogen FHJ, den Broeder AA, van den Ende CHM Tags: J Rheumatol Source Type: research

The OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging (MRI) Scoring System: Updated Recommendations by the OMERACT MRI in Arthritis Working Group.
CONCLUSION: Updated 2016 RAMRIS recommendations and a research agenda were developed. PMID: 28811353 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 15, 2017 Category: Rheumatology Authors: Østergaard M, Peterfy CG, Bird P, Gandjbakhch F, Glinatsi D, Eshed I, Haavardsholm EA, Lillegraven S, Bøyesen P, Ejbjerg B, Foltz V, Emery P, Genant HK, Conaghan PG Tags: J Rheumatol Source Type: research

Safety and Efficacy of Baricitinib Through 128 Weeks in an Open-label, Longterm Extension Study in Patients with Rheumatoid Arthritis.
CONCLUSION: In a phase IIb study in RA, the safety and tolerability profile of baricitinib, up to 128 weeks, remained consistent with earlier observations, without unexpected late signals. Clinical improvements seen in the 24-week blinded period were maintained during the OLE. PMID: 28811354 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 15, 2017 Category: Rheumatology Authors: Keystone EC, Genovese MC, Schlichting DE, de la Torre I, Beattie SD, Rooney TP, Taylor PC Tags: J Rheumatol Source Type: research

Evidence for Updating the Core Domain Set of Outcome Measures for Juvenile Idiopathic Arthritis: Report from a Special Interest Group at OMERACT 2016.
CONCLUSION: The results of qualitative studies and literature review support the need to expand the JIA Core Set, considering, among other things, additional patient/parent-centered outcomes, clinical data, and imaging data. PMID: 28811355 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 15, 2017 Category: Rheumatology Authors: Morgan EM, Riebschleger MP, Horonjeff J, Consolaro A, Munro JE, Thornhill S, Beukelman T, Brunner HI, Creek EL, Harris JG, Horton DB, Lovell DJ, Mannion ML, Olson JC, Rahimi H, Gallo MC, Calandra S, Ravelli A, Ringold S, Shenoi S, Stinson J, Toupin-April Tags: J Rheumatol Source Type: research