Patient Expectations and Perceptions of Goal-setting Strategies for Disease Management in Rheumatoid Arthritis.
CONCLUSION: Many patients with RA feel unable to communicate their disease burden and treatment goals, which are critically important to them, to their healthcare provider (HCP). Insights gained from these 2 surveys should help to guide patients and HCP to better focus upon mutually defined goals for continued improvement of management and achievement of optimal care in RA. PMID: 26233504 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Strand V, Wright GC, Bergman MJ, Tambiah J, Taylor PC Tags: J Rheumatol Source Type: research

Utility of Select Plasma MicroRNA for Disease and Cardiovascular Risk Assessment in Patients with Rheumatoid Arthritis.
CONCLUSION: The combination of miR-24-3p, miR-26a-5p, and miR-125a-5p had the strongest diagnostic accuracy for RA. Candidate miRNA had little or no association with RA disease activity or subclinical atherosclerosis. PMID: 26233505 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Ormseth MJ, Solus JF, Vickers KC, Oeser AM, Raggi P, Stein CM Tags: J Rheumatol Source Type: research

Comparison Photo Optical Imaging with Musculoskeletal Ultrasound and Clinical Examination in the Assessment of Inflammatory Activity in Proximal Interphalangeal Joints in Patients with Rheumatoid Arthritis and Osteoarthritis.
Abstract OBJECTIVE: Lightscan is a novel, rapid, low-cost, easily operated and noninvasive imaging technology used to assess inflammatory activity in proximal interphalangeal (PIP) joints. The results are calculated automatically. To our knowledge, this is the first comparative study of photo optical imaging (POI), with clinical examination (CE), disease activity score at 28 joints (DAS28)-erythrocyte sedimentation rate (ESR), and musculoskeletal ultrasonography (US) in healthy subjects and patients with rheumatoid arthritis (RA) or osteoarthritis (OA). METHODS: There were 688 PIP joints of both hands examine...
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Amitai I, Werner S, Schicke B, Burmester GR, Minet O, Zabaryło U, Backhaus M, Ohrndorf S Tags: J Rheumatol Source Type: research

Impaired Antiatherogenic Functions of High-density Lipoprotein in Patients with Ankylosing Spondylitis.
CONCLUSION: HDL from patients with AS displays impaired antiatherogenic properties. Attenuation of HDL properties may constitute a link between AS and CVD. PMID: 26233507 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Gkolfinopoulou C, Stratikos E, Theofilatos D, Kardassis D, Voulgari PV, Drosos AA, Chroni A Tags: J Rheumatol Source Type: research

Harmonizing Pain Outcome Measures: Results of the Pre-OMERACT Meeting on Partnerships for Consensus on Patient-important Pain Outcome Domains Between the Cochrane Musculoskeletal Group and OMERACT.
CONCLUSION: Further work is needed on inclusion of the patient perspective in the development of pain domains as well as Cochrane Collaboration summary of findings tables. PMID: 26233508 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Phillips K, Taylor A, Mease PJ, Simon LS, Conaghan PG, Choy EH, Singh JA, Strand V, Gossec L, Kaiser U, de Wit M, Ostelo R, Maxwell L, Tugwell PS Tags: J Rheumatol Source Type: research

Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy.
CONCLUSION: Although adequate exposure and effective peripheral target engagement were evident, JNJ-40346527 efficacy was not observed in patients with DMARD-refractory active RA. ClinicalTrials.gov identifier: NCT01597739. EudraCT Number: 2011-004529-28. PMID: 26233509 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Genovese MC, Hsia E, Belkowski SM, Chien C, Masterson T, Thurmond RL, Manthey CL, Yan XD, Ge T, Franks C, Greenspan A Tags: J Rheumatol Source Type: research

Health Literacy Rates in a Population of Patients with Rheumatoid Arthritis in Southwestern Ontario.
CONCLUSION: Low health literacy is an important issue in the southwestern Ontario RA population. About 1 in 7 patients with RA may not have the necessary skills to become involved in making decisions regarding their personal health. Rheumatologists should be aware of the low health literacy levels of patients with RA and should consider identifying patients at risk of low health literacy. PMID: 26233510 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Gong Z, Haig SL, Pope JE, Rohekar S, Rohekar G, LeRiche NG, Thompson AE Tags: J Rheumatol Source Type: research

Discordance of Global Assessments by Patient and Physician Is Higher in Female than in Male Patients Regardless of the Physician's Sex: Data on Patients with Rheumatoid Arthritis, Axial Spondyloarthritis, and Psoriatic Arthritis from the DANBIO Registry.
ML Abstract OBJECTIVE: To assess the frequency of discordance in patient's (PtGA) and physician's (PGA) global assessment, and to investigate whether higher discordance in female patients compared with male patients is associated with the physician's sex in patients with rheumatoid arthritis (RA), axial spondyloarthritis (axSpA), and psoriatic arthritis (PsA). METHODS: PtGA, PGA, and other patient-related variables were retrieved from the Danish DANBIO registry, used nationwide to monitor patients with RA, axSpA, and PsA. A questionnaire was sent to all physicians registering in DANBIO (n = 265) regarding in...
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Lindström Egholm C, Krogh NS, Pincus T, Dreyer L, Ellingsen T, Glintborg B, Kowalski MR, Lorenzen T, Madsen OR, Nordin H, Rasmussen C, Hetland ML Tags: J Rheumatol Source Type: research

Pronounced Risk of Fractures among Elderly Men Affected by Granulomatosis with Polyangiitis.
Abstract OBJECTIVE: It is unknown whether patients affected by granulomatosis with polyangiitis (GPA) are at increased risk of fractures, and whether the fracture risk in GPA varies with age and sex. The aim of the present study was to compare the fracture risk among patients with GPA with that among age- and sex-matched population controls. METHODS: We established a monocentric cohort of patients treated for GPA at a Danish tertiary care center from 1995 to 2010 (n = 159) and a register-derived GPA cohort identified from the Danish National Hospital Register (n = 402). Each patient was matched with 7 populat...
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Faurschou M, Baslund B, Obel N Tags: J Rheumatol Source Type: research

An Observational Study of Gout Prevalence and Quality of Care in a National Australian General Practice Population.
Abstract OBJECTIVE: The central strategy for effective gout management is longterm urate-lowering therapy to maintain the serum urate at a level below 0.36 mmol/l. We sought to determine the prevalence of gout and the quality of care in a national Australian general practice population. METHODS: Data were from general practice point-of-care electronic records over a 5-year period (n = 1,479,449). Information was collected on patients with gout according to a validated definition. All patients who visited the same general practices over the study period formed the denominator group. We determined the estimated...
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Robinson PC, Taylor WJ, Dalbeth N Tags: J Rheumatol Source Type: research

Pregnancy: Data, Outcomes, and Treatment Paradigms in Rheumatology.
PMID: 26233947 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Kavanaugh A, Cush JJ Tags: J Rheumatol Source Type: research

The Contributions of Whole-body Magnetic Resonance Imaging for the Diagnosis and Management of Chronic Recurrent Multifocal Osteomyelitis.
PMID: 26233948 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Fritz J Tags: J Rheumatol Source Type: research

Silent Joint in Dispute. Is Intraarticular Treatment of Temporomandibular Joint Questionable?
PMID: 26233949 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Herlin T, Pedersen TK Tags: J Rheumatol Source Type: research

A Critical Examination of the Polysymptomatic Distress Scale Construct as a Symptom Severity Questionnaire.
PMID: 26233950 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Friend R, Bennett RM Tags: J Rheumatol Source Type: research

Polyarticular Severe Tophaceous Gout Secondary to Limited Medication Access.
PMID: 26233951 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Kumthekar A, Johnson B Tags: J Rheumatol Source Type: research

Finger Flexion Deformity and Carpal Tunnel Syndrome Caused by Gouty Tophus.
PMID: 26233952 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Kumar V, Rodner C, Lakshminarayanan S Tags: J Rheumatol Source Type: research

A Case Series of Adenosine Deaminase 2-deficient Patients Emphasizing Treatment and Genotype-phenotype Correlations.
n S PMID: 26233953 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Batu ED, Karadag O, Taskiran EZ, Kalyoncu U, Aksentijevich I, Alikasifoglu M, Özen S Tags: J Rheumatol Source Type: research

TNFRSF1A Gene Causing Tumor Necrosis Factor Receptor-associated Periodic Syndrome in 2 Siblings Displaying Variable Disease Severity and Discordant Heterozygosity for an MEFV E148Q Variant.
PMID: 26233954 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Abdwani R, Abdalla E, Al Abrawi S, Al-Thihli K Tags: J Rheumatol Source Type: research

Orbital Myositis and Primary Sjögren Syndrome.
Orbital Myositis and Primary Sjögren Syndrome. J Rheumatol. 2015 Aug;42(8):1536-7 Authors: Danlos FX, Daoued F, Seror R, Mariette X PMID: 26233955 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2015 Category: Rheumatology Authors: Danlos FX, Daoued F, Seror R, Mariette X Tags: J Rheumatol Source Type: research

Development of Cardiovascular Quality Indicators for Rheumatoid Arthritis: Results from an International Expert Panel Using a Novel Online Process.
CONCLUSION: Eleven QI for CVD care in patients with RA have been developed and are rated as highly relevant, valid, and feasible by an international multidisciplinary panel. PMID: 26178275 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Barber CE, Marshall DA, Alvarez N, Mancini GB, Lacaille D, Keeling S, Aviña-Zubieta JA, Khodyakov D, Barnabe C, Faris P, Smith A, Noormohamed R, Hazlewood G, Martin LO, Esdaile JM Tags: J Rheumatol Source Type: research

Barriers to Medication Decision Making in Women with Lupus Nephritis: A Formative Study using Nominal Group Technique.
CONCLUSION: Women with lupus nephritis identified specific barriers to decisions related to medications. Information relevant to known/anticipated medication side effects and medication cost will form the basis of a patient guide for women with systemic lupus erythematosus, currently under development. PMID: 26178276 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Singh JA, Qu H, Yazdany J, Chatham W, Dall'era M, Shewchuk RM Tags: J Rheumatol Source Type: research

Assessing the Reliability of a Semiautomated Segmentation Algorithm for Quantifying Erosions in the Metacarpophalangeal Joints of Patients with Rheumatoid Arthritis.
CONCLUSION: EERA is highly reproducible for quantifying erosions in patients with early RA. PMID: 26178277 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Tomizza MA, Jessome MA, Barbosa J, Beattie KA, Bensen WG, Bobba RS, Cividino AA, Emond PD, Gordon C, Hart L, Ioannidis G, Koh MX, Larché M, Tavares R, Tytus S, Adachi JD Tags: J Rheumatol Source Type: research

Miscarriage and Stillbirth in Women with Rheumatoid Arthritis.
CONCLUSION: The risk of miscarriage was slightly higher among women with RA than in references. PMID: 26178278 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Wallenius M, Salvesen KÅ, Daltveit AK, Skomsvoll JF Tags: J Rheumatol Source Type: research

Comparing Tapering Strategy to Standard Dosing Regimen of Tumor Necrosis Factor Inhibitors in Patients with Spondyloarthritis in Low Disease Activity.
alsa A, Pascual-Salcedo D Abstract OBJECTIVE: To compare clinical outcomes, incidence of flares, and administered drug reduction between patients with spondyloarthritis (SpA) under TNF inhibitor (TNFi) tapering strategy with patients receiving a standard regimen. METHODS: In this retrospective study, 74 patients with SpA from Spain on tapering strategy (tapering group; TG) were compared with 43 patients from the Netherlands receiving a standard regimen (control group; CG). The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) was measured at visit 0 (prior to starting the TNFi), visit 1 (prior to st...
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Plasencia C, Kneepkens EL, Wolbink G, Krieckaert CL, Turk S, Navarro-Compán V, L'Ami M, Nurmohamed MT, van der Horst-Bruinsma I, Jurado T, Diego C, Bonilla G, Villalba A, Peiteado D, Nuño L, van der Kleij D, Rispens T, Martín-Mola E, Balsa A, Pascual-S Tags: J Rheumatol Source Type: research

Nuclear Factor-κB-inducing Kinase Is Expressed in Synovial Endothelial Cells in Patients with Early Arthritis and Correlates with Markers of Inflammation: A Prospective Cohort Study.
Nuclear Factor-κB-inducing Kinase Is Expressed in Synovial Endothelial Cells in Patients with Early Arthritis and Correlates with Markers of Inflammation: A Prospective Cohort Study. J Rheumatol. 2015 Jul 15; Authors: Maijer KI, Noort AR, de Hair MJ, van der Leij C, van Zoest KP, Choi IY, Gerlag DM, Maas M, Tak PP, Tas SW Abstract OBJECTIVE: The nuclear factor-κB (NF-κB) family of transcription factors is strongly involved in synovial inflammation. We have previously shown that NF-κB-inducing kinase (NIK) is a key regulator of inflammation-induced angiogenesis in rheumatoid art...
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Maijer KI, Noort AR, de Hair MJ, van der Leij C, van Zoest KP, Choi IY, Gerlag DM, Maas M, Tak PP, Tas SW Tags: J Rheumatol Source Type: research

Evidence-based Recommendations for the Management of Comorbidities in Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis: Expert Opinion of the Canadian Dermatology-Rheumatology Comorbidity Initiative.
CONCLUSION: These practical evidence-based recommendations can guide management of comorbidities in patients with RA, PsA, and PsO and optimize outcomes. PMID: 26178281 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Siu S, Kraft J, Lynde C, Pope J, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B Tags: J Rheumatol Source Type: research

Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index.
CONCLUSION: This study supports the use of the CCI as a single-joint assessment after single-joint intervention. CLINICAL TRIAL REGISTRATION: NTR-1210. PMID: 26178282 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Aalbers CJ, Gerlag DM, Vervoordeldonk MJ, Tak PP, Landewé RB Tags: J Rheumatol Source Type: research

14-3-3η Autoantibodies: Diagnostic Use in Early Rheumatoid Arthritis.
14-3-3η Autoantibodies: Diagnostic Use in Early Rheumatoid Arthritis. J Rheumatol. 2015 Jul 15; Authors: Maksymowych WP, Boire G, van Schaardenburg D, Wichuk S, Turk S, Boers M, Siminovitch KA, Bykerk V, Keystone E, Tak PP, van Kuijk AW, Landewé R, van der Heijde D, Murphy M, Marotta A Abstract OBJECTIVE: To describe the expression and diagnostic use of 14-3-3η autoantibodies in early rheumatoid arthritis (RA). METHODS: 14-3-3η autoantibody levels were measured using an electrochemiluminescent multiplexed assay in 500 subjects (114 disease-modifying antirheumatic drug-naive pat...
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Maksymowych WP, Boire G, van Schaardenburg D, Wichuk S, Turk S, Boers M, Siminovitch KA, Bykerk V, Keystone E, Tak PP, van Kuijk AW, Landewé R, van der Heijde D, Murphy M, Marotta A Tags: J Rheumatol Source Type: research

Differential Antigen-presenting B Cell Phenotypes from Synovial Microenvironment of Patients with Rheumatoid and Psoriatic Arthritis.
CONCLUSION: Synovial B cells from patients with RA and patients with PsA express different antigen-presenting cell phenotypes, suggesting that this cell type plays a dissimilar role in the pathogenesis of each disease. PMID: 26178284 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Armas-González E, Díaz-Martín A, Domínguez-Luis MJ, Arce-Franco MT, Herrera-García A, Hernández-Hernández MV, Bustabad S, Usategui A, Pablos JL, Cañete JD, Díaz-González F Tags: J Rheumatol Source Type: research

Genetic Variants of the NLRP3 Inflammasome Are Associated with Stroke in Patients with Rheumatoid Arthritis.
Dahlqvist S Abstract OBJECTIVE: Inflammasomes are intracellular protein complexes important for the production of proinflammatory cytokines. Studies have suggested that the NLRP3 inflammasome influences both the severity of rheumatoid arthritis (RA) and development of atherosclerosis. Therefore, we investigated whether functional genetic variants related to the NLRP3 inflammasome influence the risk of cardiovascular (CV) disease (CVD) in patients with RA. METHODS: The incidence of CVD was assessed in 522 patients with established RA by a retrospective survey of medical records in combination with a 6-year pro...
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Kastbom A, Ärlestig L, Rantapää-Dahlqvist S Tags: J Rheumatol Source Type: research

Breastfeeding and Risk of Rheumatoid Arthritis: A Systematic Review and Metaanalysis.
Abstract OBJECTIVE: Previous studies have examined the association between breastfeeding and rheumatoid arthritis (RA), but their results were inconsistent. The aim of this study was to perform a metaanalysis to clarify the effect of breastfeeding on RA risk. METHODS: The PubMed, EMBASE, Chinese National Knowledge Infrastructure, and Wanfang databases were searched for relevant studies published up to September 10, 2014. Data were extracted, and multivariable-adjusted OR with 95% CI were pooled in the random-effects model. RESULTS: A total of 6 studies were included in the metaanalysis (RA cases: 1672, s...
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Chen H, Wang J, Zhou W, Yin H, Wang M Tags: J Rheumatol Source Type: research

Cardiac Function in Adult Patients with Juvenile Idiopathic Arthritis.
CONCLUSION: Adult patients with JIA did not differ from controls in LV systolic function, but had mildly thicker interventricular septum and indications for higher LV filling pressure, and most in patients with a higher disease burden. PMID: 26178287 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Aulie HA, Estensen ME, Selvaag AM, Lilleby V, Murbraech K, Flatø B, Aakhus S Tags: J Rheumatol Source Type: research

Incidence of Cyclophosphamide-induced Urotoxicity and Protective Effect of Mesna in Rheumatic Diseases.
ankara V, Erken E, Direskeneli H, Aksu K, Yavuz S Abstract OBJECTIVE: To assess bladder toxicity of cyclophosphamide (CYC) and uroprotective effect of mesna in rheumatic diseases. METHODS: Data of 1018 patients (725 women/293 men) treated with CYC were evaluated in this retrospective study. All of the following information was obtained: the cumulative CYC dose, route of CYC administration, duration of therapy, concomitant mesna usage, and hemorrhagic cystitis. Cox proportional hazard model was used for statistics. RESULTS: We identified 17 patients (1.67%) with hemorrhagic cystitis and 2 patients (0.19%)...
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Yilmaz N, Emmungil H, Gucenmez S, Ozen G, Yildiz F, Balkarli A, Kimyon G, Coskun BN, Dogan I, Pamuk ON, Yasar S, Cetin GY, Yazici A, Ergulu Esmen S, Cagatay Y, Yilmaz S, Cefle A, Sayarlioglu M, Kasifoglu T, Karadag O, Pehlivan Y, Dalkilic E, Kisacik B, Co Tags: J Rheumatol Source Type: research

Prevalence of Inflammatory Back Pain and Axial Spondyloarthritis Among University Employees in Izmir, Turkey.
Abstract OBJECTIVE: To estimate the prevalence of inflammatory back pain (IBP) and axial spondyloarthritis (axSpA) using the Assessment of SpondyloArthritis International Society (ASAS) classification criteria among employees in a university. METHODS: In the first stage of the study, a face-to-face interview was done using a standard questionnaire to investigate IBP in 381 subjects randomly selected from 2894 employees at Dokuz Eylul University in Izmir, Turkey. In the second stage, subjects with back pain for ≥ 3 months and age at onset
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Onen F, Solmaz D, Cetin P, Sari I, Balci A, Birlik M, Akar S, Akkoc N Tags: J Rheumatol Source Type: research

Patients with Rheumatoid Arthritis in the Australian OPAL Cohort Show Significant Improvement in Disease Activity over 5 Years: A Multicenter Observational Study.
Abstract OBJECTIVE: To evaluate disease activity trends in a large cohort of Australian patients with rheumatoid arthritis (RA) from 2009 to 2014. METHODS: This is a multicenter, cross-sectional, noninterventional study of patients with RA treated in Australia. Patients with RA treated at participating OPAL (Optimising Patient outcome in Australian RheumatoLogy) clinics were included in the study. Data, deidentified by patient, clinic, and clinician, were identified using a purpose-written electronic medical record. Patient demographics, disease onset, medications, and disease measures were analyzed. The Dise...
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Littlejohn G, Roberts L, Bird P, de Jager J, Griffiths H, Nicholls D, Young J, Zochling J, Tymms KE Tags: J Rheumatol Source Type: research

Is Chronic Pain a Disease in Its Own Right? Discussions from a Pre-OMERACT 2014 Workshop on Chronic Pain.
Discussions from a Pre-OMERACT 2014 Workshop on Chronic Pain. J Rheumatol. 2015 Jul 1; Authors: Taylor AM, Phillips K, Taylor JO, Singh JA, Conaghan PG, Choy EH, Tugwell PS, Kaiser U, Strand V, Simon LS, Mease PJ Abstract At the pain workshop held prior to the Outcome Measures in Rheumatology (OMERACT) 12 conference, chronic nonmalignant pain (CP) as a "disease" was discussed, in response to growing interest in this concept and in terms of the effect on the OMERACT Filter 2.0 framework. CP is often assessed as a unidimensional outcome measure; however, if CP is a disease, then outcome measur...
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Taylor AM, Phillips K, Taylor JO, Singh JA, Conaghan PG, Choy EH, Tugwell PS, Kaiser U, Strand V, Simon LS, Mease PJ Tags: J Rheumatol Source Type: research

An Internet-based Controlled Trial Aimed to Improve Osteoporosis Prevention among Chronic Glucocorticoid Users.
CONCLUSION: Among adults at high risk of GIOP, prescription rates were not significantly affected by an online educational video presented at the time of glucocorticoid refill. ClinicalTrials.gov Identifier: NCT01378689. PMID: 26136484 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Warriner AH, Outman RC, Allison JJ, Curtis JR, Markward NJ, Redden DT, Safford MM, Stanek EJ, Steinkellner AR, Saag KG Tags: J Rheumatol Source Type: research

Efficacy of Triamcinolone Hexacetonide versus Methylprednisolone Acetate Intraarticular Injections in Knee Osteoarthritis: A Randomized, Double-blinded, 24-week Study.
Abstract OBJECTIVE: Intraarticular (IA) corticosteroid injections are broadly used in knee osteoarthritis (OA); however, the best corticosteroid agent is not well defined. The aim of the present study was to compare the efficacy of triamcinolone hexacetonide (TH) and methylprednisolone acetate (MA) injections in knee OA. METHODS: Patients with symptomatic knee OA and Kellgren-Lawrence grade II or III were randomized to receive 40 mg of IA TH or MA. Evaluations were performed at 4, 12, and 24 weeks. The primary outcome was a change in the patient's assessment of pain by visual analog scale from baseline to Wee...
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Lomonte AB, de Morais MG, de Carvalho LO, Zerbini CA Tags: J Rheumatol Source Type: research

Development of Image Overlay and Knowledge Transfer Module Technologies Aimed at Enhancing Feasibility and External Validation of Magnetic Resonance Imaging-based Scoring Systems.
CONCLUSION: Semitransparent image overlays and standardized knowledge translation modules for reader training show promise to facilitate reader calibration using MRI-based scoring systems. Based on our experience, knowledge translation modules should emphasize close feedback evaluating performance and reader time efficiency. PMID: 26136486 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Jaremko JL, Pitts M, Maksymowych WP, Lambert RG Tags: J Rheumatol Source Type: research

Outcome of Patients with Systemic Sclerosis in the Intensive Care Unit.
CONCLUSION: This study provides reliable prognostic data in patients with SSc who required ICU admission. The devastating outcome of invasive mechanical ventilation in patients with SSc requires a reappraisal of indications for ICU admission and early identification of patients likely to benefit from noninvasive ventilation. PMID: 26136487 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Pène F, Hissem T, Bérezné A, Allanore Y, Geri G, Charpentier J, Avouac J, Guillevin L, Cariou A, Chiche JD, Mira JP, Mouthon L Tags: J Rheumatol Source Type: research

Quality of Sexual Life in Women with Primary Sjögren Syndrome.
Quality of Sexual Life in Women with Primary Sjögren Syndrome. J Rheumatol. 2015 Jul 1; Authors: Priori R, Minniti A, Derme M, Antonazzo B, Brancatisano F, Ghirini S, Valesini G, Framarino-Dei-Malatesta M Abstract OBJECTIVE: To assess the quality of sexual life of women with primary Sjögren syndrome (pSS) and to identify its correlations with disease activity and damage, quality of life, and mood disorders. METHODS: The quality of sexual life of 24 women with pSS was assessed with the Female Sexual Function Index (FSFI). Twenty-four healthy women, matched by age and hormonal status, wer...
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Priori R, Minniti A, Derme M, Antonazzo B, Brancatisano F, Ghirini S, Valesini G, Framarino-Dei-Malatesta M Tags: J Rheumatol Source Type: research

Report from the OMERACT Hand Osteoarthritis Working Group: Set of Core Domains and Preliminary Set of Instruments for Use in Clinical Trials and Observational Studies.
CONCLUSION: Preliminary core sets for clinical trials of symptom and structure modification and observational studies in hand osteoarthritis, including preliminary instruments and contextual factors, were agreed upon during OMERACT 12. PMID: 26136489 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Kloppenburg M, Bøyesen P, Visser AW, Haugen IK, Boers M, Boonen A, Conaghan PG, Hawker GA, Kvien TK, Landewé R, Uhlig T, Smeets W, Greibrokk E, van der Heijde DM Tags: J Rheumatol Source Type: research

Assessment of Patients with Takayasu Arteritis in Routine Practice with Indian Takayasu Clinical Activity Score.
CONCLUSION: ITAS2010 was discriminatory for activity during the followup, but the agreement between PGA and ITAS2010 was moderate. Future work should include the incorporation of advanced vascular imaging and demonstration of ITAS2010 as a scalable measure and not simply a dichotomous measure of activity/flare versus remission. PMID: 26136490 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Alibaz-Oner F, Aydin SZ, Akar S, Aksu K, Kamali S, Yucel E, Karadag O, Ozer H, Kiraz S, Onen F, Inanc M, Keser G, Akkoc N, Direskeneli H Tags: J Rheumatol Source Type: research

Hybrid 18F-labeled Fluoride Positron Emission Tomography/Magnetic Resonance (MR) Imaging of the Sacroiliac Joints and the Spine in Patients with Axial Spondyloarthritis: A Pilot Study Exploring the Link of MR Bone Pathologies and Increased Osteoblastic Activity.
CONCLUSION: In this study of hybrid 18F-F PET/MRI of patients with active AS, we show that BME rather than chronic changes is associated with osteoblastic activity, while the combination of BME and FD showed the highest 18F-F uptake. The use of PET/MRI in prediction of future syndesmophyte formation in AS needs further exploration in prospective studies. PMID: 26136491 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Buchbender C, Ostendorf B, Ruhlmann V, Heusch P, Miese F, Beiderwellen K, Schneider M, Braun J, Antoch G, Baraliakos X Tags: J Rheumatol Source Type: research

Identifying Trajectories of Pain Severity in Early Symptomatic Knee Osteoarthritis: A 5-year Followup of the Cohort Hip and Cohort Knee (CHECK) Study.
CONCLUSION: Three trajectories of pain were identified. Participants with a BMI> 25, secondary school as highest education level, having at least 3 comorbidities, additional hip pain, and/or whose coping style is worrying are more likely to develop a moderate or mild pain trajectory compared with those without these characteristics. In the management of knee pain in people with early symptomatic OA, attention should also be given to additional factors such as hip pain, other comorbidities, passive coping strategy, and obesity. PMID: 26136492 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Wesseling J, Bastick AN, Ten Wolde S, Kloppenburg M, Lafeber FP, Bierma-Zeinstra SM, Bijlsma JW Tags: J Rheumatol Source Type: research

Smoking - Does It Affect Rheumatoid Arthritis Activity? Does It Matter?
PMID: 26136547 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Leeb BF, Mai HT Tags: J Rheumatol Source Type: research

Common Design and Analysis Issues in Clinical Trials.
PMID: 26136548 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Thorpe KE Tags: J Rheumatol Source Type: research

Does Viral Hemorrhagic Fever Represent Reactive Hemophagocytic Syndrome?
PMID: 26136549 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Cron RQ, Behrens EM, Shakoory B, Ramanan AV, Chatham WW Tags: J Rheumatol Source Type: research

Sustained Remission: An Unmet Need in Patients with Giant-cell Arteritis.
PMID: 26136550 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Cid MC, Alba MA Tags: J Rheumatol Source Type: research

Severe Tophaceous Gout with Radiograph Examination of Diffused Calcified Soft Tissue Tophi.
PMID: 26136551 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 1, 2015 Category: Rheumatology Authors: Oehler E, Pascart T Tags: J Rheumatol Source Type: research