Assessment of Enthesitis in Psoriatic Arthritis.
PMID: 31371660 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2019 Category: Rheumatology Authors: Helliwell PS Tags: J Rheumatol Source Type: research

Treatment of Lyme Arthritis.
PMID: 31371661 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2019 Category: Rheumatology Authors: Steere AC Tags: J Rheumatol Source Type: research

A Great Masquerader: Chronic Active Epstein-Barr Virus for the Rheumatologist.
PMID: 31371662 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2019 Category: Rheumatology Authors: Chhabra A, Alyazidi R, Human A Tags: J Rheumatol Source Type: research

Introduction.
PMID: 31371663 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - August 1, 2019 Category: Rheumatology Authors: March L, Richards B, Gill M, Brooks PM, Shea BJ, Beaton DE, Maxwell LJ, Tunis SR, Grosskleg S, Tugwell P Tags: J Rheumatol Source Type: research

Febuxostat Desensitization in a Patient with Previous Stevens-Johnson Syndrome and HLA-B*58:01 Genotype.
We describe the first case, to our knowledge, of successful desensitization to febuxostat in a young high-risk patient of Filipino descent with HLA-B*58:01 positive genotype and previous drug-induced Stevens-Johnson Syndrome (SJS), with 2 subsequent episodes of a morbilliform rash with repeat exposures to febuxostat. PMID: 31308200 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Tana T, Vadas P Tags: J Rheumatol Source Type: research

MBDA: A Valuable Tool for Medical Decision Making.
Abstract I read with interest the editorial by Dr. Roy Fleischmann on the limitations of the multibiomarker disease activity test (MBDA) in the management of rheumatoid arthritis (RA)1 He provides a comprehensive review of some of the key studies of MBDA in clinical trials and concludes that the "MBDA has not met the test of being a biomarker that can predict who will or will not respond to a specific therapy, who will or will not be able to taper or stop therapy or who will or will not have radiographic progression." PMID: 31308201 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Calabrese LH Tags: J Rheumatol Source Type: research

Outcome Monitoring and Clinical Decision Support in Polyarticular Juvenile Idiopathic Arthritis.
Abstract OBJECTIVE: Inconsistent assessment and treatment may negatively impact juvenile idiopathic arthritis (JIA) outcomes. We aimed to improve polyarticular JIA [Poly-JIA, rheumatoid factor positive and negative] outcomes by standardizing point-of-care disease activity monitoring and implementing clinical decision support (CDS) to reduce treatment variation. METHODS: We performed a quality improvement initiative in an outpatient pediatric rheumatology practice. The interventions, deployed from April-November 2016, included standardized disease activity measurement, disease activity target review, and phase...
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Buckley L, Ware E, Kreher G, Wiater L, Mehta J, Burnham JM Tags: J Rheumatol Source Type: research

Immune-related Adverse Events Associated with Cancer Immunotherapy: A Review for the Practicing Rheumatologist.
Abstract Immune checkpoint inhibitors have revolutionized cancer therapy by blocking inhibitory pathways of the immune system to fight cancer cells. Their use is often limited by the development of autoimmune toxicities, which can affect multiple organ systems and are referred to as immune-related adverse events (irAE). Amongst these are rheumatologic irAE, including inflammatory arthritis, myositis, vasculitis, and others. Rheumatologic irAE seem to be different from irAE in other organs and from traditional autoimmune diseases in that they can occur early or have delayed onset, and can persist chronically, even ...
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Jamal S, Hudson M, Fifi-Mah A, Ye C Tags: J Rheumatol Source Type: research

Dr. Dehlin, et al reply.
Abstract It was with great interest that we read the letter from Watson and colleagues1 describing their investigation of how a primary care diagnosis of gout compares to a primary care diagnostic rule for gout and the 1977 American Rheumatism Association (ARA) classification criteria of acute arthritis of primary gout. They present positive predictive values (PPV) of 74% for the diagnostic rule and 80% for the ARA criteria. PMID: 31308204 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Dehlin M, Landgren AJ, Bergsten U, Jacobsson LTH Tags: J Rheumatol Source Type: research

Pauling and Frech reply.
We presented data demonstrating differences in Raynaud symptom reporting using the Raynaud Condition Score (RCS) diary depending on season of enrollment2. PMID: 31308205 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Pauling JD, Frech TM Tags: J Rheumatol Source Type: research

Changes in the presentation of incident gout and the risk of subsequent flares: a population-based study over 20 years.
Abstract OBJECTIVE: To examine whether a change in the presentation of incident gout happened over the last 20 years and to determine the risk of subsequent gout flares after an initial gout attack. METHODS: All incident cases of gout were identified among residents of Olmsted County, Minnesota diagnosed in 1989-1992 and 2009-2010 according to the earliest date fulfilling the 1977 American Rheumatism Association preliminary criteria, New York or Rome criteria for gout. Patients in both cohorts were then followed for up to five years. Cumulative incidence and personyear methods were used to compare flare rates...
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Elfishawi MM, Zleik N, Kvrgic Z, Michet CJ, Crowson CS, Matteson EL, Bongartz T Tags: J Rheumatol Source Type: research

Effect of Season on Internet Searches for Information on Raynaud Phenomenon.
Abstract I read with great interest the recent article by Pauling, et al 1, which examined factors influencing Raynaud condition score (RCS) diary outcomes in systemic sclerosis (SSc). Patients with SSc were recruited at sites in both the United Kingdom and the United States and completed the RCS at both baseline and 6 months. PMID: 31308207 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Hughes M Tags: J Rheumatol Source Type: research

Impact of treatment on damage and hospitalization in elderly patients with microscopic polyangiitis and granulomatosis with polyangiitis.
CONCLUSION: Immunosuppressive treatment with cyclophosphamide or rituximab in elderly patients with MPA and GPA was associated with development of less permanent organ damage and was not associated with hospitalization. However, higher doses of corticosteroids during the first three months was associated with treatment-related damage and fatal infections. PMID: 31308208 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Weiner M, Goh SM, Mohammad AJ, Hrušková Z, Tanna A, Sharp P, Kang A, Bruchfeld A, Selga D, Chocová Z, Westman K, Eriksson P, Harper L, Pusey CD, Tesaŕ V, Salama AD, Segelmark M Tags: J Rheumatol Source Type: research

Risk of cancer in 767 patients with giant cell arteritis in western Norway: a retrospective cohort with matched controls.
CONCLUSION: In this study of a large and well-characterized cohort of GCA-patients there was no difference in the risk of malignancy in GCA-patients compared to matched population controls. PMID: 31308209 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Brekke LK, Fevang BS, Diamantopoulos AP, Assmus J, Esperø E, Gjesdal CG Tags: J Rheumatol Source Type: research

Dr. Fleischmann replies.
Abstract I am honored that Dr. Calabrese read my editorial, "Value of the multibiomarker disease activity score to predict remission in RA: what does the evidence show?" with interest1 As always, I have great respect for his contributions to rheumatology, particularly in his area of specific expertise; I have also found that he is generally a critical and logical thinker who has advanced our knowledge greatly over the years. PMID: 31308210 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Fleischmann R Tags: J Rheumatol Source Type: research

Suboptimal immunization coverage among Canadian rheumatology patients in routine clinical care.
Abstract OBJECTIVE: To assess vaccination coverage and predictors of vaccination among a Canadian population of rheumatology patients in routine clinical care. METHODS: In this cross-sectional study, consecutive adult patients presenting to a tertiary rheumatology clinic at the McGill University Health Center between May and September 2015 were asked to fill a survey on vaccination. Patients self-identified as having rheumatoid arthritis (RA), systemic autoimmune rheumatic diseases (SARD), spondyloarthropathies (SpA), or other diseases (OD). Multivariate logistical regression analyses were performed to evalua...
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Qendro T, de la Torre ML, Panopalis P, Hazel E, Ward BJ, Colmegna I, Hudson M Tags: J Rheumatol Source Type: research

Hydroxychloroquine and Antimalarials.
iacute;az S Abstract We read the editorial by Sandhu, et al 1 about antimalarial-induced cardiomyopathy in systemic lupus erythematosus2, and we want to point out some inaccuracies in the brief review of the history of antimalarials that they presented. PMID: 31308212 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Caminal-Montero L, Suárez-Díaz S Tags: J Rheumatol Source Type: research

In Psoriatic Arthritis fatigue is driven by inflammation, disease duration, and chronic pain: An observational DANBIO registry study.
CONCLUSION: Fatigue in PsA patients may be driven by clinical inflammatory factors, disease duration, and chronic pain in the absence of inflammation. PMID: 31308213 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Skougaard M, Jørgensen TS, Rifbjerg-Madsen S, Coates LC, Egeberg A, Amris K, Dreyer L, Højgaard P, Guldberg-Møller J, Merola JF, Frederiksen P, Gudbergsen H, Kristensen LE Tags: J Rheumatol Source Type: research

Primary Care Diagnosis of Gout Compared to a Primary Care Diagnostic Rule for Gout and to Classification Criteria.
Abstract We read with interest the recent study by Dehlin and colleagues1, investigating the validity of a gout diagnosis in primary care. We have also investigated how a primary care diagnosis of gout compares to a primary care diagnostic rule for gout and to classification criteria. Our objective was to determine the proportion of patients with a primary care diagnosis of gout who fulfilled the primary care diagnostic rule by Janssens, et al for acute gouty arthritis2 and the 1977 American Rheumatism Association (ARA) criteria for the classification of acute arthritis of primary gout3. PMID: 31308214 [PubMe...
Source: J Rheumatol - July 15, 2019 Category: Rheumatology Authors: Watson L, Muller S, Roddy E Tags: J Rheumatol Source Type: research

Dissociation Between Clinical Benefit and Persistent Urate Lowering in Patients with Chronic Refractory Gout Treated with Pegloticase.
CONCLUSION: Chronic refractory gout patients not achieving protocol-defined persistent urate lowering still achieve significant clinical benefits with pegloticase treatment, suggesting that transient reduction in serum urate may result in sustained clinical benefit. PMID: 31203212 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Pillinger MH, Fields T, Yeo AE, Lipsky PE Tags: J Rheumatol Source Type: research

Musculoskeletal Ultrasound in Systemic Lupus Erythematosus: Systematic Literature Review by the Lupus Task Force of the OMERACT Ultrasound Working Group.
CONCLUSION: This literature review demonstrates the need of further research and validation work to define the role of US as an outcome measurement instrument for the musculoskeletal manifestations in SLE patients. PMID: 31203213 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Wong PC, Lee G, Sedie AD, Hanova P, Inanc N, Jousse-Joulin S, Ohrndorf S, Stoenoiu MS, Keen HI, Terslev L, D'Agostino MA, Bruyn GA Tags: J Rheumatol Source Type: research

Role of carotid ultrasound in addition to SCORE for the cardiovascular risk stratification of patients with psoriatic arthritis.
CONCLUSION: A considerable number of PsA patients have clinical estimated intermediate or high risk of a fatal CV event. Carotid US study detects subclinical vascular disease and may be useful to depict the real risk. The presence of atheroma is only partially explained by the classical CV risk factors. PMID: 31203214 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Martínez-Vidal MP, Andrés M, Jovaní V, Santos-Ramírez C, Romera C, Fernández-Carballido C Tags: J Rheumatol Source Type: research

Methotrexate in the Treatment of Idiopathic Granulomatous Mastitis.
CONCLUSION: Methotrexate monotherapy is an effective treatment for IGM. PMID: 31203215 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Postolova A, Troxell ML, Wapnir IL, Genovese MC Tags: J Rheumatol Source Type: research

Infection rates before and after a diagnosis of IgA vasculitis in childhood: a population-wide study using non-exposed matched controls.
CONCLUSION: In IgAV childhood patients there is an increased long-term risk for a broader spectrum of infections, which is unrelated to SI prior to diagnosis or treatment. This suggests disease specific factors may have a lasting effect on immune-competence in childhood IgAV. PMID: 31203216 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Nossent J, Raymond W, Keen H, Preen DB, Inderjeeth CA Tags: J Rheumatol Source Type: research

Pain-associated mediators and axon pathfinders in fibromyalgia skin cells.
ccedil;eyler N Abstract OBJECTIVE: To investigate whether the expression of cytokine, nociceptionassociated ion channel, and axon guidance genes in skin cells fibromyalgia syndrome (FMS) patients differs from healthy controls potentially contributing to pain and small fiber degeneration in FMS. METHODS: We prospectively recruited 128 patients and 26 healthy controls. All study participants underwent neurological examination and a skin punch biopsy was obtained from the lateral calf and thigh. Skin samples were processed to histologically determine intraepidermal nerve fiber density (IENFD) and for primary fib...
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Evdokimov D, Kreß L, Dinkel P, Frank J, Sommer C, Üçeyler N Tags: J Rheumatol Source Type: research

Renal parenchymal thickness in scleroderma patients is related to intrarenal haemodynamic parameters and Raynaud's renal phenomenon.
Abstract OBJECTIVE: Renal involvement in systemic sclerosis (SSc) range from urinary abnormalities, reduction of glomerular filtrate rate (GFR), high renal resistive index to scleroderma renal crisis (SCR). Intrarenal resistance indices are considered markers of renal scleroderma-associated vasculopathy. The aim of this study is to evaluate renal morphological parameters, such as renal length, parenchymal thickness, atrophy index, renal sinus in SSc patients and to correlate it with renal function and hemodynamic parameters. METHODS: Ninety-two SSc patients and forty healthy controls (HC) were enrolled in thi...
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Antonietta G, Biagio B, Ludovica GM, Viviana Z, Rosario C, Edoardo R Tags: J Rheumatol Source Type: research

Testing the Model for Predicting Effectiveness of Anakinra in Systemic Juvenile Idiopathic Arthritis.
Abstract We read the article by Saccomanno, et al, "Predictors of effectiveness of anakinra in systemic juvenile idiopathic arthritis," with great interest1 They reported that shorter disease duration, fewer active joints, higher ferritin levels, and greater activity of systemic manifestations were independently correlated with achievement of complete clinical response at 1 year (CCR1) in systemic juvenile idiopathic arthritis (sJIA). PMID: 31203219 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Ozen S, Demir S, Batu ED Tags: J Rheumatol Source Type: research

Blood Pressure Variability and Age-related Blood Pressure Patterns in Systemic Lupus Erythematosus.
CONCLUSION: Age-related blood pressure patterns in SLE differ from the general population. Increased visit-to-visit BPV is affected by many disease-specific and traditional cardiovascular factors. Increased diastolic BPV is highly associated with cardiovascular events in SLE. PMID: 31203220 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Stojan G, Magder LS, Petri M Tags: J Rheumatol Source Type: research

Treating Psoriatic Arthritis to Target: Defining Psoriatic Arthritis Disease Activity Score (PASDAS) That Reflects State Of Minimal Disease Activity (MDA).
CONCLUSION: A PASDAS score
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Perruccio AV, Got M, Li S, Ye Y, Gladman DD, Chandran V Tags: J Rheumatol Source Type: research

Correlates of Successful Rheumatoid Arthritis Flare Management: Clinician-driven Treatment, Home-based Strategies, & Medication Change.
CONCLUSION: Flares occur frequently even in patients with low disease activity. Independent of home-based or clinically guided care, making a medication change and having less severe pain during a flare were associated with better flare outcomes. Of interest, the decision to change medications was frequently made without clinical advice. Future directions might address how best to intervene when patients experience flares and whether patient initiated medication changes have adverse outcomes. PMID: 31203222 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Mahmoud TG, Huang J, Frits M, Iannaccone C, Bykerk V, Bingham CO, Weinblatt M, Shadick NA Tags: J Rheumatol Source Type: research

Association between Comorbidities and Quality of Life in Psoriatic Arthritis: Results from a Multicentric Cross-sectional Study (PSAQUAL study).
Abstract OBJECTIVE: In psoriatic arthritis (PsA), comorbidities add to the burden of disease, which may lead to poorer quality of life. The purpose of this study was to evaluate the relationship between comorbidities and quality of life (QoL). METHODS: Patients from a multicentric, cross-sectional study on comorbidities in PsA were included in the analysis. Data on comorbidities were collected and were subsequently used to compute the modified Rheumatic Disease Comorbidity Index (mRDCI). The Medical Outcomes Study Short Form-36 (SF-36) physical (PCS) and mental component (MCS) summary scales were used to asse...
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: W B, X D, E H, P P, V D, Rm F, J P Tags: J Rheumatol Source Type: research

Encounters with Rheumatologists in a Publicly-Funded Canadian Healthcare System: A Population-Based Study.
CONCLUSION: Over a 15-year period, the annual percentage of the population seen by a rheumatologist remained constant and the volume of new patients decreased, while follow up patient encounters increased. Patient encounters per rheumatologist decreased over time. Our findings provide novel information for rheumatology workforce planning. Factors affecting clinical activity warrant further research. PMID: 31203224 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Widdifield J, Bernatsky S, Pope JE, Ahluwalia V, Barber CEH, Eder L, Kuriya B, Ling V, Paterson JM, Thorne C Tags: J Rheumatol Source Type: research

Rituximab Therapy for Systemic Rheumatoid Vasculitis: Indications, Outcomes and Adverse Events.
CONCLUSION: Systemic RV is difficult to treat effectively. Complete remission of RV was achieved in 62% and partial response in 38% of patients within 12 months of rituximab use. Further evidence is needed to inform treatment for patients with RV. PMID: 31203225 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Coffey CM, Richter MD, Crowson CS, Koster MJ, Warrington KJ, Ytterberg SR, Makol A Tags: J Rheumatol Source Type: research

Does Abatacept Increase Postoperative Adverse Events in Rheumatoid Arthritis Compared with Conventional Synthetic Disease-modifying Drugs?
CONCLUSION: Compared with csDMARDs and/or steroids without ABT, adding ABT to the treatment does not appear to increase the incidence rates of postoperative adverse events in RA patients undergoing orthopedic surgery. Large cohort studies should be performed to add evidence for the perioperative safety profile of ABT. PMID: 31203226 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Ito H, Tsuji S, Nakayama M, Mochida Y, Nishida K, Ishikawa H, Kojima T, Matsumoto T, Kubota A, Mochizuki T, Sakuraba K, Matsushita I, Nakajima A, Hara R, Haraguchi A, Matsubara T, Kanbe K, Nakagawa N, Hamaguchi M, Momohara S, JOSRA Consortium Tags: J Rheumatol Source Type: research

Evolution of Pulmonary Function in a Cohort of Interstitial Lung Disease Patients Positive to Antisynthetase Antibodies (ASAB).
CONCLUSION: Improvement of pulmonary function was observed in 67% of the patients, improvement was observed in all ASAB groups and occurred within the 6 months after initiating medical treatment. PMID: 31203227 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: González-Pérez MI, Mejía-Hurtado JG, Pérez-Román DI, Buendía-Roldán I, Mejía M, Falfán-Valencia R, Toledo HNM, Rojas-Serrano J Tags: J Rheumatol Source Type: research

Secukinumab immunogenicity over 52 weeks in patients with psoriatic arthritis and ankylosing spondylitis.
CONCLUSION: Secukinumab treatment was associated with a low (
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Deodhar A, Gladman DD, McInnes IB, Spindeldreher S, Martin R, Pricop L, Porter B, Safi J, Shete A, Bruin G Tags: J Rheumatol Source Type: research

Prevalence and Risk Factors for Major Infections In Patients with Anca-associated Vasculitis. Influence on The Disease Outcome.
CONCLUSION: Our results confirm that major infections are the main cause of death in patients with AAV. PMID: 31203229 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Garcia-Vives E, Segarra-Medrano A, Martinez-Valle F, Agraz I, Solans-Laque R Tags: J Rheumatol Source Type: research

Dr. Tibaldi, et al reply.
Abstract We are pleased by the interest of Ozen and colleagues1 for our work2 and appreciate their choice to test our predictive model of response to anakinra in their cohort of children with systemic juvenile idiopathic arthritis (sJIA). The authors used the same definition of complete clinical response (CCR) as in our study and quantified the activity of systemic disease through the systemic manifestation score (SMS) that we developed2. PMID: 31203230 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Tibaldi J, Saccomanno B, Caorsi R, Ravelli A Tags: J Rheumatol Source Type: research

Orthopaedic Surgery Trend in Rheumatoid Arthritis - results of the National Registry of Hospitalised Patients (CMBD) over a 17 year period (1999-2015). TREND-AR Study.
CONCLUSION: Although the overall OS rate has not changed, there is a decrease in the rate of arthrodesis at all ages, THA in patients under 80 years of age, as well as TKA and ULA in patients under 60 years of age. PMID: 31203231 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 15, 2019 Category: Rheumatology Authors: Peña M, Quirós-Donate J, Fernández EP, Crespí-Villarías N, Costa ED, García-Vadillo A, Espinosa M, Macía-Villa C, Morell-Hita JL, Martinez-Prada C, Villaverde V, Quiroga IM, Guzón-Illescas O, Barbadillo C, Prada MF, Godoy H, Varela AH, Izquierdo M Tags: J Rheumatol Source Type: research

Dr. Kang, et al reply.
Abstract We thank Dr. Rothschild for his interest1 in our article2 on the incidence of arterial and venous thrombosis in antineutrophil cytoplasmic antibody-associated vasculitis (AAV). He raises the interesting issue of susceptibility to both arterial and venous thrombotic events, which is also characteristic of antiphospholipid syndrome. PMID: 31154407 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Kang A, Antonelou M, Wong NL, Tanna A, Arulkumaran N, Tam FWK, Pusey CD Tags: J Rheumatol Source Type: research

Canadian Rheumatology Association Meeting Fairmont The Queen Elizabeth Montreal, Quebec, Canada February - March 2, 2019.
Abstract The 73rd Annual Meeting of The Canadian Rheumatology Association was held at the Fairmont The Queen Elizabeth, Montreal, Quebec, Canada February 27 - March 2, 2019. The program consisted of presentations covering original research, symposia, awards, and lectures. Highlights of the meeting include the following 2019 Award Winners: Distinguished Rheumatologist, Edward Keystone; Distinguished Investigator, Diane Lacaille; Teacher-Educator, Shirley Tse; Emerging Investigator, Glen Hazlewood; Best Abstract on SLE Research by a Trainee - Ian Watson Award, Alexandra Legge; Best Abstract on Clinical or Epidemiolo...
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Silverman ED Tags: J Rheumatol Source Type: research

A Rose by Any Other Name: Classified Accelerated Erosive Osteoarthritis or Calcium Pyrophosphate Deposition Disease, a Clarion for Aggressive Intervention.
Abstract The analysis of accelerated osteoarthritis (OA) by Davis, et al 1 noted the predominantly interphalangeal joint distribution of associated erosions and suggested a likely inflammatory derivation of the process. That description, however, is also applicable to a disorder long recognized as inflammatory in character: calcium pyrophosphate deposition disease (CPPD)2. PMID: 31154409 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Rothschild BM Tags: J Rheumatol Source Type: research

Malignancies In Giant Cell Arteritis: A Population-Based Cohort Study.
CONCLUSION: In this Swedish population-based cohort of GCA, the overall risk for cancer was not increased compared to the background population. However, there was an increased risk for leukemia and a decreased risk for breast and upper gastrointestinal tract cancer. PMID: 31154410 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Stamatis P, Turesson C, Willim M, Nilsson JÅ, Englund M, Mohammad AJ Tags: J Rheumatol Source Type: research

The Effect of Triage Assessments on Identifying Inflammatory Arthritis and Reducing Rheumatology Wait Times in Ontario.
CONCLUSION: Patients triaged and expedited by ERPs resulted in shorter wait times compared to usual care, however some patients with IA/SARD were missed and waited longer. Our findings suggest that ERPs working in a triage role can improve access to care for those patients correctly identified with IA/SARD. Further research needs to identify an ongoing ERP educational process to ensure the success of the model. PMID: 31154411 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Ahluwalia V, Brooks S, Sweezie R, Bell M, Kendzerska T, Widdifield J, Bombardier C, AHRT Investigators Tags: J Rheumatol Source Type: research

Are Thrombotic Events in Antineutrophil Cytoplasmic Antibody-associated Vasculitis Related to the Effect of Antiphospholipid Antibodies?
Abstract The high incidence of thrombotic phenomenon among individuals with antineutrophil cytoplasmic antibody-associated vasculitis (AAV) was the subject of an intriguing article by Kang, et al 1 The reported susceptibility to both arterial and venous thrombotic events is also uniquely characteristic of the antiphospholipid syndrome2,3. PMID: 31154412 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Rothschild BM Tags: J Rheumatol Source Type: research

Long-term drug survival of tumor necrosis factor inhibitors in patients with rheumatoid arthritis.
CONCLUSION: After>12 months of follow-up, more patients with rheumatoid arthritis receiving etanercept remain on treatment compared with other TNFi. PMID: 31154413 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Emery P, Vlahos B, Szczypa P, Thakur M, Jones HE, Woolcott J, Estrella PVS, Rolland C, Gibofsky A, Citera G, Sockalingam S, Marshall L Tags: J Rheumatol Source Type: research

MRI Results Following Discontinuation of Methotrexate in Patients With Rheumatoid Arthritis Treated With Subcutaneous Tocilizumab: The COMP-ACT MRI Substudy.
CONCLUSION: In a subset of patients who achieved low disease activity with TCZ + MTX, MRI changes were minimal in intra-articular inflammation and damage measures in patients who discontinued MTX vs those who continued TCZ + MTX. PMID: 31154414 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Peterfy C, Kremer J, Rigby W, Singer N, Birchwood C, Gill D, Reiss W, Pei J, Michalska M Tags: J Rheumatol Source Type: research

Vascular pathology and osteoarthritis: A systematic review.
CONCLUSION: There is evidence suggesting an association between vascular pathology and risk of hand and knee osteoarthritis with a potential causal relationship for knee osteoarthritis. Based on the limited evidence, it is hard to conclude an association for hip osteoarthritis. Further stronger evidence is needed to determine whether there is a causal relationship. PMID: 31154415 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Hussain SM, Dawson C, Wang Y, Tonkin AM, Chou L, Wluka AE, Cicuttini FM Tags: J Rheumatol Source Type: research

Association of serum Tocilizumab trough concentrations with clinical disease activity index scores in adult rheumatoid arthritis patients.
CONCLUSION: In the first 24 weeks of treatment with SC TCZ injections, TCZ concentrations are associated with clinical improvement, while body weight and BMI are inversely associated with TCZ concentrations. Personalizing the dose of SC TCZ to body weight may improve outcomes of clinical disease activity in RA patients. PMID: 31154416 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Arad U, Elkayam O Tags: J Rheumatol Source Type: research

Insurance Payer type and Income are associated with outcomes after total shoulder arthroplasty.
CONCLUSION: This information can help to risk-stratify patients post-TSA. Future assessments of modifiable mediators of these complications are needed. PMID: 31154417 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - June 1, 2019 Category: Rheumatology Authors: Singh JA, Cleveland JD Tags: J Rheumatol Source Type: research