Long-term safety and effectiveness of tacrolimus in patients with lupus nephritis in Japan: 10-year analysis of the real-world TRUST study
CONCLUSION: Tacrolimus was effective and generally well-tolerated as maintenance therapy for LN in a large cohort of patients in Japan followed for 10 years; almost half of whom remained on therapy for the entire duration of follow-up (www.CLINICALTRIALS: gov: NCT01410747).PMID:38359944 | DOI:10.3899/jrheum.2023-0210 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Tsutomu Takeuchi Naoko Wakasugi Tetsuji Hashida Satoshi Uno Hirofumi Makino Source Type: research

Psychometric properties of patient global assessment in Psoriatic Arthritis: a systematic literature review
CONCLUSION: PtGA is a valid and responsive tool in PsA. Correlations were higher with PROs and weaker with DA composite indices and PhGA. PhGA was usually scored lower than PtGA. A standardized formulation of PtGA would be useful.PMID:38359935 | DOI:10.3899/jrheum.2023-0722 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Elisabetta Chessa Alberto Floris Mattia Congia Maria Maddalena Angioni Matteo Piga Laure Gossec Alberto Cauli Source Type: research

Seasonal Effects on Relapse of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Retrospective Multicenter Cohort Study in Japan (J-CANVAS)
J Rheumatol. 2024 Feb 15:jrheum.2023-1079. doi: 10.3899/jrheum.2023-1079. Online ahead of print.ABSTRACTAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a type of systemic vasculitis characterized by autoantibody development against the neutrophil proteins leukocyte proteinase 3 (PR3)-ANCA and myeloperoxidase (MPO)-ANCA. We previously reported that newly developed AAV in Japan was influenced by seasonal variations and that AAV was less frequently observed in autumn.1.PMID:38359936 | DOI:10.3899/jrheum.2023-1079 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Hiroki Kobayashi Yusuke Yoshida Takashi Kida Nobuyuki Yajima Toshiko Ito-Ihara Takashi Kawaguchi Yutaka Kawahito Shintaro Hirata Japan Collaborative Registry of ANCA –Associated Vasculitis Study Group Source Type: research

Residual Disease Activity In Canadian Patients With Psoriatic Arthritis (PsA) Treated With Advanced Therapies: Results From A Multi-Registry Analysis (UNISON-PsA)
CONCLUSION: There is substantial burden and unmet need for improved therapies for Canadians living with PsA. There is a wide regional variation in outcomes that requires further assessment.PMID:38359937 | DOI:10.3899/jrheum.2023-0716 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Dafna D Gladman Vinod Chandran Cheryl F Rosen Sherry Rohekar Tristan Boyd Lihi Eder Proton Rahman Jan Dutz Jonathan Chan Richard P Haydey Snezana Barac Marie-Claude Lalibert é Tanya Girard Pierre-Andr é Fournier Mitchell Sutton Daniel Pereira Tina Chim Source Type: research

Erosions on T1-weighted MRI vs Radiography of Sacroiliac Joints in Recent-onset Axial SpA: 2-year Data (EMBARK Trial and DESIR Cohort)
CONCLUSION: In recent-onset axSpA, SIJ erosions and erosion change were observed more frequently on MRI than radiography. The significance of interval improvement of MRI erosions warrants further research.PMID:38359938 | DOI:10.3899/jrheum.2023-0906 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Walter P Maksymowych Pascal Claudepierre Manouk de Hooge Robert G Lambert Robert Landew é Anna Molto D ésirée van der Heijde Jack F Bukowski Heather Jones Ron Pedersen Annette Szumski Bonnie Vlahos Maxime Dougados Source Type: research

Understanding the employment landscape in people with systemic sclerosis
CONCLUSION: Health factors alone do not differentiate those who are employed and those who gave up employment. This study lays the groundwork for where SSc-specific efforts in workplace policies/practices should be directed, especially workplace support.PMID:38359939 | DOI:10.3899/jrheum.2023-0975 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Hila Jazayeri Monique Gignac Zareen Ahmad Sindhu R Johnson Source Type: research

Right Care, Right Time, Right Level: With Evidence
J Rheumatol. 2024 Feb 15:jrheum.2023-1037. doi: 10.3899/jrheum.2023-1037. Online ahead of print.ABSTRACTAs the Chief Medical Officer for Highmark Inc. and having been on the health insurance side of medicine since 2008 while actively practicing rural family medicine in Kentucky, I have seen the effect chronic diseases can have on healthcare delivery. From a patient perspective, pain and reduced ability to ambulate cause a reduced quality of life (QOL), which is never acceptable.PMID:38359940 | DOI:10.3899/jrheum.2023-1037 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Timothy D Law Source Type: research

Treatment Patterns and Effectiveness of Tofacitinib in Patients Initiating Therapy for Rheumatoid Arthritis: Results from the CorEvitas Rheumatoid Arthritis Registry
CONCLUSION: Tofacitinib effectiveness (CDAI LDA) was observed in a US real-world setting of patients with RA regardless of tofacitinib regimen, line of therapy, time of initiation, and dose. (ClinicalTrials.gov: NCT04721808).PMID:38359941 | DOI:10.3899/jrheum.2023-0752 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Dimitrios A Pappas Jacqueline O'Brien Page C Moore Rhiannon Dodge Rebecca Germino Karim R Masri Clifton O Bingham Laura C Cappelli Source Type: research

Paget Disease as a Rare Mimicker of Giant Cell Arteritis
J Rheumatol. 2024 Feb 15:jrheum.2023-1160. doi: 10.3899/jrheum.2023-1160. Online ahead of print.ABSTRACTPaget disease (PD) is a skeletal disorder that is characterized by excessive osteoclast activity and subsequent increased osteoblast activity that leads to disorganized bone formation. Here, we report a case of a patient whose symptoms initially raised concern for giant cell arteritis (GCA), but further clinical examination ultimately led to an alternative diagnosis.PMID:38359942 | DOI:10.3899/jrheum.2023-1160 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Madalyn Walsh Jennifer Strouse Brittany Bettendorf Source Type: research

Factors Associated With Treatment Pathways in Early Axial Spondyloarthritis: A Multistate Analysis of the 10-Year Follow-Up of the DESIR Cohort
CONCLUSION: To our knowledge, this was the first study using a multistate model to easily represent different treatment states, detailing the transitions across them and their associated factors. Different time profiles for the management of patients with axSpA were identified, including in those abstaining from treatment up to a significant proportion of patients treated with csDMARDs.PMID:38359943 | DOI:10.3899/jrheum.2023-0933 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Elodie Portier Sylvie Chevret Anouk Walter-Petrich Adeline Ruyssen-Witrand Maxime Dougados Anna Molt ó Source Type: research

Long-term safety and effectiveness of tacrolimus in patients with lupus nephritis in Japan: 10-year analysis of the real-world TRUST study
CONCLUSION: Tacrolimus was effective and generally well-tolerated as maintenance therapy for LN in a large cohort of patients in Japan followed for 10 years; almost half of whom remained on therapy for the entire duration of follow-up (www.CLINICALTRIALS: gov: NCT01410747).PMID:38359944 | DOI:10.3899/jrheum.2023-0210 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Tsutomu Takeuchi Naoko Wakasugi Tetsuji Hashida Satoshi Uno Hirofumi Makino Source Type: research

Psychometric properties of patient global assessment in Psoriatic Arthritis: a systematic literature review
CONCLUSION: PtGA is a valid and responsive tool in PsA. Correlations were higher with PROs and weaker with DA composite indices and PhGA. PhGA was usually scored lower than PtGA. A standardized formulation of PtGA would be useful.PMID:38359935 | DOI:10.3899/jrheum.2023-0722 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Elisabetta Chessa Alberto Floris Mattia Congia Maria Maddalena Angioni Matteo Piga Laure Gossec Alberto Cauli Source Type: research

Seasonal Effects on Relapse of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Retrospective Multicenter Cohort Study in Japan (J-CANVAS)
J Rheumatol. 2024 Feb 15:jrheum.2023-1079. doi: 10.3899/jrheum.2023-1079. Online ahead of print.ABSTRACTAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a type of systemic vasculitis characterized by autoantibody development against the neutrophil proteins leukocyte proteinase 3 (PR3)-ANCA and myeloperoxidase (MPO)-ANCA. We previously reported that newly developed AAV in Japan was influenced by seasonal variations and that AAV was less frequently observed in autumn.1.PMID:38359936 | DOI:10.3899/jrheum.2023-1079 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Hiroki Kobayashi Yusuke Yoshida Takashi Kida Nobuyuki Yajima Toshiko Ito-Ihara Takashi Kawaguchi Yutaka Kawahito Shintaro Hirata Japan Collaborative Registry of ANCA –Associated Vasculitis Study Group Source Type: research

Residual Disease Activity In Canadian Patients With Psoriatic Arthritis (PsA) Treated With Advanced Therapies: Results From A Multi-Registry Analysis (UNISON-PsA)
CONCLUSION: There is substantial burden and unmet need for improved therapies for Canadians living with PsA. There is a wide regional variation in outcomes that requires further assessment.PMID:38359937 | DOI:10.3899/jrheum.2023-0716 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Dafna D Gladman Vinod Chandran Cheryl F Rosen Sherry Rohekar Tristan Boyd Lihi Eder Proton Rahman Jan Dutz Jonathan Chan Richard P Haydey Snezana Barac Marie-Claude Lalibert é Tanya Girard Pierre-Andr é Fournier Mitchell Sutton Daniel Pereira Tina Chim Source Type: research

Erosions on T1-weighted MRI vs Radiography of Sacroiliac Joints in Recent-onset Axial SpA: 2-year Data (EMBARK Trial and DESIR Cohort)
CONCLUSION: In recent-onset axSpA, SIJ erosions and erosion change were observed more frequently on MRI than radiography. The significance of interval improvement of MRI erosions warrants further research.PMID:38359938 | DOI:10.3899/jrheum.2023-0906 (Source: J Rheumatol)
Source: J Rheumatol - February 15, 2024 Category: Rheumatology Authors: Walter P Maksymowych Pascal Claudepierre Manouk de Hooge Robert G Lambert Robert Landew é Anna Molto D ésirée van der Heijde Jack F Bukowski Heather Jones Ron Pedersen Annette Szumski Bonnie Vlahos Maxime Dougados Source Type: research