Pulmonary nodular amyloidosis in sjögren syndrome.
Pulmonary nodular amyloidosis in sjögren syndrome. J Rheumatol. 2015 Jan;42(1):134 Authors: Carbone R, Cosso C, Cimmino MA PMID: 25554807 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - January 1, 2015 Category: Rheumatology Authors: Carbone R, Cosso C, Cimmino MA Tags: J Rheumatol Source Type: research

Hydroxychloroquine-induced Hyperpigmentation of the Skin.
PMID: 25554808 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - January 1, 2015 Category: Rheumatology Authors: Sawalha AH Tags: J Rheumatol Source Type: research

Spontaneous bronchopleural fistula caused by a cavitating rheumatoid mass.
PMID: 25554809 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - January 1, 2015 Category: Rheumatology Authors: Healy CF, Murray JG Tags: J Rheumatol Source Type: research

Spondyloarthritis in african blacks.
PMID: 25554810 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - January 1, 2015 Category: Rheumatology Authors: Maharaj AB, Tak PP Tags: J Rheumatol Source Type: research

Anti-NMDA Receptor Encephalitis in a Patient with Rheumatoid Arthritis.
PMID: 25554811 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - January 1, 2015 Category: Rheumatology Authors: Cuende E, Ruiz L Tags: J Rheumatol Source Type: research

Intravenous immunoglobulin expands regulatory T cells in autoimmune rheumatic disease (letter).
Authors: PMID: 25554812 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - January 1, 2015 Category: Rheumatology Tags: J Rheumatol Source Type: research

The SAPHO Syndrome: A Single-center Study of 41 Adult Patients.
CONCLUSION: Based on our experience, SAPHO can be diagnosed in the elderly. It was not associated with HLA-B27. Soft tissue involvement was common and the bisphosphonates were generally effective on bone involvement. PMID: 25512472 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Aljuhani F, Tournadre A, Tatar Z, Couderc M, Mathieu S, Malochet-Guinamand S, Soubrier M, Dubost JJ Tags: J Rheumatol Source Type: research

Facilitators and Barriers to Adherence in the Initiation Phase of Disease-modifying Antirheumatic Drug (DMARD) Use in Patients with Arthritis Who Recently Started Their First DMARD Treatment.
CONCLUSION: Perceptions about medication and the communication style with, and trust in, the rheumatologist were mentioned the most in relation to starting DMARD. The rheumatologist plays a crucial role in influencing adherence behavior by addressing perceptions about medication, providing information, and establishing trust in the treatment plan. PMID: 25512473 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Pasma A, Van't Spijker A, Luime JJ, Walter MJ, Busschbach JJ, Hazes JM Tags: J Rheumatol Source Type: research

The Interleukin 33/ST2 Axis in Patients with Primary Sjögren Syndrome: Expression in Serum and Salivary Glands, and the Clinical Association.
The Interleukin 33/ST2 Axis in Patients with Primary Sjögren Syndrome: Expression in Serum and Salivary Glands, and the Clinical Association. J Rheumatol. 2014 Dec 15; Authors: Jung SM, Lee J, Baek SY, Lee JH, Lee J, Park KS, Park SH, Kim HY, Kwok SK Abstract OBJECTIVE: To evaluate the expression of interleukin 33 (IL-33) and its receptor in sera and salivary tissues of patients with primary Sjögren syndrome (pSS), and to investigate the association with clinical profiles. METHODS: Serum IL-33 and soluble ST2 (sST2) of 55 patients with pSS and 48 controls were determined by ELISA and as...
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Jung SM, Lee J, Baek SY, Lee JH, Lee J, Park KS, Park SH, Kim HY, Kwok SK Tags: J Rheumatol Source Type: research

Cartilage Thickness of the Knee Joint in Juvenile Idiopathic Arthritis: Comparative Assessment by Ultrasonography and Magnetic Resonance Imaging.
Abstract OBJECTIVE: The functional disability experienced in juvenile idiopathic arthritis (JIA) is primarily caused by joint effusion, synovial membrane hypertrophy, and periarticular soft tissue edema, leading to the degeneration of the osteocartilaginous structures because of the inflammatory process in the synovium. The ability to visualize the inflammatory changes and hence the ensuing osteocartilaginous degeneration is, therefore, of great importance in pediatric rheumatology. Ultrasonography (US) has been validated as a tool for measuring cartilage thickness in healthy children and, previously, we have foun...
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Pradsgaard DO, Fiirgaard B, Spannow AH, Heuck C, Herlin T Tags: J Rheumatol Source Type: research

Switching from Intravenous to Subcutaneous Formulation of Abatacept: A Single-center Italian Experience on Efficacy and Safety.
CONCLUSION: SC ABA showed a risk of relapse in 27% of cases. The reinsertion of the IV administration quickly reinstated disease control. PMID: 25512476 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Reggia R, Franceschini F, Tincani A, Cavazzana I Tags: J Rheumatol Source Type: research

Is Statin Exposure Associated with Occurrence or Better Outcome in Giant Cell Arteritis? Results from a French Population-based Study.
CONCLUSION: Statin exposure was not associated with GCA occurrence in the general population. However, exposure to statins up to 20 months may favor a quicker corticosteroid tapering. Based on those results, statin effect on GCA course should not be definitively ruled out. PMID: 25512477 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Pugnet G, Sailler L, Bourrel R, Montastruc JL, Lapeyre-Mestre M Tags: J Rheumatol Source Type: research

Elevated Serum Levels of Syndecan-1 Are Associated with Renal Involvement in Patients with Systemic Lupus Erythematosus.
Abstract OBJECTIVE: Syndecan-1 (SDC-1) is a major constituent of the endothelial glycocalyx, which plays a role in maintaining vascular homeostasis and functions as a glomerular filtration barrier. SDC-1 is readily shed into the blood under various conditions, but the clinical implication of circulating SDC-1 in patients with systemic lupus erythematosus (SLE) remains unclear. We aimed to investigate the association of serum SDC-1 level with certain clinical manifestations of SLE. METHODS: We measured serum SDC-1 levels by ELISA in 111 patients with SLE, 18 with rheumatoid arthritis (RA), and 20 healthy subje...
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Kim KJ, Kim JY, Baek IW, Kim WU, Cho CS Tags: J Rheumatol Source Type: research

Modifiable Factors Associated with Allopurinol Adherence and Outcomes Among Patients with Gout in An Integrated Healthcare System.
Abstract OBJECTIVE: To identify modifiable patient and provider factors associated with allopurinol adherence and the achievement of a serum urate acid (SUA) goal in gout. METHODS: We identified a retrospective cohort of patients with gout, newly treated with allopurinol. All patient data came from administrative datasets at a large integrated health delivery system. Patients were ≥ 18 years old at time of initial allopurinol dispensing, and had 12 months or more of membership and drug eligibility prior to the index date. Allopurinol adherence was defined as a proportion of days covered ≥ 0.80, evaluate...
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Rashid N, Coburn BW, Wu YL, Cheetham TC, Curtis JR, Saag KG, Mikuls TR Tags: J Rheumatol Source Type: research

Bone Lineage Proteins in the Entheses of the Midfoot in Patients with Spondyloarthritis.
CONCLUSION: Osteoproliferation and abnormal expression of bone lineage proteins, but no inflammatory infiltration, characterize midfoot involvement in patients with SpA. In this sense, tarsitis (or ankylosing tarsitis) resembles the involvement of the spine in patients with AS. Ossification may be in part explained by the differentiation of mesenchymal entheseal cells toward the osteoblastic lineage. PMID: 25512480 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Pacheco-Tena C, Pérez-Tamayo R, Pineda C, González-Chávez SA, Quiñonez-Flores C, Vitelly AU, Inman RD, Aubin JE, Vázquez-Mellado J, Burgos-Vargas R Tags: J Rheumatol Source Type: research

Visual Manifestations in Giant Cell Arteritis: Trend over 5 Decades in a Population-based Cohort.
CONCLUSION: Incidence of visual symptoms has declined over the past 5 decades, and chances of recovery from visual symptoms have improved. However, complete loss of vision is essentially irreversible. Jaw claudication is associated with higher likelihood of development of visual symptoms. PMID: 25512481 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Singh AG, Kermani TA, Crowson CS, Weyand CM, Matteson EL, Warrington KJ Tags: J Rheumatol Source Type: research

Outcome of Takayasu Arteritis with Inactive Disease at Diagnosis: The Extent of Vascular Involvement As a Predictor of Activation.
CONCLUSION: Substantial portions of patients with clinically inactive TA at the time of diagnosis experienced disease activation during followup. Type V disease may be an important predictive factor for disease activation in patients with clinically inactive TA. PMID: 25512482 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Hong S, Bae SH, Ahn SM, Lim DH, Kim YG, Lee CK, Yoo B Tags: J Rheumatol Source Type: research

Remission in Nonradiographic Axial Spondyloarthritis Treated with Anti-tumor Necrosis Factor-α Drugs: An Italian Multicenter Study.
Remission in Nonradiographic Axial Spondyloarthritis Treated with Anti-tumor Necrosis Factor-α Drugs: An Italian Multicenter Study. J Rheumatol. 2014 Dec 15; Authors: Lubrano E, Perrotta FM, Marchesoni A, D'Angelo S, Ramonda R, Addimanda O, Olivieri I, Punzi L, Salvarani C Abstract OBJECTIVE: To investigate the possibility of achieving partial remission (PR) in patients with nonradiographic axial spondyloarthritis (nr-axSpA) versus ankylosing spondylitis (AS) treated with anti-tumor necrosis factor (TNF)-α antagonists, such as adalimumab (ADA), etanercept (ETN), and infliximab (IFX), in a ...
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Lubrano E, Perrotta FM, Marchesoni A, D'Angelo S, Ramonda R, Addimanda O, Olivieri I, Punzi L, Salvarani C Tags: J Rheumatol Source Type: research

Prevalence and Significance of Persistently Positive Antiphospholipid Antibodies in Women with Preeclampsia.
CONCLUSION: The prevalence of aPL among women with preeclampsia is low. aPL can predispose women without risk factors to preeclampsia. PMID: 25512484 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Gonzalez-Echavarri C, Villar I, Ugarte A, Larrieta R, Ruiz-Irastorza G Tags: J Rheumatol Source Type: research

Evaluation of Left Atrial Function by Real-time 3-D Echocardiography in Patients with Systemic Lupus Erythematosus.
Abstract OBJECTIVE: Left atrial function plays a key role in maintaining an optimal cardiac output. Left ventricular diastolic dysfunction has been reported in systemic lupus erythematosus (SLE), but its effect on left atrial function has been largely overlooked. Our aim was to assess left atrial performance using real-time 3-D echocardiography (RT3DE) technology in patients with SLE. METHODS: Our study included 102 patients with SLE without any cardiac symptoms, and 32 healthy controls. According to the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI), al...
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Li K, Wang R, Dai M, Lu J, Zou Y, Yang X Tags: J Rheumatol Source Type: research

Cardiovascular Disease-related Hospital Admissions of Patients with Inflammatory Arthritis.
Abstract OBJECTIVE: Patients with inflammatory arthritis (IA) have an increased risk of cardiovascular diseases (CVD), suggesting a high rate of CVD-related hospitalizations, but data on this topic are limited. Our study addressed hospital admissions for CVD in a primary care-based population of patients with IA and controls. METHODS: All newly diagnosed patients with IA between 2001 and 2010 were selected from electronic medical records of the Netherlands Institute for Health Services Research Primary Care database, representing a national network of general practices. Two control patients matched for age, s...
Source: J Rheumatol - December 15, 2014 Category: Rheumatology Authors: Ursum J, Nielen MM, Twisk JW, Peters MJ, Schellevis FG, Nurmohamed MT, Korevaar JC Tags: J Rheumatol Source Type: research

Intravenous Immunoglobulin May Be an Effective Therapy for Refractory, Active Diffuse Cutaneous Systemic Sclerosis.
Abstract OBJECTIVE: We sought to retrospectively review a single-center experience using intravenous immunoglobulin (IVIG) for the treatment of refractory, active diffuse cutaneous systemic sclerosis (dcSSc). METHODS: The mean modified Rodnan Skin score (mRSS) at baseline was compared to the mRSS at 6, 12, 18, and 24 months post-IVIG initiation by the paired Student t test. Changes in mRSS at 6 and 12 months were also compared to data from historical controls of 3 large, negative, multicenter, randomized clinical trials of other medications [D-penicillamine (D-pen), recombinant human relaxin (relaxin), and or...
Source: J Rheumatol - November 29, 2014 Category: Rheumatology Authors: Poelman CL, Hummers LK, Wigley FM, Anderson C, Boin F, Shah AA Tags: J Rheumatol Source Type: research

Echocardiographic Abnormalities in New-onset Polymyositis/dermatomyositis.
CONCLUSION: TDI is a useful method to detect early cardiac abnormalities complementing the conventional echocardiographic measurements. LV and RV systolic dysfunction found in the acute phase significantly improved during the first 3 months of therapy; however, deterioration of diastolic dysfunction was also observed. PMID: 25433528 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 29, 2014 Category: Rheumatology Authors: Péter A, Balogh A, Szilágyi S, Faludi R, Nagy-Vincze M, Edes I, Dankó K Tags: J Rheumatol Source Type: research

Inhibition of PCSK6 May Play a Protective Role in the Development of Rheumatoid Arthritis.
CONCLUSION: PCSK6 is upregulated in the synovial tissues of patients with RA and has a genetic effect on the risk of RA. Inhibition of PCSK6 may play a protective role in the development of RA. PMID: 25433529 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 29, 2014 Category: Rheumatology Authors: Wang F, Wang L, Jiang H, Chang X, Pan J Tags: J Rheumatol Source Type: research

Patient-reported Joint Count in Juvenile Idiopathic Arthritis: The Reliability of a Manikin Format.
CONCLUSION: Agreement between physician and patient on the number of joints with active arthritis was reasonable. Untrained patients tended to overestimate the presence of arthritis when they marked active joints on a manikin-format joint count. When the patient indicated absence of arthritis, the physician usually confirmed this. As the agreement did not improve at followup, future research should focus on the possibility of achieving this through training. For now, the patient-reported joint count cannot replace the physicians' joint count in clinical practice; it may be used in epidemiological studies with caution. ...
Source: J Rheumatol - November 29, 2014 Category: Rheumatology Authors: Dijkstra ME, Anink J, van Pelt PA, Hazes JM, van Suijlekom-Smit LW Tags: J Rheumatol Source Type: research

Imbalance of Prevalence and Specialty Care for Osteoarthritis for First Nations People in Alberta, Canada.
CONCLUSION: We estimate a 2-fold higher prevalence of OA in the FN population with differential healthcare use. Reasons for higher use of primary care and lower use of specialty services and arthroplasty compared with the general population are not yet understood. PMID: 25433531 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 29, 2014 Category: Rheumatology Authors: Barnabe C, Hemmelgarn B, Jones CA, Peschken CA, Voaklander D, Joseph L, Bernatsky S, Esdaile JM, Marshall DA Tags: J Rheumatol Source Type: research

Radiographic Hip Involvement in Ankylosing Spondylitis: Factors Associated with Severe Hip Diseases.
Abstract OBJECTIVE: To determine the factors associated with severe radiographic hip involvement in patients with ankylosing spondylitis (AS). METHODS: A cross-sectional retrospective study was performed. The patients were classified into 3 groups based on the Bath Ankylosing Spondylitis Radiology Hip Index (BASRI-hip): minimal hip disease, moderate hip disease, and severe hip disease. Demographic, clinical, radiographic, and laboratory data were collected and analyzed. To identify factors associated with severe hip disease, ordinal regression analyses were performed. RESULTS: A total of 256 patients wer...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Zhao J, Zheng W, Zhang C, Li J, Liu D, Xu W Tags: J Rheumatol Source Type: research

Trying to Improve Care: The Morbidity and Mortality Conference in a Division of Rheumatology.
CONCLUSION: The M&MC within the Division of Rheumatology reviews a variety of events. Increased reporting of adverse events can lead to system improvements, and has the potential to improve and promote safer healthcare. PMID: 25362651 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Batthish M, Tse SM, Feldman BM, Baker GR, Laxer RM Tags: J Rheumatol Source Type: research

Obesity Is Associated with Greater Valgus Knee Alignment in Pubertal Children, and Higher Body Mass Index Is Associated with Greater Variability in Knee Alignment in Girls.
Abstract OBJECTIVE: In adults, osteoarthritis (OA) is associated with obesity and knee alignment. Whether knee alignment differences develop during childhood and are associated with obesity is unknown. We assessed the distribution of knee alignment in children and adolescents, and determined how knee alignment differs between obese and nonobese children. METHODS: This cross-sectional study examined knee alignment in 155 healthy weight and 165 obese subjects. Knee alignment [metaphyseal-diaphyseal angle (MDA) and anterior tibiofemoral angle (ATFA)] and fat mass were measured using whole body dual-energy X-ray ...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Bout-Tabaku S, Shults J, Zemel BS, Leonard MB, Berkowitz RI, Stettler N, Burnham JM Tags: J Rheumatol Source Type: research

Ultrasonographic Evaluation of the Anterior Chest Wall in Spondyloarthritis: A Prospective and Controlled Study.
Abstract OBJECTIVE: To determine the prevalence and type of ultrasonographic (US) lesions of the anterior chest wall (ACW) in cases of spondyloarthritis (SpA). METHODS: This monocentric, prospective, and controlled study included patients consulting for SpA (Assessment of Spondyloarthritis International Society criteria) and control subjects. Clinical (pain and swelling) and US assessments (synovitis, joint effusion, erosion, ankylosis, margin narrowing, or Doppler signal) were performed on the sternoclavicular (SCJ) and the manubriosternal (MSJ) joints. The main characteristics of SpA were recorded [disease ...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Verhoeven F, Guillot X, Godfrin-Valnet M, Prati C, Wendling D Tags: J Rheumatol Source Type: research

Treatment with Tumor Necrosis Factor Inhibitors in Axial Spondyloarthritis: Comparison Between Private Rheumatology Practices and Academic Centers in a Large Observational Cohort.
CONCLUSION: With the exception of a lower proportion of patients with nr-axSpA newly treated with anti-TNF agents in private practices in comparison to academic centers, adherence to ASAS treatment recommendations for TNF inhibition was equally high, and similar response rates to TNF blockers were achieved in both clinical settings. PMID: 25362654 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Ciurea A, Weber U, Stekhoven D, Scherer A, Tamborrini G, Bernhard J, Toniolo M, Villiger PM, Zufferey P, Kissling RO, Michel BA, Exer P, on behalf of the Rheumatologists of Swiss Clinical Quality Management Tags: J Rheumatol Source Type: research

Osteoprotegerin Concentrations Relate Independently to Established Cardiovascular Disease in Rheumatoid Arthritis.
ay MA, Dessein PH Abstract OBJECTIVE: We determined whether osteoprotegerin (OPG) concentrations are associated with established cardiovascular disease (CVD) among patients with rheumatoid arthritis (RA). METHODS: OPG concentrations were measured by ELISA in 151 patients with RA (54 with CVD) and 62 age-matched control subjects without CVD. Established CVD was composed of documented ischemic heart disease, cerebrovascular disease, and peripheral artery disease. RESULTS: In patients with RA, age, body mass index (BMI), rheumatoid factor (RF) positivity, anticyclic citrullinated peptide (anti-CCP) antibody...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: López-Mejias R, Ubilla B, Genre F, Corrales A, Hernández JL, Ferraz-Amaro I, Tsang L, Llorca J, Blanco R, González-Juanatey C, Gonzalez-Gay MA, Dessein PH Tags: J Rheumatol Source Type: research

Longitudinal Evaluation of PROMIS-29 and FACIT-Dyspnea Short Forms in Systemic Sclerosis.
CONCLUSION: PROMIS-29 and FACIT-Dyspnea are valid instruments to measure health status and dyspnea in patients with SSc. In physical function assessment, longer PROMIS short forms or computer adaptive testing should be considered to improve responsiveness to the effect of skin disease changes on physical function in patients with SSc. PMID: 25362656 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Hinchcliff ME, Beaumont JL, Carns MA, Podlusky S, Thavarajah K, Varga J, Cella D, Chang RW Tags: J Rheumatol Source Type: research

Ankylosing Spondylitis without Axial Progression: Analysis of Associated Factors.
CONCLUSION: Clinical factors associated with this lack of progression were female sex and low ESR. PMID: 25362657 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Montilla C, Díaz-Alvarez A, Calero-Paniagua I, Font P, Collantes-Estevez E, Almodovar R, Zarco P, Queiro-Silva R, Cañete JD, Juanola X, Mulero J, de Miguel E, Gratacós J, on behalf of the REGISPONSER Study Group Tags: J Rheumatol Source Type: research

Projected Worldwide Disease Burden from Giant Cell Arteritis by 2050.
CONCLUSION: Projecting disease burden for GCA on a global scale allows for optimization of healthcare planning and prioritization of research domains. Additional population-based studies are required to more accurately project worldwide disease burden. Our work highlights the future global disease burden of GCA, and illustrates the associated financial implications. PMID: 25362658 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: De Smit E, Palmer AJ, Hewitt AW Tags: J Rheumatol Source Type: research

Etiopathogenic Role of Surfactant Protein D in the Clinical and Immunological Expression of Primary Sjögren Syndrome.
CONCLUSION: In pSS, high SP-D levels were found in patients with severe glandular involvement, hypergammaglobulinemia, leukopenia, extraglandular manifestations, and positive anti-Ro/La antibodies. The specific association between SP-D levels and pulmonary and renal involvements may have pathophysiological implications. PMID: 25362659 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Soto-Cárdenas MJ, Gandía M, Brito-Zerón P, Arias MT, Armiger N, Bové A, Bosch X, Retamozo S, Akasbi M, Pérez-De-Lis M, Gueitasi H, Kostov B, Pérez-Alvarez R, Siso-Almirall A, Lozano F, Ramos-Casals M Tags: J Rheumatol Source Type: research

Serum Soluble Bone Turnover Biomarkers in Psoriatic Arthritis and Psoriatic Spondyloarthropathy.
The objectives of our systematic review were to determine whether serum soluble bone and cartilage turnover biomarkers are (1) associated with PsA or psoriatic spondyloarthropathy; and (2) associated with disease activity, disease severity, or clinical phenotype. Ten studies met eligibility criteria. Matrix metalloproteinase (MMP)-3, Dickkopf (DKK)-1, macrophage colony-stimulating factor (M-CSF), crosslinked telopeptide of collagen-1, and tumor necrosis factor-related apoptosis-inducing ligand were associated with PsA, with equivocal results for osteoprotegerin (OPG) and bone alkaline phosphatase (ALP). MMP-3, DKK-1, M-CSF...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Jadon DR, Nightingale AL, McHugh NJ, Lindsay MA, Korendowych E, Sengupta R Tags: J Rheumatol Source Type: research

Understanding Limitations in At-work Productivity in Patients with Active Ankylosing Spondylitis: The Role of Work-related Contextual Factors.
CONCLUSION: Both health-related and contextual factors contribute to work limitations in patients with AS and suggest additional opportunities for improvement by addressing the working environment. PMID: 25362661 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Boonen A, Boone C, Albert A, Mielants H Tags: J Rheumatol Source Type: research

Something old, something new: biomarkers in rheumatoid arthritis.
PMID: 25362703 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Pratesi F, Migliorini P Tags: J Rheumatol Source Type: research

Cardiovascular events in early rheumatoid arthritis - role of tumor necrosis factor inhibition.
PMID: 25362704 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Ljung L Tags: J Rheumatol Source Type: research

Law of the vital few: choosing variables of disease activity in rheumatoid arthritis.
PMID: 25362705 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Dumitru B, Buch M, Vital EM Tags: J Rheumatol Source Type: research

Still trying to understand methotrexate.
PMID: 25362706 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Kremer JM Tags: J Rheumatol Source Type: research

Human and Viral microRNA Expression in Sjögren Syndrome.
Human and Viral microRNA Expression in Sjögren Syndrome. J Rheumatol. 2014 Nov;41(11):2102-3 Authors: Cotrim AP, Alevizos I PMID: 25362707 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Cotrim AP, Alevizos I Tags: J Rheumatol Source Type: research

Septic Arthritis and Osteomyelitis of the Hip by Candida albicans.
PMID: 25362708 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Taneja AK, Torriani M, Simeone FJ Tags: J Rheumatol Source Type: research

Erysipelas-like Erythema in a Patient with Familial Mediterranean Fever.
PMID: 25362709 [PubMed - in process] (Source: J Rheumatol)
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Breuer GS, Taurog JD Tags: J Rheumatol Source Type: research

Systematic Review of Treatments for Psoriatic Arthritis: 2014 Update for the GRAPPA.
Abstract Psoriatic arthritis (PsA) is a chronic systemic inflammatory disorder characterized by the association of arthritis and periarticular inflammation in patients with psoriasis. In addition to a heterogeneous and variable clinical course, PsA is complex and multifaceted and may include prominent involvement in the peripheral and axial diarthrodial joints, the skin and nails, and in periarticular structures such as entheses. Simultaneous inflammation in the skin and musculoskeletal structures in a single patient, a relatively common scenario, often leads to marked decrease in function and quality of life. Thu...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Coates LC, Kavanaugh A, Ritchlin CT, GRAPPA Treatment Guideline Committee Tags: J Rheumatol Source Type: research

Drug therapies for peripheral joint disease in psoriatic arthritis: a systematic review.
Abstract In 2009, GRAPPA published their first evidence-based recommendations for the treatment of psoriasis and psoriatic arthritis (PsA). Since then, new information has been published and drugs developed. We summarize evidence for the efficacy of available treatments for peripheral joint involvement in PsA. We performed a systematic review of current literature on the efficacy of different therapies, management, and therapeutic strategies for peripheral arthritis involvement in PsA, in order to provide information for the development of the new GRAPPA treatment recommendations. PMID: 25362711 [PubMed - in ...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Acosta Felquer ML, Coates LC, Soriano ER, Ranza R, Espinoza LR, Helliwell PS, FitzGerald O, McHugh N, Roussou E, Mease PJ Tags: J Rheumatol Source Type: research

Updated guidelines for the management of axial disease in psoriatic arthritis.
Abstract Axial involvement in patients with psoriatic arthritis (PsA) remains common and can be defined in terms of spinal disease alone or in combination with peripheral manifestations. Diagnosis is based upon inflammatory spinal symptoms or the presence of radiological sacroiliitis and other radiographic signs of spondylitis, or by criteria for axial spondyloarthritis (SpA) defined by ASAS (Assessment of SpondyloArthritis International Society). Although recent data are scarce for efficacy of traditional therapies for axial disease (e.g., nonsteroidal antiinflammatory drugs, methotrexate, etc.), limited data are...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Nash P, Lubrano E, Cauli A, Taylor WJ, Olivieri I, Gladman DD Tags: J Rheumatol Source Type: research

Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis.
Abstract Enthesitis is a characteristic feature of psoriatic arthritis (PsA) and is important in disease pathogenesis and classification. Use of clinical outcome measures for enthesitis is heterogeneous, and only 1 measure has been specifically developed and validated in PsA. Ultrasound and magnetic resonance imaging assessments of enthesitis may have advantages over clinical examination but are insufficiently studied. As part of an update of treatment recommendations by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), we performed a systematic literature review and identified r...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Orbai AM, Weitz J, Siegel EL, Siebert S, Savage LJ, Aydin SZ, Luime JJ, Elkayam O, Neerinckx B, Urbancek S, de Vlam K, Ritchlin CT, GRAPPA Enthesitis Working Group Tags: J Rheumatol Source Type: research

Comprehensive treatment of dactylitis in psoriatic arthritis.
Abstract Dactylitis, a hallmark clinical feature of psoriatic arthritis (PsA) and other spondyloarthropathies, may also be a severity marker for PsA and psoriasis. Traditionally, clinicians have used nonsteroidal antiinflammatory drugs and local corticosteroid injections to treat dactylitis, although conventional disease-modifying antirheumatic drugs are also used. We performed a systematic literature review to determine the most efficacious current treatment options for dactylitis in PsA. Effect sizes were greatest for the biologic agents ustekinumab, certolizumab, and infliximab, suggesting that therapy with one...
Source: J Rheumatol - November 1, 2014 Category: Rheumatology Authors: Rose S, Toloza S, Bautista-Molano W, Helliwell PS, GRAPPA Dactylitis Study Group Tags: J Rheumatol Source Type: research