Patient information leaflet in the era of digitalisation: a cross-sectional study on patients ’ attitudes and practices
ConclusionAlthough patients had positive perceptions towards PILs, physicians were the top-consulted source for medicine information. Pharmacists should educate patients about the importance of referring to PILs which can also be accessed electronically in the case of a preference for a digital format, as the quality and reliability of the information obtained from the web cannot be confirmed. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 7, 2023 Category: General Medicine Source Type: research

Association of clinical biomarkers and response to neoadjuvant therapy in breast cancer
ConclusionpCR was more likely in patients with less advanced disease in BC. The presence of HER2  + or TNBC in BC also increases the likelihood of pCR. Neoadjuvant therapy stimulates the systemic inflammatory response; however, a reduced baseline NLR may be associated with increased pCR. Confirmation with larger datasets is required. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 7, 2023 Category: General Medicine Source Type: research

Diagnostic value of pulsed wave doppler in pneumothorax: a prospective study
ConclusionPW  Doppler is a useful tool in the diagnosis of pneumothorax. It has a high sensitivity and specificity for the detection of pneumothorax. It is also superior to both lung sliding and the barcode sign in detecting pneumothorax. The Dogan’s sign can be used safely in the diagnosis of pneumothorax, t ogether with lung sliding and the barcode sign. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 7, 2023 Category: General Medicine Source Type: research

Alcohol availability and accessibility around schools in Ireland: an examination of liquor licences proximity
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 7, 2023 Category: General Medicine Source Type: research

Utility of shear wave elastography for diagnosing carpal tunnel syndrome with psoriatic arthritis
ConclusionsWe found that SWE has a good diagnostic value for CTS with PsA patients; hence, we can conclude that SWE could diagnose CTS in PsA patients. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 6, 2023 Category: General Medicine Source Type: research

Potential of near-infrared spectroscopy (NIRS) as a non-invasive diagnostic tool to contain a global outbreak of malaria
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 4, 2023 Category: General Medicine Source Type: research

Cognitive behavioral stress management is an effective intervention to relieve anxiety and depression, improve the quality of life in patients with cervical cancer
ConclusionCBSM is an effective intervention for decreasing anxiety and depression, and improving quality of life in patients with cervical cancer. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 1, 2023 Category: General Medicine Source Type: research

RV size may predict death in unstable patients with PE
ConclusionsClinical parameters and hematological parameters could predict death of patients admitted with acute PE. RV diameter, measured by the non-ECG gated CTPA, had an additive predictive value for patients who admitted to the ICU. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 28, 2023 Category: General Medicine Source Type: research

Incidence of histologic chorioamnionitis in a rural community hospital
ConclusionsEvaluation of the incidence of HCA and associated clinical parameters in this study showed a marked decrease in the incidence of HCA when compared to other studies. Strategies to reduce the incidence of HCA include reducing the length of labor via active labor management. We hypothesize that these findings are due to the consistent use of active labor management and our rural study population, but further investigation is required to confirm this. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 28, 2023 Category: General Medicine Source Type: research

Serum soluble α-Klotho levels in patients with diabetic nephropathy
ConclusionsSoluble α-Klotho levels in the sera of diabetic patients were shown to be lower and significantly linked to patients with diabetic nephropathy. This implies that klotho levels may be influenced by ACR in addition to playing a significant role in insulin resistance. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 26, 2023 Category: General Medicine Source Type: research

The effect of nonpharmacological interventions applied by nurses to intensive care patients on the duration of delirium: a meta-analysis study
ConclusionNonpharmacological interventions applied by nurses, who have significant responsibilities in the protection and promotion of health, were found to reduce the duration of delirium in intensive care patients. This study shows that nurses, one of the main components of the multidisciplinary team in intensive care, are successful when they apply nonpharmacological interventions well. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 25, 2023 Category: General Medicine Source Type: research

PARP14 correlates with GBM proliferation and poor prognosis by elevating expression of SAMD/SAMD9L
ConclusionsPARP14, SAMD9, and SAMD9L are prognostic biomarkers of GBM predicting poor prognosis. PARP14 promotes GBM cell proliferation by inducing SAMD9 and SAMD9L expression. Our results indicate that PARP14/SAMD9/SAMD9L are prognostic biomarkers and potential drug targets of GBM. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 24, 2023 Category: General Medicine Source Type: research

Nephrectomy for xanthogranulomatous pyelonephritis —a not-so-simple solution
ConclusionsXGP is a difficult and complex condition to treat. All patients in this series presented with infection or associated sequelae thereof. Complex XGP cases therefore often require open nephrectomy and have high rates of postoperative complications. Careful consideration of antibiotic and operative intervention is therefore essential to ensure the best outcome for these patients. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 23, 2023 Category: General Medicine Source Type: research

Palliative radiotherapy and the introduction of a Rapid Access Palliative Clinic in a national radiation oncology network
ConclusionsReferral rates to SPC services and documentation of performance status were low in our 30DM retrospective review cohort. The RAPC facilitated quick treatment turnaround, fewer hospital visits and referral to SPC services. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 22, 2023 Category: General Medicine Source Type: research

The reliability and validity of the balance tests in hearing-impaired athletes
ConclusionIt was revealed that the balance of hearing-impaired athletes was comparable to the balance of healthy athletes in test conditions in which visual information could be used effectively. For this reason, it is important to consider the visual information factor when evaluating the balance of hearing-impaired athletes. Additionally, taking into account time and tiredness, FT for static balance and FSST for dynamic balance may be helpful to evaluate hearing-impaired athletes. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - August 22, 2023 Category: General Medicine Source Type: research