Asylum Doctor Extraordinaire: Dr. Thomas Drapes (1847–1919)
Abstract Dr. Thomas Drapes (1847–1919) was resident medical superintendent of Enniscorthy District Asylum in County Wexford, Ireland from 1883 to 1919, and one of the leading figures in Irish asylum medicine for several decades. Drapes’ career was as complex as it was remarkable. Drapes was elected president of the Medico-Psychological Association for the term 1911–12 but had to decline on health grounds. In 1912, however, he was unanimously elected as co-editor of the Journal of Mental Science, to which he devoted his considerable energies and intellect. Drapes published widely, opposing Emil Kr...
Source: Irish Journal of Medical Science - April 2, 2015 Category: Journals (General) Source Type: research

Brain metastasis from colorectal carcinoma: a single cancer centre experience
Conclusion With increased survival, improved systemic therapy and aggressive approaches to surgical management of “classical” metastases from CRC, it is likely that a changing pattern of metastases will emerge. As survival rates increase, we propose that metastatic sites, which were previously considered rare (e.g. brain), will now become more common and thus, surgeons must recognise pertinent symptomatology. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 23, 2015 Category: Journals (General) Source Type: research

Systematic analysis to identify a key role of CDK1 in mediating gene interaction networks in cervical cancer development
Conclusion CDK1 plays a comprehensive role in mediating genetic networks implicated in the progression of cervical cancer. Novel therapeutics targeting CDK1 or its related pathways might help improve prognosis of advanced stage cervical cancer. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 19, 2015 Category: Journals (General) Source Type: research

Six-core versus twelve-core prostate biopsy: a retrospective study comparing accuracy, oncological outcomes and safety
Abstract Aims To compare sextant and 12 core transrectal ultrasound-guided (TRUS) prostate biopsies for detecting prostate cancer (PCa) and to determine whether 12-core prostate biopsies are associated with a higher incidence of insignificant prostate cancer and complications. Methods A retrospective study was performed on all patients with a positive TRUS biopsy for prostate cancer between January 2011 and December 2013. Group A underwent a sextant core prostate biopsy and group B underwent a 12-core prostate biopsy. Outcome variables were cancer detect...
Source: Irish Journal of Medical Science - March 19, 2015 Category: Journals (General) Source Type: research

Erratum to: Malignant melanoma: factors affecting the surgical interval from excision biopsy to definitive surgical management
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 18, 2015 Category: Journals (General) Source Type: research

Variable phenotypes in Greig cephalopolysyndactyly sydrome (GCPS) and their relevance to plastic surgery
Conclusion An awareness of the diversity in phenotypes is important for diagnosis and early referral for genetic confirmation and counselling. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 17, 2015 Category: Journals (General) Source Type: research

A novel rapid access testicular cancer clinic: prospective evaluation after one year
Conclusion The RATC is a new initiative in Ireland that provides expedient and definitive treatment of patients with newly diagnosed TCa. Early treatment will ultimately improve long-term prognosis in this patient cohort. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 14, 2015 Category: Journals (General) Source Type: research

The professionalisation of Irish medicine in the generations before Charles Lucas
Abstract The educational opportunities and qualifications, corporate structures and regulation that had become accepted features of the Irish medical profession in the era of Charles Lucas were the fruits of a slow process of professionalization initiated by a handful of Irish medics who, from the 1620s, began tackling poor standards of medical practice in an era of medical pluralism. This paper begins by reviewing the standard of practice in early seventeenth-century Ireland. Through the examples of Thomas Arthur, M.D. and John Clavell, a self-styled medic, differences in the approaches adopted by university-trai...
Source: Irish Journal of Medical Science - March 14, 2015 Category: Journals (General) Source Type: research

Implementation of a surgical handover tool in a busy tertiary referral centre: a complete audit cycle
Abstract Background The implementation of the European work-time directive has created increased transitions of care during weekends as doctors adhere to a shift-work structure. This raises concerns over continuity of care and patient safety. To address this, doctors must develop a time efficient yet safe system of handover of patients to the team on-call. Intuitively weekend care provides the ideal setting to develop a handover tool. Aim To develop and implement a process of surgical handover and to improve weekend discharge rate on a surgical servi...
Source: Irish Journal of Medical Science - March 14, 2015 Category: Journals (General) Source Type: research

Significant reduction in alcohol-related admissions to an intensive care unit in Dublin
Conclusion There has been a significant reduction in the ICU workload from alcohol-related admissions in our general ICU in the past 5 years. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 14, 2015 Category: Journals (General) Source Type: research

The Irish contribution to the plastic surgery literature: 21 years of publications
Discussion The number of publications per year continues to increase along with authorship numbers. This mirrors the trend in other specialties. Publications are now no longer required for selection on to a higher surgical training scheme. There is now a fear that the academic output of trainees will decrease as a consequence. To prevent this, each unit must actively support and encourage research activity with their trainees. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 14, 2015 Category: Journals (General) Source Type: research

Prostate cancer: active surveillance may prove organisationally impossible
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 5, 2015 Category: Journals (General) Source Type: research

Predicting difficult airways: 3-3-2 rule or 3-3 rule?
Conclusions The 3-3 rule and the 3-3-2 rule are similar regarding their ability to predict difficult airways. A HTD less than two fingers or one finger is not predictive of DV or DI. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 5, 2015 Category: Journals (General) Source Type: research

Twitter expands the reach and engagement of a national scientific meeting: the Irish Society of Urology
Conclusion Twitter use at the ISU has been shown to facilitate interaction between delegates and allows users to follow as well as participate from afar. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 5, 2015 Category: Journals (General) Source Type: research

General practitioner ENT referral audit
Conclusion This study demonstrates poor compliance rates with the introduced ICGP standardised referral form, which has implications for the accurate grading of referral letters received. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 1, 2015 Category: Journals (General) Source Type: research

Anatomic study of infrapatellar branch of saphenous nerve in male cadavers
Conclusion By enriching the knowledge of these variable anatomical position of the IPBSN, surgeon can try to minimize the risk of nerve damage by avoiding the high risk zones while performing medial knee incision, blind puncture or an arthrotomy thus avoiding the unwanted complications. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 1, 2015 Category: Journals (General) Source Type: research

Primary care teams in Ireland: a qualitative mapping review of Irish grey and published literature
Conclusion There is evidence of significant problems that disrupt team formation and functioning that warrants more comprehensive research. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 1, 2015 Category: Journals (General) Source Type: research

Urine l -carnitine excretion in hypertensive adolescents
Conclusion The results of this study do not explain the increased urine levels of l-carnitine. The most likely reason for excessive urinary loss was disturbed renal tubular reabsorption. It is possible to hypothesize that in hypertensive adolescents subclinical kidney dysfunction occurs. It is proposed that studies examining the concurrent plasma and urine concentration of l-carnitine and correlation with acknowledged proximal tubular markers are needed. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - March 1, 2015 Category: Journals (General) Source Type: research

Predicting mortality following hip fracture: an analysis of comorbidities and complications
Abstract Background Hip fracture is common in the geriatric population. These patients have multiple comorbidities that complicate treatment and recovery such that poor functional outcomes often result. Since functional outcomes are associated with comorbidities and complications it is important to define the contributing factors. Aims To describe comorbidities common to geriatric hip fracture patients and determine predictability of complications and mortality based on comorbidities. Methods Data in this study wer...
Source: Irish Journal of Medical Science - February 26, 2015 Category: Journals (General) Source Type: research

Sponsors 2015 The 23 rd Sylvester O’Halloran Surgical Scientific Symposium greatly acknowledges the support given to the meeting by the following companies:
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 18, 2015 Category: Journals (General) Source Type: research

Effective communication enhances the patients’ endoscopy experience
Abstract Background Undergoing an endoscopy is a stressful experience for patients. Aims To audit the endoscopy pathway to improve patient satisfaction. Methods A prospective survey of endoscopy patients to identify system improvements that were then implemented. Results The survey was performed before (N = 71) and after (N = 60) process improvements identified by the initial survey. Information provision and staff communication skills were identified for ...
Source: Irish Journal of Medical Science - February 18, 2015 Category: Journals (General) Source Type: research

Methodological flaws in the systematic review and meta-analysis on glucose metabolism disorders in patients with primary aldosteronism
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 15, 2015 Category: Journals (General) Source Type: research

The relevance of basic sciences in undergraduate medical education
Conclusions University basic sciences were found to be more predictive than school sciences in undergraduate medical performance in our institution. The increasing emphasis of basic sciences in medical practice and the declining availability of school sciences should mandate medical schools in Ireland to consider how removing basic sciences from the curriculum might impact on future applicants. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 14, 2015 Category: Journals (General) Source Type: research

Port site metastatic disease in ovarian carcinoma
Conclusion In all cases, port-site metastatic disease developed rapidly and was clinically suspected at the time of definitive surgery. We recommend that consideration be given towards removing port sites when performing cytoreductive surgery for gynaecological malignancy. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 14, 2015 Category: Journals (General) Source Type: research

Retraction Note to: Magnetic resonance imaging evaluation of intervertebral test spacers: an experimental comparison of magnesium versus titanium and carbon fiber reinforced polymers as biomaterials
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 13, 2015 Category: Journals (General) Source Type: research

Fifty Fifth Annual Meeting of the Irish Otorhinolaryngology/Head and Neck Society
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 12, 2015 Category: Journals (General) Source Type: research

Breast cancer detection among Irish BRCA1 & BRCA2 mutation carriers: a population-based study
Conclusion In this cohort of Irish BRCA1/2 mutation carriers, compliance with screening was inconsistent. There was a 30 % incidence of interval cancers occurring in women in high-risk screening. Preventive surgery may be a more effective risk reduction strategy for certain high-risk women. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 12, 2015 Category: Journals (General) Source Type: research

Attitudes of GP trainees towards the training received in urology on the GP training scheme
Conclusion This study highlights a number of concerns among GP trainees in relation to their training in urology. These issues should be addressed to ensure that the training scheme sufficiently prepares GPs to manage common urological conditions. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 12, 2015 Category: Journals (General) Source Type: research

ADHD in children: a path to free medicines
Conclusions There appears to be a significant underutilisation of the LTI scheme affording children free ADHD medication. Public and professional awareness campaigns are required to ensure families get the benefits to which they are entitled, and cost does not become a barrier to treatment adherence and improved outcomes. Leading from this, we propose suggestions for cost-effective prescribing to minimise potential cost implications. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 12, 2015 Category: Journals (General) Source Type: research

Auditory canal exostoses in Irish surfers
Conclusions This is first study of this nature in the UK or Ireland. With a 5- to 6-year lag phase for exostoses to develop, these patients are likely to become an increasing part of Otolaryngologist’s workload. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 12, 2015 Category: Journals (General) Source Type: research

An analysis of medical students’ attitude to surgical careers and pursuing intercalated research degrees
This study assesses the attitudes of medical students towards a career in surgery and their attitudes to research, especially in the context of an intercalated degree programme. Methods 615 students comprising both undergraduates and postgraduates from RCSI were surveyed. The influence of a number of factors was ranked using five-point Likert scales. Students were asked to rate the importance of research to their future careers. Results 595 (97 %) of those surveyed completed the questionnaire satisfactorily. Those interested in surgery wer...
Source: Irish Journal of Medical Science - February 5, 2015 Category: Journals (General) Source Type: research

A successful cesarean section followed with endovascular stent-graft implantation for a 36-week twin pregnancy with acute aortic dissection: a case report
Conclusion This case report illustrates the value of comprehensive multidisciplinary discussion and collaboration among different departments to make quick decisions. Endovascular stent-graft repair may be the best option for the treatment of Stanford type B aortic dissection in late pregnancy. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 3, 2015 Category: Journals (General) Source Type: research

Valproic acid-mediated inhibition of trimethyltin-induced deficits in memory and learning in the rat does not directly depend on its anti-oxidant properties
Abstract Background Trimethyltin (TMT) acts as a potent neurotoxic compound especially for the hippocampus. The effects of valproic acid (VPA) on TMT-induced learning and memory deficits were investigated. Methods The rats were divided into: (1) control, (2) TMT, (3) TMT–VPA 1, (4) TMT–VPA 5, (5) TMT–VPA 10. TMT was injected as a single dose (12 mg/kg, ip) in groups 2–5. The animals of groups 3–5 were treated by 1, 5, and 10 mg/kg of VPA for 2 weeks. Learning and memory deficits were assessed by Morris water m...
Source: Irish Journal of Medical Science - February 1, 2015 Category: Journals (General) Source Type: research

Dublin and Irish politics in the age of Charles Lucas
Conclusion Lucas’ remarkable political success stemmed from both local circumstances and his own personal qualities. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 1, 2015 Category: Journals (General) Source Type: research

Royal Academy of Medicine in Ireland and Dublin City Council Charles Lucas Tercentenary Symposium
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - February 1, 2015 Category: Journals (General) Source Type: research

The Essay on waters and other medical writings of Charles Lucas
Abstract In recent years, more attention has been given to Charles Lucas’s medical career, in its own way just as interesting and important as his better-known political campaigns. Lucas’s first concentrated period of medical activity was in the 1730s, when he had qualified as an apothecary, the second in the 1750s, following his flight from Ireland and achievement of qualifications in medicine. Having been prominently involved in the campaign which led to the 1735 drugs regulation act, in 1741 Lucas published a pamphlet, Pharmacomastix, which detailed abuses common in the apothecary’s trade and ...
Source: Irish Journal of Medical Science - January 25, 2015 Category: Journals (General) Source Type: research

Charles Lucas and medical legislation in eighteenth century Ireland
Conclusion In medical terms, Charles Lucas was man ahead of his time. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 25, 2015 Category: Journals (General) Source Type: research

Irish society of gastroentrology, summer meeting, 2014
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 24, 2015 Category: Journals (General) Source Type: research

Lucas and patriotism in mid-eighteenth century Ireland
Abstract This paper explores the extent to which Charles Lucas can be described as a typical patriot in mid-eighteenth century Ireland. The political ideas and practices of Irish patriots of the mid-eighteenth century belong to broad spectrum including opposition MPs, anti-Catholic rhetoricians and questioners of the usefulness of the penal laws, economic pamphleteers and individuals interested in recovering Ireland’s history and antiquities. Lucas was significant in that he sometimes inhabited all of these political and cultural guises, but also mobilised the Dublin public in political campaigns and was str...
Source: Irish Journal of Medical Science - January 23, 2015 Category: Journals (General) Source Type: research

4th Annual Meeting, Frontiers in Neurology, Friday 21st November 2014, Dublin, Ireland
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 22, 2015 Category: Journals (General) Source Type: research

Irish society of gastroenterology, winter meeting, 2013
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 21, 2015 Category: Journals (General) Source Type: research

The life and significance of Charles Lucas (1713–1771)
Abstract Charles Lucas (1713–1771) was one of the most controversial popular politicians to stride the Irish political stage in the eighteenth century. Though the descendant of a beneficiary of the Cromwellian plantation, Lucas’s personal inheritance was small, and he was apprenticed in his teens to an apothecary in Dublin. Lucas prospered in that capacity, both as an advocate of higher standards within the profession, and as a representative on the lower house (the common council) of Dublin Corporation. Predisposed to challenge what he perceived as abuses by vested and established interests, Lucas mad...
Source: Irish Journal of Medical Science - January 21, 2015 Category: Journals (General) Source Type: research

Report on the creation of a diabetes register and retinopathy screening outcomes in the Mid-West of Ireland
Conclusions The HSE Mid-West has over 11,000 patients on its database ready to be screened by the national programme, with the treatment of maculopathy expected to have the largest impact on resources. Although the majority of patients are already undergoing screening in the community in an ad hoc fashion, the rates of sight-threatening retinopathy encountered highlight the timeliness of the full implementation of the national programme. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 17, 2015 Category: Journals (General) Source Type: research

Management of the axilla: has Z0011 had an impact?
Conclusions There has been a change in clinical practice since the publication of the Z0011 trial, illustrated by a decrease in the rate of axillary clearance in node-positive breast cancers. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 17, 2015 Category: Journals (General) Source Type: research

A preserved stratified pattern of the bowel wall 1 year after major surgery does not influence the surgical recurrence of Crohn’s disease
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 13, 2015 Category: Journals (General) Source Type: research

Securing the future of interventional radiology with lessons from the past
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 13, 2015 Category: Journals (General) Source Type: research

On the fate of particles liberated from hydroxyapatite coatings in vivo
Conclusions This review summarises and discusses each of these factors and concludes that HA is a safe biomimetic material to use as a coating and does not cause any problems in particulate form if liberated as debris from an orthopaedic implant. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 10, 2015 Category: Journals (General) Source Type: research

Clinical significance of lesser occipital nerve preservation during micro-vascular decompression for hemi-facial spasm
Conclusions For HFS patients who attempted to receive MVD, LON preservation could reduce the incidence of sensory disturbance around the operative region, despite causing extend operation time. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 6, 2015 Category: Journals (General) Source Type: research

Re: cross-sectional audit on the relevance of Elevated National Early Warning Score in medical patients at a Model 2 hospital in Ireland
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 6, 2015 Category: Journals (General) Source Type: research

Management of paediatric acute appendicitis in the general hospital setting: a national survey of preferred surgical technique
This study has shown wide variability amongst consultant general surgeons when considering open versus laparoscopic appendicectomy in children under 12 years. Restricted access to specialist paediatric laparoscopic equipment, combined with declining exposure to paediatric surgical training, may continue to limit the numbers of paediatric laparoscopic appendicectomies performed in the general setting. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - January 2, 2015 Category: Journals (General) Source Type: research