Incidence of neurological manifestations and complications in patients with COVID-19 infection: a propensity score matching analysis
ConclusionsIn the Thai COVID-19 patient cohort, roughly 22% experienced neurological complications, with severe infection standing out as a major risk factor. This underscores the importance of closely monitoring neurological symptoms in COVID-19 patients. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 12, 2023 Category: General Medicine Source Type: research

MicroRNA-582-3p knockdown alleviates non-alcoholic steatohepatitis by altering the gut microbiota composition and moderating TMBIM1
ConclusionsThis present study suggests that miR-582-3p promotes the progression of NASH. Knockdown of miR-582-3p may alleviate NASH by altering the gut microbiota composition and moderating TMBIM1. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 12, 2023 Category: General Medicine Source Type: research

Improving the clinical monitoring of extrapyramidal symptoms: a local quality improvement project
ConclusionDocumentation of EPS monitoring improved significantly across several settings affiliated with a Dublin North City MHS following the systematic adoption of the Extrapyramidal Symptom Scale (EPSS) and clinician education regarding its use. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 8, 2023 Category: General Medicine Source Type: research

The effect Of vascular related CeRNA genes and corresponding imaging biomarkers on survival in lower grade glioma
ConclusionsUnder different IDH1 mutations, lncRNA-dominated vascular-related ceRNA regulatory genes were the first differentially expressed subset of each group, and could be used as an effective risk factor affecting the survival of LGG. The image characteristics of LGG was an ideal image gene marker. It was a reliable imaging biological marker which can truly reflect the pathophysiological characteristics of glioma. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 6, 2023 Category: General Medicine Source Type: research

A systematic review and meta-analysis assessing the use of tranexamic acid (TXA) in acute gastrointestinal bleeding
ConclusionTXA does not reduce mortality in patients with acute upper or lower gastrointestinal bleeding and may confer an increased risk of seizures. The authors do not recommend the use of TXA in acute gastrointestinal bleeding. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 4, 2023 Category: General Medicine Source Type: research

Aural microsuction: an analysis of post-procedure patient safety incidents
Conclusions and significanceWhilst aural microsuction is universally accepted to be a low-risk procedure, subsequent serious morbidity can occur. Implementation and awareness of local safety policies are imperative to avoid post-procedure injury. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - October 4, 2023 Category: General Medicine Source Type: research

A national survey of clubs medical provision and facilities in BUCS American Football 2019 –2020
ConclusionsThese findings provide key information on the status of medical provision, facilities and protocols in BUCS BAF. Data reveals a lack of consistent medical personnel, particularly at training and away games, and training in emergency care. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 27, 2023 Category: General Medicine Source Type: research

Diagnostic value of molecular approach in screening for fragile X premutation cases
ConclusionMolecular diagnostic assay including (MS-PCR) and (qRT-PCR) proved to be a sensitive and rapid screening tool for the detection of premutation cases. Furthermore, the presence of positive correlation between FMR1 mRNA expression levels with CGG repeats in premutation cases could serve as a potential diagnostic marker. Application of these diagnostic tools on larger number clinically suspected cases is recommended. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 27, 2023 Category: General Medicine Source Type: research

The effect of full blood count and cardiac biomarkers on prognosis in carbon monoxide poisoning in children
In this study, cardiac biomarkers, blood parameters, electrocardiography (ECG), and echocardiography were investigated in children with carbon monoxide (CO) poisoning, and the diagnostic value of these parameters was investigated.MethodsThe demographical, clinical, and laboratory data of children aged 0 –18 years who were admitted to the pediatric emergency department due to CO poisoning between January 2019 and January 2022 were retrospectively scanned from medical records. The patients were divided into two groups as troponin-I positive and troponin-I negative.ResultsThere were 107 children aged 0 –18 years (averag...
Source: Irish Journal of Medical Science - September 27, 2023 Category: General Medicine Source Type: research

Correction to: Impacts of protective face masks on ocular surface symptoms among healthcare professionals during the COVID ‑19 pandemic
(Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 27, 2023 Category: General Medicine Source Type: research

Long-term renal function following radical cystectomy and ileal conduit creation
ConclusionsPatients with RC are at risk of progressive kidney function deterioration and elevated mortality and the main risk factors associated were age and preoperative eGFR. Regular monitoring of kidney function will permit early diagnosis and treatment. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 24, 2023 Category: General Medicine Source Type: research

Specialist cancer hospital-based smoking cessation service provision in Ireland
ConclusionThe recently launched National Clinical Guideline for smoking cessation provides the template for all hospitals to ensure health services are in a position to contribute to Ireland ’s tobacco endgame goal. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 23, 2023 Category: General Medicine Source Type: research

Cardiac myxomas: causes, presentations, diagnosis, and management
The objective of this narrative review wa s to study the variable clinical presentations of cardiac myxoma, its detection and diagnosis involving multiple modalities like genetic and hematological testing, echocardiography, CT, and MRI, of which transoesophageal echocardiogram shows excellent precision with a 90% to 96% accuracy in diagnosi ng CM. Individuals with the Carney complex are prone to such neoplasia. Cardiac myxomas are challenging to diagnose due to the ambiguity of their differential with thrombi. Myxomas can also be diagnosed by tumor markers like interleukin-6 and endothelial growth factors. The management o...
Source: Irish Journal of Medical Science - September 22, 2023 Category: General Medicine Source Type: research

Non-criteria autoantibodies in antiphospholipid syndrome may be associated with underlying disease activity
ConclusionSystemic lupus erythematosus (SLE) is the most commonly associated disease with APS, being present in approximately 35% of cases  [1]. Since the majority of the patient group in our study had APS that was secondary to SLE, non-criteria antibody positivity may be linked to the immunological activity of SLE. Large multicenter studies are necessary to investigate the clinical significance of isolated/combined positivity for criterion/non-criteria aPLs. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 22, 2023 Category: General Medicine Source Type: research

Survey of Laboratory Medicine ’s national response to the HSE cyberattack in the Republic of Ireland
ConclusionThe cyberattack burdened the HSE and laboratories at a time when healthcare staffs were coming to terms with the impact of the COVID-19 pandemic. Despite this, the survey confirms the agility of laboratory staff in meeting the demands placed on it during this time. (Source: Irish Journal of Medical Science)
Source: Irish Journal of Medical Science - September 22, 2023 Category: General Medicine Source Type: research