International Journal of Radiation Oncology * Biology * Physics This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Results of an Artificial Intelligence –Based Image Review System to Detect Patient Misalignment Errors in a Multi-institutional Database of Cone Beam Computed Tomography–Guided Radiation Therapy
Present knowledge of patient setup and alignment errors in image guided radiation therapy (IGRT) relies on voluntary reporting, which is thought to underestimate error frequencies. A manual retrospective patient-setup misalignment error search is infeasible owing to the bulk of cases to be reviewed. We applied a deep learning –based misalignment error detection algorithm (EDA) to perform a fully automated retrospective error search of clinical IGRT databases and determine an absolute gross patient misalignment error rate. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 11, 2024 Category: Radiology Authors: Dishane C. Luximon, Jack Neylon, Timothy Ritter, Nzhde Agazaryan, John V. Hegde, Michael L. Steinberg, Daniel A. Low, James M. Lamb Tags: PHYSICS CONTRIBUTION Source Type: research

Results of an AI-Based Image Review System to Detect Patient Misalignment Errors in a Multi-Institutional Database of CBCT-Guided Radiotherapy Treatments
Present knowledge of patient setup and alignment errors in image-guided radiotherapy (IGRT) relies on voluntary reporting, which is thought to underestimate error frequencies. A manual retrospective patient-setup misalignment error search is infeasible due to the bulk of cases to be reviewed. We applied a deep learning-based misalignment error detection algorithm (EDA) to perform a fully-automated retrospective error search of clinical IGRT databases and determine an absolute gross patient misalignment error rate. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 11, 2024 Category: Radiology Authors: Dishane C. Luximon, Jack Neylon, Timothy Ritter, Nzhde Agazaryan, John V. Hegde, Michael L. Steinberg, Daniel A. Low, James M. Lamb Tags: Physics Contribution Source Type: research

Neutron capture enhances dose and reduces cancer cell viability in and out of beam during helium and carbon ion therapy
Neutron Capture Enhanced Particle Therapy (NCEPT) is a proposed augmentation of charged particle therapy which exploits thermal neutrons generated internally, within the treatment volume via nuclear fragmentation, to deliver a biochemically targeted radiation dose to cancer cells. This work is the first experimental demonstration of NCEPT, performed using both carbon and helium ion beams with two different targeted neutron capture agents (NCAs). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 11, 2024 Category: Radiology Authors: Nicholas Howell, Ryan J. Middleton, Frederic Sierro, Naomi A. Wyatt, Andrew Chacon, Benjamin H. Fraser, Keith R. Bambery, Elle Livio, Christopher Dobie, Joseph J. Bevitt, Justin Davies, Anthony Dosseto, Daniel R. Franklin, Ulf Garbe, Susanna Guatelli, Ryo Tags: Biology Contribution Source Type: research

Neurologic Changes Induced by Whole-Brain Synchrotron Microbeam Irradiation: 10-Month Behavioral and Veterinary Follow-Up
In this study, we evaluated normal tissue toxicity of whole-brain microbeam irradiation (MBI) versus that of a conventional hospital broad beam (hBB). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: Laura Eling, Camille Verry, Jacques Balosso, Isabelle Flandin, Samy Kefs, Audrey Bouchet, Jean Fran çois Adam, Jean Albert Laissue, Raphael Serduc Tags: BIOLOGY CONTRIBUTION Source Type: research

Oxygen Enhancement Ratio –Weighted Dose Quantitatively Describes Acute Skin Toxicity Variations in Mice After Pencil Beam Scanning Proton FLASH Irradiation With Changing Doses and Time Structures
The aim of this work was to investigate the ability of a biological oxygen enhancement ratio –weighted dose, DOER, to describe acute skin toxicity variations observed in mice after proton pencil beam scanning irradiations with changing doses and beam time structures. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: Per Rugaard Poulsen, Jacob Graversen Johansen, Mateusz Krzysztof Sitarz, Eleni Kanouta, Line Kristensen, Cai Grau, Brita Singers S ørensen Tags: PHYSICS CONTRIBUTION Source Type: research

Accuracy and Clinical Impact of Persistent Disease Diagnosed on Diffusion-Weighted Imaging and Accuracy of Pelvic Nodal Assessment on Magnetic Resonance Imaging for Squamous Cell Carcinoma of the Anus in the 6-Month Interval Post Chemoradiotherapy
To evaluate the diagnostic performance of diffusion-weighted imaging (DWI) in the 6-month interval post chemoradiation therapy (CRT) in determining persistent disease and whether persistent diffusion restriction on DWI at 6 months is associated with overall survival; and secondarily, to investigate the accuracy of pelvic lymph node assessment on T2-weighted imaging and DWI in the 6-month interval post CRT, in patients with squamous cell carcinoma of the anus. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: Maria Clara Fernandes, Charlotte Charbel, Paul B. Romesser, Burcin Agridag Ucpinar, Maria El Homsi, Onur Yildirim, James L. Fuqua, Lee A. Rodriguez, Junting Zheng, Marinela Capanu, Marc J. Gollub, Natally Horvat Tags: CLINICAL INVESTIGATION Source Type: research

Cluster-Based Toxicity Estimation of Osteoradionecrosis via Unsupervised Machine Learning: Moving Beyond Single Dose-Parameter Normal Tissue Complication Probability by Using Whole Dose-Volume Histograms for Cohort Risk Stratification
Given the limitations of extant models for normal tissue complication probability estimation for osteoradionecrosis (ORN) of the mandible, the purpose of this study was to enrich statistical inference by exploiting structural properties of data and provide a clinically reliable model for ORN risk evaluation through an unsupervised-learning analysis that incorporates the whole radiation dose distribution on the mandible. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: Seyedmohammadhossein Hosseinian, Mehdi Hemmati, Cem Dede, Travis C. Salzillo, Lisanne V. van Dijk, Abdallah S.R. Mohamed, Stephen Y. Lai, Andrew J. Schaefer, Clifton D. Fuller, Rice/MD Anderson Center for Operations Research in Cancer (CORC) and MD Anders Tags: Physics Contribution Source Type: research

Delays in cervical cancer treatment initiation for patients living with or without HIV in Botswana: An observational cohort analysis (2015-2019)
Present delays in treatment initiation of chemoradiation or radiation alone for patients with advanced stage cervical cancer in Botswana. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: Jessica George, Shawna Tuli, Palak P. Patel, Barati Monare, Doreen Ramogola-Masire, Lisa Bazzett-Matabele, Memory Bvochora-Nsingo, Sebathu Chiyapo, Tlotlo Ralefala, Peter Vuylsteke, Katharine A. Rendle, Surbhi Grover Tags: Clinical Investigation Source Type: research

Perception and Utilization of Cannabinoids in Patients Undergoing Radiation Treatment: Our Patients Are Curious
Limited studies have described the utilization of cannabinoids among cancer patients. This survey study aimed to characterize utilization patterns and perceptions of cannabinoid use for treatment-related side effects among patients receiving radiation treatment. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: Andrew Tam, Jennifer Novak, Colton Ladbury, Tariq Abuali, Matthew Loscalzo, Virginia Sun, Arya Amini Tags: Brief Report Source Type: research

Oxygen enhancement ratio weighted dose quantitatively describes acute skin toxicity variations in mice after pencil beam scanning proton FLASH irradiation with changing doses and time structures
To investigate the ability of a biological oxygen enhancement ratio weighted dose, DOER, to describe acute skin toxicity variations observed in mice after proton pencil beam scanning (PBS) irradiations with changing doses and beam time structures. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: Per Rugaard Poulsen, Jacob Graversen Johansen, Mateusz Krzysztof Sitarz, Eleni Kanouta, Line Kristensen, Cai Grau, Brita Singers S ørensen Tags: Physics Contribution Source Type: research

Neurologic changes induced by whole-brain synchrotron microbeam irradiation: 10 months behavioral and veterinary follow-up
In this study, we evaluated normal tissue toxicity of whole-brain microbeam irradiation (MBI) versus that of a conventional, hospital broad beam (hBB). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: L. Eling, C. Verry, J. Balosso, I. Flandin, S. Kefs, A. Bouchet, J.F. Adam, J.A. Laissue, R. Serduc Tags: Biology Contribution Source Type: research

Clinical impact of restaging pelvic DWI-MRI and pelvic nodal assessment for squamous cell carcinoma of the anus in the 6-month interval post chemoradiotherapy
To evaluate the diagnostic performance of diffusion-weighted imaging (DWI) in determining persistent disease and whether persistent diffusion restriction within the anal canal is associated with overall survival, and investigate the accuracy of pelvic lymph node (LN) assessment on 6-month restaging MRI in patients with squamous cell carcinoma of the anus (SCCA). (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 8, 2024 Category: Radiology Authors: Maria Clara Fernandes, Charlotte Charbel, Paul B. Romesser, Burcin Agridag Ucpinar, Maria El Homsi, Onur Yildirim, James L. Fuqua, Lee A. Rodriguez, Junting Zheng, Marinela Capanu, Marc J. Gollub, Natally Horvat Tags: Clinical Investigation Source Type: research

Tumor Contact with Internal Mammary Perforator Vessels as Risk Factor for Gross Internal Mammary Lymph Node Involvement in Breast Cancer Patients
The identification of internal mammary lymph node metastases and the assessment of associated risk factors are crucial for adjuvant regional lymph node irradiation in breast cancer patients. The current study aims to investigate if tumor contact with internal mammary perforator vessels is associated with gross internal mammary lymph node involvement. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 6, 2024 Category: Radiology Authors: Sophie T. Behzadi, Rebecca Moser, Sophia Kiesl, Jana Nano, Jan C. Peeken, Julius C. Fischer, Eva M. Fallenberg, Thomas Huber, Bernhard Haller, Evelyn Klein, Marion Kiechle, Stephanie E. Combs, Kai J. Borm Source Type: research

Quantifying Regional Radiation-Induced Lung Injury in Patients Using Hyperpolarized 129Xe Gas Exchange Magnetic Resonance Imaging
Radiation-induced lung injury has been shown to alter regional ventilation and perfusion in the lung. However, changes in regional pulmonary gas exchange have not previously been measured. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 4, 2024 Category: Radiology Authors: Leith J. Rankine, Junlan Lu, Ziyi Wang, Christopher R. Kelsey, Lawrence B. Marks, Shiva K. Das, Bastiaan Driehuys Tags: PHYSICS CONTRIBUTION Source Type: research

Potential Role of Lymphocyte CD44 in Determining Treatment Selection Between Stereotactic Body Radiation Therapy and Surgery for Early-Stage Non-Small Cell Lung Cancer
Stereotactic body radiation therapy (SBRT) versus surgery for operable early-stage non-small cell lung cancer (ES-NSCLC) remains highly debated. Herein, we used spatial proteomics to identify whether any molecular biomarker(s) associate with the efficacy of either modality, in efforts to optimize treatment selection between surgery and SBRT for this population. (Source: International Journal of Radiation Oncology * Biology * Physics)
Source: International Journal of Radiation Oncology * Biology * Physics - March 4, 2024 Category: Radiology Authors: Weiwei Yan, Ziyuan Ren, Xi Chen, Ran Zhang, Juncai Lv, Vivek Verma, Meng Wu, Dawei Chen, Jinming Yu Tags: Clinical Investigation Source Type: research