Prevalence of fever of unidentified aetiology in East African adolescents and adults: a systematic review and meta-analysis
ConclusionsOur study provides evidence that almost two-thirds of adolescent and adult febrile patients attending health care facilities in East Africa might receive inappropriate treatments due to unidentified potential life-threatening fever aetiology. Hence, we call for a comprehensive fever syndromic surveillance to broaden a consequential differential diagnosis of syndromic fever and to considerably improve the course of patients ’ disease and treatment outcomes. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 25, 2023 Category: Infectious Diseases Source Type: research

Global prevalence of drug-resistant tuberculosis: a systematic review and meta-analysis
ConclusionsThe global prevalence of drug-resistant tuberculosis was found to be very high, thus health authorities should consider ways to control and manage the disease to prevent a wider spread of tuberculosis and potentially subsequent deaths. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 25, 2023 Category: Infectious Diseases Source Type: research

Performance of the procedure for ultra-rapid extraction and loop-mediated isothermal amplification (PURE-LAMP) method to detect malaria in Haiti
ConclusionsThis study confirmed the high performance of the PURE-LAMP method to detectPlasmodium infection with dried blood spots and recommends its use in targeted mass screening and treatment activities in low endemic areas of malaria. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 22, 2023 Category: Infectious Diseases Source Type: research

Long-distance spread of Tembusu virus, and its dispersal in local mosquitoes and domestic poultry in Chongming Island, China
ConclusionsWe speculate that the TMUV was imported to Chongming Island through long-distance spreading by migratory birds from Southeast Asia, followed by spill over and transmission in mosquitoes and domestic avian species, threatening the local domestic poultry. In addition, the expansion and prevalence of insect-specific flaviviruses and its simultaneous circulation with mosquito-borne virus are worthy of close attention and further study. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 22, 2023 Category: Infectious Diseases Source Type: research

The prevalence of soil transmitted helminths and its influential factors in Shandong Province, China: an analysis of surveillance data from 2016 to 2020
ConclusionsThere is a remarkable declining in STHs prevalence in Shandong Province from 2016 to 2020. However, the prevalence rates of STHs especiallyT. trichiura in the southern and eastern regions were still high, and the elderly were more susceptible to be infected with STHs owning to their low awareness level of STHS-related prevention knowledge and high adoption rate of dangerous production and living behaviours. Integrated approaches of health education, environment improvement and behaviour change should be strengthened to obtain a further reduction of STHs prevalence in China. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 22, 2023 Category: Infectious Diseases Source Type: research

Climate change and infectious disease: a review of evidence and research trends
ConclusionsFuture research lines on climate change and infectious diseases should considered diseases of direct transmission (non-vector-borne) and more research effort in the tropics. Inclusion of local research in low- and middle-income countries was generally neglected. Research on climate change and infectious disease has failed to be socially inclusive, geographically balanced, and broad in terms of the disease systems studied, limiting our capacities to better understand the actual effects of climate change on health.Graphical abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 16, 2023 Category: Infectious Diseases Source Type: research

One Health: navigating plague in Madagascar amidst COVID-19
ConclusionsDespite being endemic to Madagascar, the outbreak ’s pace is unparalleled, and it may spread to non-endemic areas. The utilization of a One Health strategy that encompasses various disciplines is crucial for minimizing catastrophe risk, antibiotic resistance, and outbreak readiness. Collaboration across sectors and proper planning ensures efficie nt and consistent communication, risk management, and credibility during disease outbreaks.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 16, 2023 Category: Infectious Diseases Source Type: research

High-risk spatiotemporal patterns of cutaneous leishmaniasis: a nationwide study in Iran from 2011 to 2020
ConclusionsOur study has revealed significant regional, temporal, and spatiotemporal patterns of CL distribution in Iran. Over the years, there have been multiple shifts in spatiotemporal clusters, encompassing many different parts of the country from 2011 to 2020. The results reveal the formation of clusters across counties that cover certain parts of provinces, indicating the importance of conducting spatiotemporal analyses at the county level for studies that encompass entire countries. Such analyses, at a finer geographical scale, such as county level, might provide more precise results than analyses at the scale of th...
Source: Infectious Diseases of Poverty - May 15, 2023 Category: Infectious Diseases Source Type: research

Mosquito densovirus significantly reduces the vector susceptibility to dengue virus serotype 2 in Aedes albopictus mosquitoes (Diptera: Culicidae)
ConclusionsMDVs is widespread in natural mosquito populations, and replication of DENV-2 is suppressed in MDV-infectedAe. albopictus, thus reducing vector susceptibility to DENV-2. Our study supports the hypothesis that MDVs may contribute to reducing transmission of DENV and provides an alternative strategy for mosquito-transmitted disease control.Graphical abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 9, 2023 Category: Infectious Diseases Source Type: research

Transmission risk of Oropouche fever across the Americas
ConclusionsHotspots of OROV transmission risk were detected along the tropics of South America. Vegetation loss might be a driver of Oropouche fever emergence. Modeling based on hypervolumes in spatial epidemiology might be considered an exploratory tool for analyzing data-limited emerging infectious diseases for which little understanding exists on their sylvatic cycles. OROV transmission risk maps can be used to improve surveillance, investigate OROV ecology and epidemiology, and inform early detection. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 6, 2023 Category: Infectious Diseases Source Type: research

Genetic structure of Aedes albopictus (Diptera: Culicidae) populations in China and relationship with the knockdown resistance mutations
ConclusionsThe degree of genetic differentiation amongAe. albopictus populations in China was low. These populations were divided into three gene pools, in which the northern and eastern pools are relatively homogeneous, while the southern gene pool is heterogeneous. The possible correlation between its genetic variations andkdr mutations is also noteworthy.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 5, 2023 Category: Infectious Diseases Source Type: research

Three Gorges Dam: the changing trend of snail density in the Yangtze River basin between 1990 and 2019
ConclusionsSnail density exhibited a fluctuating downward trend in the Yangtze River basin. In the downstream area, the operation of TGD accelerated the decline of snail density during the first decade period, then snail density fluctuated at a relatively low level. There still exists local areas with a high snail density. Long-term control and monitoring of snails need to be insisted on and strengthened.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - April 28, 2023 Category: Infectious Diseases Source Type: research

Prevalence and risk distribution of schistosomiasis among adults in Madagascar: a cross-sectional study
ConclusionsOur findings provide evidence that adults are a high-risk group for schistosomiasis. Our data suggests that, for ensuring basic health as a human right, current public health strategies for schistosomiasis prevention and control need to be re-addressed towards more context specific, holistic and integrated approaches. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - April 25, 2023 Category: Infectious Diseases Source Type: research

Increased interleukin-6 is associated with long COVID-19: a systematic review and meta-analysis
ConclusionsThis study showed that increased IL-6 correlates with long COVID-19. Such an informative revelation suggests IL-6 as a basic determinant to predict long COVID-19 or at least inform on the “early stage” of long COVID-19. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - April 24, 2023 Category: Infectious Diseases Source Type: research

Public health implications of Yersinia enterocolitica investigation: an ecological modeling and molecular epidemiology study
ConclusionsThe data indicated geographical variations in the distribution of STs and CTs ofY. enterocolitica isolates in Ningxia. Our work offered the first evidence that the pathogenicity of isolates was directly related to fluctuations in temperature and precipitation of the environment. CgMLST typing strategies showed that the isolates were transmitted to the population via pigs and food. Therefore, strengthening health surveillance on pig farms in high-risk areas and focusing on testing food of pig origin are optional strategies to prevent disease outbreaks. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - April 21, 2023 Category: Infectious Diseases Source Type: research