Impact of 1,7-malaria reactive community-based testing and response (1,7-mRCTR) approach on malaria prevalence in Tanzania
ConclusionsThe 1,7-mRCTR approach reduced malaria prevalence. Despite implementation interruptions due to the COVID-19 pandemic and supply chain challenges, the study provided novel evidence on the effectiveness of community-based reactive approaches in moderate- to high-endemicity areas and demonstrated the potential of South-South cooperation in tackling global health challenges.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 18, 2023 Category: Infectious Diseases Source Type: research
New clinical application prospects of artemisinin and its derivatives: a scoping review
ConclusionsRecent clinical studies suggest that artemisinin and its derivatives may be safe and effective candidates for anti-tumor, anti-parasitic, anti-inflammatory and dermatological drugs. More phase II/III clinical trials of artemisinin and its derivatives on antiviral effects are needed.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 11, 2023 Category: Infectious Diseases Source Type: research
The coverage and challenges of increasing uptake of non-National Immunization Program vaccines in China: a scoping review
ConclusionsThere is an urgent need to increase coverage of non-NIP vaccines and reduce disparities in access to these vaccines across regions. Concerted efforts from the government, the public, and society are required to tackle the barriers and challenges identified in this study, both on the demand and supply side, to ensure everybody has equal access to life-saving vaccines in China. Particularly, the government should take a prudent approach to gradually incorporate non-NIP vaccines into the NIP step by step, and make a prioritizing strategy based on key factors such as disease burden, financial resources, and market r...
Source: Infectious Diseases of Poverty - December 8, 2023 Category: Infectious Diseases Source Type: research
A potential transition from a concentrated to a generalized HIV epidemic: the case of Madagascar
ConclusionsThese results suggest that Madagascar may be experiencing a silent transition from a concentrated to a generalized HIV epidemic. This case-study model could help to understand how this HIV epidemic transition occurs.Graphical abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 7, 2023 Category: Infectious Diseases Source Type: research
Evaluating active leprosy case identification methods in six districts of Nepal
ConclusionsThe most effective case identification approach here is contact tracing, followed by house-to-house visits in vulnerable populations and screening in prisons, although house-to-house visits are cheaper. The findings suggest that hidden cases, recent transmission, and late diagnosis in the community exist and highlight the importance of early case detection. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 6, 2023 Category: Infectious Diseases Source Type: research
Five years of post-validation surveillance of lymphatic filariasis in Thailand
ConclusionsIn 2022, after 5 years of PVS, Thailand re-surveyed 41% of its previously endemic IUs and demonstrated ongoing transmission in only one province of Narathiwat, where Mf prevalence is below the WHO provisional transmission threshold of 1%. This study highlights the importance of continued disease surveillance measu res and vigilance among health care providers in LF receptive areas.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 6, 2023 Category: Infectious Diseases Source Type: research
13-Valent pneumococcal conjugate vaccines vaccination innovative strategy in Weifang City, China: a case study
AbstractThe World Health Organization (WHO) prioritizes pneumococcal disease as a vaccine-preventable disease and recommends the inclusion of pneumococcal conjugate vaccines (PCV) in national immunization programs worldwide. However, PCV is not included in the National Immunization Program in China and has low vaccination coverage due to its high cost. To address this, Weifang City implemented an innovative strategy for a 13-valent PCV (PCV13) on June 1, 2021. This strategy aimed to provide one dose of PCV13 free of charge for children aged 6 months to 2 years in registered households and to adopt a commercial insurance...
Source: Infectious Diseases of Poverty - December 1, 2023 Category: Infectious Diseases Source Type: research
Introduction of invasive mosquito species into Europe and prospects for arbovirus transmission and vector control in an era of globalization
ConclusionsClimate change and globalization resulting in the increased establishment of invasive mosquitoes in particular of the Asian tiger mosquitoAe. albopictus in Europe within the last 30 years and increasing outbreaks of infections by mosquito-borne viruses warrants intensification of research and monitoring. Further, effective future mosquito control programs require increase in intense community and private participation, applying physical, chemical, biological, and genetical co ntrol activities. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 30, 2023 Category: Infectious Diseases Source Type: research
Influence of urbanization on schistosomiasis infection risk in Anhui Province based on sixteen year's longitudinal surveillance data: a spatio-temporal modelling study
ConclusionsThe influence of urbanization on schistosomiasis infection has spatio-temporal heterogeneous. The urbanization does reduce the risk of schistosomiasis infection to some extend, but the strength of this influence decreases with increasing urbanization. Additionally, the effect of urbanization on schistosomiasis infection risk was greater than previous reported natural environmental factors. This study provides scientific basis for understanding the influence of urbanization on schistosomiasis, and also provides the feasible research methods for other similar studies to answer the issue about the impact of urbaniz...
Source: Infectious Diseases of Poverty - November 29, 2023 Category: Infectious Diseases Source Type: research
Chromosome-scale genome of the human blood fluke Schistosoma mekongi and its implications for public health
ConclusionsThis study delivers a high-quality, chromosome-scale reference genome ofS. mekongi, enhancing our understanding of the divergence and evolution ofSchistosoma. The molecular research conducted here also plays a pivotal role in drug discovery and vaccine development. Furthermore, our work greatly advances the understanding of host-parasite interactions, providing crucial insights for schistosomiasis intervention strategies.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 28, 2023 Category: Infectious Diseases Source Type: research
Accelerating Pneumococcal Conjugate Vaccine introductions in Indonesia: key learnings from 2017 to 2022
AbstractDespite high pneumococcal disease and economic burden in Indonesia and interest to introduce pneumococcal conjugate vaccine (PCV), there were challenges in establishing a comprehensive strategy to accelerate and enable the introduction in country in the early 2010s. Starting in 2017, Clinton Health Access Initiative and partners supported the government of Indonesia with evidence-based decision-making and implementation support for introducing PCV into the routine immunization program. Indonesia has since accelerated PCV roll out, with nationwide reach achieved in 2022. On the path to PCV introduction, several ...
Source: Infectious Diseases of Poverty - November 28, 2023 Category: Infectious Diseases Source Type: research
Schistosomiasis control in Senegal: results from community data analysis for optimizing preventive chemotherapy intervention with praziquantel
ConclusionsThe analysis to disaggregate data from district level to community level using the WHO/AFRO schistosomiasis sub-district data optimization tool provide an update of schistosomiasis endemicity at community level. This study has allowed to better target schistosomiasis interventions, optimize use of available PZQ and exposed data gaps. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 27, 2023 Category: Infectious Diseases Source Type: research
Gut microbiota in parasite-transmitting gastropods
ConclusionsThis review comprehensively summarizes the current knowledge on the composition, potential function, influencing factors, potential applications, limitations, and challenges of gut microbiomes in gastropods, with a specific emphasis on parasite-transmitting gastropods. These findings provide important insights for future studies aiming to understand the potential role of gastropod gut microbiota in controlling snail populations and snail-borne diseases.Graphical abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 24, 2023 Category: Infectious Diseases Source Type: research
Social protection as a right of people affected by tuberculosis: a scoping review and conceptual framework
ConclusionsOur findings identify social protection measures as a right for people affected by tuberculosis and have the potential to guide the development of evidence-based social and health policies through collaboration between tuberculosis control programs and governmental entities. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 22, 2023 Category: Infectious Diseases Source Type: research
Accuracy of a new rapid diagnostic test for urinary antigen detection and assessment of drug treatment in opisthorchiasis
ConclusionsThe urinary OV-RDT test has high potential as a new tool for screening and evaluating treatment outcomes in opisthorchiasis. The ease of sample collection and simplicity of urinary OV-RDT may facilitate mass screening, control and elimination of opisthorchiasis, thereby contributing to a reduction in the disease burden in Southeast Asia.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - November 21, 2023 Category: Infectious Diseases Source Type: research
