Optimisation of the DNA dipstick as a rapid extraction method for Schistosoma japonicum in infected mice samples and spiked human clinical samples
ConclusionsThe DNA dipstick combined with LAMP has huge potential in providing cost-effective, simple and accurate detection of schistosomiasis infection in endemic regions. This will allow for rapid treatment, tracking outbreaks —such as occur after typhoons, leading to better health outcomes and contributing to control and eventual elimination of schistosomiasis. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - August 7, 2023 Category: Infectious Diseases Source Type: research
Tackling global health security by building an academic community for One Health action
ConclusionsThe proposed academic community for One Health action is a crucial step towards enhancing communication, coordination, collaboration, and capacity building for the implementation of One Health. By bringing eminent global experts together, the academic community possesses the potential to generate scientific evidence and provide advice to local governments and international organizations, enabling the pursuit of common goals, collaborative policies, and solutions to misaligned interests.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - August 3, 2023 Category: Infectious Diseases Source Type: research
Correction: Successful treatment with doxycycline monotherapy for human infection with Babesia venatorum (Babesiidae, Sporozoa) in China: a case report and proposal for a clinical regimen
(Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - July 27, 2023 Category: Infectious Diseases Source Type: research
Dynamic RNA profiles in the small intestinal epithelia of cats after Toxoplasma gondii infection
ConclusionsThis study is the first to reveal the expression profiles of circRNAs, lncRNAs and mRNAs in the cat small intestine followingT. gondii infection and will facilitate the elucidation of the role of ncRNAs in the pathogenesis ofT. gondii infection in its definitive host, thereby facilitating the development of novel intervention strategies againstT. gondii infection in humans and animals.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - July 25, 2023 Category: Infectious Diseases Source Type: research
Successful treatment with doxycycline monotherapy for human infection with Babesia venatorum (Babesiidae, Sporozoa) in China: a case report and proposal for a clinical regimen
ConclusionsWe have reported a clinical case of successful doxycycline monotherapy for human babesiosis caused byB. venatorum, which provides an optional medical intervention for human babesiosis.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - July 13, 2023 Category: Infectious Diseases Source Type: research
Molecular epidemiology of hepatitis C virus genotypes in different geographical regions of Chinese mainland and a phylogenetic analysis
ConclusionsHCV subtypes 1b and 2a remained the most common subtypes in Chinese mainland, and their proportions decreased over the past years, while the proportions of genotypes 3 and 6 increased. Our investigation provided an accurate epidemiological picture of the circulating viral strains in Chinese mainland, contributing to the prevention, diagnosis and treatment of HCV infection.Trial registration: Not applicable. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - July 10, 2023 Category: Infectious Diseases Source Type: research
Cost of treatment support for multidrug-resistant tuberculosis using patient-centred approaches in Ethiopia: a model-based method
ConclusionOur findings show that patient-centred and hybrid strategies for delivering MDR-TB treatment cost less than standard-of-care and provide critical evidence that there is scope for such strategies to be implemented in routine care. These results should be used inform country-level decisions on how MDR-TB is delivered and also the design of future implementation trials.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - July 7, 2023 Category: Infectious Diseases Source Type: research
Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study
ConclusionsCounterintuitively, the crude odds for concomitant STIs was lower in HIV-positive than in HIV-negative women. The change of magnitude from the crude to adjustedOR is indicative for a differential sexual risk factor profile among HIV-positive and HIV-negative women in this population. This might potentially be explained by the availability of sexual health care counselling for HIV-positive women within the framework of the national HIV control programme, while no such similar overall service exists for HIV-negative women. This highlights the importance of easy access to sexual healthcare education programmes for ...
Source: Infectious Diseases of Poverty - July 6, 2023 Category: Infectious Diseases Source Type: research
Seasonal malaria chemoprevention in Africa and China ’s upgraded role as a contributor: a scoping review
ConclusionsA combination of necessary preventive and curative activities may prove beneficial both for targeted populations and for health system strengthening in the long run. More actions are entailed to promote the partnership and China can be one of the main contributors with various roles. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - July 5, 2023 Category: Infectious Diseases Source Type: research
Comparative study on epidemiological and etiological characteristics of patients with acute diarrhea with febrile or non-febrile symptoms in China
ConclusionsThere are significant discrepancy of the infected enteric pathogens in patients with acute diarrhea with fever between age groups, and it is valuable for priority detection of NTS and rotavirus A in patients with children < 5 years old and NTS and DEC in adult patients. The results may be useful in identifying dominant pathogen candidates for the application of diagnostic assays and prevention control.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - July 4, 2023 Category: Infectious Diseases Source Type: research
Intestinal helminth infections and associated risk factors among adults in the Lao People ’s Democratic Republic
ConclusionsOur study provides a nationwide update of the intestinal helminth prevalence among adults in Lao PDR. To the best of our knowledge, this is the first Lao nationwide survey on intestinal helminth infections and risk factors in adults. It provides crucial information for national control programs for intestinal helminth infections in Lao PDR.Graphical abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - June 30, 2023 Category: Infectious Diseases Source Type: research
A live attenuated RH ΔompdcΔuprt mutant of Toxoplasma gondii induces strong protective immunity against toxoplasmosis in mice and cats
ConclusionsThe avirulent RH ΔompdcΔuprt strain can provide strong anti-T. gondii immune responses, and is a promising candidate for developing a safe and effective live attenuated vaccine.Graphical abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - June 15, 2023 Category: Infectious Diseases Source Type: research
Zoonotic sources and the spread of antimicrobial resistance from the perspective of low and middle-income countries
ConclusionsInterventions to contain the spread of AMR should be tailored to the needs of low- and middle-income countries. These comprise capacity building of diagnostic facilities, surveillance, infection prevention and control in small-scale farming.Graphical abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - June 14, 2023 Category: Infectious Diseases Source Type: research
What are the pathways between poverty and malaria in sub-Saharan Africa? A systematic review of mediation studies
ConclusionsFew studies have conducted formal mediation analyses to elucidate pathways between SEP and malaria. Findings indicate that food security and housing could be more feasible (structural) intervention targets. Further research using well-designed longitudinal studies and improved analysis would illuminate the current sparse evidence into the pathways between SEP and malaria and adduce evidence for more potential targets for effective intervention.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - June 8, 2023 Category: Infectious Diseases Source Type: research
Impact of urbanization on morbidity of hepatitis A: a national panel study in China during 2005 –2018
ConclusionsPeople in the western region suffered the heaviest burden of hepatitis A in Chinese mainland. Nationally, there was a sharp decline in the morbidity of hepatitis A. The urbanization process was associated with the reduction of hepatitis A morbidity in China during 2005 –2018.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - May 25, 2023 Category: Infectious Diseases Source Type: research
