Assessing the impact of COVID-19 interventions on influenza-like illness in Beijing and Hong Kong: an observational and modeling study
ConclusionsOur study suggests that COVID-19 NPIs had been reducing outpatient ILI consultations in the presence of other seasonal driving factors in Beijing and the Hong Kong SAR from 2020 to 2021. In cities with varying local circumstances, some NPIs with appropriate stringency may be tailored to reduce the burden of ILI caused by severe influenza strains or other respiratory infections in future.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 16, 2023 Category: Infectious Diseases Source Type: research
Revealing the complexity of vampire bat rabies “spillover transmission”
ConclusionsThe continued study of viral spillover transmission necessitates the elucidation of its complexities to better assess the cross-scale impacts of ecological forces linked to the propensity of spillover success. Improving capacities to reconstruct and predict spillover transmission would prevent public health impacts on those most at risk populations across the globe.Graphical Abstract: (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 13, 2023 Category: Infectious Diseases Source Type: research
Interleukin 6 and interferon gamma haplotypes are related to cytokine serum levels in dogs in an endemic Leishmania infantum region
ConclusionsHaplotypes in theIFNG andIL6 genes have been correlated to serum levels of IFN- γ, IL-2 and IL-18, and a moderate effect has been found onIL8 haplotype correlated to IL-8 and IL-18 serum levels. The results indicate that the resistance toL. infantum infection could be a consequence of certain haplotypes with a high frequency in the Ibizan Hound dog breed, while susceptibility to the disease would be related to other specific haplotypes, with high frequency in Boxer. Future studies are needed to elucidate whether these differences and haplotypes are related to different phenotypes in immune response and expressi...
Source: Infectious Diseases of Poverty - February 10, 2023 Category: Infectious Diseases Source Type: research
Elevated plasma interleukin-8 as a risk factor for mortality in children presenting with cerebral malaria
ConclusionsThe main risk factor of death during CM was thus elevated plasma levels of IL-8 at inclusion. Follow-up of patients until D30 revealed marker profiles of disease aggravation and resolution for markers implicated in neutrophil activation, endothelium activation and damage, inflammatory and oxidative response. These results provide important insight into our understanding of CM pathogenesis and clinical outcome and may have important therapeutic implications.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 9, 2023 Category: Infectious Diseases Source Type: research
Development and validation of a nomogram to predict failure of 14-day negative nucleic acid conversion in adults with non-severe COVID-19 during the Omicron surge: a retrospective multicenter study
ConclusionsOlder age, increasing comorbidities, incomplete vaccinations, and lack of antiviral therapy are risk factors for persistent infection with Omicron variant for > 14 days. A nomogram based on these predictors could be used as a prediction tool to guide treatment and isolation strategies.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 7, 2023 Category: Infectious Diseases Source Type: research
Recognizing and monitoring infectious sources of schistosomiasis by developing deep learning models with high-resolution remote sensing images
ConclusionThe ENVINet5 model is very feasible when the bovine distribution is low in structure with few samples. The Mask R-CNN model has a good framework design and runs highly efficiently. The livestock recognition models developed using deep learning methods with high-resolution remote sensing images accurately recognize the spatial distribution of livestock, which could enable precise control of schistosomiasis.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - February 7, 2023 Category: Infectious Diseases Source Type: research
Associations of socioeconomic status with infectious diseases mediated by lifestyle, environmental pollution and chronic comorbidities: a comprehensive evaluation based on UK Biobank
ConclusionsLow SES is shown to be an important risk factor for infectious disease, part of which may be mediated by poor lifestyle and chronic comorbidities. Efforts to enhance health education and improve the quality of living environment may help reduce burden of infectious disease, especially for people with low SES. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 30, 2023 Category: Infectious Diseases Source Type: research
Life expectancy and healthy life expectancy of patients with advanced schistosomiasis in Hunan Province, China
ConclusionsThe LE of advanced schistosomiasis patients was still much lower compared with general population. Strengthened prevention strategies and targeted treatments are needed to reduce morbidity and mortality due to advanced schistosomiasis, especially for younger population and elderly female patients. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 28, 2023 Category: Infectious Diseases Source Type: research
Use of a “tablet pole” for the administration of ivermectin for strongyloidiasis in a field study in Ecuador
ConclusionsIn our setting, the tablet pole could be a valid alternative. The tool needs further evaluation in different populations.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 28, 2023 Category: Infectious Diseases Source Type: research
Spatio-temporal trends of malaria incidence from 2011 to 2017 and environmental predictors of malaria transmission in Myanmar
ConclusionThe decreasing trends reflect the significant achievement of malaria control efforts in Myanmar. Prioritizing the allocation of resources to high-risk areas identified in this study can achieve effective disease control.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 28, 2023 Category: Infectious Diseases Source Type: research
Optimizing the nucleic acid screening strategy to mitigate regional outbreaks of SARS-CoV-2 Omicron variant in China: a modeling study
ConclusionsIf hotel quarantine, hospital and shelter hospital capacity are seriously insufficient, to stop the spread of the virus as early as possible, high-frequencyFull Screening would be necessary, but intermediate testing frequency may be more cost-effective in non-extreme situations. Screening in batches is recommended if the testing capacity is low.Household-based Sampling Screening is potentially a promising strategy to implement.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - January 16, 2023 Category: Infectious Diseases Source Type: research
Role of social organization engagement in high-risk groups intervention against HIV/AIDS: a case study from 176 cities of China
ConclusionsThe spatial effect of social organizations participating in interventions targeting high-risk populations funded by CAFNGO is statistically significant. Nevertheless, despite the achievements of these social organizations in tracking new cases and encouraging treatment, a series of measures should be taken to further optimize the use of CAFNGO. Working data should be updated from social organizations to CAFNGO more frequently by establishing a data monitoring system to help better track newly diagnosed AIDS cases. Multichannel financing should be expanded as well. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 28, 2022 Category: Infectious Diseases Source Type: research
Profile and determinants of delayed care-seeking and diagnosis among patients with imported malaria: a retrospective study in China, 2014 –2021
ConclusionsBased on this study ’s findings, we strongly advocate for improved access to quality healthcare to reduce the rate of misdiagnosis at the first visit. Infections caused by non-P. falciparum species should be highlighted, and more sensitive and specific point-of-care detection methods for non-P. falciparum species should be developed and implemented. In addition, education programs should be enhanced to reach target populations at risk of malaria infection. All these factors may reduce delayed care-seeking and diagnosis of imported malaria.Graphical Abstract (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 22, 2022 Category: Infectious Diseases Source Type: research
Epidemiological survey and genetic characterization of type 3 vaccine-derived poliovirus isolated from a patient with four doses of inactivated polio vaccine in Henan Province, China
ConclusionsThe existence of this kind of virus in human population is a serious risk and poses a severe challenge in maintaining a polio-free status in China. To the best of our knowledge, this is the first report of VDPV identified in the Henan province of China. Our results highlight the importance of maintaining a high-level vaccination rate and highly sensitive AFP case surveillance system in intercepting VDPV transmission. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 14, 2022 Category: Infectious Diseases Source Type: research
Experiences and perceptions of COVID-19 infection and vaccination among Palestinian refugees in Jerash camp and Jordanian citizens: a comparative cross-sectional study by face-to-face interviews
ConclusionsThis study showed that, compared to citizens, refugees had lower attitudes and practices toward COVID-19 infection and vaccination. They also had and a lower rate of COVID-19 vaccine hesitancy and uptake with limited access to vaccines. Government sectors and non-government organizations should implement policies and regulations to raise the awareness of refugees towards COVID-19 infection, testing, preventive measures, and the safety and efficacy of vaccines. (Source: Infectious Diseases of Poverty)
Source: Infectious Diseases of Poverty - December 13, 2022 Category: Infectious Diseases Source Type: research
