Comparative analysis of pregnancy outcomes in preimplantation genetic testing for aneuploidy and conventional in  vitro fertilization and embryo transfer: a stratified examination on the basis of the quantity of oocytes and blastocysts from a multicenter randomized controlled trial
To investigate variations in pregnancy outcomes between preimplantation genetic testing for aneuploidy (PGT-A) and conventional in  vitro fertilization and embryo transfer (IVF-ET) treatment across distinct groups categorized by oocyte and blastocyst counts. Because the live birth rate (LBR) of assisted reproductive technology treatment is influenced by the number of oocytes and blastocysts retrieved. Our previous study indica ted comparable cumulative LBRs (CLBRs) between conventional IVF-ET and PGT-A. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 14, 2024 Category: Reproduction Medicine Authors: Min Hu, Mingxi Liu, Siqi Tian, Ling Guo, Zhaowen Zang, Zi-Jiang Chen, Yan Li Tags: Assisted reproduction Source Type: research

The impact of microfluidics sperm processing on blastocyst euploidy rates compared with density gradient centrifugation: a sibling oocyte double-blinded prospective randomized clinical trial
To compare the euploidy rates among blastocysts created from sibling oocytes injected with sperm and processed using microfluidics or density gradient centrifugation. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 14, 2024 Category: Reproduction Medicine Authors: Prachi Godiwala, Jane Kwieraga, Emilse Almanza, Evelyn Neuber, Daniel Grow, Claudio Benadiva, Reeva Makhijani, Andrea DiLuigi, David Schmidt, Alison Bartolucci, Lawrence Engmann Tags: Andrology Source Type: research

The impact of microfluidics sperm processing on blastocyst euploidy rates compared to density gradient centrifugation: a sibling oocyte double-blinded prospective randomized clinical trial
Capsule: In this sibling oocyte randomized controlled trial, microfluidics did not improve embryo euploidy rates compared to density gradient centrifugation sperm processing. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 14, 2024 Category: Reproduction Medicine Authors: Prachi Godiwala, Jane Kwieraga, Emilse Almanza, Evelyn Neuber, Daniel Grow, Claudio Benadiva, Reeva Makhijani, Andrea DiLuigi, David Schmidt, Alison Bartolucci, Lawrence Engmann Tags: Andrology Source Type: research

Comparative analysis of pregnancy outcomes in PGT-A and conventional IVF-ET: a stratified examination based on quantity of oocyte and blastocyst from a multicenter randomized controlled trial
Capsule: The conventional IVF-ET group exhibited a lower cumulative clinical pregnancy loss rate than the PGT-A group when the number of retrieved oocytes was (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 14, 2024 Category: Reproduction Medicine Authors: Min Hu, Mingxi Liu, Siqi Tian, Ling Guo, Zhaowen Zang, Zi-Jiang Chen, Yan Li Tags: Assisted reproduction Source Type: research

Assessment of Clinical Pregnancies in Up to Eight Ovarian Stimulation with Intrauterine Insemination Cycles in Those Unable to Proceed With In Vitro Fertilization
To study the primary objective of clinical pregnancy rate per ovarian stimulation intrauterine insemination cycle in patients with repetitive cycles up to a maximum of 8 cycles. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 14, 2024 Category: Reproduction Medicine Authors: M. Blake Evans, Pardis Hosseinzadeh, Kerry Flannagan, Samad Jahandideh, Emilie Burruss, Jennifer D. Peck, Karl R. Hansen, Micah Hill, Kate Devine Tags: Assisted reproduction Source Type: research

Association of serum uric acid with women ’s ovarian reserve: observational study and Mendelian randomization analyses
To investigate the association between serum uric acid and women ’s ovarian reserve. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 12, 2024 Category: Reproduction Medicine Authors: Guiquan Wang, Haiyan Yang, Xintong Jiang, Weian Mao, Ping Li, Xiaojing Lin, Yan Li, Zhenhong Ye, Yurong Zhang, Wei Chen, Shuai Yuan, Yue Zhao, Liangshan Mu Tags: Reproductive endocrinology Source Type: research

The significance of macrosomia after frozen embryo transfer
(Source: Fertility and Sterility)
Source: Fertility and Sterility - February 12, 2024 Category: Reproduction Medicine Authors: Mohamed A. Aboulghar, Mona M. Aboulghar Tags: Reflections Source Type: research

Why laboratory-developed test for endometrial receptivity analysis may have failed to deliver
I read with great interest recent articles by Arian et  al. (1) that raise doubts about the clinical utility of endometrial receptivity analysis (ERA)–guided personalized embryo transfers. The ERA test comprises customized 238-gene microarray panel (replaced now by next-generation sequencing) for precise dating and successful implantation during assi sted reproduction. The use of ERA may fail in the lack of understanding of underlying mechanisms that result in nonreceptive endometrium. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 11, 2024 Category: Reproduction Medicine Authors: Deepa Bhartiya Tags: Letter to the editor Source Type: research

Why lab-developed test for endometrial receptivity analysis (ERA) may have failed to deliver
(Source: Fertility and Sterility)
Source: Fertility and Sterility - February 11, 2024 Category: Reproduction Medicine Authors: Deepa Bhartiya Tags: Letters to the editor Source Type: research

Adenomyosis and infertility: a possible glimmer of light in the dark
(Source: Fertility and Sterility)
Source: Fertility and Sterility - February 11, 2024 Category: Reproduction Medicine Authors: Adolfo Allegra, Angelo Marino Tags: Reflections Source Type: research

To the editor: patient selection for ovarian tissue cryopreservation: should there be a strict age limit?
We thank Brady (1) for their editorial accompanying our manuscript (2). We agree that the age at ovarian tissue cryopreservation (OTC) is a critical factor in ovarian tissue transplantation (OTT) success, similar to how age affects in  vitro fertilization treatment success rates. However, because there are numerous factors that affect OTT success, we do not impose a strict age limit on patient selection. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 9, 2024 Category: Reproduction Medicine Authors: Loris Marin, Fernanda Pacheco, Kutluk H. Oktay Tags: Letter to the editor Source Type: research

Underlying parental infertility and offspring cardiometabolic risk
There remains long-standing interest in the health of children conceived with fertility treatments, particularly conception after the use of assisted reproductive technologies (ARTs). These concerns include the potential for epigenetic changes in early development (1). However, apart from issues of reproducibility, because the ART techniques have changed dramatically over the years, what has also been difficult to disentangle is the confounding due to underlying infertility. In other words, what causes infertility, rather than its treatment, may be what increases long-term health risks to the child. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 9, 2024 Category: Reproduction Medicine Authors: Edwina Yeung Tags: Reflections Source Type: research

Intravaginal exposure to seminal plasma after ovum pick-up does not increase live birth rates after in  vitro fertilization or intracytoplasmic sperm injection treatment: a double-blind, placebo-controlled randomized trial
To detect whether intravaginal exposure to prepared seminal plasma led to an absolute increase in live birth rate (LBR) after in  vitro fertilization (IVF) by 10% compared with placebo. It has been suggested that intravaginal deposition of seminal plasma after ovum pick-up (OPU) for IVF treatment, increases pregnancy and LBRs. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 9, 2024 Category: Reproduction Medicine Authors: Susanne Liffner, Marie Bladh, Heriberto Rodriguez-Martinez, Gunilla Sydsj ö, Stefan Zalavary, Elizabeth Nedstrand Tags: Assisted reproduction Source Type: research

Closing the gap on racial disparities —Increasing race and ethnicity demographics reporting in the Society for Assisted Reproductive Technology Clinic Outcome Reporting System Registry
Even though recording race and ethnicity has been a mandatory reporting field in the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) since the 1990s, up to 48% of cycles reported to SART CORS have been missing this basic demographic metric since 1999. There has been an incremental improvement over the past 20 years, and missing data decreased to 36% for the 2014 –2019 reporting period (1). Although it is unlikely that there would ever be 100% compliance in reporting race and ethnicity in a registry, even this “improved” number is disturbingly high. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 9, 2024 Category: Reproduction Medicine Authors: David B. Seifer, Gloria Richard-Davis, Ruben Alvero Tags: Inklings Source Type: research

Patient Selection for Ovarian Tissue Cryopreservation: Should there be a strict age limit?
(Source: Fertility and Sterility)
Source: Fertility and Sterility - February 9, 2024 Category: Reproduction Medicine Authors: Loris Marin, Fernanda Pacheco, Kutluk Oktay Source Type: research