Crimson clues: advancing endometriosis detection and management with novel blood biomarkers
Endometriosis is an inflammatory condition affecting approximately 10% of the female-born population. Despite its prevalence, the lack of noninvasive biomarkers has contributed to an established global diagnostic delay. The intricate pathophysiology of this enigmatic disease may leave signatures in the blood, which, when detected, can be used as noninvasive biomarkers. This review provides an update on how investigators are utilizing the established disease pathways and innovative methodologies, including genome-wide association studies, next-generation sequencing, and machine learning, to unravel the clues left in the blo...
Source: Fertility and Sterility - February 1, 2024 Category: Reproduction Medicine Authors: Tatjana Gibbons, Nilufer Rahmioglu, Krina T. Zondervan, Christian M. Becker Tags: Views and reviews Source Type: research

Editorial Board
(Source: Fertility and Sterility)
Source: Fertility and Sterility - February 1, 2024 Category: Reproduction Medicine Source Type: research

Table of Contents
(Source: Fertility and Sterility)
Source: Fertility and Sterility - February 1, 2024 Category: Reproduction Medicine Source Type: research

Erratum
for Acker A, Senapati S, Dokras A. Barriers to access: findings from an implementation study of an artificial intelligence –augmented 2-way chatbot for fertility care. Fertil Steril 2023;120:199–201. (Source: Fertility and Sterility)
Source: Fertility and Sterility - February 1, 2024 Category: Reproduction Medicine Tags: Erratum Source Type: research

Some Common, Fatal Flaws in Systematic Reviews of Observational Studies
(Source: Fertility and Sterility)
Source: Fertility and Sterility - February 1, 2024 Category: Reproduction Medicine Authors: Jack Wilkinson, Katie Stocking Tags: Views and reviews Source Type: research

The details matter: personalized prediction of live birth after in  vitro fertilization in women with polycystic ovary syndrome
To derive and internally validate a clinical prediction model for live birth (LB) in women with polycystic ovary syndrome (PCOS) undergoing in  vitro fertilization (IVF). (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 31, 2024 Category: Reproduction Medicine Authors: Laura G. Cooney, Mary D. Sammel, Iris Lee, M. Alexa Clapp, Michelle Goldsammler, Erin Scott, Sarah Bjorkman, Brian T. Fisher, Anuja Dokras Tags: Assisted reproduction Source Type: research

Alterations in nonesterified free fatty acid trafficking rather than hyperandrogenism contribute to metabolic health in obese women with polycystic ovary syndrome
To determine whether alterations in nonesterified fatty acid (NEFA) dynamics or degree of hyperandrogenism (HA) contribute to the difference in insulin sensitivity between women with metabolically healthy obese polycystic ovary syndrome (PCOS) (MHO-PCOS) and women with metabolically unhealthy obese PCOS (MUO-PCOS). (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 31, 2024 Category: Reproduction Medicine Authors: Uche Ezeh, YD Ida Chen, Marita Pall, Richard P. Buyalos, Jessica L. Chan, Margareta D. Pisarska, Ricardo Azziz Tags: Reproductive endocrinology Source Type: research

Reply of the Authors Rossella Cannarella, Rosita Condorelli, Carmelo Gusmano, et  al. Predictive role of 17α-hydroxy-progesterone serum levels before and after follicle-stimulating hormone administration in patients with abnormal sperm parameters
In this prospective study, we analyzed the correlation between serum 17 α-hydroxy-progesterone (17αOH-P) levels and total sperm count in infertile patients diagnosed with idiopathic oligoasthenoteratozoospermia (OAT) and with normal basal follicle-stimulating hormone (FSH) who received 150 IU of FSH three times a week for 3 months. Study results indicated that pre-FSH serum 17αOH-P levels of (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 31, 2024 Category: Reproduction Medicine Authors: Rossella Cannarella, Rosita A. Condorelli, Carmelo Gusmano, Vincenzo Garofalo, Antonio Aversa, Aldo E. Calogero, Sandro La Vignera Tags: Letter to the editor Source Type: research

Re: Re: Rossella Cannarella, Rosita Condorelli, Carmelo Gusmano et al. Predictive role of 17 α-hydroxy-progesterone serum levels before and after FSH administration in patients with abnormal sperm parameters
(Source: Fertility and Sterility)
Source: Fertility and Sterility - January 31, 2024 Category: Reproduction Medicine Authors: Rossella Cannarella, Rosita A. Condorelli, Carmelo Gusmano, Vincenzo Garofalo, Antonio Aversa, Aldo E. Calogero, Sandro La Vignera Tags: Letters to the editor Source Type: research

The details matter: personalized prediction of live birth following in vitro fertilization in women with polycystic ovary syndrome
To derive and internally validate a clinical prediction model for live birth in women with polycystic ovary syndrome (PCOS) undergoing in-vitro fertilization (IVF) (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 31, 2024 Category: Reproduction Medicine Authors: Laura G. Cooney, Mary D. Sammel, Iris Lee, M. Alexa Clapp, Michelle Goldsammler, Erin Scott, Sarah Bjorkman, Brian T. Fisher, Anuja Dokras Tags: Assisted reproduction Source Type: research

Alterations in NEFA trafficking rather than hyperandrogenism contribute to metabolic health in obese women with PCOS
To determine whether alterations in non-esterified free fatty acids (NEFA) dynamics or degree of hyperandrogenism (HA) contribute to the difference in insulin sensitivity between metabolically healthy (MHO-PCOS) and metabolically unhealthy (MUO-PCOS) obese PCOS women. (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 31, 2024 Category: Reproduction Medicine Authors: Uche Ezeh, YD Ida Chen, Marita Pall, Richard P. Buyalos, Jessica L. Chan, Margareta D. Pisarska, Ricardo Azziz Tags: Reproductive endocrinology Source Type: research

A follicular volume of > 0.56 cm3 at trigger is the cutoff to predict oocyte maturity: a starting point for novel volume-based triggering criteria
To determine the minimum follicular volume on the day of trigger that will correspond to a mature oocyte at egg retrieval by individualized follicular puncture and to calculate the mean follicular growth from ovulation induction to egg retrieval using SonoAVCfollicle. (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 28, 2024 Category: Reproduction Medicine Authors: Adela Rodr íguez-Fuentes, Jairo Hernández, Jean Paul Rouleau, Pablo Martín-Vasallo, Angela Palumbo Tags: Assisted reproduction Source Type: research

A follicular volume of > 0.56 cm3 at trigger is the cut-off to predict oocyte maturity: a starting point for novel volume-based triggering criteria.
Capsule: A follicular volume of>0.56 cm3 at trigger is the cut-off point with the optimal balance between sensitivity and specificity for oocyte maturity. (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 28, 2024 Category: Reproduction Medicine Authors: Adela Rodr íguez-Fuentes, Jairo Hernández, Jean Paul Rouleau, Pablo Martín-Vasallo, Angela Palumbo Tags: Assisted reproduction Source Type: research

Tobacco or marijuana use and infertility: a committee opinion
In the United States, approximately 21% of adults report some form of tobacco use, although 18% report marijuana use. Although the negative impact of tobacco use in pregnancy is well documented, the impact of tobacco and marijuana on fertility and reproduction is less clear. This committee opinion reviews the potential deleterious effects of tobacco, nicotine, and marijuana use on conception, ovarian follicular dynamics, sperm parameters, gamete mutations, early pregnancy, and assisted reproductive technology outcomes. (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 27, 2024 Category: Reproduction Medicine Authors: Practice Committee of the American Society for Reproductive Medicine Tags: ASRM pages Source Type: research

Financial ‘‘risk-sharing’’ or refund programs in assisted reproduction: an Ethics Committee opinion
Financial “risk-sharing” fee structures in assisted reproduction programs charge patients a higher initial fee that includes multiple cycles but offers a partial or complete refund if treatment fails. This opinion of the American Society for Reproductive Medicine Ethics Committee analyzes the ethical issu es raised by these fee structures, including patient selection criteria, conflicts of interest, success rate transparency, and patient-informed consent. This document replaces the document of the same name, last published in 2016. (Source: Fertility and Sterility)
Source: Fertility and Sterility - January 25, 2024 Category: Reproduction Medicine Authors: Ethics Committee of the American Society for Reproductive Medicine Tags: ASRM pages Source Type: research