Effect of an Outreach Programme on Vandetanib Safety in Medullary Thyroid Cancer
Conclusions: Additional outreach to patients treated with vandetanib had no impact on the rate or severity of AEs compared to the standard AE monitoring schedule. AEs were consistent with the known safety profile of vandetanib.Eur Thyroid J 2016;5:187-194 (Source: European Thyroid Journal)
Source: European Thyroid Journal - September 9, 2016 Category: Endocrinology Source Type: research
An Unusual Case of Malignant Struma Ovarii Causing Thyrotoxicosis
Conclusion: There has been controversy about the management of malignant SO, which is a rare entity. Malignant SO causing thyrotoxicosis is even more uncommon. As clinical signs are nonspecific, other causes of thyrotoxicosis must be considered for a differential diagnosis. Our case is one of the very few cases ever reported.Eur Thyroid J 2016;5:207-211 (Source: European Thyroid Journal)
Source: European Thyroid Journal - September 7, 2016 Category: Endocrinology Source Type: research
Correction of Hypothyroidism Leads to Change in Lean Body Mass without Altering Insulin Resistance
This study assessed changes in body composition and insulin resistance after thyroxine (T4) replacement in overt hypothyroidism.Methods: In this prospective longitudinal study carried out in a tertiary care center, adult nondiabetic patients with overt hypothyroidism were rendered euthyroid on T4. Anthropometry including skinfold thickness (SFT) at the triceps and subscapularis was recorded. Patients underwent testing for fasting plasma glucose, creatinine, serum insulin, T4, thyrotropin (TSH) and body composition analysis by dual-energy X-ray absorptiometry (DEXA) both before and at 2 months after restoration to the euthy...
Source: European Thyroid Journal - September 7, 2016 Category: Endocrinology Source Type: research
Painful Radiation Thyroiditis after 131I Therapy for Graves' Hyperthyroidism: Clinical Features and Ultrasonographic Findings in Five Cases
Conclusion: Painful radiation thyroiditis should be reacknowledged as one of the complications of131I therapy for Graves' hyperthyroidism. Ultrasonography demonstrated the characteristic changes caused by131I-induced radiation thyroiditis.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - September 6, 2016 Category: Endocrinology Source Type: research
Painful Radiation Thyroiditis after < sup > 131 < /sup > I Therapy for Graves' Hyperthyroidism: Clinical Features and Ultrasonographic Findings in Five Cases
Conclusion: Painful radiation thyroiditis should be reacknowledged as one of the complications of131I therapy for Graves' hyperthyroidism. Ultrasonography demonstrated the characteristic changes caused by131I-induced radiation thyroiditis.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - September 5, 2016 Category: Endocrinology Source Type: research
Periodic Granulocyte Count Measuring Is Useful for Detecting Asymptomatic Agranulocytosis in Antithyroid Drug-Treated Patients with Graves' Disease
Objective: Finding agranulocytosis (AG) at an early stage is important to improve outcome, but periodic granulocyte count monitoring is not generally recommended for patients with Graves' disease, because AG develops suddenly.Method: At the Kuma Hospital, Graves' patients under antithyroid drug (ATD) treatment in an outpatient clinic have a granulocyte count examination during each visit, and if it is (Source: European Thyroid Journal)
Source: European Thyroid Journal - September 5, 2016 Category: Endocrinology Source Type: research
In Memoriam Professor Peter M. Laurberg
Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - September 1, 2016 Category: Endocrinology Source Type: research
Thyroid Function and High-Sensitivity C-Reactive Protein in Cross-Sectional Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): Effect of Adiposity and Insulin Resistance
Conclusions: TSH is not associated with hs-CRP. Obesity and insulin resistance are very important confounders in the study of the association between SCH and hs-CRP.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - September 1, 2016 Category: Endocrinology Source Type: research
BRAFV600E Mutation: Has It a Role in Cervical Lymph Node Metastasis of Papillary Thyroid Cancer
Conclusions: In our study, the BRAFV600E mutation did not show a one-to-one correspondence. This indicates that the presence of BRAFV600E in the primary tumor is not clonal and addresses the role of intratumor heterogeneity in PTC tumorigenesis. This supports the theses that mutations occur in the later stages of tumorigenesis, might be subclonal, and develop de novo, or that some other factors may be involved in the development of metastasis.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - August 22, 2016 Category: Endocrinology Source Type: research
BRAF < sup > V600E < /sup > Mutation: Has It a Role in Cervical Lymph Node Metastasis of Papillary Thyroid Cancer?
Conclusions: In our study, the BRAFV600E mutation did not show a one-to-one correspondence. This indicates that the presence of BRAFV600E in the primary tumor is not clonal and addresses the role of intratumor heterogeneity in PTC tumorigenesis. This supports the theses that mutations occur in the later stages of tumorigenesis, might be subclonal, and develop de novo, or that some other factors may be involved in the development of metastasis.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - August 19, 2016 Category: Endocrinology Source Type: research
Relational Stability of Thyroid Hormones in Euthyroid Subjects and Patients with Autoimmune Thyroid Disease
Background/Aim: Operating far from its equilibrium resting point, the thyroid gland requires stimulation via feedback-controlled pituitary thyrotropin (TSH) secretion to maintain adequate hormone supply. We explored and defined variations in the expression of control mechanisms and physiological responses across the euthyroid reference range.Methods: We analyzed the relational equilibria between thyroid parameters defining thyroid production and thyroid conversion in a group of 271 thyroid-healthy subjects and 86 untreated patients with thyroid autoimmune disease.Results: In the euthyroid controls, the FT3-FT4 (free triiod...
Source: European Thyroid Journal - August 18, 2016 Category: Endocrinology Source Type: research
General Information
Eur Thyroid J 2016;5(suppl 1):189-194 (Source: European Thyroid Journal)
Source: European Thyroid Journal - August 16, 2016 Category: Endocrinology Source Type: research
Industry-Sponsored Satellite Symposia
Eur Thyroid J 2016;5(suppl 1):177-188 (Source: European Thyroid Journal)
Source: European Thyroid Journal - August 16, 2016 Category: Endocrinology Source Type: research
Abstracts
Eur Thyroid J 2016;5(suppl 1):57-176 (Source: European Thyroid Journal)
Source: European Thyroid Journal - August 16, 2016 Category: Endocrinology Source Type: research
Title Page / Table of Contents / Scientific and Organizing Committees
Eur Thyroid J 2016;5(suppl 1):I-VIII (Source: European Thyroid Journal)
Source: European Thyroid Journal - August 16, 2016 Category: Endocrinology Source Type: research
