Aspirin Increases the Risk of Nondiagnostic Yield of Fine-Needle Aspiration and Biopsy of Thyroid Nodules
Conclusions: This is the first study to demonstrate a 3-fold independently greater risk of a nondiagnostic FNAB cytology in patients taking aspirin. Our results highlight the importance of evaluating the need for continuation of aspirin in patients undergoing thyroid FNAB as this may impact the diagnostic yield of the procedure.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - May 16, 2018 Category: Endocrinology Source Type: research
Thyroid Swelling: A Common Phenomenon in Art?
Representations of thyroid swelling, intended as an enlarged anterior neck region, in the artworks of various periods are sporadically reported in the scientific literature, and different intents may be hypothesized. A comprehensive review of the international literature was performed on PubMed, Embase, and ResearchGate with the aim to analyze the modalities of representation of thyroid swelling through the ages by different artistic movements. Thyroid swelling is frequently represented in the artworks of many stylistic periods and seems to be a known condition even by the earliest cultures. Thyroid swelling may be conside...
Source: European Thyroid Journal - May 3, 2018 Category: Endocrinology Source Type: research
Variables Contributing to Thyroid (Dys)Function in Pregnant Women: More than Thyroid Antibodies?
Variability in thyroid function in pregnant women is the result of 2 main determinants, each accounting for approximately half of it. The first is the genetically determined part of which the knowledge increases fast, but most remains to be discovered. The second determinant is caused by an ensemble of variables of which thyroid autoimmunity is the best known, but also by others such as parity, smoking, age, and BMI. More recently, new candidate variables have been proposed, such as iron, endocrine disruptors, and the ethnicity of the pregnant women. In the future, the diagnosis and treatment of thyroid (dys)function may b...
Source: European Thyroid Journal - April 27, 2018 Category: Endocrinology Source Type: research
Bethesda Classification and Cytohistological Correlation of Thyroid Nodules in a Brazilian Thyroid Disease Center
Conclusion: The Bethesda System can be applied to the Brazilian population, since the frequency and malignancy rates of each category were similar to those described by its classification. It is noteworthy that a higher risk of malignancy was observed in the ND cytological category.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - April 27, 2018 Category: Endocrinology Source Type: research
Sorafenib-Induced Acute Pancreatitis in a Patient with Differentiated Thyroid Cancer
Conclusions: Sorafenib-acute pancreatitis may develop in patients with RAI-refractory thyroid cancer. This adverse event seems to be inde pendent of the treatment duration and administered dose. Resuming the medication with an adjusted dose after pancreatitis resolution may be safe.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - April 25, 2018 Category: Endocrinology Source Type: research
Noninflammatory Diffuse Follicular Hypertrophy/Hyperplasia of Graves Disease: Morphometric Evaluation in an Experimental Mouse Model
Conclusion: GD thyroid glands are enlarged and characterized by a noninflammatory diffuse follicular cell hyperplasia/hypertrophy and a significant increase in the follicles with an increased follicle/stroma ratio. Overall, this mouse model is a faithful model of an early hyperthyroid status of GD (diffuse glandular involvement and follicular expansion).Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - April 13, 2018 Category: Endocrinology Source Type: research
Lenvatinib for Anaplastic Thyroid Cancer and Lenvatinib-Induced Thyroid Dysfunction
Conclusions: Lenvatinib is an effective treatment and may improve the prognosis of unresectable ATC. Four of the 5 patients had hypothyroidism, which may have been associated with treatment-induced injury of the thyroid gland. There were many treatment-related adverse effects, most of which were manageable by dose modification and medical therapy.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - February 21, 2018 Category: Endocrinology Source Type: research
Successful Treatment of Differentiated Thyroid Carcinoma with Transaxillary Robotic Surgery and Radioiodine: The First European Experience
Conclusion: In this study, TARS followed by RAI therapy seems to be curative, even for patients with lymph node metastases, after good preoperative staging. More studies are required to confirm the findings.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - February 21, 2018 Category: Endocrinology Source Type: research
Prevalence of Radiological Signs of Dysthyroid Optic Neuropathy in Magnetic Resonance Imaging in Patients with Active, Moderate-to-Severe, and Very Severe Graves Orbitopathy
Conclusions: MRI is a useful tool in evaluating very severe GO. However, features typical for DON are also found in up to 35% of eyes in patients with active, moderate-to-severe GO. Therefore, ophthalmological evaluation seems to be most important in the recognition of very severe GO.Eur Thyroid J 2018;7:88 –94 (Source: European Thyroid Journal)
Source: European Thyroid Journal - February 15, 2018 Category: Endocrinology Source Type: research
2018 European Thyroid Association (ETA) Guidelines for the Management of Amiodarone-Associated Thyroid Dysfunction
Treatment with amiodarone is associated with changes in thyroid function tests, but also with thyroid dysfunction (amiodarone-induced hypothyroidism, AIH, and amiodarone-induced thyrotoxicosis, AIT). Both AIH and AIT may develop in apparently normal thyroid glands or in the presence of underlying thyroid abnormalities. AIH does not require amiodarone withdrawal, and is treated with levothyroxine replacement if overt, whereas subclinical forms may be followed without treatment. Two main types of AIT are recognized: type 1 AIT (AIT 1), a form of iodine-induced hyperthyroidism occurring in nodular goitres or latent Graves dis...
Source: European Thyroid Journal - February 14, 2018 Category: Endocrinology Source Type: research
Nodules ≤1 cm with Highly Suspicious Ultrasound Features and Papillary Microcarcinoma of the Thyroid: Is Fine-Needle Aspiration Cytology Necessary before Deciding on Active Surveillance?
Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 23, 2018 Category: Endocrinology Source Type: research
Liposarcoma of the Thyroid: A Case Report with a Review of the Literature
Conclusions: Our review provides clinical and histopathological features of a primary liposarcoma of the thyroid to enable the identifi cation of this rare tumor entity and assist in the decision-making process regarding therapeutic options and tumor follow-up.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 19, 2018 Category: Endocrinology Source Type: research
In Memoriam: Gabriella Morreale de Escobar
Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 16, 2018 Category: Endocrinology Source Type: research
Thyroid Cancer Induction: Nitrates as Independent Risk Factors or Risk Modulators after Radiation Exposure, with a Focus on the Chernobyl Accident
In conclusion, excess nitrate intake seems to be an independent risk factor for DTC. Additionally, we hypothesize from our data that high nitrate levels modulate the carcinogenic effect of radiation on the thyroid. Cohort studies, case-control studies, or both, are needed to quantify the effects of nitrates on DTC risk in the presence or absence of radiation exposure, e.g., that associated with diagnostic or therapeutic health care interventions.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 11, 2018 Category: Endocrinology Source Type: research
Effects of Chronic Lymphocytic Thyroiditis on the Clinicopathological Features of Papillary Thyroid Cancer
Conclusions: CLT in patients with PTC was associated with lower-stage disease and less disease persistence in patients #x3e;45 years of age. In patients #x3c;45 years, the presence of CLT appeared to be associated with unfavorable pathological features.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 10, 2018 Category: Endocrinology Source Type: research
