Reference Values for TSH and Free Thyroid Hormones in Healthy Pregnant Women in Poland: A Prospective, Multicenter Study
Conclusions: Using appropriate trimester-specific reference intervals may improve care of pregnant women by preventing misdiagnosis and inadequate treatment.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - February 2, 2017 Category: Endocrinology Source Type: research

A Novel Mutation in the < b > < i > TBG < /i > < /b > Gene Producing Partial Thyroxine-Binding Globulin Deficiency (Glencoe) Identified in 2 Families
Conclusions: We report a novel mutation in theTBG gene in 2 unrelated families that produces a molecule with reduced affinity for T4 resulting in low serum T4. However, the physical properties of the mutant molecule remained unaltered as determined by isoelectric focusing.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - February 1, 2017 Category: Endocrinology Source Type: research

A Cervical Schwannoma Masquerading as a Thyroid Nodule
Conclusion: Pharyngeal wall schwannomas are important to consider in the differential diagnosis of thyroid nodules when fine needle aspiration cytology indicates cells of neural origin. Imaging by MRI can assist in identifying lesions of neural origin masquerading as thyroid nodules.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 20, 2017 Category: Endocrinology Source Type: research

Nonalcoholic Fatty Liver Disease Is Not Associated with Thyroid Hormone Levels and Hypothyroidism: A Systematic Review and Meta-Analysis
Conclusions: Our meta-analysis demonstrates no significant association between NAFLD and subclinical, overt, or overall hypothyroidism, and we also found no significant difference in thyroid hormone levels between participants with and without NAFLD.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 20, 2017 Category: Endocrinology Source Type: research

Neither Baseline nor Changes in Serum Triiodothyronine during Levothyroxine/Liothyronine Combination Therapy Predict a Positive Response to This Treatment Modality in Hypothyroid Patients with Persistent Symptoms
Conclusion: Our data indicate that serum T3 measurements are not suitable to predict which patient will benefit from L-T4/L-T3 combination therapy, and treatment response cannot be followed by repeated T3 measurements either.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 18, 2017 Category: Endocrinology Source Type: research

Should Age at Diagnosis Be Included as an Additional Variable in the Risk of Recurrence Classification System in Patients with Differentiated Thyroid Cancer?
Conclusions: When patients are correctly risk stratified, it seems that age at diagnosis is not involved in the frequency of having a SIR at the initial evaluation or at the final follow-up, so it should not be included as an additional variable to be considered in the RR classifications.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 6, 2017 Category: Endocrinology Source Type: research

Survey of Clinical Practice Patterns in the Management of 992 Hyperthyroid Patients in France
Conclusions: Large discrepancies remain between clinical practice and international guidelines. These results should boost efforts to improve adherence to these guidelines.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - January 4, 2017 Category: Endocrinology Source Type: research

A 2016 Italian Survey about Guidelines and Clinical Management of Thyroid Nodules
Conclusions: Efforts are needed to make the guidelines more user-friendly and to encourage the use of codified risk categories in thyroid US reports. FNA indications remain a matter of debate as FNA is obtained in clinical practice more often than is recommended. Current US follow-up modalities for a benign nodule are correct, but probably could be performed less frequently without any harm. Molecular testing, if accessible, would be helpful in guiding clinicians' strategies in cases of AUS/FLUS-TIR3A cytologic results. Nonsurgical procedures are favorably embraced.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - December 28, 2016 Category: Endocrinology Source Type: research

Variability among TSH Measurements Can Be Reduced by Combining a Glycoengineered Calibrator to Epitope-Defined Immunoassays
Conclusions: A glycoengineered TSH with serum-type glycosylation proved to be a new calibrator efficient in harmonizing TSH values.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - December 21, 2016 Category: Endocrinology Source Type: research

Subject Index Vol. 5, 2016
Eur Thyroid J 2016;5:283-284 (Source: European Thyroid Journal)
Source: European Thyroid Journal - December 15, 2016 Category: Endocrinology Source Type: research

Author Index Vol. 5, 2016
Eur Thyroid J 2016;5:281-282 (Source: European Thyroid Journal)
Source: European Thyroid Journal - December 15, 2016 Category: Endocrinology Source Type: research

Contents Vol. 5, 2016
Eur Thyroid J 2016;5:I-VI (Source: European Thyroid Journal)
Source: European Thyroid Journal - December 15, 2016 Category: Endocrinology Source Type: research

“Nodule in Nodule” on Thyroid Ultrasonography: Possibility of Follicular Carcinoma Transformed from Benign Thyroid Tumor
Conclusion: A small number of patients with follicular carcinomas or follicular neoplasms may present with a “nodule in nodule” appearance on ultrasonography. It was suggested a long time ago that follicular carcinomas may develop from benign thyroid tumors. The fact that follicular carcinomas appear within benign tumors may be evidence of thyroid tumorigenesis.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - December 12, 2016 Category: Endocrinology Source Type: research

When Is Thyroidectomy the Right Choice Comparison between Fine-Needle Aspiration and Final Histology in a Single Institution Experience
Conclusions: Our data suggest that follow-up alone is not sufficient in TIR-3A patients given the high prevalence of malignancy within that diagnostic category (20.45%) and the low sensitivity (75.68%) and specificity (59.32%) in the distinction between TIR-3A and TIR-3B. Regarding patients with a multinodular goiter and TIR-2 at FNA, the surgical approach should not be excluded.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - December 8, 2016 Category: Endocrinology Source Type: research

When Is Thyroidectomy the Right Choice? Comparison between Fine-Needle Aspiration and Final Histology in a Single Institution Experience
Conclusions: Our data suggest that follow-up alone is not sufficient in TIR-3A patients given the high prevalence of malignancy within that diagnostic category (20.45%) and the low sensitivity (75.68%) and specificity (59.32%) in the distinction between TIR-3A and TIR-3B. Regarding patients with a multinodular goiter and TIR-2 at FNA, the surgical approach should not be excluded.Eur Thyroid J (Source: European Thyroid Journal)
Source: European Thyroid Journal - December 7, 2016 Category: Endocrinology Source Type: research