Improving Outcomes with Chemoradiotherapy in the Mucosal Squamous Cell Carcinomas – Immune Checkpoint Inhibition and Broken Promises
(Source: Clinical Oncology)
Source: Clinical Oncology - September 15, 2023 Category: Radiology Authors: R. Samuel, A. Samson, D.C. Gilbert Tags: Editorial Source Type: research
Stereotactic Body Radiotherapy for Spine Oligometastases: A Multicentre Retrospective Study From the Italian Association of Radiotherapy and Clinical Oncology (AIRO)
To evaluate the efficacy of stereotactic body radiotherapy (SBRT) for spine oligometastases. (Source: Clinical Oncology)
Source: Clinical Oncology - September 7, 2023 Category: Radiology Authors: F. Cuccia, E. Pastorello, C. Franzese, L. Belgioia, M. Bignardi, M. Federico, V. Figlia, N. Giaj Levra, S. Badellino, P. Borghetti, G. Marvaso, G. Montesi, A. Pontoriero, I. Fazio, G. Ferrera, F. Alongi, M. Scorsetti Tags: Original Article Source Type: research
Stereotactic body radiotherapy for spine oligometastases: a multicenter retrospective study from Italian Association of Radiotherapy and Clinical Oncology (AIRO)
To evaluate the efficacy of stereotactic body radiotherapy (SBRT) for spine oligometastases. (Source: Clinical Oncology)
Source: Clinical Oncology - September 7, 2023 Category: Radiology Authors: Francesco Cuccia, Edoardo Pastorello, Ciro Franzese, Liliana Belgioia, Mario Bignardi, Manuela Federico, Vanessa Figlia, Niccol ò Giaj Levra, Serena Badellino, Paolo Borghetti, Giulia Marvaso, Giampaolo Montesi, Antonio Pontoriero, Ivan Fazio, Giuseppe F Tags: Original Article Source Type: research
OncoFlash – Research Updates in a Flash! (October edition)
Long-Term Follow-up of a Randomized Control Trial on Accelerated Radiation Therapy Versus Standard Fractionated Radiation Therapy for Early Glottic Cancer (JCOG0701A3). Kodaira, T et al. Int J Radiat Oncol Biol Phys, 2023 [1]. (Source: Clinical Oncology)
Source: Clinical Oncology - September 6, 2023 Category: Radiology Authors: C. Crockett, R. Sim ões Source Type: research
RCR Meetings
(Source: Clinical Oncology)
Source: Clinical Oncology - September 6, 2023 Category: Radiology Source Type: research
The National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group Workshop: Translating Novel Discoveries to and from the Clinic
The National Cancer Research Institute (NCRI) Clinical and Translational Radiotherapy Research Working Group (CTRad) has recognised improving translational research in radiation oncology as a strategic priority area and has established a new working group, Working Group 1, to address the gaps in this field. Here we report on a recent workshop, led by the CTRad Working Group 1, focusing on translating novel discoveries to and from the clinic. It aimed to engage the UK-wide radiotherapy research community to discuss the current challenges and opportunities in this space. (Source: Clinical Oncology)
Source: Clinical Oncology - September 6, 2023 Category: Radiology Authors: C. Chan Wah Hak, J.A. Dean, M.A. Hill, N. Somaiah, The National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group 1 Tags: Editorial Source Type: research
NCRI CTRad workshop: Translating novel discoveries to and from the clinic
(Source: Clinical Oncology)
Source: Clinical Oncology - September 6, 2023 Category: Radiology Authors: Charleen C.W. Hak, Jamie A. Dean, Mark A. Hill, Navita Somaiah, NCRI Clinical and Translational Radiotherapy Research Working Group 1, members Tags: Editorial Source Type: research
Definitive Stereotactic Body Radiation Therapy in Early-Stage Solitary Hepatocellular Carcinoma: An Australian Multi-Institutional Review of Outcomes
We report the outcomes of patients with solitary early-stage HCC treated with SBRT as first-line curative-intent therapy. (Source: Clinical Oncology)
Source: Clinical Oncology - September 4, 2023 Category: Radiology Authors: H.Y.-h. Liu, Y.-y.D. Lee, S. Sridharan, W. Wang, R. Khor, J. Chu, A. Oar, E.S. Choong, H. Le, M. Shanker, A. Wigg, K. Stuart, D. Pryor Tags: Original Article Source Type: research
Definitive SBRT in early-stage solitary HCC: an Australian multi-institutional review of outcomes
We report outcomes of patients with solitary early-stage HCC treated with SBRT as first-line curative intent therapy. (Source: Clinical Oncology)
Source: Clinical Oncology - September 4, 2023 Category: Radiology Authors: Howard Yu-hao Liu, Yoo-young Dominique Lee, Swetha Sridharan, Wei Wang, Richard Khor, Julie Chu, Andrew Oar, Ee Siang Choong, Hien Le, Mihir Shanker, Alan Wigg, Katherine Stuart, David Pryor Tags: Original Article Source Type: research
Radiosensitising Effects of Metformin Added to Concomitant Chemoradiotherapy with Cisplatin in Cervical Cancer
The role of metformin on the radiosensitising effect of cisplatin is not clear. Here we investigated the radiosensitising effect of metformin alone and combined with cisplatin in HeLa cells, as well as the implications of the adenosine monophosphate-activated protein kinase (AMPK) pathway on the radiosensitising effect. (Source: Clinical Oncology)
Source: Clinical Oncology - September 1, 2023 Category: Radiology Authors: C.S. Beduk Esen, M.E. Gedik, H. Canpinar, F.Y. Yedekci, F. Yildiz, G. Gunaydin, M. Gultekin Tags: Original Article Source Type: research
Machine learning study of SNPs in noncoding regions to predict non-small cell lung cancer susceptibility
Non-small cell lung cancer (NSCLC) is the most common pathological subtype of lung cancer. Both environmental and genetic factors have been reported to impact the lung cancer susceptibility. We conducted a genome-wide association study (GWAS) of 287 NSCLC patients and 467 healthy controls in a Chinese population using the Illumina Genome-Wide Asian Screening Array Chip on 712,095 SNPs (single nucleotide polymorphisms). Using logistic regression modeling, GWAS identified 17 new noncoding region SNP loci associated with the NSCLC risk, and the top three (rs80040741, rs9568547, rs6010259) were under a stringent p-value ( (Sou...
Source: Clinical Oncology - September 1, 2023 Category: Radiology Authors: Yan Huang, Ting Bao, Tingting Zhang, Guiyi Ji, Youjuan Wang, Zhihao Ling, Weimin Li Tags: Original Article Source Type: research
Radiosensitizing Effects of Metformin Added to Concomitant Chemoradiotherapy with Cisplatin in Cervical Cancer
The role of metformin on the radiosensitizing effect of cisplatin is not clear. Here we investigated the radiosensitizing effect of metformin alone and combined with cisplatin in HeLa cells as well as the implications of adenosine monophosphate-activated protein kinase (AMPK) pathway on the radiosensitizing effect. (Source: Clinical Oncology)
Source: Clinical Oncology - September 1, 2023 Category: Radiology Authors: Caglayan Selenge Beduk Esen, Mustafa Emre Gedik, Hande Canpinar, Fazli Yagiz Yedekci, Ferah Yildiz, Gurcan Gunaydin, Melis Gultekin Tags: Original Article Source Type: research
Surveillance and Deregulated Pathways in Oral Merkel Cell Carcinoma
Sir — Merkel cell carcinoma (MCC) is an infrequent and incredibly destructive cutaneous neuroendocrine tumour. The tumour cells include neurosecretory granules, which are similar to those found in healthy Merkel cells [1]. MCC commonly manifests as an erythematous lesion in the dermal region of skin t hat is expanding quickly [2]. Rapid systemic tumour progression is also present, together with rapid local growth. The liver, bone and brain are distant organs where MCC frequently metastasises [3]. (Source: Clinical Oncology)
Source: Clinical Oncology - August 31, 2023 Category: Radiology Authors: D.J. Mukesh Kumar, P. Ramasamy, S. Suresh Kumar, P. Sivagurunathan Tags: Letter Source Type: research
Surveillance and deregulated pathways in oral Merkel Cell Carcinoma (MCC)
(Source: Clinical Oncology)
Source: Clinical Oncology - August 31, 2023 Category: Radiology Authors: D.J. Mukesh Kumar, P. Ramasamy, S. Suresh Kumar, S. Paramasivam Tags: Letter Source Type: research
Geographical Variation in Underlying Social Deprivation, Cardiovascular and Other Comorbidities in Patients with Potentially Curable Cancers in England: Results from a National Registry Dataset Analysis
To describe the prevalence of cardiovascular disease (CVD), multiple comorbidities and social deprivation in patients with a potentially curable cancer in 20 English Cancer Alliances. (Source: Clinical Oncology)
Source: Clinical Oncology - August 31, 2023 Category: Radiology Authors: J.V. Waterhouse, C.A. Welch, N.M.L. Battisti, M.J. Sweeting, L. Paley, P.C. Lambert, J. Deanfield, M. de Belder, M.D. Peake, D. Adlam, A. Ring Tags: Original Article Source Type: research
