The National Radiotherapy Trials Quality Assurance Group – Driving Up Quality in Clinical Research and Clinical Care
(Source: Clinical Oncology)
Source: Clinical Oncology - February 1, 2024 Category: Radiology Authors: E. Miles, J. Wadsley, P. Diez, R. Patel, S. Gwynne Tags: Editorial Source Type: research
Quality of Radiotherapy Workforce Training within the USA
The training, competency requirements and scope of practice of professionals within a radiation oncology department vary across countries. The purpose of this review is to shed light on the current status of radiotherapy training in the USA by discussing current benchmarks for medical residency, physics residency, radiation therapy and dosimetry training programmes. Although there are notable strengths, the US radiotherapy workforce training system also faces several challenges when it comes to standardising education to develop a competent workforce that meets societal needs. (Source: Clinical Oncology)
Source: Clinical Oncology - February 1, 2024 Category: Radiology Authors: R. Mulherkar, D.C. Ling, R. Tendulkar, M.R. Kamrava, S. Beriwal Source Type: research
Clinicopathological Profile and Survival Outcomes in Patients with Localised Extremity Synovial Sarcomas
Synovial sarcoma is a rare but aggressive variant of soft-tissue sarcoma. Literature is sparse and reported mostly from the West. We analysed the clinical profiles and prognostic factors of extremity synovial sarcoma patients in order to study their clinical journey. [AQ1] (Source: Clinical Oncology)
Source: Clinical Oncology - January 31, 2024 Category: Radiology Authors: J. Sharma, S.V.S. Deo, S. Kumar, A.W. Barwad, S. Rastogi, D.N. Sharma, G. Singh, S. Bhoriwal, A. Mishra, R. K, J. Saikia, A. Mandal, B. Bansal, M. Gaur Tags: Original Article Source Type: research
Efficacy and Safety of Preoperative Transcatheter Rectal Arterial Chemoembolisation in Patients with Locally Advanced Rectal Cancer: Results from a Prospective, Phase II PCAR Trial
The PCAR study aimed to assess the efficacy and safety of preoperative transcatheter rectal arterial chemoembolisation (TRACE) in patients with locally advanced rectal cancer (LARC). (Source: Clinical Oncology)
Source: Clinical Oncology - January 28, 2024 Category: Radiology Authors: Weina Yang, Chengyuan Qian, Jiamin Luo, Chuan Chen, Yan Feng, Nan Dai, Xuemei Li, Xiao He, Yuxin Yang, Mengxia Li, Chunxue Li, Dong Wang Tags: Original Article Source Type: research
Big Data and Colorectal Cancer: The Revolution will be Personalised
(Source: Clinical Oncology)
Source: Clinical Oncology - January 22, 2024 Category: Radiology Authors: Christopher J.M. Williams, Jenny F. Seligmann Tags: Editorial Source Type: research
Trends and Variation in the Use of Radiotherapy in Non-metastatic Rectal Cancer: a 14-year Nationwide Overview from the Netherlands
This study describes nationwide primary radiotherapy utilisation trends for non-metastasised rectal cancer in the Netherlands between 2008 and 2021. In 2014, both colorectal cancer screening and a new guideline specifying prognostic risk groups for neoadjuvant treatment were implemented. (Source: Clinical Oncology)
Source: Clinical Oncology - January 19, 2024 Category: Radiology Authors: A.-S.E. Verrijssen, J. Evers, M. van der Sangen, S. Siesling, M.J. Aarts, H. Struikmans, M.C.W.M. Bloemers, J. Burger, V. Lemmens, P. Braam, M. Elferink, M. Berbee Tags: Original Article Source Type: research
An Ontario Health (Cancer Care Ontario) Clinical Practice Guideline: Surveillance Strategies in Patients with Stage I, II, III or Resectable IV Melanoma who were Treated with Curative Intent
To make recommendations on managing the surveillance of patients with stage I, II, III or resectable IV melanoma who are clinically free of disease following treatment with curative intent. (Source: Clinical Oncology)
Source: Clinical Oncology - January 19, 2024 Category: Radiology Authors: S. Rajagopal, X. Yao, W. Abadir, T.D. Baetz, A. Easson, G. Knight, E. McWhirter, C. Nessim, C.F. Rosen, A. Sun, F.C. Wright, T.M. Petrella Tags: Guidelines Source Type: research
Evaluation of Delivered Doses in Proton Beam Therapy for Prostate Cancer Using Positron Emission Tomography/Computed Tomography Imaging
Proton beams deposit energy along their paths and stop abruptly without penetrating the opposite side, making it difficult to detect their actual paths. However, confirming the path may lead to evaluating the actual doses to organs at risk in proton therapy for prostate cancer. As proton beams produce positron emitters through nuclear fragmentation reactions, theoretically, proton beam paths can be measured by positron emission tomography/computed tomography (PET/CT). Therefore, this study investigated whether conducting PET/CT examinations immediately after proton beam therapy helps to assess the doses delivered to the re...
Source: Clinical Oncology - January 18, 2024 Category: Radiology Authors: S. Shiraishi, M. Yamanaka, T. Murai, K. Tokuuye Tags: Original Article Source Type: research
Predictors of Quality of Life Decline in Patients with Oligometastases treated with Stereotactic Ablative Radiotherapy: Analysis of the Population-Based SABR-5 Phase II Trial
This study aimed to identify risk factors for QoL decline. (Source: Clinical Oncology)
Source: Clinical Oncology - January 17, 2024 Category: Radiology Authors: E.M. Cruz-Lim, B. Mou, W. Jiang, M. Liu, A. Bergman, D. Schellenberg, A. Alexander, T. Berrang, A. Bang, N. Chng, Q. Matthews, H. Carolan, F. Hsu, S. Miller, S. Atrchian, E. Chan, C. Ho, I. Mohamed, A. Lin, V. Huang, A. Mestrovic, D. Hyde, C. Lund, H. Pai Tags: Original Article Source Type: research
Improved Dosimetry with Daily Online Adaptive Radiotherapy for Cervical Cancer: Waltzing the Pear
Standard of care radiotherapy for locally advanced cervical cancer includes large margins to ensure the uterocervix remains within the treatment fields over the course of treatment. Daily online cone-beam adaptive radiotherapy corrects for interfractional changes by adjusting the plan to match the target position during each treatment session, thus allowing for significantly reduced clinical target volume (CTV) to planning target volume (PTV) margins. We hypothesise that reduced margins from daily online adaptive radiotherapy will reduce organ at risk dose without compromising target coverage. (Source: Clinical Oncology)
Source: Clinical Oncology - January 16, 2024 Category: Radiology Authors: A. Yen, Xinran Zhong, Mu-Han Lin, C. Nwachukwu, K. Albuquerque, B. Hrycushko Tags: Original Article Source Type: research
Decline in Cancer Diagnoses during the ‘Zero COVID’ Policy in Hong Kong: Indirect Spillover Impact of the COVID-19 Pandemic
Despite a largely successful ‘zero COVID’ policy in 2020, the COVID-19 pandemic disrupted routine cancer services in the city of Hong Kong. The aims of this study were to examine the trends in cancer incidence before and during the COVID-19 pandemic and estimate missed cancer diagnoses. (Source: Clinical Oncology)
Source: Clinical Oncology - January 15, 2024 Category: Radiology Authors: H.M. Youn, Y. Zhang, A. Liu, C.S. Ng, J. Liang, G.K.K. Lau, S.F. Lee, J. Lok, C.L.K. Lam, E.Y.F. Wan, J. Quan Tags: Original Article Source Type: research
A Multicentric, Retrospective, Real-world Study on Immune-related Adverse Events in Patients with Advanced Non-small Cell Lung Cancers Treated with Pembrolizumab Monotherapy
We present 7 years of clinical experience with single-agent pembrolizumab immune checkpoint inhibitor immunotherapy in non-small cell lung cancers (NSCLC) from four UK cancer centres. This multi-institutional retrospective cohort study included 226 metastatic NSCLC patients. Outcomes were number and severity of immune-related adverse events (irAEs), median progression-free survival (mPFS) and median overall survival (mOS).Within our cohort, 119/226 (53%) patients developed irAEs. Of these, 54/119 (45%) experienced irAEs affecting two or more organ systems. (Source: Clinical Oncology)
Source: Clinical Oncology - January 15, 2024 Category: Radiology Authors: A. Lerner, A.J.X. Lee, H. Yan, J. Van Griethuysen, A.D. Bartlett, M. Veli, Y. Jiang, M. Luong, N. Naban, C. Kane, J. Conibear, D. Papadatos-Pastos, T. Ahmad, D. Chao, G. Anand, U.S. Asghar Tags: Original Article Source Type: research
Will Immune Checkpoint Inhibitors Allow the Non-operative Management of Mismatch Repair-deficient Colorectal Cancer to Become a Standard of Care?
(Source: Clinical Oncology)
Source: Clinical Oncology - January 13, 2024 Category: Radiology Authors: H. Sinclair, T. Ranji, D.C. Gilbert Tags: Editorial Source Type: research
Pharyngeal Constrictor Dose –Volume Histogram Metrics and Patient-reported Dysphagia in Head and Neck Radiotherapy
Head and neck radiotherapy long-term survival continues to improve and the management of long-term side-effects is moving to the forefront of patient care. Dysphagia is associated with dose to the pharyngeal constrictors and can be measured using patient-reported outcomes to evaluate its effect on quality of life. The aim of the present study was to relate pharyngeal constrictor dose –volume parameters with patient-reported outcomes to identify prognostic dose constraints. (Source: Clinical Oncology)
Source: Clinical Oncology - January 10, 2024 Category: Radiology Authors: O. Paetkau, S. Weppler, J. Kwok, H.C. Quon, C. Gomes da Rocha, W. Smith, E. Tchistiakova, C. Kirkby Tags: Original Article Source Type: research
Commentary on the New National Institute for Health and Care Excellence Guideline for Metastatic Spinal Cord Compression
(Source: Clinical Oncology)
Source: Clinical Oncology - January 10, 2024 Category: Radiology Authors: S. Growcott, E. Renninson, L. Rayner, J. McKeon, G. Ayre, C. Comins, A. Challapalli, W. Owadally, M. Beasley, L. Hawley, S. Hilman, T. Strawson-Smith, A. Bahl Tags: Letter Source Type: research
