Impact of COVID-19 Pandemic on Radiotherapy Interruptions and Patient Outcomes
(Source: Clinical Oncology)
Source: Clinical Oncology - June 5, 2023 Category: Radiology Authors: Chen-Xiong Hsu, Tien-Chi Li Tags: Letter Source Type: research
Differential Response of Pelvic Bone Marrow FDG Uptake in Patients Receiving Concurrent Chemoradiotherapy
Irradiation of pelvic bone marrow (PBM) at the level of the typical low dose bath of intensity-modulated radiotherapy delivery (10 –20 Gy) is associated with an increased risk of haematological toxicity, particularly when combined with concurrent chemotherapy. Although sparing of the whole of the PBM at a 10–20 Gy dose level is unachievable, it is known that PBM is divided into haematopoietically active and inactive regions that are identifiable based on the threshold uptake of [18F]-fluorodeoxyglucose (FDG) seen on positron emission tomography-computed tomography (PET-CT). (Source: Clinical Oncology)
Source: Clinical Oncology - June 5, 2023 Category: Radiology Authors: Maxwell Robinson, Rebecca Muirhead, Daniel R. McGowan, Kwun-Ye Chu, Clare Jacobs, Maria A. Hawkins Tags: Original Article Source Type: research
Is it doable to pick a few good oranges out of a full rotten basket: masticator space involvement in locally advanced oral cavity cancers
(Source: Clinical Oncology)
Source: Clinical Oncology - June 5, 2023 Category: Radiology Authors: D. Kukreja, M. Verma, M.L.B. Bhatt Tags: Letter Source Type: research
Combining Stereotactic Radiotherapy and Conventional Radiotherapy for Peripheral Locally Advanced Lung Cancer
(Source: Clinical Oncology)
Source: Clinical Oncology - June 5, 2023 Category: Radiology Authors: Jacques Boutros, Nicolas Martin, Josiane Otto, Charles-Hugo Marquette, Baptiste Lhomel, Arash O. Naghavi, Renaud Schiappa, Pierre-Yves Bondiau, Jerome Doyen Tags: Letter Source Type: research
National Audit of Care at the End of Life: Dying in Hospitals
When asked, most of us might say that, when the time comes, we would wish to die at home. Much has been done to enable this, particularly over the last few years [1]. However, nearly half of those in the UK currently die in acute hospitals [2]. For many this is the preferred place given their circumstances at the time, for others it may reflect a lack of support appropriate to their needs elsewhere, or the time available to plan otherwise has proved too short. (Source: Clinical Oncology)
Source: Clinical Oncology - June 1, 2023 Category: Radiology Authors: S. Kite, E. Rees Tags: Editorial Source Type: research
Spinal Reirradiation-Mediated Myelopathy: A Systematic Review and Meta-Analysis
Reirradiation of the spine is carried out in 42% of patients who do not respond to treatment or have recurrent pain. However, there are few studies and data on the effect of reirradiation of the spine and the occurrence of acute and chronic side-effects caused by reirradiation, such as myelopathy, in these patients. This meta-analysis aimed to determine the safe dose in terms of biological effective dose (BED), cumulative dose and dose interval between BED1 and BED2 to decrease or prevent myelopathy and pain control in patients undergoing radiation therapy in the spinal cord. (Source: Clinical Oncology)
Source: Clinical Oncology - June 1, 2023 Category: Radiology Authors: A. Amraee, M.R. Tohidkia, L. Darvish, A. Tarighatnia, N. Robatmili, A. Rahimi, N. Rezaei, F. Ansari, S.H. Teshnizi, A. Aghanejad Tags: Overview Source Type: research
Spinal Re-irradiation mediated myelopathy: A Systematic Review and Meta-Analysis
Reirradiation of the spine is carried out in 42% of patients who do not respond to treatment or have recurrent pain.However, there are few studies and data on the effect of reirradiation of the spine and the occurrence of acute and chronic side-effects caused by reirradiation, such as myelopathy, in these patients. This meta-analysis aimed to determine the safe dose in terms of biological effective dose (BED), cumulative dose and dose interval between BED1 and BED2 to decrease or prevent myelopathy and pain control in patients undergoing radiation therapy in the spinal cord. (Source: Clinical Oncology)
Source: Clinical Oncology - June 1, 2023 Category: Radiology Authors: Azadeh Amraee, Mohammad Reza Tohidkia, Leili Darvish, Ali Tarighatnia, Nasrin Robatmili, Atena Rahimi, Narges Rezaei, Farzaneh Ansari, Saeed Hosseini Teshnizi, Ayuob Aghanejad Tags: Overview Source Type: research
National Audit of Care at the End of Life (NACEL): Dying in Hospitals
(Source: Clinical Oncology)
Source: Clinical Oncology - June 1, 2023 Category: Radiology Authors: Suzanne Kite, Elizabeth Rees, Ann Henry Tags: Editorial Source Type: research
Challenges in the Sustainability of Brachytherapy Service in Contemporary Radiotherapy
[AQ1]Brachytherapy has a long history of delivering a highly conformal radiation dose to the target volume with sparing of adjacent normal tissue and has an irreplaceable role in certain cancers, such as cervical and prostate cancers. There have been futile attempts to replace brachytherapy with other radiation techniques. Despite that there are multifaceted challenges in preserving this dying art, from establishment, to a trained workforce, to maintenance of the equipment and source replacement costs. (Source: Clinical Oncology)
Source: Clinical Oncology - May 30, 2023 Category: Radiology Authors: M. Swain, A. Budrukkar, A. Rembielak, T. Kron, J.P. Agarwal Source Type: research
A Narrative Synthesis of Literature on the Barriers to Timely Diagnosis and Treatment of Cancer in Sub-Saharan Africa
Poor cancer survival outcomes in sub-Saharan Africa (SSA) have been linked to delays in diagnosis and treatment. Here we present a detailed overview of the qualitative literature evaluating the barriers to receiving timely diagnosis and treatment of cancer in SSA. The [AQ1]PubMed, EMBASE, CINAHL, PsycINFO databases were searched to identify qualitative studies reporting on barriers to timely diagnosis of cancer in SSA published between 1995 and 2020. A systematic review methodology was applied, including quality assessment and narrative data synthesis. (Source: Clinical Oncology)
Source: Clinical Oncology - May 30, 2023 Category: Radiology Authors: M. Mwamba, D.C. Lombe, S. Msadabwe, V. Bond, M. Simwinga, A. Sentoogo Ssemata, R. Muhumuza, J. Seeley, A.D. Mwaka, A. Aggarwal Tags: Overview Source Type: research
Variation in rates of post-mastectomy radiotherapy among women with early invasive breast cancer in England and Wales: a population-based cohort study
This study examined whether patterns of post-mastectomy radiotherapy (PMRT) among women with early invasive breast cancer (EIBC) varied within England and Wales and explored the role of different patient factors in explaining any variation. (Source: Clinical Oncology)
Source: Clinical Oncology - May 30, 2023 Category: Radiology Authors: Katie Miller, Melissa Ruth Gannon, Jibby Medina, Karen Clements, David Dodwell, Kieran Horgan, Min Hae Park, David Alan Cromwell Tags: Original Article Source Type: research
The Clinicopathological Characteristics of POLE-mutated Colorectal Cancer and the Prognostic Value of POLE Status
Sir — Colorectal cancer (CRC) is one of the major causes of cancer-related morbidity and mortality worldwide [1]. The Cancer Genome Atlas first identified the molecular cohort of POLE-mutated (POLEmut) in CRC [2]. It has been reported that patients with endometrial cancer and glioblastoma harbouring P OLEmut exhibited excellent prognosis [3,4]. In addition, an extraordinary response to immune checkpoint inhibitor was found in POLEmut endometrial cancers [5]. However, the clinicopathological characteristics and clinical outcomes of POLEmut CRC remain unclear. (Source: Clinical Oncology)
Source: Clinical Oncology - May 29, 2023 Category: Radiology Authors: Q. Wu, Y. Luo, S. Zhang, X. Xie Tags: Letter Source Type: research
Assessing Equity of Access to Proton Beam Therapy: a Literature Review
Proton beam therapy (PBT) is one of the most advanced radiotherapy technologies, with growing evidence to support its use in specific clinical scenarios and exponential growth of demand and capacity worldwide over the past few decades. However, geographical inequalities persist in the distribution of PBT centres, which translate into variations in access and use of this technology. The aim of this work was to look at the factors that contribute to these inequalities, to help raise awareness among stakeholders, governments and policy makers. (Source: Clinical Oncology)
Source: Clinical Oncology - May 29, 2023 Category: Radiology Authors: S. Gaito, M.C. Aznar, N. Burnet, A. Crellin, A. France, D. Indelicato, K. Kirkby, S. Pan, G. Whitfield, E. Smith Tags: Overview Source Type: research
The clinicopathological characteristics of POLE-mutated colorectal cancer and prognostic value of POLE status
(Source: Clinical Oncology)
Source: Clinical Oncology - May 29, 2023 Category: Radiology Authors: Qing Wu, Yang Luo, Shu Zhang, Xianhe Xie Tags: Letter Source Type: research
Regarding ‘Impact of the COVID-19 Outbreak on Cancer Staging in Brazil’: Navigating the Impact of the Pandemic on Neuro-oncology Procedures
(Source: Clinical Oncology)
Source: Clinical Oncology - May 22, 2023 Category: Radiology Authors: Lucas Piason de Freitas Martins, Vanessa Emanuelle Cunha Santos, Isabela Mascarenhas de Andrade, N ícollas Nunes Rabelo Tags: Letter Source Type: research
