Tissue is the Issue: Current Status of Image-guided Biopsy
(Source: Clinical Oncology)
Source: Clinical Oncology - December 4, 2023 Category: Radiology Authors: K. Odedra, S. Wadhwani Source Type: research

Prospective Longitudinal Assessment of Quality of Life After Stereotactic Ablative Radiotherapy For Oligometastases: Analysis of the Population-Based SABR-5 Phase II Trial
To evaluate longitudinal patient-reported quality of life (QoL) in patients treated with stereotactic ablative radiotherapy (SABR) for oligometastases. (Source: Clinical Oncology)
Source: Clinical Oncology - December 3, 2023 Category: Radiology Authors: Ella Mae Cruz-Lim, Benjamin Mou, Sarah Baker, Gregory Arbour, Kelsey Stefanyk, Will Jiang, Mitchell Liu, Alanah Bergman, Devin Schellenberg, Abraham Alexander, Tanya Berrang, Andrew Bang, Nick Chng, Quinn Matthews, Hannah Carolan, Fred Hsu, Stacy Miller, Tags: Original Article Source Type: research

Clinical Experience of Axillary Radiotherapy for Node-positive Breast Cancer
Patients with breast cancer who have positive lymph nodes are currently recommended axillary node clearance (ANC) or regional nodal irradiation (RNI). ANC is associated with complications such as lymphoedema, brachial plexopathy and shoulder stiffness. The AMAROS Group showed RNI to be non-inferior to ANC with regards to survival and recurrence, and with a better quality of life. We conducted a large real-world population study to show our centre ’s experience with the use of RNI and to contribute to the current discussion around the management of node-positive breast cancer. (Source: Clinical Oncology)
Source: Clinical Oncology - November 27, 2023 Category: Radiology Authors: S. Anderson, A.L. Peters, G. Lumsden, A. Alhasso, D. Cartwright, O. O ’Brien, H. Marashi Tags: Original Article Source Type: research

Involved-site Radiotherapy Delineation Dilemmas in the Treatment of Adult Hodgkin Lymphoma: Turkish Society for Radiation Oncology Hematological Oncology, Pediatric Oncology and TBI Study Group Case-based Questionnaire Review (TROD 03-005)
The International Lymphoma Radiation Oncology Group (ILROG) defined involved-site radiotherapy (ISRT) guidelines. These rules offer a certain variability that allows for autonomous decision-making in diverse clinical settings. However, this flexibility also gives rise to conflicts about the selection of treatment fields in the daily decision-making process. The aim of this study was to show the extent of interobserver variability when ILROG-ISRT recommendations were used in different clinical scenarios. (Source: Clinical Oncology)
Source: Clinical Oncology - November 27, 2023 Category: Radiology Authors: M.T. Yilmaz, S. Kamer, F. Agaoglu, K.M. Hayran, F. Yildiz Tags: Original Article Source Type: research

Dose to Organ at Risk and its Characteristic Variation with the Clinically Used Different Prescription Levels for Early-stage Left-sided Breast Cancer
To evaluate the organ at risk (OAR) dose and its characteristic variation with different clinically usable prescription doses (RxD) for breast and chest wall radiotherapy in patients with early-stage left-sided breast cancer. (Source: Clinical Oncology)
Source: Clinical Oncology - November 24, 2023 Category: Radiology Authors: S. Haldar, B. Sarkar, A. Dixit Tags: Original Article Source Type: research

Image-guided Ablative Procedures
Various image-guided ablative procedures include chemical and thermal ablation techniques and irreversible electroporation. These have been used for curative intent for small tumours and palliative intent for debulking, immunogenicity and pain control. Understanding these techniques is critical to avoiding complications and achieving superior clinical outcomes. Additionally, combination with immunotherapy and chemotherapies is rapidly evolving. There are numerous opportunities in interventional radiology to advance ablation techniques and seamlessly integrate into current treatment regimens for both benign and malignant tu...
Source: Clinical Oncology - November 21, 2023 Category: Radiology Authors: R. Dai, R. Uppot, R. Arellano, S. Kalva Tags: Overview Source Type: research

Cell-free DNA Testing in Lung Cancer Patients Improves National Health Service Real-world Result Turnaround Time and Treatment Initiation for Tumours with Targetable Alterations by 4 Weeks
Sir — Lung cancer tumour profiling is an essential component in the initial assessment of advanced lung cancers and is usually performed on tumour biopsy samples using next-generation sequencing (NGS) [1]. Cell-free DNA (cfDNA) testing has emerged as a fast adjunct to biopsy profiling in multiple tumo ur types, including lung cancer. However, it is not routinely used in the UK National Health Service (NHS) in the work up of lung cancer patients [2]. Here we present our real-world use results from a single NHS cancer centre. (Source: Clinical Oncology)
Source: Clinical Oncology - November 20, 2023 Category: Radiology Authors: D.M. Favara, T. Verissimo, F. McCaughan Tags: Letter Source Type: research

Online Adaptive Magnetic Resonance-guided Radiation Therapy for Gynaecological Cancers: Preliminary Results of Feasibility and Outcome
To present the preliminary results on the clinical utilisation of an online daily adaptive magnetic resonance-guided radiation therapy (MRgRT) for various gynaecological cancers. (Source: Clinical Oncology)
Source: Clinical Oncology - November 20, 2023 Category: Radiology Authors: G. Ugurluer, T.Z. Mustafayev, G. Gungor, U. Abacioglu, B. Atalar, E. Ozyar Tags: Original Article Source Type: research

cfDNA testing in lung cancer patients improves NHS real-world result turnaround time and treatment initiation for tumours with targetable alterations by 4 weeks
(Source: Clinical Oncology)
Source: Clinical Oncology - November 20, 2023 Category: Radiology Authors: D.M. Favara, T. Verissimo, Frank McCaughan Tags: Letter Source Type: research

RCR Meetings
(Source: Clinical Oncology)
Source: Clinical Oncology - November 16, 2023 Category: Radiology Source Type: research

OncoFlash – Research Updates in a Flash! (December 2023 edition)
Re-irradiation in clinical practice: results of an international patterns of care survey within the framework of the ESTRO-EORTC E2-RADIatE platform. Willman, J. et  al. Radiother Oncol, 2023. [1]. (Source: Clinical Oncology)
Source: Clinical Oncology - November 16, 2023 Category: Radiology Authors: C. Crockett, R. Sim ões Source Type: research

A Neural Network-based Method for Predicting Dose to Organs at Risk in Intensity-modulated Radiotherapy for Nasopharyngeal Carcinoma
A neural network method was used to establish a dose prediction model for organs at risk (OARs) during intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC). (Source: Clinical Oncology)
Source: Clinical Oncology - November 16, 2023 Category: Radiology Authors: Huai-wen Zhang, Hao-wen Pang, You-hua Wang, Wei Jiang Tags: Original Article Source Type: research

Association between Sarcopenia and Survival in Patients Undergoing Gamma Knife Surgery for Brain Metastasis from Breast Cancer: a Retrospective Single-centre Cohort Study
Many recent studies related to cancer surgery have reported that sarcopenia influences mortality in surgical patients. However, few comprehensive studies have examined the associations between sarcopenia and short- and long-term surgical outcomes of metastatic cancer, especially breast cancer with brain metastasis. In the present study, we investigated the association between sarcopenia and mortality in patients who underwent gamma knife radiosurgery (GKRS) for brain metastasis with breast cancer. (Source: Clinical Oncology)
Source: Clinical Oncology - November 16, 2023 Category: Radiology Authors: Ji-Hoon Sim, Young-Hoon Kim, Sangho Lee, Hee-Sun Park, Won Uk Koh, Dong-Min Jang, Woo-Jong Choi Tags: Original Article Source Type: research

Efficacy and Safety of Programmed Death-1 (PD-1)/Programmed Death-Ligand 1 (PD-L1) Checkpoint Inhibitors in Patients with Metastatic Castration-resistant Prostate Cancer: a Systematic Review and Meta-analysis
The aim of this systematic review with meta-analysis was to evaluate the efficacy and safety of programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) checkpoint inhibitors in patients with metastatic castration-resistant prostate cancer (mCRPC). (Source: Clinical Oncology)
Source: Clinical Oncology - November 15, 2023 Category: Radiology Authors: Xuwei Hong, Yuanfeng Zhang, Zepai Chi, Qingchun Xu, Weiqiang Lin, Yueying Huang, Yonghai Zhang, Tianxin Lin Tags: Original Article Source Type: research

Instant Oncology
The author declares no conflicts of interest. (Source: Clinical Oncology)
Source: Clinical Oncology - November 14, 2023 Category: Radiology Authors: L. Wang Tags: Editorial Source Type: research