Radiosensitising Effects of Metformin Added to Concomitant Chemoradiotherapy with Cisplatin in Cervical Cancer

The role of metformin on the radiosensitising effect of cisplatin is not clear. Here we investigated the radiosensitising effect of metformin alone and combined with cisplatin in HeLa cells, as well as the implications of the adenosine monophosphate-activated protein kinase (AMPK) pathway on the radiosensitising effect.

Source: Clinical Oncology - September 1, 2023 Category: Radiology Authors: C.S. Beduk Esen, M.E. Gedik, H. Canpinar, F.Y. Yedekci, F. Yildiz, G. Gunaydin, M. Gultekin Tags: Original Article Source Type: research