Surveillance and Deregulated Pathways in Oral Merkel Cell Carcinoma

Sir — Merkel cell carcinoma (MCC) is an infrequent and incredibly destructive cutaneous neuroendocrine tumour. The tumour cells include neurosecretory granules, which are similar to those found in healthy Merkel cells [1]. MCC commonly manifests as an erythematous lesion in the dermal region of skin t hat is expanding quickly [2]. Rapid systemic tumour progression is also present, together with rapid local growth. The liver, bone and brain are distant organs where MCC frequently metastasises [3].
Source: Clinical Oncology - Category: Radiology Authors: Tags: Letter Source Type: research