When behaviour meets biology: if obesity is a chronic medical disease what is obesity management?
(Source: Clinical Obesity)
Source: Clinical Obesity - February 16, 2021 Category: Eating Disorders & Weight Management Authors: M. Vallis, D. Macklin Tags: Commentary Source Type: research

Bioelectrical impedance analysis for assessment of body composition in infants and young children ‐A systematic literature review
SummaryBioelectrical impedance analysis (BIA) is an easy to use, portable tool, but the accuracy of the technique in infants and young children (<24  months) remains unclear. A systematic literature review was conducted to identify studies that have developed and validated BIA equations in this age group. MEDLINE, Scopus, EMBASE, and CENTRAL were searched for relevant literature published up until June 30, 2020, using terms related to bioelect rical impedance, body composition, and paediatrics. Two reviewers independently screened studies for eligibility, resulting in 15 studies that had developed and/or validated equ...
Source: Clinical Obesity - February 10, 2021 Category: Eating Disorders & Weight Management Authors: Jaz Lyons ‐Reid, José G. B. Derraik, Leigh C. Ward, Mya‐Thway Tint, Timothy Kenealy, Wayne S. Cutfield Tags: Review Source Type: research

Costs of the COVID ‐19 pandemic associated with obesity in Europe: A health‐care cost model
This study reveals that excess weight contributes disproportionally to the costs of COVID ‐19. This might reflect that overweight and obesity caused the COVID‐19 pandemic to result in more severe outcomes for citizens and higher secondary care costs throughout Europe. (Source: Clinical Obesity)
Source: Clinical Obesity - February 8, 2021 Category: Eating Disorders & Weight Management Authors: Sebastien Czernichow, Stephen C. Bain, Matthew Capehorn, Mette B øgelund, Maria Elmegaard Madsen, Cecilie Yssing, Annabell Cajus McMillan, Ana‐Paula Cancino, Ulrik Haagen Panton Tags: Original Research Article Source Type: research

Substance use, mental health and weight ‐related behaviours during the COVID‐19 pandemic in people with obesity
SummaryStudies have shown the negative impact of COVID ‐19 lockdown orders on mental health and substance use in the general population. The aim of this study was to examine the impact of the COVID‐19 pandemic onsubstance use, mental health and weight‐related behaviors in a sample of adults with obesity after lockdown orders were lifted (June‐Se ptember 2020). A retrospective medical chart review identified patients with obesity from one university‐based obesity medicine clinic, and two metabolic and bariatric surgery (MBS) practices. Patients who completed an online survey from June 1, 2020 to September 30, 2020...
Source: Clinical Obesity - February 4, 2021 Category: Eating Disorders & Weight Management Authors: Jaime P. Almandoz, Luyu Xie, Jeffrey N. Schellinger, M. Sunil Mathew, Nora Bismar, Ashley Ofori, Sachin Kukreja, Benjamin Schneider, Denise Vidot, Sarah E. Messiah Tags: Original Research Article Source Type: research

Efficacy and safety of glucagon ‐like peptide‐1/glucagon receptor co‐agonist JNJ‐64565111 in individuals with obesity without type 2 diabetes mellitus: A randomized dose‐ranging study
SummaryIndividuals with obesity have a heightened risk of developing serious comorbidities, and pharmacological treatments for people with obesity are limited. This phase 2 study assessed the safety and efficacy of JNJ ‐64565111, a dual agonist of glucagon‐like peptide‐1 and glucagon receptors, in individuals with class II/III obesity without type 2 diabetes. In this randomized, double‐blind, placebo‐controlled and open‐label active‐controlled, parallel‐group, multicentre study, participants aged 1 8 to 70 years with a body mass index of 35 to 50 kg/m2 and stable weight were randomly assigned in a 1:1:2...
Source: Clinical Obesity - January 21, 2021 Category: Eating Disorders & Weight Management Authors: Maria Alba, Jaqueline Yee, Mary Ellen Frustaci, Mahesh N. Samtani, Penny Fleck Tags: Original Research Article Source Type: research

Efficacy and safety of glucagon ‐like peptide‐1/glucagon receptor co‐agonist JNJ‐64565111 in individuals with type 2 diabetes mellitus and obesity: A randomized dose‐ranging study
SummaryWeight loss has been shown to improve metabolic parameters and cardiovascular risk in people with type 2 diabetes mellitus (T2DM). This phase 2 study evaluated the safety and efficacy of JNJ ‐64565111, a dual agonist of GLP‐1 and glucagon receptors, in individuals with T2DM and class II/III obesity. In this randomized, double‐blind study, participants with T2DM (HbA1c 6.5%‐9.5%), body mass index of 35 to 50 kg/m2 and stable weight were randomly assigned (1:1:1:1) to placebo or JNJ ‐64565111 (5.0 mg, 7.4 mg or 10.0 mg). The primary endpoint was percent change from baseline in body weight at week 12. Of 19...
Source: Clinical Obesity - January 21, 2021 Category: Eating Disorders & Weight Management Authors: Nicholas A. Di Prospero, Jaqueline Yee, Mary E. Frustaci, Mahesh N. Samtani, Maria Alba, Penny Fleck Tags: Original Research Article Source Type: research

“I don't want them to think that what they said matters”: How treatment ‐ seeking adolescents with severe obesity cope with weight‐based victimization
This study aims to explore how treatment‐seeking adolescents with severe obesity cope with weight‐based victimization. This was a qualitative research study using an interpretive phenomenological analytic approach. One‐on‐one semi structured interviews were completed with 19 adolescents (63% female) enrolled in a weight management program. The interviews were transcribed and sequentially analysed until data saturatio n was attained. The majority of participants (89.5%) described being a victim of weight‐based victimization and highlighted a significant emotional toll. Two key themes were identified that captured ...
Source: Clinical Obesity - January 15, 2021 Category: Eating Disorders & Weight Management Authors: Órla Walsh, Elizabeth Dettmer, Andrea Regina, Linlei Ye, Jennifer Christian, Jill Hamilton, Alene Toulany Tags: Original Research Article Source Type: research

Associations between number of siblings, birth order, eating rate and adiposity in children and adults
SummaryEating quickly is associated with eating larger amounts at mealtimes and faster eaters tend to have a higher BMI. Evidence suggests that sibling structure influences the development of childhood eating behaviours. We hypothesized that number of siblings and birth order might play a role in the development of eating rate. In two UK studies, children in Bristol (n = 132; Study 1) and adults and children in London (adultsn = 552, childrenn = 256; Study 2) reported their eating rate, number of siblings, and birth order. A BMI measurement was obtained and in Study 2 waist circumference was recorded. Ordered logistic regr...
Source: Clinical Obesity - January 12, 2021 Category: Eating Disorders & Weight Management Authors: Christina Potter, E. Leigh Gibson, Danielle Ferriday, Rebecca L. Griggs, Christle Coxon, Margot Crossman, Ray Norbury, Peter J. Rogers, Jeffrey M. Brunstrom Tags: Original Research Article Source Type: research

Glucagon ‐like peptide‐1 receptor agonists in the era of COVID‐19: Friend or foe?
SummaryThe aim of the present manuscript is to discuss on potential pros and cons of glucagon ‐like peptide‐1 receptor agonists (GLP‐1RAs) as glucose‐lowering agents during COVID‐19 pandemic, and what is more to evaluate them as potential candidates for the treatment of patients, affected by COVID‐19 infection, with or even without diabetes mellitus type 2. Besides being importan t glucose‐lowering agents, GLP‐1RAs pose promising anti‐inflammatory and anti‐obesogenic properties, pulmonary protective effects, as well as beneficial impact on gut microbiome composition. Hence, taking everything previously ...
Source: Clinical Obesity - January 10, 2021 Category: Eating Disorders & Weight Management Authors: Andrej Belan čić, Andrea Kresović, Marija Troskot Dijan Tags: Review Source Type: research

Identifying meaningful dietary intake and physical activity questions for individual and population health
We present a parsimonious and reliable six ‐question scale of physical activity and dietary behaviours for research settings, as well as a three‐question scale for clinical settings. We demonstrate a robust relationship between these measures and obesity. Additionally, we present evidence that these measures may serve as a useful red fla g for patients before they develop obesity. We provide a concise and useful tool for assessing patients' physical activity and dietary behaviours in a variety of research settings. We also highlight the importance of incorporating this tool into the clinical intake flow for inclusion i...
Source: Clinical Obesity - January 7, 2021 Category: Eating Disorders & Weight Management Authors: Jennifer Bennett Shinall, David G. Schlundt, Mikaela H. Sullivan, Hannah J. Frank, Eli K. Po'e, Evan C. Sommer, Kemberlee R. Bonnet, Laura E. Burgess, Shari L. Barkin, Kelly L. Haws Tags: Original Research Article Source Type: research