Influence of prenatal perceived stress on postpartum weight retention is mediated by high gestational weight gain in women with overweight
This study examined: (a) pre‐pregnancy weight status (ie, normal, overweight, obesity) differences in PPWR and its psychosocial determinants (perceived s ocial support, perceived stress, depression) in women with excessive GWG (ie, above 2009 Institute of Medicine guidelines); and (b) whether GWG mediated associations between psychosocial determinants and PPWR. Women (N = 1352) reported third trimester perceived social support, perceived stress, and depressive symptoms, GWG, and 6‐ and 12‐month PPWR via telephone interviews. Multivariate ANOVA analyses showed women with normal weight had higher 6‐month PPWR than wo...
Source: Clinical Obesity - March 8, 2021 Category: Eating Disorders & Weight Management Authors: Krista S. Leonard, Elizabeth L. Adams, Jennifer S. Savage, Ian M. Paul, Jennifer L. Kraschnewski, Krista L. Pattison, Kristen H. Kjerulff, Danielle Symons Downs Tags: Original Research Article Source Type: research

A systematic review of randomized controlled trials of dietary interventions for weight loss in adults in the Middle East and north Africa region
SummaryThe prevalence and incidence of obesity, and associated complications, such as type 2 diabetes, in the Middle East and north Africa (MENA) region rank among the highest in the world. Little is known about the effectiveness of dietary weight loss interventions conducted in the MENA region. We conducted a systematic review of randomized clinical trials aiming to assess the effectiveness of dietary interventions for weight loss in the adult population originating from and residing in the MENA region. In accordance with PRISMA guidelines, PubMed, CINAHL, Cochrane, and EMBASE were systematically searched for randomized c...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Hadeel Zaghloul, Hadya Elshakh, Abdullah Elzafarany, Odette Chagoury, Barbara McGowan, Shahrad Taheri Tags: REVIEW ARTICLE Source Type: research

The safety and efficacy of supervised exercise on pregnant women with overweight/obesity: A systematic review and meta ‐analysis of randomized controlled trials
SummaryBehavioural modification through physical activity and dietary counselling has been shown to have beneficial effects on pregnant women with overweight/obesity. Whether exercise alone with supervision (ie, supervised exercise) may also benefit for pregnant women with overweight/obesity is still unknown. This systematic review and meta ‐analysis aimed to determine the safety and efficacy of supervised exercise on pregnant women with overweight/obesity. PubMed, Cochrane library, Embase (Ovid), CINAHL (EBSCO), and Web of Science were used to search publications using a combination of main keywords “obesity”, “ex...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Harry Freitag Luglio Muhammad, Adriyan Pramono, Muhammad Nurhadi Rahman Tags: REVIEW ARTICLE Source Type: research

Glucagon ‐like peptide‐1 receptor agonists in the era of COVID‐19: Friend or foe?
SummaryThe aim of the present manuscript is to discuss on potential pros and cons of glucagon ‐like peptide‐1 receptor agonists (GLP‐1RAs) as glucose‐lowering agents during COVID‐19 pandemic, and what is more to evaluate them as potential candidates for the treatment of patients, affected by COVID‐19 infection, with or even without diabetes mellitus type 2. Besides being importan t glucose‐lowering agents, GLP‐1RAs pose promising anti‐inflammatory and anti‐obesogenic properties, pulmonary protective effects, as well as beneficial impact on gut microbiome composition. Hence, taking everything previously ...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Andrej Belan čić, Andrea Kresović, Marija Troskot Dijan Tags: REVIEW ARTICLE Source Type: research

Issue Information
(Source: Clinical Obesity)
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Tags: ISSUE INFORMATION Source Type: research

Efficacy and safety of glucagon ‐like peptide‐1/glucagon receptor co‐agonist JNJ‐64565111 in individuals with type 2 diabetes mellitus and obesity: A randomized dose‐ranging study
SummaryWeight loss has been shown to improve metabolic parameters and cardiovascular risk in people with type 2 diabetes mellitus (T2DM). This phase 2 study evaluated the safety and efficacy of JNJ ‐64565111, a dual agonist of GLP‐1 and glucagon receptors, in individuals with T2DM and class II/III obesity. In this randomized, double‐blind study, participants with T2DM (HbA1c 6.5%‐9.5%), body mass index of 35 to 50 kg/m2 and stable weight were randomly assigned (1:1:1:1) to placebo or JNJ ‐64565111 (5.0 mg, 7.4 mg or 10.0 mg). The primary endpoint was percent change from baseline in body weight at week 12. Of 19...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Nicholas A. Di Prospero, Jaqueline Yee, Mary E. Frustaci, Mahesh N. Samtani, Maria Alba, Penny Fleck Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Efficacy and safety of glucagon ‐like peptide‐1/glucagon receptor co‐agonist JNJ‐64565111 in individuals with obesity without type 2 diabetes mellitus: A randomized dose‐ranging study
SummaryIndividuals with obesity have a heightened risk of developing serious comorbidities, and pharmacological treatments for people with obesity are limited. This phase 2 study assessed the safety and efficacy of JNJ ‐64565111, a dual agonist of glucagon‐like peptide‐1 and glucagon receptors, in individuals with class II/III obesity without type 2 diabetes. In this randomized, double‐blind, placebo‐controlled and open‐label active‐controlled, parallel‐group, multicentre study, participants aged 1 8 to 70 years with a body mass index of 35 to 50 kg/m2 and stable weight were randomly assigned in a 1:1:2...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Maria Alba, Jaqueline Yee, Mary Ellen Frustaci, Mahesh N. Samtani, Penny Fleck Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

“If you're offered help, take it”: A qualitative study examining bariatric patients' experience of telephone‐based cognitive behavioural therapy
SummaryThe increased recognition of patients' mental health needs after bariatric surgery has resulted in the emergence of accessible psychosocial interventions; however, there is a dearth of literature on patient experience and satisfaction with these interventions. We explored patients' perceptions and experiences of telephone ‐based cognitive behavioural therapy (Tele‐CBT) in this qualitative study. Ten participants from the Toronto Western Hospital Bariatric Surgery Program in Toronto, Canada who completed the Tele‐CBT (ClinicalTrials.gov Identifier: NCT02920112) were individually interviewed from November 2014 t...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Vincent A. Santiago, Stephanie E. Cassin, Susan Wnuk, Chau Du, Raed Hawa, Sagar V. Parikh, Sanjeev Sockalingam Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Intermittent and continuous energy restriction result in similar weight loss, weight loss maintenance, and body composition changes in a 6 month randomized pilot study
This study assessed changes in weight, body composition, and macronutrient intake for an IER and a continuous energy restriction (CONT) approach within a multicomponent weight management intervention. We randomized 35 adults with overweight/obesity (BMI = 31.2  ± 2.4 kg/m2) to CONT or IER for 24  weeks (12‐week weight loss intervention and 12 weeks of weight loss maintenance). Diets were delivered within a multimodal weight management program including weekly group meetings with a registered dietitian, increased physical activity, and a comprehensive lifestyle change program. Retentio n and adherence were simila...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Felicia L. Steger, Joseph E. Donnelly, Holly R. Hull, Xinyang Li, Jinxiang Hu, Debra K. Sullivan Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Costs of the COVID ‐19 pandemic associated with obesity in Europe: A health‐care cost model
This study reveals that excess weight contributes disproportionally to the costs of COVID ‐19. This might reflect that overweight and obesity caused the COVID‐19 pandemic to result in more severe outcomes for citizens and higher secondary care costs throughout Europe. (Source: Clinical Obesity)
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Sebastien Czernichow, Stephen C. Bain, Matthew Capehorn, Mette B øgelund, Maria Elmegaard Madsen, Cecilie Yssing, Annabell Cajus McMillan, Ana‐Paula Cancino, Ulrik Haagen Panton Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

A disability ‐based exploration of psychosocial barriers and enablers to accessing dental services for people with clinically severe obesity: A qualitative study
This study concluded that PwCSO face significant barriers to accessing dental servi ces across all six categories highlighted in the disability literature. The study findings provide valuable patient‐based information regarding the psychosocial barriers to accessing dental services, which are relevant for all healthcare professionals. The study reflected an increased need for pro motion of the dentist's role in obesity management and obesity‐related dental training, including familiarization with the biopsychosocial domains of obesity to reduce weight related stigma and discrimination, as an area for further study. The...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Zanab Malik, Alexander C. L. Holden, Woosung Sohn, Kathryn Williams Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Substance use, mental health and weight ‐related behaviours during the COVID‐19 pandemic in people with obesity
SummaryStudies have shown the negative impact of COVID ‐19 lockdown orders on mental health and substance use in the general population. The aim of this study was to examine the impact of the COVID‐19 pandemic onsubstance use, mental health and weight‐related behaviors in a sample of adults with obesity after lockdown orders were lifted (June‐Se ptember 2020). A retrospective medical chart review identified patients with obesity from one university‐based obesity medicine clinic, and two metabolic and bariatric surgery (MBS) practices. Patients who completed an online survey from June 1, 2020 to September 30, 2020...
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Authors: Jaime P. Almandoz, Luyu Xie, Jeffrey N. Schellinger, M. Sunil Mathew, Nora Bismar, Ashley Ofori, Sachin Kukreja, Benjamin Schneider, Denise Vidot, Sarah E. Messiah Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Issue Information
(Source: Clinical Obesity)
Source: Clinical Obesity - March 2, 2021 Category: Eating Disorders & Weight Management Tags: ISSUE INFORMATION Source Type: research

A service evaluation exploring the effectiveness of a locally commissioned tier 3 weight management programme offering face ‐to‐face, telephone and digital dietetic support
In this study, a service evaluation compared weight loss for adults with a BMI ≥ 45 kg/m2 or  ≥ 40 kg/m2 with a comorbidity, who were offered a non ‐randomized dietetic intervention through face‐to‐face, telephone, or digital support using the Oviva smartphone app as part of a tier 3 weight management programme. One hundred and sixty‐nine patients commenced the core programme. There were no significant differences in weight loss between patients receiving face‐to‐face (5.3 ± 5.5 kg [−4.1%]), telephone (−4 ± 5.3 kg [−3.4%]) and digital support (−6.1 ± 4.9 kg [−4.5%]) (P =...
Source: Clinical Obesity - February 18, 2021 Category: Eating Disorders & Weight Management Authors: Rosemary Huntriss, Matthew Haines, Lucy Jones, Danielle Mulligan Tags: Original Research Article Source Type: research