Issue Information
(Source: Clinical Obesity)
Source: Clinical Obesity - January 6, 2022 Category: Eating Disorders & Weight Management Tags: ISSUE INFORMATION Source Type: research

Translation and validation of the Greek version of the Modified Weight Bias Internalization Scale in an adult population
SummaryWeight bias internalization (WBI) has been identified as a global public health concern, which is associated with significant psychological and physical consequences. Despite increased interest in WBI worldwide, cross-cultural research is limited by the lack of availability of validated measures. The aim of the current study was therefore to translate into Greek and validate the Modified Weight Bias Internalization Scale (WBIS-M), the most widely used instrument in the measurement of WBI. An online convenience sample of 642 participants (364 women and 278 men) completed the Greek translation of the WBIS-M and valida...
Source: Clinical Obesity - December 30, 2021 Category: Eating Disorders & Weight Management Authors: Marios Argyrides, Zoe Charalambous, Elly Anastasiades, Katerina Michael Tags: Original Research Article Source Type: research

The application of body mass index ‐based eligibility criteria may represent an unjustified barrier to renal transplantation in people with obesity
SummaryThe prevalence of both obesity and end-stage kidney disease is increasing. In many centres, obesity is considered a relative contraindication to kidney transplantation due to an association with short- and longer-term adverse outcomes. This leads to delayed transplant waitlisting and longer organ waiting times for people with obesity. This review evaluates whether intentional pre-transplant weight loss in people with obesity improves kidney transplant outcomes. There are currently no data showing that non-surgical weight loss of 10% or more improves graft or patient survival over 4 –5 years. Outcomes from bariat...
Source: Clinical Obesity - December 29, 2021 Category: Eating Disorders & Weight Management Authors: Alanna Tan, Scott Wilson, Priya Sumithran Tags: Review Article Source Type: research

Heart valve surgery and the obesity paradox: A systematic review
SummaryObesity has been associated with increased incidence of comorbidities and shorter life expectancy, and it has generally been assumed that patients with obesity should have inferior outcomes after surgery. Previous literature has often demonstrated equivalent or even improved rates of mortality after cardiac surgery when compared to their lower-weight counterparts, coined the obesity paradox. Herein, we aim to review the literature investigating the impact of obesity on surgical valve interventions. PubMed and Embase were systematically searched for articles published from 1 January 2000 to 15 October 2021. A total o...
Source: Clinical Obesity - December 28, 2021 Category: Eating Disorders & Weight Management Authors: Ryaan EL ‐Andari, Sabin J. Bozso, Jimmy J. H. Kang, Alexandre M. A. Bedard, Corey Adams, Wei Wang, Jeevan Nagendran Tags: Review Article Source Type: research

Birth weight and prediabetes in a nationally representative sample of US adolescents
SummaryPrediabetes affects about 20% of adolescents in the United States. Previous studies have shown that low and high birth weight impairs glucose homeostasis in adults; however, limited research has examined this relationship in adolescents. To investigate association of birthweight with prediabetes in US adolescents using data from NHANES 2005 –2016 and examine whether sex and obesity moderate this relationship. Adolescents, aged 12–15 years without diagnosed/undiagnosed diabetes and extreme birthweight (n = 1396), were classified as low birth weight (LBW), normal birthweight (NBW) and high birth weight (HBW). ...
Source: Clinical Obesity - December 24, 2021 Category: Eating Disorders & Weight Management Authors: Namrata Sanjeevi, Jeanne H. Freeland ‐Graves Tags: Original Research Article Source Type: research

Pharmacotherapy of obesity in complex diseases
SummaryMore than 40% of adults in the United States suffer from obesity. Obesity is inextricably linked to many chronic illnesses like type-2 diabetes mellitus, hypertension, hyperlipidemia, heart disease, sleep apnea, stroke, and cancers. When used in combination with lifestyle modifications, pharmacotherapy has a vital role in treating obesity and improves short-term and long-term outcomes. A growing number of physicians are now interested in obesity medicine, and many of them are seeking guidance on how to treat complex patients with co-morbidities. This review provides a practical guide to the use of anti-obesity medic...
Source: Clinical Obesity - December 13, 2021 Category: Eating Disorders & Weight Management Authors: Vishnu Priya Pulipati, Silvana Pannain Tags: Review Source Type: research

Online survey on factors influencing patients' motivation to undergo bariatric surgery
SummaryGiven the worldwide increasing prevalence of severe obesity and considering the amount of scientific evidence demonstrating the beneficial effects of bariatric surgery (BS), it is surprising that only a fraction of patients with obesity undergo BS. We therefore conducted an anonymized online survey among individuals with a history of BS to understand factors influencing the deciding process leading to BS. Respondents were recruited on a voluntary basis from obesity-related social media groups between April and June 2020. The self-designed, non-validated questionnaire consisted of 20 questions and was open to any par...
Source: Clinical Obesity - December 8, 2021 Category: Eating Disorders & Weight Management Authors: Jeannette Widmer, Daniel Gero, Barbara Sommerhalder, Daniela Alceste, Ivana Raguz, Michele Serra, Ren é Vonlanthen, Marco Bueter, Andreas Thalheimer Tags: Original Research Article Source Type: research

Risk and protective factors of non ‐alcoholic fatty liver disease in paediatric obesity: A nationwide nested case–control study
SummaryNot all children with obesity carry a similar risk of non-alcoholic fatty liver disease (NAFLD). We investigated the effect of obesity severity, metabolic risk parameters, and obesity treatment outcome on later risk of NAFLD in paediatric obesity. We conducted a nested case –control study of children and adolescents enrolled in the Swedish Childhood Obesity Treatment Register (BORIS) (2001–2016). NAFLD was ascertained from the National Patient Register. Five controls per case were matched by sex and age at index date and at the obesity treatment initiation. Seventy -six pairs (n cases  = 76,n controls  = 241...
Source: Clinical Obesity - December 8, 2021 Category: Eating Disorders & Weight Management Authors: Resthie R. Putri, Thomas Casswall, Emilia Hagman Tags: Original Research Article Source Type: research

Metabolic inflexibility in youth with obesity: Is it a feature of obesity or distinctive of youth who are metabolically unhealthy?
SummaryIndividuals with obesity have metabolic inflexibility with diminished fasting fat oxidation and blunted increase in respiratory quotient (RQ) in insulin-stimulated states. However, it is unclear if metabolic inflexibility is a characteristic of obesity per se or is unique to youth who have metabolically unhealthy obesity (MUO) compared with metabolically healthy obesity (MHO). We investigated metabolic flexibility in youth with MUO, MHO and normal weight (NW) and compared their metabolic characteristics. Youth (n = 188) were divided, based on cut-off points for in vivo insulin sensitivity (IS) of adolescents with ...
Source: Clinical Obesity - December 3, 2021 Category: Eating Disorders & Weight Management Authors: Nour Y. Gebara, Joon Young Kim, Fida Bacha, SoJung Lee, Silva Arslanian Tags: Original Research Article Source Type: research

Patients' views and experiences of live supervised tele ‐exercise classes following bariatric surgery during the COVID‐19 pandemic: The BARI‐LIFESTYLE qualitative study
SummaryThe BARI-LIFESTYLE trial is a randomized controlled trial evaluating the efficacy of a post-surgery nutritional and behavioural tele-counselling, and supervised exercise programme to maximize the health benefits of bariatric surgery. Due to the coronavirus disease 2019 (COVID-19) pandemic, the in-person supervised exercise component had to be converted to remote tele-exercise. However, patients' acceptability of this method of exercise provision is unknown. Between 3 and 6  months following bariatric surgery, 13 adults participated in weekly, structured, 60-min supervised exercise classes delivered via Zoom by a tr...
Source: Clinical Obesity - November 30, 2021 Category: Eating Disorders & Weight Management Authors: Friedrich C. Jassil, Rebecca Richards, Alisia Carnemolla, Neville Lewis, Gemma Montagut ‐Pino, Helen Kingett, Jacqueline Doyle, Amy Kirk, Adrian Brown, Kusuma Chaiyasoot, Kalpana Devalia, Chetan Parmar, Rachel L. Batterham Tags: Original Research Article Source Type: research

Development of a weight bias reduction intervention for third ‐year nursing students
SummaryTo explore whether case-based learning will enhance a weight bias reduction (WBR) programme among nursing students to improve their attitudes and beliefs towards persons with obesity. A cluster-randomized controlled trial (CRT) among 13 medical-surgical clinical practicum groups consisting of six to eight third-year baccalaureate nursing students was conducted to compare a WBR training enhanced by case-based learning (WBR-I,n = 7) with a standard WBR control group (n = 6). All participants completed the Attitudes Towards Obese Persons (ATOP) and Beliefs About Obese Persons (BAOP) questionnaires before the random...
Source: Clinical Obesity - November 26, 2021 Category: Eating Disorders & Weight Management Authors: Tracy L. Oliver, Bing ‐Bing Qi, Lisa K. Diewald, Rebecca Shenkman, Peter G. Kaufmann Tags: Original Research Article Source Type: research

The role of cognitive flexibility in weight loss after severe obesity surgery —A retrospective study
SummaryCognitive flexibility (CF) is a fundamental skill for behavioural regulation and adaptation during the weight-loss process. Research suggests that bariatric surgery (BS) candidates underperform consistently in the Wisconsin Card Sorting Test (WCST), which is a neuropsychological instrument that measures this ability. The current study explored the predictive value of preoperative performance in WCST CF dimensions alongside relevant psychological factors on weight loss after BS. The sample comprised 100 female patients who underwent BS in a public hospital in Lisbon, Portugal. We collected data using the WCST, the Ho...
Source: Clinical Obesity - November 26, 2021 Category: Eating Disorders & Weight Management Authors: Pedro Santos Monteiro, Olga Rodrigues Ribeiro, Filipa Ribeiro Tags: Original Research Article Source Type: research

Preconception diabetes remission, a viable approach to reduce pregnancy risks in women with recent diagnosis of Type 2 diabetes: Case report and clinical discussion
SummaryThe prevalence of women diagnosed with Type 2 diabetes (T2D) at fertile age has been increasing over the last few decades, and pregnancy with T2D is associated with increased maternal and foetal risks. In the last few years, studies have shown that focusing on aggressive weight loss in individuals recently diagnosed with T2D can lead to diabetes remission. Here, we present a case report of a woman who achieved diabetes remission after massive weight loss and had an uncomplicated pregnancy. Diabetes remission before pregnancy could be offered to motivated women with T2D as a safe way to reduce the risks of pregnancy....
Source: Clinical Obesity - November 26, 2021 Category: Eating Disorders & Weight Management Authors: Bruno Halpern, Renata Bressan Pepe Tags: Case Report Source Type: research

Association of obesity with serum free fatty acid levels in individuals at different stages of prediabetes
This study included 5006 male participants (1779, 1025, 629, 874, and 699 with normal fasting glucose/normal glucose tolerance, isolated impaired fasting glucose [IFG], isolated impaired glucose tolerance [IGT], IFG plus IGT, and diabetes, respectively). Serum FFA levels were assessed before and 30, 60, and 120  min after glucose ingestion, and the total area under the FFA curve (AUCFFA) was calculated. Adipose insulin resistance index (adipo-IR) was assessed based on fasting FFA and insulin concentrations. Isolated IFG was associated with high fasting FFA levels (OR, 1.35;p <  0.001) and high adipo-IR (OR, 1.82;p...
Source: Clinical Obesity - November 25, 2021 Category: Eating Disorders & Weight Management Authors: Nobuo Sasaki, Ryo Maeda, Ryoji Ozono, Yukiko Nakano, Yukihito Higashi Tags: Original Research Article Source Type: research

Polysomnographic comparison of sleep in children with obesity and normal weight without suspected sleep ‐related breathing disorder
SummaryShort sleep and obstructive apneas/hypopneas have been shown to be associated with childhood obesity. Still, few studies have compared sleep in children with obesity, without suspected sleep disordered breathing and normal weight peers by objective sleep measures and compared results with subjective parent assessment of sleep. Children with obesity aged 7 –13 years (N = 44) and a matched group of normal weight children (N = 42) completed clinical polysomnography (Embla A10 Recording System). Parents scored their children's sleep on the Children's Sleep Habits Questionnaire (CSHQ). Mann–WhitneyU tests wer...
Source: Clinical Obesity - November 16, 2021 Category: Eating Disorders & Weight Management Authors: Yngvild S ørebø Danielsen, Hanna Flækøy Skjåkødegård, Bjørn Bjorvatn, Petur Benedikt Juliusson, Ståle Pallesen Tags: Original Research Article Source Type: research