Leptin as a prognostic marker of cancer cachexia
Rationale: Recently it has been postulated that adipose tissue-derived hormons may be involved in the pathophysiology of tumor cachexia.The aim of the study was to analyze the role of leptin and other previously established parameters of cachexia in pancreatic cancer (PC) patients as diagnostic and prognostic marker of cachexia. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: A. Saray, I. Tancica, S. Cato-Mehmedbasic, N. Zahiragic, N. Zubcevic Source Type: research
Nutrition impact symptoms are associated to quality of life in patients with lung cancer during 12 months of chemotherapy
Rationale: Patient reported outcome measures (PROMs) gain information about patients ’ symptoms and may facilitate targeted nutritional interventions. We aimed to explore the associations between Nutrition Impact Symptoms (NIS) and Quality of Life (QoL) in patients with lung cancer during 12 months of chemotherapy. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: K.G. Frederiksen, L. Aadal, C.G. Flores, S.L. Mikkelsen, G. Liposits, Ø. Irtun, M. Holst Source Type: research
Overall survival study of a 307 patients cohort treated in our institution for a gastro-intestinal cancer and undernutrition, 5 years after first inclusion
In this study, our objective was to determine whether overall survival at 5 years was influenced by the nutritional status and management of undernutrition. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: M. Mahmutovic, N. Michot, A. Malgras, A. Germain, A. Lambert, P.-L. Nguyen-Thi, D. Quilliot Source Type: research
Comprehensive evaluation the prognostic value of serum nutritional markers in cancer patients with cachexia
Rationale: Our objective is to comprehensively evaluate the prognostic value of three serum hepatic proteins including albumin, prealbumin, and transferrin in patients with cancer cachexia. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: J. Huang, X. Zhang, H. Shi, M. Cong Source Type: research
Energy efficiency of walking is not related to resting hypermetabolism in advanced cancer
Rationale: Resting hypermetabolism in advanced cancer may affect energy efficiency during physical activity, complicating total energy expenditure estimation. We studied the relationship between resting energy expenditure and walking efficiency, hypothesizing a higher energy cost with hypermetabolism. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: O. Wallengren, B.-M. Iresj ö, K. Lundholm Source Type: research
Overfeeding in critical illness: effect on minute volume and PaCO2
Rationale: It has been described that overfeeding was associated with increased CO2 production and as a consequence, increased PaCO2 and minute volume (MV). However, the day-by-day effect of energy amount administered on MV and PaCO2 has been poorly studied. We evaluated different levels of energy administration and their consequences on MV and PaCo2 in a large ICU population. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: O. Raphaeli, L. Statlander, S. Algrabli, D. Iluz, C. Ofir, P. Singer Source Type: research
Gastric residual volume as predictor of clinical outcomes in critically ill patients at nutritionday: A machine learning (ML) approach
This study investigated the prognostic ability of GRV levels in predicting clinical outcomes in critically ill patients. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: O. Raphaeli, L. Ben Yechiel, L. Statlander, I. Kagan, M. Hiesmayr, S. Tarantino, I. Worf, A. Knoetzl, P. Singer Source Type: research
Compromised muscle function and physical activity during recovery of sepsis in an ICU-acquired weakness translational pig model
Rationale: Sepsis is characterized by severe tissue breakdown in several organs, leading to long-term muscle weakness, fatigue, and reduced physical activity (ICU-Acquired Weakness). Use of a translational large animal model is essential to investigate the complex metabolic processes underlying compromised functional performance during recovery from sepsis. Therefore we studied skeletal muscle function in an instrumented clinical relevant Pseudomonas induced sepsis pig model by measuring muscle strength/ fatique, and home cage physical activity. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: G. A. Ten Have, P.P. Nghiem, M.L. Mackey, C. van Sas, S.A. Rice, M.P. Engelen, N.E. Deutz Source Type: research
CT-derived muscle but not fat area independently predicts mortality in COVID-19
Rationale: COVID-19 has demonstrated a highly variable disease course, from asymptomatic to severe illness and eventually death. Clinical parameters, as included in the 4C Mortality Score, can accurately predict mortality in COVID-19. Additionally, computed tomography (CT)-derived low muscle and high adipose tissue cross-sectional areas (CSA) have been associated with adverse outcomes in COVID-19. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: S.V. Bakel, H. Gietema, P. Stassen, H. Gosker, D. Gach, J.V.D. Bergh, F.V. Osch, A. Schols, R. Beijers Source Type: research
Association between total parenteral nutrition and blood stream infections among critical care COVID 19 patients: A prospective observational study
Rationale: Observational studies suggest a high incidence of Blood Stream Infections (BSI) among critical care patients receiving parenteral nutrition. The aim of this study was to observe BSI rates among critically ill COVID-19 patients, as well as to investigate the potential association with feeding practices. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: D. Karayiannis, K. Nikolakopoulou, S. Chaloulakou, A. Kardara, E. Jahaj, C. Liakopoulou, Z. Mastora Source Type: research
Multidisciplinary enteral feeding protocol: The effective improvement on nutritional and clinical outcomes in the neonatal intensive care unit
This study evaluated the impact of multidisciplinary enteral feeding protocol on nutrition and clinical outcomes including days with central line in neonatal intensive care unit (NICU). (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: S. Park, S. Kim, I. Park, Y. Oh, J. Kim Source Type: research
Muscle elasticity: A novel radiological marker for frailty assessment
This study aimed to evaluate the possible relationship between SWE-defined changes in muscle elasticity and frailty. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: A. Okyar Ba ş, H. Baş, M. Güner, S. Ceylan, M. koca, M. Hafızoğlu, Z. Şahiner, Y. Öztürk, B.B. Doğu, M.G. Halil, M. Cankurtaran, C. Balcı Source Type: research
Malnutrition prevalence according to glim and its feasibility in geriatric patients: A prospective cross-sectional study
Rationale: In 2019, the Global Leadership Initiative on Malnutrition (GLIM) suggested a 2-step diagnostic format for malnutrition including screening and diagnosis. Prospective validation and feasibility studies, using the complete set of the five GLIM criteria, are needed. Aims of this study were to assess feasibility of GLIM in geriatric patients. Furthermore, we evaluated how malnutrition prevalence varied with mode of screening. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: F. Ostonen Peelen, M. Enge, R. Lundsgaard Nielsen, A.M. Beck, A. Ödlund Olin, T. Cederholm, A.-M. Boström, I. Paur Source Type: research
Higher anticholinergic burden is associated with poor nutritional outcome
Rationale: Undernutrition and anticholinergic burden are common in older adults (1, 2). The present study aimed to evaluate the relationship between nutritional status and anticholinergic burden among older patients. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: Z. Ö. Özdemir, S. Ceylan, D. Karaduman, M. Güner, A. Okyar Baş, Z. Kahyaoğlu, C. Balcı, B.B. Doğu, M. Cankurtaran, M.G. Halil Source Type: research
Existing malnutrition screening tools fail to identify 30-60% of malnourished older hospital patients
Rationale: The GLIM identification of malnourished patients start with screening, but do the available screening tools fit into the GLIM construct? We assessed the diagnostic accuracy of five screening tools for malnutrition (SNAQ, MUST, MST, MNA-SF, PG-SGA) against the GLIM criteria in a large diverse hospitalized older population. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: C. van Dronkelaar, M. Tieland, E.M. Reijnierse, P.J. Weijs, H. Kruizenga Source Type: research
