Glycemic effects of daytime compared to overnight home parenteral nutrition infusions in adults with short bowel syndrome
Rationale: In healthy adults, dietary intake late at night is associated with persistent hyperglycemia. However, it is common for patients with short bowel syndrome (SBS) dependent on home parenteral nutrition (HPN) to cycle their infusions overnight. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: H.S. Dashti, A. Leong, K.M. Mogensen, M. Annambhotla, H. Deng, A.N. Carey, D.L. Burns, M.F. Winkler, R. Saxena, C. Compher Source Type: research
Higher metabolic rate during sedentary, eucaloric conditions predicts long-term weight gain: The role of ethnic differences on adjusted energy expenditure
Rationale: In accordance with the concept of energy sensing driving overeating, individuals with relatively higher 24-h energy expenditure (24hEE, adjusted for body composition and demographics) may be more susceptible to gain weight due to disproportionally higher energy intake. However, adjusted 24hEE differs among races/ethnicities with Blacks/Native Americans having on average lower/higher adjusted 24hEE than Whites, respectively. It is unclear whether the relationship between adjusted 24hEE and future weight change may be contingent on ethnic differences in adjusted24hEE. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: T. Hollstein, A. Basolo, T. Ando, J. Krakoff, P. Piaggi Source Type: research
Initial results of an international survey on nutritional issues in patients with cancer
Rationale: Nutritional derangements are prevalent among patients with cancer and lead to poor outcomes. By the present international survey, we aimed at exploring the patients ‘ perspectives on different nutritional aspects during cancer journey (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: A. Molfino, G. Imbimbo, J.-J. Ventura, J. Wesseling, K. Kastrati, M. Muscaritoli Source Type: research
Home parenteral nutrition (HPN) using individually compounded PN via A 7/8/9-Multi-chamber system versus PN via 2/3-chamber bags in subjects with metastatic or localized solid tumors requiring HPN - The IKF-010 Pekannuss trial
This study evaluates whether HPN via Eurotubes improves pt autonomy compared with traditional 2/3-chamber bags. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: S.-E. Al-Batran, I. Roetzer, L. Wohn, W. Blau, T. Zander, K.B. Luley, P. Ivanyi, R.-D. Hofheinz, M. Groschek, J. Kreiss-Sender, C. Baur, T. Wolff, B. Wenning, C. Decker-Baumann, S. Bouymayan, D. Sookthai, M. Schaaf, J. Riedel, T.O. Goetze, G.M. Haag Source Type: research
Intervention with oral nutrition supplements with B-hydroxy-B-methylbutyrate and vitamin D in malnourished oncology outpatients associated with reduced healthcare resource utilization and costs
Rationale: Patients with cancer have special nutrition needs to support them during treatment which can be met with specialized oral nutrition supplements (ONS). We analyzed healthcare resource use and cost data from a retrospective study in malnourished oncology patients that previously reported benefits of an HMB+oral nutritional supplement (HMB-ONS)1. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: I.M. Cornejo-Pareja, K. Kerr, M. Ramirez, M. Camprubi-Robles, I.M. Vegas-Aguilar, J.M. Garcia-Almeida Source Type: research
Effect of nutrition and cross-training routine in body composition, quality of life and physical performance in adults with acute lymphoblastic leukemia de novo during induction phase
Rationale: Patients with acute lymphoblastic leukemia (ALL) undergoing induction therapy decrease their physical capacity, lose muscle mass, and decrease their quality of life. The safety, feasibility, and benefits of exercise during chemotherapy have been proven, but the effects of cross-training exercises have not been analyzed compared with resistance exercises. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: A. G. Gallardo Rodriguez, C. Ramos Pe ñafiel Source Type: research
Managing oral diet following a diagnosis of sub-acute malignant bowel obstruction: Results of the 4-step bounced diet feasibility study
Rationale: Symptom burden is high in patients with malignant bowel obstruction (MBO) and adversely affects oral intake. The 4-step BOUNCED bowel obstruction diet educates patients to self-manage oral intake according to symptoms. It includes clear fluids, thin liquids, pur ée, and soft sloppy foods which are low fibre. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: L. Allan, A. Michael, S.S. Skene, N. Hatchett Source Type: research
Cancer-associated cachexia: Evaluation of lipolysis markers by QRT-PCR in subcutaneous adipose tissue of gastrointestinal cancer patients
Rationale: Enhanced lipolysis and inhibition of adipogenesis are implicated in adipose tissue loss in cachexia. However, these mechanisms are not completely clarified in patients with cancer. We investigated the expression levels of lipolysis-associated genes in subcutaneous adipose tissue (SAT) in newly diagnosed gastrointestinal (GI) cancer patients according to the presence/absence of cachexia (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: A. Molfino, G. Imbimbo, F. Tambaro, E. Ferraro, G. Lauteri, M. Andreini, M. Melena, M.I. Amabile, G. Nigri, M. Muscaritoli Source Type: research
Rectus femoris as a predictor of malnutrition according to glim criteria. VAL-OR group
Rationale: Patients with head and neck cancer (HNC) are at high risk of malnutrition, associated with worse prognosis. Our aim is to evaluate nutritional ultrasound variables as predictors of malnutrition according to GLIM criteria. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: M.T. Zarco-Mart ín, R. Fernández, M.L. Fernández-Soto, G. Olveira, A. Muñoz-Garach, M. González-Pacheco, J. Cobo-Molinos, A. Carmona-Llanos, S. García-Rey, S. Chica-Palomino, F. Torres-Flores, J.M. García-Almeida, VAL-OR Group Source Type: research
DNA methylation signatures in lung cancer patients affected by anorexia
Rationale: The pathophysiology of cancer anorexia is multifactorial and we aimed at evaluating the potential role of epigenetic regulation on those gene expression marks by analyzing changes in methylation on PBMCs DNA of lung cancer patients presenting with poor appetite (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: A. Molfino, G. Imbimbo, F. Ambrosani, F. Tambaro, S. Udali, S. Moruzzi, P. Pattini, A. Castagna, M. Muscaritoli, S. Friso Source Type: research
Study of sarcopenia according to the criteria of mass, muscle strength and function, at the diagnosis of pancreatic cancer: impact on survival
The objectives of our work were to study the diagnosis of pancreatic cancer, the prevalence of sarcopenia with a criterion of muscle mass, strength and function, as well as its impact on survival. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: C. Salacroup, C. David, P. Fayemendy, B. MISSET, L. Charron, E. Rouchaud, T. Vernier, E. Deluche, P. Jesus Source Type: research
Once-weekly (QW) apraglutide decreases parenteral support (PS) in short bowel syndrome with intestinal failure (SBS-IF) and colon-in-continuity (CIC)
Rationale: SBS-IF is a severe organ failure condition with life-long PS dependence. Glucagon-like peptide-2 (GLP-2) stimulates intestinal adaptation resulting in increased absorptive capacity of nutrients and fluids. Apraglutide (APRA) is a novel long-acting synthetic GLP-2 analog in development for SBS-IF. STARS Nutrition is a 52-W phase 2 study in adults with SBS-IF and CiC. This pre-defined interim analysis assesses safety and efficacy of QW subcutaneous APRA in reducing PS at 24W. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: A. Verbiest, M.K. Hvistendahl, F. Bolognani, C. Li, O. Khwaja, P.B. Jeppesen, F. Joly, T. Vanuytsel Source Type: research
Intestinal adaptation and sarcopenia in short bowel syndrome: Results from a prospective study (SARCO-SGC)
Rationale: Malnutrition and sarcopenia are common in short bowel syndrome (SBS, (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: L. Wauters, A. Mohamed, B. de Dreuille, S. Dermine, J. Bettolo, C. Hutinet, E. Lecoq, A. Nuzzo, L. Billiauws, O. Corcos, F. Joly Source Type: research
Gut-skin axis – Effect of Kefir
This study aimed to assess the potential relationship between the ingestion of kefir on both the skin barrier function and gastrointestinal (GI) symptoms, of healthy skin (HS) and AD individuals. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: E. Alves, T. Fontes, J. Greg ório, P. Rijo, C. Rosado, L. Monteiro Rodrigues Source Type: research
High plasma oxalate in short bowel syndrome: never forget the risk of oxalate nephropathy (Oxago study)
Rationale: We aimed to explore the distribution of plasma oxalate (Pox) in enteric hyperoxaluria for short bowel syndrome patients (SBS) to estimate the severity of enteric hyperoxaluria. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - December 1, 2023 Category: Nutrition Authors: C. Grocholski, C. Chambrier, M. Lauverjat, C. Acquaviva, C. Bergoin, N. Abid, J. Bacchetta, L. Derain-Dubourg, S. Lemoine Source Type: research
