Changes in proteomic cargo of circulating extracellular vesicles in response to lifestyle intervention in adolescents with hepatic steatosis
Recent studies suggest that proteomic cargo of extracellular vesicles (EVs) may play a role in metabolic improvements following lifestyle interventions. However, the relationship between changes in liver fat and circulating EV-derived protein cargo following intervention remains unexplored. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 23, 2024 Category: Nutrition Authors: Johanna K. DiStefano, Ignazio S. Piras, Xiumei Wu, Ritin Sharma, Krystine Garcia-Mansfield, Maya Willey, Brooke Lovell, Patrick Pirrotte, Micah L. Olson, Gabriel Q. Shaibi Tags: Original article Source Type: research
Metformin use is associated with reduced mortality risk in diabetic patients with Parkinson's disease
Parkinson's disease (PD) and type-2 diabetes (T2D) arguably share pathophysiologic mechanisms, resulting in a more severe phenotype and progression and diabetes is currently considered a risk factor of PD. Besides, research suggests antidiabetic therapies as potential disease-modifying strategies. The main aim was to assess the impact of a metformin-inclusive antidiabetic treatment on patient all-cause mortality. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 21, 2024 Category: Nutrition Authors: Gianni Pezzoli, Emanuele Cereda, Daniela Calandrella, Michela Barichella, Salvatore Bonvegna, Ioannis U. Isaias Tags: Short Communication Source Type: research
Metformin use is associated with reduced mortality risk in diabetic patients with Parkinson ’s disease
Parkinson ’s disease (PD) and type-2 diabetes (T2D) arguably share pathophysiologic mechanisms, resulting in a more severe phenotype and progression and diabetes is currently considered a risk factor of PD. Besides, research suggests antidiabetic therapies as potential disease-modifying strategies. The main aim was to assess the impact of a metformin-inclusive antidiabetic treatment on patient all-cause mortality. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 21, 2024 Category: Nutrition Authors: Gianni Pezzoli, Emanuele Cereda, Daniela Calandrella, Michela Barichella, Salvatore Bonvegna, Ioannis U. Isaias Tags: Short Communication Source Type: research
Assessment of clinical outcome after sudden alteration of home parenteral nutrition program from customised to commercially premixed admixtures. Experience with short bowel syndrome treatment.
This study aimed to evaluate the mid-term clinical outcome in a group of patients with short bowel syndrome (SBS) after a sudden change in the type of home parenteral nutrition programs from customized to commercially premixed admixtures. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 21, 2024 Category: Nutrition Authors: Konrad Matysiak, Magdalena Szewczuk, Agnieszka Napiera ła, Krzysztof Nowak, Rafał Olijarczyk, Idzi Siatkowski Tags: Original article Source Type: research
An externally validated guide to anatomical interpretation using a direct-vision ( ‘IRIS’) feeding tube
This study externally validated whether an ‘operator guide’ would enable novice operators to differentiate the respiratory and alimentary tracts. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 20, 2024 Category: Nutrition Authors: Stephen J. Taylor, Danielle Milne, Zeino Zeino, Leonard Griffiths, Rowan Clemente, Frances Greer-Rogers, Jules Brown Tags: Original article Source Type: research
An externally validated guide to anatomical interpretation using a direct-vision ('IRIS') feeding tube
This study externally validated whether an 'operator guide' would enable novice operators to differentiate the respiratory and alimentary tracts. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 20, 2024 Category: Nutrition Authors: Stephen J. Taylor, Danielle Milne, Zeino Zeino, Leonard Griffiths, Rowan Clemente, Frances Greer-Rogers, Jules Brown Tags: Original article Source Type: research
Red and processed meat intake and risk of cardiovascular disease: A two-sample Mendelian randomization study
Previous observational studies have yielded inconsistent findings regarding associations between red/processed meat intake and the risk of cardiovascular disease (CVD). Some studies have suggested positive relationships, while others have demonstrated no significant associations. However, causal effects remain uncertain. This 2023 Mendelianrandomization (MR) study investigated the causal relationship between red and processed meat (porkmeat, mutton meat, beef meat)intake and CVD risk by analyzing summary data from the UK Biobank (exposure), CARDIoGRAMplusC4D (coronary artery disease [CAD]), MEGASTROKE (stroke), Nielsen et ...
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Bing Hu, Xin He, Hao Sun, Yongyi Hu, Fei Li, Yanxiang Sun, Jie Sun, Li Feng Tags: Original article Source Type: research
Gut instincts: Unveiling the connection between gut microbiota and Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder marked by neuroinflammation and gradual cognitive decline. Recent research has revealed that the gut microbiota (GM) plays an important role in the pathogenesis of AD through the microbiota-gut-brain axis. However, the mechanism by which GM and microbial metabolites alter brain function is not clearly understood. GM dysbiosis increases the permeability of the intestine, alters the blood –brain barrier permeability, and elevates proinflammatory mediators causing neurodegeneration. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Vasu Peddinti, Manoj Mohan Avaghade, Sunil Umedmal Suthar, Biswajit Rout, Shyam Sudhakar Gomte, Tejas Girish Agnihotri, Aakanchha Jain Tags: Narrative Review Source Type: research
Comment on “Coenzyme Q10 supplementation in rheumatic diseases: A systematic review”
(Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Artur Barbosa Gomes, Lara Rafaela Alves dos Santos, Larissa Alves Guimar ães, Fátima Regina Nunes de Sousa Tags: Letter to the Editor Source Type: research
The association between vitamin C intake and the risk of abdominal aortic calcification: A population-based study
The beneficial effects of dietary vitamin C intake on human health have received widespread attention from the population. However, the correlation between vitamin C intake and abdominal aortic calcification remains unclear. The authors aimed to investigate the relationship between dietary vitamin C intake and AAC in US adults. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Chang Liu, Hao Zhang, Yuwei Yang, Yan Cao, Dan Liang Tags: Original article Source Type: research
The association between tea consumption and non-malignant digestive system diseases: a Mendelian randomized study
Tea consumption might be closely related to non-malignant digestive diseases. Nevertheless, this correlation remains inadequately comprehended. Therefore, our objective was to elucidate the essence of these connections. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Qi Sun, Ning Gao, Jiangwei Song, Junjun Jia, Aiqiang Dong, Weiliang Xia Tags: Original article Source Type: research
Red and Processed Meat Intake and Risk of Cardiovascular Disease: A Two-sample Mendelian Randomization Study
Previous observational studies have yielded inconsistent findings regarding associations between red/processed meat intake and the risk of cardiovascular disease (CVD). Some studies have suggested positive relationships, while others have demonstrated no significant associations. However, causal effects remain uncertain. This 2023 Mendelianrandomization(MR) study investigated the causal relationship between red and processed meat(porkmeat, mutton meat, beef meat)intake and CVD risk by analyzing summary data from the UK Biobank (exposure), CARDIoGRAMplusC4D (coronary artery disease [CAD]), MEGASTROKE (stroke), Nielsen et al...
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Bing Hu, Xin He, Hao Sun, Yongyi Hu, Fei Li, Yanxiang Sun, Jie Sun, Li Feng Tags: Original article Source Type: research
A Case Report of Lactobacillus Bacteremia in a Patient on Chronic Parenteral Nutrition
Short bowel syndrome is a malabsorption disorder typically caused by the physical loss of a portion of the intestine, whereafter the body is unable to adequately absorb nutrients, fluids, and electrolytes. Many patients with short bowel syndrome are reliant on home parenteral nutrition through a tunneled or peripherally inserted central catheter to ensure sufficient hydration and nutrition. Central venous catheters are a nidus for bacteria, and patients are at risk for infections associated with high levels of morbidity and mortality. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Hannah W. Fiske, Breton Roussel, Marion Winkler, Benjamin Hall Tags: Short Communication Source Type: research
Gut Instincts: Unveiling the connection between gut microbiota and Alzheimer ’s disease
Alzheimer's disease (AD) is a neurodegenerative disorder marked by neuroinflammation and gradual cognitive decline. Recent research has revealed that the gut microbiota (GM) plays an important role in the pathogenesis of AD through the microbiota-gut-brain axis. However, the mechanism by which GM and microbial metabolites alter brain function is not clearly understood. GM dysbiosis increases the permeability of the intestine, alters the blood-brain barrier permeability, and elevates proinflammatory mediators causing neurodegeneration. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Vasu Peddinti, Manoj Mohan Avaghade, Sunil Umedmal Suthar, Biswajit Rout, Shyam Sudhakar Gomte, Tejas Girish Agnihotri, Aakanchha Jain Tags: Narrative Review Source Type: research
Factors Affecting the Duration Required for Meal Intake among Postgastrectomy Patients
Patients who had undergone gastrectomy often feel tired during meals as it takes longer for them to consume their meals, as compared to the length preoperatively. We aimed to clarify the factors affecting the duration required for food intake in this population. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - February 19, 2024 Category: Nutrition Authors: Megumi Kitagawa, Yuko Uesugi Tags: Original article Source Type: research
