Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Host Immunity and Immunization Strategies for Clostridioides difficile Infection
Clin Microbiol Rev. 2023 May 10:e0015722. doi: 10.1128/cmr.00157-22. Online ahead of print.ABSTRACTClostridioides difficile infection (CDI) represents a significant challenge to public health. C. difficile-associated mortality and morbidity have led the U.S. CDC to designate it as an urgent threat. Moreover, recurrence or relapses can occur in up to a third of CDI patients, due in part to antibiotics being the primary treatment for CDI and the major cause of the disease. In this review, we summarize the current knowledge of innate immune responses, adaptive immune responses, and the link between innate and adaptive immune ...
Source: Clinical Microbiology Reviews - May 10, 2023 Category: Microbiology Authors: Farha Naz William A Petri Source Type: research
Therapeutics for Vancomycin-Resistant Enterococcal Bloodstream Infections
This article presents an overview of the treatment options for VRE BSIs, the role of antimicrobial dose optimization through TDM in supporting clinical infection management, and challenges and perspectives for the future.PMID:37067406 | DOI:10.1128/cmr.00059-22 (Source: Clinical Microbiology Reviews)
Source: Clinical Microbiology Reviews - April 17, 2023 Category: Microbiology Authors: Kelly A Cairns Andrew A Udy Trisha N Peel Iain J Abbott Michael J Dooley Anton Y Peleg Source Type: research
Therapeutics for Vancomycin-Resistant Enterococcal Bloodstream Infections
This article presents an overview of the treatment options for VRE BSIs, the role of antimicrobial dose optimization through TDM in supporting clinical infection management, and challenges and perspectives for the future.PMID:37067406 | DOI:10.1128/cmr.00059-22 (Source: Clinical Microbiology Reviews)
Source: Clinical Microbiology Reviews - April 17, 2023 Category: Microbiology Authors: Kelly A Cairns Andrew A Udy Trisha N Peel Iain J Abbott Michael J Dooley Anton Y Peleg Source Type: research
