Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research