Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Fungal Endocarditis: Pathophysiology, Epidemiology, Clinical Presentation, Diagnosis, and Management
Clin Microbiol Rev. 2023 Jul 13:e0001923. doi: 10.1128/cmr.00019-23. Online ahead of print.ABSTRACTFungal endocarditis accounts for 1% to 3% of all infective endocarditis cases, is associated with high morbidity and mortality (>70%), and presents numerous challenges during clinical care. Candida spp. are the most common causes of fungal endocarditis, implicated in over 50% of cases, followed by Aspergillus and Histoplasma spp. Important risk factors for fungal endocarditis include prosthetic valves, prior heart surgery, and injection drug use. The signs and symptoms of fungal endocarditis are nonspecific, and a high deg...
Source: Clinical Microbiology Reviews - July 13, 2023 Category: Microbiology Authors: George R Thompson Jeffrey D Jenks John W Baddley James S Lewis Matthias Egger Ilan S Schwartz Johannes Boyer Thomas F Patterson Sharon C-A Chen Peter G Pappas Martin Hoenigl Source Type: research

Bordetella bronchiseptica and Bordetella pertussis: Similarities and Differences in Infection, Immuno-Modulation, and Vaccine Considerations
Clin Microbiol Rev. 2023 Jun 12:e0016422. doi: 10.1128/cmr.00164-22. Online ahead of print.ABSTRACTBordetella pertussis and Bordetella bronchiseptica belong to the genus Bordetella, which comprises 14 other species. B. pertussis is responsible for whooping cough in humans, a severe infection in children and less severe or chronic in adults. These infections are restricted to humans and currently increasing worldwide. B. bronchiseptica is involved in diverse respiratory infections in a wide range of mammals. For instance, the canine infectious respiratory disease complex (CIRDC), characterized by a chronic cough in dogs. At...
Source: Clinical Microbiology Reviews - June 12, 2023 Category: Microbiology Authors: Beatriz Miguelena Chamorro Karelle De Luca Gokul Swaminathan St éphanie Longet Egbert Mundt St éphane Paul Source Type: research

Bordetella bronchiseptica and Bordetella pertussis: Similarities and Differences in Infection, Immuno-Modulation, and Vaccine Considerations
Clin Microbiol Rev. 2023 Jun 12:e0016422. doi: 10.1128/cmr.00164-22. Online ahead of print.ABSTRACTBordetella pertussis and Bordetella bronchiseptica belong to the genus Bordetella, which comprises 14 other species. B. pertussis is responsible for whooping cough in humans, a severe infection in children and less severe or chronic in adults. These infections are restricted to humans and currently increasing worldwide. B. bronchiseptica is involved in diverse respiratory infections in a wide range of mammals. For instance, the canine infectious respiratory disease complex (CIRDC), characterized by a chronic cough in dogs. At...
Source: Clinical Microbiology Reviews - June 12, 2023 Category: Microbiology Authors: Beatriz Miguelena Chamorro Karelle De Luca Gokul Swaminathan St éphanie Longet Egbert Mundt St éphane Paul Source Type: research