Essential Oil Composition of Antidesma cuspidatum and Acetylcholinesterase Inhibitory Activity
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 26, 2024 Category: Chemistry Source Type: research
Water-Soluble Polysaccharides from Datura stramonium Leaves and Their Prebiotic Activity
Polysaccharide constituents including water-soluble polysaccharides, pectic substances, and hemicelluloses were isolated from Datura stramonium L. (Solanaceae) leaves. Their monosaccharide compositions were established. The monomer compositions of the isolated biopolymers included neutral and acidic monosaccharides. Prebiotic activity was found for the water-soluble polysaccharides isolated by cold water. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 26, 2024 Category: Chemistry Source Type: research
A Novel Chromone Alcohol from Portulaca oleracea
A novel chromone alcohol, (S)-3,6,7-trihydroxy-2-(1-(4-hydroxyphenyl)ethyl)-4H-chromen-4-one, was isolated fromPortulaca oleracea L. This compound was named oleracone P. The structure was identified by spectroscopic methods, including 1D, 2D NMR, CD, and UHPLC-ESI-Q-TOF/MS. It was found that oleracone P showed significant biological activity, inhibiting the production of inflammatory factor IL-1β at 20 μM. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 26, 2024 Category: Chemistry Source Type: research
Synthesis of New Amides of 3-O-acetyl-18 β-H-glycyrrhetic Acid
New amides of 3-O-acetyl-18β-H-glycyrrhetic acid with several aromatic and heterocyclic amines were synthesized. The chemical structures of the synthesized compounds were elucidated by UV, IR and NMR spectroscopic and mass spectrometric methods. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 26, 2024 Category: Chemistry Source Type: research
Terpenoids from the Petroleum Ether Extract of Artemisia argyi
The chemical analysis on petroleum ether extract ofArtemisia argyi resulted in the identification of 11 terpenoids, including an undescribed monocyclic monoterpenoid, artemisinicol A (1), along with ten known compounds (2–11). Their structures were elucidated by extensive spectroscopic analysis (including 1D, 2D NMR, and HR-MS) and ECD calculation. Thein vitro tumor growth inhibitory property of the compound1 was further assessed. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 26, 2024 Category: Chemistry Source Type: research
Ethylation And Allylation Reactions of Pinostrobin from the Rhizome of Kaempferia pandurata
This research was designed to isolate pinostrobin fromKaempferia pandurata Roxb. rhizome using a chromatography method and to study its structural modification through ethylation and allylation reactions. Two compounds were afforded from the ethylation reaction that were 5-ethoxy-7-methoxyflavanone and 4 ′-ethoxy-6′-methoxychalcone and in the case of the allylation, 5-O-allylpinostrobin (5-allyloxy-7-methoxyflavanone) and 6-allylpinostrobin (6-allyl-5-hydroxy-7-methoxyflavanone) were obtained. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 15, 2023 Category: Chemistry Source Type: research
Constituents from the Endophytic Fungus of Annulohypoxylon nitens
A chemical study on then-BuOH-soluble fraction of the 95% EtOH extract of rice fermented with the endophytic fungusAnnulohypoxylon nitens has resulted in the isolation of one new natural pyrrole derivative, designated as nitenspyrrole (1), together with 3 known compounds, taraxasterol (2), oleanolic acid (3), andβ-sitostenone (4). Their structures were elucidated by spectroscopic analyses including 1D and 2D NMR experiments, and by ESI-MS. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 10, 2023 Category: Chemistry Source Type: research
Chemical Composition and Larvicidal Activity of Essential Oil from Leaves Eugenia catharinae
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 10, 2023 Category: Chemistry Source Type: research
Two New Isoquinolines from Cigar Tobacco-Derived Endophytic Fungi Aspergillus puniceus and Their Antibacterial Activity
With the aims of screening more antibacterial activity metabolites, in this study, two new (1 and2), together with five known (3 –7) isoquinolines were isolated from the cigar tobacco-derived endophytic fungiAspergillus puniceus. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. The new compounds were evaluated for antibacterial activities againstPseudomonas syringae (the main pathogenic sources of tobacco angular leaf spot disease), and compounds1 and2 exhibited inhibitory effects with MIC50 values of 8.5 and 5.4 μg/mL respectively. These rates are lower than that...
Source: Chemistry of Natural Compounds - November 10, 2023 Category: Chemistry Source Type: research
Chemical Composition and Antimicrobial Properties of Essential Oil from Viburnum lutescens
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 10, 2023 Category: Chemistry Source Type: research
Synthesis and Antimicrobial Activity of Phthalide Derivatives of Cytisine, Anabasine, and Salsoline
Aminophthalide derivatives of cytisine, anabasine, and salsoline were obtained in high yields via condensation of the alkaloids with o-formylbenzoic acid. Their structures were proven using1H and13C NMR spectroscopy and data from 2D COSY1H –1H and HMQC1H –13C spectra. Studies of their antimicrobial activity showed moderate antimicrobial activity of 3-(N-cytisin-1-yl)isobenzofuran-1(3H)-one and 3-(N-salsolin-1-yl)isobenzofuran-1(3H)-one against Gram-positive test strainStaphylococcus aureus ATCC 6538 and Gram-negative test strainEscherichia coli ATCC 25922. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 10, 2023 Category: Chemistry Source Type: research
Index of Natural Objects
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 10, 2023 Category: Chemistry Source Type: research
Synthetic Transformations of Higher Terpenoids. 43. Synthesis and Cytotoxic Properties of New Lambertianic Acid Derivatives at the Carboxylic Group
Lambertianic acid was selectively transformed at the carboxylic group. Synthetic methods for natural labdanoids, i.e., lambertianic acid methyl ester and lambertianol, were proposed. NewN-containing diterpenoid derivatives with alkyl(aryl)amide, dialkylamide, hydrazide,N-hydroxycarbamoyl, and nitrile groups in the C-4 position of the labdane skeleton were synthesized via reactions of lambertianic acid chloride with aliphatic and aromatic amines, amino acids, hydrazine, and hydroxylamine. Compounds with higher cytotoxicity than lambertianic acid against MCF-7, HeLa, and HepG2 (MTT assay) human tumor cell lines were obtained...
Source: Chemistry of Natural Compounds - November 9, 2023 Category: Chemistry Source Type: research
Synthesis and Cytotoxic Activity of a New Derivative of Rupestonic Acid
Twenty new amide derivatives of rupestonic acid were synthesized. Their cytotoxic activities against four human cancer cell lines (HeLa, HT-29, A549, and HepG2) were established. Compound2p was active against A549 (IC50 = 10.31 μM) and HepG2 cell lines (IC50 = 5.44 μM). Derivative2q showed better cytotoxic activity against HeLa (IC50 = 7.95 μM) and HT-29 cancer cells (IC50 = 2.49 μM). (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 9, 2023 Category: Chemistry Source Type: research
Alkaloids from Delphinium oreophilum. The New Diterpene Alkaloid 15-Epinaviculine B
4-{[2-(Methoxycarbonyl)phenyl]amino}-2-methyl-4-oxobutanoic acid amide, the diterpenoid alkaloid delavaine B, and the new talassamine-type alkaloid 15-epinaviculine B were isolated for the first time from the aerial part ofDelphinium oreophilum Huth. The structures of the compounds were elucidated using 1D and 2D NMR spectroscopy, mass spectrometry, and an X-ray crystal structure analysis for the new alkaloid. The stereochemistry of the talassamine framework and H-bonds in the crystal of 15-epinaviculine B were analyzed. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 9, 2023 Category: Chemistry Source Type: research
