New Diterpene Alkaloid from Delphinium paradoxum
The new C20-diterpene hetidine-type alkaloid paradoxine was isolated from the plantDelphinium paradoxum Bunge. Its structure was determined using IR and 2D NMR spectroscopic and mass spectrometric methods. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 30, 2024 Category: Chemistry Source Type: research
Action of Nitrating Mixtures and Mineral Acids on the Quinoline Alkaloids Haplophyllidine and Anhydroperforine
The effects of various acids on the intramolecular cyclization of haplophyllidine (1) were studied. Compound1 was converted at room temperature by H2SO4, HNO3, HClO4, and a nitrating mixture into anhydroperforine (2) whereas AcOH and HCl (35%) did not affect1. Nitration of1 and2 at 65 –70°C led to elimination of MeOH followed by aromatization of ring A and nitration of the furan ring to form 7-methoxy-3,3-dimethyl-9-nitro-2,3-dihydro-1H-furo[2,3-b]pyrano[2,3-h] quinoline (3) and 7-methoxy-3,3-dimethyl-9-nitro-2,3,8,9-tetrahydro-1H-furo[2,3-b]pyrano[2,3-h]quinolin-8-ol (4). Use of Ac2O and HNO3 gave 4,8-dimethoxy-8-(3-me...
Source: Chemistry of Natural Compounds - January 29, 2024 Category: Chemistry Source Type: research
A New Benzenoid of Elaeagnus grandifolia
A new benzenoid, 2,3-(methylenedioxy)-6-methylbenzene-1,4,5-triol (1) and seven known compounds (2 –8) were isolated from the stems ofElaeagnus grandifolia Hayata. The structure of the new benzenoid was elucidated by chemical and physical evidence. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 29, 2024 Category: Chemistry Source Type: research
Chemical Composition and Antioxidant Activity of the Essential Oil of Tabernaemontana dichotoma
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 29, 2024 Category: Chemistry Source Type: research
Constituents of Tanacetopsis karataviensis
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 29, 2024 Category: Chemistry Source Type: research
Secondary Metabolites of Endophytic Fungi Aspergillus terreus
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 29, 2024 Category: Chemistry Source Type: research
Composition and Antibacterial Activity of Essential Oils from Roots of Seseli condensatum
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 29, 2024 Category: Chemistry Source Type: research
Chemical Constituents of Aralia echinocaulis
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 29, 2024 Category: Chemistry Source Type: research
Synthesis and Antichlamydial Activity of Oleanolic Acid Aza-Derivatives
Modification of oleanolic acid synthesized newN-containing derivatives with amino- and azepano-fragments in rings A and C that were highly active againstC. trachomatis with a chemotherapeutic index> 8. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 27, 2024 Category: Chemistry Source Type: research
Metabolites from Cinnamomum subavenium with Anti-Dengue Virus Activity
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 27, 2024 Category: Chemistry Source Type: research
Megastigmanes and Flavonoids from Seeds of Hippophae rhamnoides
Phytochemical investigation of the seeds fromHippophae rhamnoides L. led to the isolation of a new megastigmane, named (6S,9R)-9-hydroxy-4,7-megastigmadien-3-one-9-O-β-D-apiofuranosyl-(1 →6)-β-D-glucopyranoside (1), together with its spatial heterogeneity which is a known megastigmane (2). Compounds3 –13 are flavonoid glycosides, 9 compounds (2,5 –12) of which were isolated from theH. rhamnoides for the first time. Their structures were proposed through HR-ESI-MS,1H, and13C NMR data interpretation. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 27, 2024 Category: Chemistry Source Type: research
Synthesis and Anti-VIBRIO Activity of Gallic Acid Derivatives Containing Thiosemicarbazide
In order to explore new gallic acid derivatives with high antibacterial activity, we synthesize a series of new 1-(3,4,5-trihydroxybenzoyl)-4-(substituted benzoyl)thiosemicarbazide and evaluate their activities againstVibrio harveyi,Vibrio cholerae,Vibrio parahaemolyticus, andVibrio vulnificus in vitro. Through the experiments, we found that compound7d has the best inhibitory activity againstV. harveyi andV. cholerae, the minimum inhibitory concentration (MIC) values were 0.0078 mg/mL and 0.0156 mg/mL; compound7h has the best inhibitory activity againstV. parahaemolyticus andV. vulnificus, with MIC values of 0.0313 mg/mL a...
Source: Chemistry of Natural Compounds - January 27, 2024 Category: Chemistry Source Type: research
Lipids from Seeds of Alhagi persarum
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 27, 2024 Category: Chemistry Source Type: research
A Novel Bibenzyl Derivative of Hydrangea chinensis
A novel bibenzyl derivative, hydrangchin (1) and ten known compounds (2 –11) were isolated from the stems ofHydrangea chinensis Maxim. (Saxifragaceae). The structure of the novel bibenzyl derivative was characterized on the basis of spectral analysis. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 27, 2024 Category: Chemistry Source Type: research
Neolignans from Selaginella trichoclada
A new neolignan, ( –)-(7R,8S,7 ′R,8 ′S,8 ′′S)-4 ′-hydroxy-3′,3′′,5′′-trimethoxy-4′′-O-β-D-glucopyranosyl-7,9,7 ′,9′-diepoxy-3,4,8′′,9′′-bisoxy-8,8′-sesquineolignan (1), and five known neolignan derivatives were isolated from an ethanolic extract ofSelaginella trichoclada Alston. The chemical structure of these compounds was identified by extensive spectroscopic analyses (UV-vis, 1D/2D NMR, CD, and MS). Furthermore, the molecular docking results indicate that compound1 may act as an anti-inflammatory inhibitor. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - January 27, 2024 Category: Chemistry Source Type: research
