Ecological diversity profiles of non-vaccine-targeted HPVs after gender-based community vaccination efforts
Cell Host Microbe. 2023 Nov 8;31(11):1921-1929.e3. doi: 10.1016/j.chom.2023.10.001.ABSTRACTThe long-term effect of population-level human papillomavirus (HPV) vaccination on the viral ecology of the untargeted HPVs is poorly understood. We performed an 8-year follow-up of 33 communities randomized to gender-neutral HPV16/18 vaccination, girls-only HPV16/18 vaccination, and control communities without HPV vaccination. The 1992/93 and 1994 birth cohorts were invited in school years 2007/8 and 2008/9. Follow-up cervico-vaginal sampling at 18 and 22 years of age, 4 and 8 years post-vaccination, respectively, were attended by 1...
Source: Cell Host and Microbe - November 9, 2023 Category: Microbiology Authors: Ville N Pimenoff Penelope Gray Karolina Louvanto Tiina Eriksson Camilla Lagheden Anna S öderlund-Strand Joakim Dillner Matti Lehtinen Source Type: research
Multi-kingdom gut microbiota analyses define bacterial-fungal interplay and microbial markers of pan-cancer immunotherapy across cohorts
This study provides a fungal profile of the ICI response and the identification of multi-kingdom microbial markers with good performance that may improve the overall applicability of ICI therapy.PMID:37944495 | DOI:10.1016/j.chom.2023.10.005 (Source: Cell Host and Microbe)
Source: Cell Host and Microbe - November 9, 2023 Category: Microbiology Authors: Xiaowen Huang Muni Hu Tiantian Sun Jiantao Li Yilu Zhou Yuqing Yan Baoqin Xuan Jilin Wang Hua Xiong Linhua Ji Xiaoqiang Zhu Tianying Tong Lijun Ning Yanru Ma Ying Zhao Jinmei Ding Zhigang Guo Youwei Zhang Jing-Yuan Fang Jie Hong Haoyan Chen Source Type: research
One receptor, two worlds: MXRA8's alphavirus tango
Cell Host Microbe. 2023 Nov 8;31(11):1763-1764. doi: 10.1016/j.chom.2023.10.008.ABSTRACTMammalian MXRA8 functions as a receptor for chikungunya and other related alphaviruses. A recent study in Cell molecularly characterizes host-specific receptor usage, specifically showing avian MXRA8 acts as a receptor for several alphaviruses with avian reservoirs in an inverted manner relative to alphaviruses that use mammalian MXRA8 as a receptor.PMID:37944485 | DOI:10.1016/j.chom.2023.10.008 (Source: Cell Host and Microbe)
Source: Cell Host and Microbe - November 9, 2023 Category: Microbiology Authors: James Weger-Lucarelli Source Type: research
Intricate guard-guardee interplay in plant immune signaling
Cell Host Microbe. 2023 Nov 8;31(11):1764-1766. doi: 10.1016/j.chom.2023.10.010.ABSTRACTPlant helper NLRs are immune signal transducers. In this issue of Cell Host & Microbe, Wang et al. report that the ADR1 subfamily of helper NLRs in Arabidopsis thaliana is functionally diversified to cope with the perturbation by bacterial pathogen effector and is guarded by the NLR protein SNC1.PMID:37944486 | DOI:10.1016/j.chom.2023.10.010 (Source: Cell Host and Microbe)
Source: Cell Host and Microbe - November 9, 2023 Category: Microbiology Authors: Takaki Maekawa Source Type: research
Meet the extended Segatella copri complex
Cell Host Microbe. 2023 Nov 8;31(11):1766-1769. doi: 10.1016/j.chom.2023.10.009.ABSTRACTThe Segatella copri complex contains key members of the human gut microbiome, but their genetic diversity and associations with health are incompletely understood. In this issue of Cell Host & Microbe, Blanco-Míguez et al. expand the S. copri complex to 13 species and reveal species-specific associations with lifestyle and health.PMID:37944487 | DOI:10.1016/j.chom.2023.10.009 (Source: Cell Host and Microbe)
Source: Cell Host and Microbe - November 9, 2023 Category: Microbiology Authors: Ye Peng Hein M Tun Source Type: research
