Multimorbidity and readmissions in older people with acute coronary syndromes
Conclusions: O lder people with ACS have a high multimorbidity burden and a high readmission rate both within 30-days and one-year. Half of the readmissions were due to a cardiovascular event or a bleeding event. The presence of multimorbidity increases the risk of readmissions for patients with ACS. As hospital a dmissions are costly for the health care system and can include risks, especially for older patients, there may be opportunities in better risk stratifying this group at discharge for subsequent decrease in readmission rates. (Source: Cardiology)
Source: Cardiology - January 18, 2022 Category: Cardiology Source Type: research
Emerging Technologies in Electrophysiology: From Single-Chamber to Biventricular Leadless Pacemakers
Background: Transvenous pacemakers have been shown to improve quality of life and mortality in patients with bradycardia and cardiac conduction blocks. However, they possess inevitable drawbacks as they have a relatively high incidence of lead and device pocket-related complications. Therefore, leadless pacemakers have emerged as a solution to reduce the complications seen with conventional pacemakers. However, there have been no clinical trials to date comparing transvenous to leadless pacemakers.Summary: Currently, the Micra™ transcatheter pacing system or AV device has been approved for commercial use worldwide but is...
Source: Cardiology - January 17, 2022 Category: Cardiology Source Type: research
Emerging Technologies in Electrophysiology: From Single Chamber to Biventricular Leadless Pacemakers
Background:
Transvenous pacemakers have been shown to improve quality of life and mortality in patients with bradycardia and cardiac conduction blocks. However, they possess inevitable drawbacks as they have a relatively high incidence of lead and device pocket-related complications. Therefore, leadless pacemakers have emerged as a solution to reduce the complications seen with conventional pacemakers. However, there have been no clinical trials to date comparing transvenous to leadless pacemakers.
Summary:
Currently, the Micra TPS or AV device has been approved for commercial use worldwide but is limited to single-...
Source: Cardiology - January 17, 2022 Category: Cardiology Source Type: research
Could the PARIS Risk Scores Be Useful for the Choice of Triple vs Dual Antithrombotic Therapy in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention?
Conclusion. Our data suggest that some variables associated with increased TR or BR are poorly considered in the daily practice while the use of PARIS scales could help in the implementation of guidelines' recommendations. (Source: Cardiology)
Source: Cardiology - January 11, 2022 Category: Cardiology Source Type: research
Cardiovascular Disease, Cancer, and Multimorbidity Interactions: Clinical Implications
Background: With the aging population, the frequency of cardiovascular disease (CVD), cancer, and other morbid conditions is increasing dramatically. In addition, one disease may affect the other leading to a vicious cycle.Summary: With aging, the function of organs and systems of the human body declines including the immune system resulting in a diminished response to various pathogens and a chronic inflammatory process; these changes, in addition to other risk factors, contribute to the development of multiple morbid conditions including CVD and cancer. Multimorbidity in the elderly has become the rule rather than the ex...
Source: Cardiology - January 5, 2022 Category: Cardiology Source Type: research
Cardiovascular Disease, Cancer and Multimorbidity Interactions: Clinical Implications
Background: With the aging population, the frequency of cardiovascular disease (CVD), cancer and other morbid conditions are increasing dramatically. In addition, one disease may affect the other leading to a vicious cycle.
Summary: With aging, the function of organs and systems of the human body decline including the autoimmune system resulting in a diminished response to various pathogens and a chronic inflammatory process; these changes, in addition to other risk factors, contributes to the development of multiple morbid conditions including CVD and cancer. Multimorbidity in the elderly has become the rule rather than...
Source: Cardiology - January 5, 2022 Category: Cardiology Source Type: research
Prognostic Importance of Pulmonary Artery Pulsatility Index and Right Ventricular Stroke Work Index in End-Stage Heart Failure Patients
Conclusion: The low PAPi was an ind ependent risk for ACE and it had a linear association with it. However, RVSWI seems to be have a nonlinear association with ACE (J-curve pattern). (Source: Cardiology)
Source: Cardiology - January 3, 2022 Category: Cardiology Source Type: research
Unicuspid aortic valve: a rare congenital anomaly
Unicuspid aortic valve (UAV) is a rare congenital aortic valve anomaly. It has two subtypes and often is associated with aortic valve dysfunction and corresponding clinical presentations. Echocardiography is the first choice of diagnostic method for UAV. Three-dimensional echocardiography has played an increasingly important role in diagnosis, intraprocedural guidance, and post-procedural assessment in recent years. There remain challenges in distinguishing UAV from bicuspid aortic valve (BAV) or tricuspid aortic valve (TAV). Misdiagnosis is most resulted from raphes or leaflet calcifications. Multi-modality imaging has ob...
Source: Cardiology - December 29, 2021 Category: Cardiology Source Type: research
Exhaled Methane is Associated with a Lower Heart Rate
Conclusion: Our findings suggest a potential role for the microbiome (and specifically CH4 from methanogens) to regulate heart rate. Considering these findings, mechanistic studies are warranted to further investigate this potential novel microbiome-neurocardiac axis. (Source: Cardiology)
Source: Cardiology - December 13, 2021 Category: Cardiology Source Type: research
Reply: “Possible Takotsubo Syndrome” – A Refreshing Start toward the Path to Detect the True Prevalence of Takotsuobo Syndrome
(Source: Cardiology)
Source: Cardiology - December 13, 2021 Category: Cardiology Source Type: research
Reply: “Possible Takotsubo Syndrome”: A Refreshing Start Towards the path to Detect the True Prevalence of Takotsuobo Syndrome
Not applicable (Source: Cardiology)
Source: Cardiology - December 13, 2021 Category: Cardiology Source Type: research
Drug-Eluting versus Bare-Metal Stents in Saphenous Vein Grafts Compared to Native Coronary Vessels: The Norwegian Coronary Stent Trial Study
Conclusion: In SVG, no difference in TLR between DES and BMS was observed after 5 years in contrast to persistent benefit in native vessels. The high rate of TLR and MI in SVG makes treatment of native vessels a preference whenever feasible and better treatment options for SVG are warranted.Cardiology (Source: Cardiology)
Source: Cardiology - December 8, 2021 Category: Cardiology Source Type: research
Drug-eluting versus bare metal stents in saphenous vein grafts compared to native coronary vessels. The NORSTENT study.
Abstract.
Background.
Drug-eluting stents (DES) reduce target lesion revascularization (TLR) with no effect on mortality or myocardial infarction (MI) compared to bare metal stents (BMS) in native vessels. Randomized stent studies in saphenous vein grafts (SVG) are few and the reported effects are ambiguous. The NORSTENT study is the first to randomize lesions to percutaneous coronary intervention (PCI) in native vessels and SVG.
Aims.
To compare rate of mortality, MI and TLR across stent and vessel types.
Methods.
In this substudy 6087 patients with a single lesion in native vessels and 164 in SVG, were followed for...
Source: Cardiology - December 8, 2021 Category: Cardiology Source Type: research
Role of Signaling Pathways during Cardiomyocyte Differentiation of Mesenchymal Stem Cells
Multipotent stem cells, including mesenchymal stem cells (MSCs), represent a promising source to be used by regenerative medicine. They are capable of performing myogenic, chondrogenic, osteogenic and adipogenic differentiation. Also, MSCs are characterized by the expression of multiple surface antigens, but none of them appears to be particularly expressed on MSCs. Moreover, the prospect of monitoring and controlling MSC differentiation is a scientifically crucial regulatory and clinical requirement. Different transcription factors and signaling pathways are involved in cardiomyocyte differentiation. Due to the paucity of...
Source: Cardiology - December 3, 2021 Category: Cardiology Source Type: research
“Possible Takotsubo Syndrome”: A Refreshing Start Towards the Path to Detect the True Prevalence of Takotsubo Syndrome
No Abstract (Source: Cardiology)
Source: Cardiology - December 3, 2021 Category: Cardiology Source Type: research
