Importance and Assessment of Quality of Life in Symptomatic Permanent Atrial Fibrillation: Patient Focus Groups from the RATE-AF Trial
Conclusions: The impact of comorbidities is poorly appreciated in the context of AF, with considerable variability in QoL that requires both generic and AF-specific assessment. Improvement in QoL should direct the appraisal, and reappraisal, of treatment decisions for patients with permanent AF.Cardiology (Source: Cardiology)
Source: Cardiology - August 28, 2020 Category: Cardiology Source Type: research

One-Year Course of Periprocedural Anticoagulation in Atrial Fibrillation Ablation: Results of a German Nationwide Survey
Conclusion: Our survey shows marked heterogeneous periprocedural OAC management at experienced EP centers in Germany. Whereas continuation of VKA has already been integrated into clinical practice, the majority of centers still use a minimally interrupted NOAC strategy.Cardiology (Source: Cardiology)
Source: Cardiology - August 27, 2020 Category: Cardiology Source Type: research

The Interplay between Features of Plaque Vulnerability and Hemodynamic Relevance of Coronary Artery Stenoses
Conclusion: The current study demonstrated that for a given stenosis geometry, features of plaque vulnerability such as necrotic core volume, TCFA, and positive remodeling may influence the hemodynamic relevance of intermediate coronary stenoses.Cardiology (Source: Cardiology)
Source: Cardiology - August 26, 2020 Category: Cardiology Source Type: research

Elimination of Benign Ventricular Premature Beats or Ventricular Tachycardia with Catheter Ablation versus Two Different Optimal Antiarrhythmic Drug Treatment Regimens (Sotalol or Verapamil/Flecainide)
Background: Symptomatic idiopathic ventricular arrhythmias (VA), including premature beats (VPB) and nonsustained ventricular tachycardia (VT) are commonly encountered arrhythmias. Although these VA are usually benign, their treatment can be a challenge to primary and secondary health care providers. Mainstay treatment is comprised of antiarrhythmic drugs (AAD) and, in case of drug intolerance or failure, patients are referred for catheter ablation to tertiary health care centers. These patients require extensive medical attention and drug regimens usually have disappointing results. A direct comparison between the efficac...
Source: Cardiology - August 25, 2020 Category: Cardiology Source Type: research

A Simplified Two-Stepwise Electrocardiographic Algorithm to Distinguish Left from Right Ventricular Outflow Tract Tachycardia Origin
Conclusions: The combination of TZ index #x3c;0 and V2S/V3R index ≤1.5 is a simple and efficient stepwise electrocardiographic algorithm for predicting LVOT origin. For the OT-VAs with a V3-lead precordial transition, the integration of V2S/V3R index ≤1.5 and R-wave deflection interval in lead V3 #x3e;80 ms would be a better choice.Cardiology (Source: Cardiology)
Source: Cardiology - August 25, 2020 Category: Cardiology Source Type: research

Hypertensive Disorders of Pregnancy and Risk of Cardiovascular Disease-Related Morbidity and Mortality: A Systematic Review and Meta-Analysis
Conclusions: Women with a history of HDP are at an increased risk of future CVD-related morbidity and mortality. Our study highlights the importance of life-long monitoring of cardiovascular risk factors in women with a history of HDP.Cardiology (Source: Cardiology)
Source: Cardiology - August 25, 2020 Category: Cardiology Source Type: research

Advances in Cardiac Computed Tomography Functional Imaging Technology
Cardiovascular disease (CVD) is the leading cause of death among patients in China, and cardiac computed tomography (CT) is one of the most commonly used examination methods for CVD. Coronary artery CT angiography can be used for the morphologic evaluation of the coronary artery. At present, cardiac CT functional imaging has become an important direction of development of CT. At present, common CT functional imaging technologies include transluminal attenuation gradient, stress dynamic CT myocardial perfusion imaging, and CT-fractional flow reserve. These three imaging modes are introduced and analyzed in this review.Cardi...
Source: Cardiology - August 23, 2020 Category: Cardiology Source Type: research

Cardiac CT: A Sine Qua Non for Structural Heart Interventions
Cardiology (Source: Cardiology)
Source: Cardiology - August 23, 2020 Category: Cardiology Source Type: research

Heavy Drinking Habits Are Associated with Worse In-Hospital Outcomes in Patients with Acute Coronary Syndrome: An Insight from the AMIS Plus Registry
Conclusions: Our results support that heavy alcohol consumption is an independent predictor of in-hospital mortality in patients presenting with ACS.Cardiology (Source: Cardiology)
Source: Cardiology - August 20, 2020 Category: Cardiology Source Type: research

A Novel Gain-of-Function < b > < i > KCND3 < /i > < /b > Variant Associated with Brugada Syndrome
In conclusion, a novelKCND3 heterozygous variant was associated with BrS. The increased Ito current explained the critical role ofKCND3 in the pathogenesis of BrS. Genetic screening forKCND3 could be useful for understanding the pathogenesis of BrS and providing effective risk stratification in the clinic.Cardiology (Source: Cardiology)
Source: Cardiology - August 20, 2020 Category: Cardiology Source Type: research

Effectiveness and Safety of the European Society of Cardiology 0-/1-h Troponin Rule-Out Protocol: The Design of the ESC-TROP Multicenter Implementation Study
Chest pain is one of the most common complaints at the emergency department (ED), and it is commonly the perceived likelihood of acute coronary syndrome (ACS) that drives management. Guidelines from the European Society of Cardiology (ESC) recommend the use of a 0-/1-h high-sensitivity cardiac troponin T (hs-cTnT) protocol to rule out or in ACS, but this is mostly based on observational studies. The aim of the ESC-TROP trial is to determine the safety and effectiveness of the ESC 0-/1-h hs-cTnT protocol when implemented in routine care. Adult chest pain patients at 5 EDs in the Sk åne Region, Sweden, are included in the t...
Source: Cardiology - August 20, 2020 Category: Cardiology Source Type: research

Transcatheter Closure of Atrial Septal Defects with Cardiac Computed Tomography Sizing: Eight-Year Single-Center Practice
Conclusions: Cardiac CT seems to be comparable to TEE in the assessment of ASD, and transcatheter closure of ASD based on CT sizing alone is safe and feasible.Cardiology (Source: Cardiology)
Source: Cardiology - August 19, 2020 Category: Cardiology Source Type: research

Clinical Outcomes following Left Atrial Appendage Occlusion: A Single-Center Experience
Conclusions: This observational study showed no statistically significant difference in bleeding risk related to initial antithrombotic choice. Smaller device sizes were associated with thromboembolic events, and longitudinal PDL assessment using transesophageal echocardiography showed these frequently do not decrease in size. Larger studies are needed.Cardiology (Source: Cardiology)
Source: Cardiology - August 18, 2020 Category: Cardiology Source Type: research

Two-Hour Post-Load Plasma Glucose, a Biomarker to Improve the GRACE Score in Patients without Known Diabetes
Conclusions: 2h-PG, but not FPG, improves performance of GRS-containing models in predicting post-ACS prognosis in the short to medium term.Cardiology (Source: Cardiology)
Source: Cardiology - August 12, 2020 Category: Cardiology Source Type: research

Gender Differences in Patients Admitted to a Certified German Chest Pain Unit: Results from the German Chest Pain Unit Registry
Conclusion: This study points out gender-specific differences in prehospital time intervals and a significantly higher percentage of atypical symptoms in suspected myocardial ischemia as well as more noncoronary diagnoses in women. Symptom awareness and a broader diagnostic workup in women are essential.Cardiology (Source: Cardiology)
Source: Cardiology - August 11, 2020 Category: Cardiology Source Type: research