Sex Disparities in the Treatment of Aortic Stenosis and Related Outcomes: An Analysis of the National Inpatient Sample
This study sought to examine the impact of sex on outcomes following aortic valve replacement (AVR) for aortic stenosis (AS) in the era of routine TAVR.
Methods
We performed a cross-sectional analysis of the National Inpatient Sample (2009-18) to study AS visits for all AVR, and in-hospital outcomes as a function of sex. Survey estimation commands were used to provide national estimates.
Results
There were an estimated 431,344 surgical aortic valve replacement (SAVR) and 189,137 TAVR inpatient visits. Mortality was higher in women after SAVR (3.8% ±0.1 vs 2.7%±0.07, p (Source: Cardiology)
Source: Cardiology - September 14, 2022 Category: Cardiology Source Type: research
Prediction of left ventricular reverse remodelling: mini review on clinical aspects
Improvement of left ventricular ejection fraction (LVEF) in patients after the first manifestation of heart failure with reduced ejection (HFrEF) has currently been observed more frequently than it was years ago. This appears to be due to the early initiation of comprehensive HF therapy. According to these observations, a new HF syndrome category, heart failure with improved ejection fraction (HFimpEF), was introduced. In this short review, we present definitions of reverse remodelling, myocardial remission and myocardial recovery. We provide an overview of clinical research aimed at evaluating reverse remodelling in diffe...
Source: Cardiology - September 14, 2022 Category: Cardiology Source Type: research
Feasibility, Efficiency, and Safety of Zero-Fluoroscopy Catheter Interventions for Right-Sided Cardiac Arrhythmias Using Only Electroanatomic Mapping
Conclusion: A ZF approach using only electroanatomic mapping without additional invasive procedures to diagnose and treat right-sided cardiac arrhythmias is feasible, efficient, and safe. (Source: Cardiology)
Source: Cardiology - August 17, 2022 Category: Cardiology Source Type: research
Feasibility, Efficiency and Safety of Zero-Fluoroscopy Catheter Interventions for Right-sided Cardiac Arrhythmias using only Electroanatomic Mapping
Conclusion: A zero-fluoroscopy approach using only electroanatomic mapping without additional invasive procedures to diagnose and treat right-sided cardiac arrhythmias is feasible, efficient, and safe. (Source: Cardiology)
Source: Cardiology - August 17, 2022 Category: Cardiology Source Type: research
All-Cause Mortality and Trimethylamine N-Oxide Levels in Patients with Cardiovascular Disease
Conclusions: Despite the promising results of previous studies, our study shows that the level of TMAO has at most moderate value in predicting all-cause mortality. TMAO levels depend on other clinical variables, which limits the use of TMAO as an independent predictor of mortality in these patients. (Source: Cardiology)
Source: Cardiology - August 15, 2022 Category: Cardiology Source Type: research
All-cause mortality and trimethylamine-N-oxide levels in patients with cardiovascular disease
Introduction: Trimethylamine N-oxide (TMAO) is an organic compound with a well-established involvement in the pathogenesis of cardiovascular disease (CVD). However, data on the links between TMAO levels and cardiovascular mortality in Polish patients are lacking.
Objectives: We aimed to assess the relationship between serum TMAO levels and 5-year mortality in Polish patients with CVD.
Patients and methods: We retrospectively assessed serum TMAO levels in 1036 consecutive patients (median age, 62 years; men, 61%) hospitalized between 2013 and 2015. Correlations between TMAO levels and 5-year mortality as well as anthropom...
Source: Cardiology - August 15, 2022 Category: Cardiology Source Type: research
Impact of Prosthetic Valve Regurgitation Assessed by Echocardiography and Magnetic Resonance Imaging on Long-term Clinical Outcomes after TAVR
Background:
Prosthetic valve regurgitation (PVR) impairs early and mid-term outcomes after transcatheter aortic valve replacement (TAVR). We explored the impact of PVR assessed by transthoracic echocardiography (TTE) and magnetic resonance imaging-regurgitation fraction (MRI-RF) on long-term clinical outcomes.
Methods:
PVR was assessed by TTE applying the Valve Academic Research Consortium criteria and MRI-RF (from velocity-encoded phase contrast magnetic resonance sequence) in 424 patients.
Results:
MRI-RF correlated modestly with the echocardiographic grades of PVR (Spearman's rank correlation coefficient= 0.32, p (Source: Cardiology)
Source: Cardiology - August 10, 2022 Category: Cardiology Source Type: research
Prolonged QT interval in athletes: Distinguishing between pathology and physiology
Background: The physiological QT prolongation in athletes is expected to widen the grey zone between physiology and pathology of QT, increasing the diagnostic challenges encountered in athletes with QT prolongation.
Summary: According to International recommendations for electrocardiogram (ECG) in athletes, further evaluation for long QT syndrome (LQTS) is indicated in male athletes with corrected QTc ≥470 ms and in female athletes with QTc≥480 ms. Apart from corrected QT (QTc)≥500 ms, diagnostic challenges arise in borderline cases of QTc prolongation, where further clinical investigations are needed to be performe...
Source: Cardiology - August 10, 2022 Category: Cardiology Source Type: research
Estimating the effect of tafamidis on cardiovascular-related hospitalization in NYHA class III patients with transthyretin amyloid cardiomyopathy in the presence of death
Conclusions: Initial data from ATTR-ACT likely underestimated the effect of tafamidis on CV-related hospitalizations due to the confounding effect of death. When SA CE was used to adjust for survivor bias, there was a 24% reduction in the frequency of CV-related hospitalization in NYHA class III patients treated with tafamidis. (Source: Cardiology)
Source: Cardiology - July 19, 2022 Category: Cardiology Source Type: research
Detecting Coronary Artery Disease using Exhaled Breath Analysis
Conclusion: This proof-of-concept study shows that breath analysis has the potential to be used as a novel rapid, non-invasive diagnostic tool to help identify presence of CAD in patients with acute chest pain. (Source: Cardiology)
Source: Cardiology - July 12, 2022 Category: Cardiology Source Type: research
Assessment of intracoronary adenosine-induced hyperemia in patients with atrial fibrillation in comparison with patients in sinus rhythm
Conclusion:
There is equivalent hyperemic response in FFR-guided revascularization in AF versus SR population. Our findings support the use of FFR in evaluating intermediate coronary stenosis in AF. (Source: Cardiology)
Source: Cardiology - July 4, 2022 Category: Cardiology Source Type: research
The impact of radiofrequency wide circumferential pulmonary vein isolation on left atrial geometry in patients with recurrent atrial fibrillation
Abstract:
Purpose: To investigate the effect of wide area circumferential radiofrequency catheter ablation (WACA) pulmonary vein isolation (PVI) on left atrial (LA) geometry.
Methods: Seventy-one patients underwent WACA, for recurrent paroxysmal (n=31) and persistent (n=40) atrial fibrillation (AF). A three-dimension rotational angiography (3D-RA) of the LA was obtained immediately prior to index and repeat procedure.
Results: Significant reduction of LA volume (65.6 14 ml/m2 vs 62.2 15 ml/m2, p (Source: Cardiology)
Source: Cardiology - June 3, 2022 Category: Cardiology Source Type: research
The possibility of hypersensitivity myocarditis following COVID-19 vaccines: Implications for contrast echocardiography
Response to the comments by Kounis and colleagues on our recent article “Incidence, clinical presentation and management of myocarditis following mRNA-based Covid-19 vaccines: A brief report”, published in Cardiology. We focus on the pharmacological aspects of hypersensitivity myocarditis related to mRNA-based COVID-19 vaccines, which is believed to be caused by the excipient polyethylene glycol (PEG), and show a clinically relevant association between anaphylactic reactions to mRNA-based COVID-19 vaccines and ultrasound contrast agents (UCA). We include hitherto unpublished observations on the frequency of anaphylacti...
Source: Cardiology - June 3, 2022 Category: Cardiology Source Type: research
Association of soluble suppression of tumorigenicity 2 with new-onset atrial fibrillation in acute myocardial infarction
Conclusion sST2 is an independent predictor of new-onset AF in patients with AMI and can improve the accuracy of the AF risk model. (Source: Cardiology)
Source: Cardiology - May 17, 2022 Category: Cardiology Source Type: research
Risk factors and heart rate variability associated with left ventricular enlargement in patients with frequent premature ventricular contractions
This study aimed to investigate the risk factors and HRV for LV enlargement in patients with Frequent PVCs.
Methods: Patients with frequent PVCs (n=571), whose PVC burden counts> 10000/24h or PVC burden> 10%, were recruited. Patients were divided into LV enlargement group (n=161), defined as female left ventricular end-diastolic diameter (LVEDD)> 49.8 mm or male LVEDD> 54.2 mm, and LV normal group (n=410). Two groups were compared on their clinical, electrocardiographic, and HRV parameters. Logistic regression analysis was used to predict the risk factors of LV enlargement in patients with frequent PVCs. The parameters of...
Source: Cardiology - May 12, 2022 Category: Cardiology Source Type: research
